Transgenic epigenetics: using transgenic organisms to examine epigenetic phenomena

scientific article published on 27 March 2012

Transgenic epigenetics: using transgenic organisms to examine epigenetic phenomena is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1155/2012/689819
P932PMC publication ID3335706
P698PubMed publication ID22567397
P5875ResearchGate publication ID224920077

P2093author name stringLori A McEachern
P2860cites workGenomic imprinting in mammals: emerging themes and established theoriesQ21145256
DNA methylation patterns and epigenetic memoryQ22065780
Parental imprinting of the mouse H19 geneQ22122365
CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2Q24295238
Human SRCAP and Drosophila melanogaster DOM are homologs that function in the notch signaling pathwayQ24529979
Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencingQ24536235
Regulation of chromatin by histone modificationsQ24635070
On the origin and functions of RNA-mediated silencing: from protists to manQ24657546
The role of chromatin during transcriptionQ27860995
The Arabidopsis thaliana MEDEA Polycomb group protein controls expression of PHERES1 by parental imprintingQ59510192
Genotype-specific modifiers of transgene methylation and expression in the zebrafish, Danio rerioQ72237925
Deletion of a nuclease-sensitive region between the Igf2 and H19 genes leads to Igf2 misregulation and increased adiposityQ73707646
Genomic imprinting in Drosophila is maintained by the products of Suppressor of variegation and trithorax group, but not Polycomb group, genesQ74813438
A human H19 transgene exhibits impaired paternal-specific imprint acquisition and maintenance in miceQ77658784
Establishing the epigenetic status of the Prader-Willi/Angelman imprinting center in the gametes and embryoQ80563734
Maternal and paternal alleles exhibit differential histone methylation and acetylation at maize imprinted genesQ81768504
Polycomb group complexes self-regulate imprinting of the Polycomb group gene MEDEA in ArabidopsisQ82780023
Tissue- and expression level-specific chromatin looping at maize b1 epialleles.Q51741969
The human and mouse H19 imprinting control regions harbor an evolutionarily conserved silencer element that functions on transgenes in Drosophila.Q52005553
Polycomb, pairing and PIWI--RNA silencing and nuclear interactions.Q52011214
Differential acetylation of histones H3 and H4 in paternal and maternal germline chromosomes during development of sciarid flies.Q52112409
Disruption of mesodermal enhancers for Igf2 in the minute mutant.Q52122005
Elucidation of the minimal sequence required to imprint H19 transgenes.Q52135344
mediator of paramutation1 is required for establishment and maintenance of paramutation at multiple maize loci.Q52144523
Deletion of a silencer element in Igf2 results in loss of imprinting independent of H19.Q52164786
Imprinting of Igf2 and H19 from a 130 kb YAC transgene.Q52192416
Comparative analysis of Igf-2/H19 imprinted domain: identification of a highly conserved intergenic DNase I hypersensitive region.Q52213159
Function of the Polycomb protein is conserved in mice and flies.Q52536715
An imprinting element from the mouse H19 locus functions as a silencer in Drosophila.Q52553227
Directional gene silencing induced by a complex subtelomeric satellite from Drosophila.Q52567651
DNA methylation in Drosophila melanogaster.Q52584665
Polycomb-group proteins are involved in silencing processes caused by a transgenic element from the murine imprinted H19/Igf2 region in Drosophila.Q52606062
Methylation of histone H3 at Lys4 differs between paternal and maternal chromosomes in Sciara ocellaris germline development.Q52673568
CTCF binding is not the epigenetic mark that establishes post-fertilization methylation imprinting in the transgenic H19 ICR.Q54156030
Parental imprinting of the mouse insulin-like growth factor II gene.Q55052428
The two-domain hypothesis in Beckwith–Wiedemann syndrome: autonomous imprinting of the telomeric domain of the distal chromosome 7 clusterQ58134238
Sequence specificity of methylation in higher plant DNAQ59066718
Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 geneQ28145754
CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locusQ28145756
Regulation of heterochromatin by histone methylation and small RNAsQ28261891
Paramutation in maize: RNA mediated trans-generational gene silencingQ28273129
An enhancer deletion affects both H19 and Igf2 expressionQ28288348
Paramutation: from maize to miceQ28289966
Genome regulation by polycomb and trithorax proteinsQ28289984
RNAi-mediated pathways in the nucleusQ28300961
Intergenic transcripts regulate the epigenetic state of rRNA genesQ28593840
The role of DNA methylation, nucleosome occupancy and histone modifications in paramutationQ29400675
Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assemblyQ29614718
Epigenetics in cancerQ29617139
Meiotic pairing and imprinted X chromatin assembly in Caenorhabditis elegansQ30411914
An upstream repressor element plays a role in Igf2 imprintingQ30684867
A dominant mutation in mediator of paramutation2, one of three second-largest subunits of a plant-specific RNA polymerase, disrupts multiple siRNA silencing processesQ30912369
Two-step recruitment of RNA-directed DNA methylation to tandem repeatsQ33263577
The Drosophila homolog of the mammalian imprint regulator, CTCF, maintains the maternal genomic imprint in Drosophila melanogasterQ33645894
H19 imprinting control region methylation requires an imprinted environment only in the male germ line.Q33648826
An intragenic methylated region in the imprinted Igf2 gene augments transcription.Q33757992
Transgenic expression of CBBP, a CXC domain protein, establishes paramutation in maizeQ33777880
Genomic imprinting in plants: observations and evolutionary implicationsQ33918746
Conservation and divergence of methylation patterning in plants and animalsQ33928315
Paramutation, an allelic interaction, is associated with a stable and heritable reduction of transcription of the maize b regulatory geneQ33961926
Investigation of elements sufficient to imprint the mouse Air promoterQ33969040
Transgene repeat arrays interact with distant heterochromatin and cause silencing in cis and transQ33971190
Conservation of heterochromatin protein 1 functionQ33975076
The properties, origin, and mechanism of conversion-type inheritance at the B locus in maizeQ33983138
RNA polymerase IV directs silencing of endogenous DNA.Q33984841
Allele-specific non-CpG methylation of the Nf1 gene during early mouse developmentQ34108779
Genome-wide evolutionary analysis of eukaryotic DNA methylation.Q34110385
CTCF is conserved from Drosophila to humans and confers enhancer blocking of the Fab-8 insulatorQ34166628
Parental imprinting in DrosophilaQ34213001
Imprinting along the Kcnq1 domain on mouse chromosome 7 involves repressive histone methylation and recruitment of Polycomb group complexes.Q34363546
Gardening the genome: DNA methylation in Arabidopsis thalianaQ34414767
Profiling epigenetic alterations in diseaseQ37882670
Non-coding transcripts in the H19 imprinting control region mediate gene silencing in transgenic DrosophilaQ38297213
Transcriptional repression by Drosophila and mammalian Polycomb group proteins in transfected mammalian cellsQ38310778
Control elements within the PWS/AS imprinting box and their function in the imprinting processQ40590108
Reinforcement of silencing at transposons and highly repeated sequences requires the concerted action of two distinct RNA polymerases IV in Arabidopsis.Q41807998
The transcriptional status but not the imprinting control region determines allele-specific histone modifications at the imprinted H19 locusQ41910878
Interaction between differentially methylated regions partitions the imprinted genes Igf2 and H19 into parent-specific chromatin loopsQ42632085
Higher-order structure in pericentric heterochromatin involves a distinct pattern of histone modification and an RNA componentQ43890842
Repeat-induced gene silencing in mammals.Q44031048
RNA polymerase IV functions in paramutation in Zea mays.Q45984611
Two regulatory genes of the maize anthocyanin pathway are homologous: isolation of B utilizing R genomic sequences.Q46598592
RNAi components are required for nuclear clustering of Polycomb group response elements.Q47072703
Mouse/human sequence divergence in a region with a paternal-specific methylation imprint at the human H19 locusQ48061527
Atypical RNA polymerase subunits required for RNA-directed DNA methylationQ48136173
Plant nuclear RNA polymerase IV mediates siRNA and DNA methylation-dependent heterochromatin formationQ48146967
A skeletal muscle-specific mouse Igf2 repressor lies 40 kb downstream of the geneQ48562987
Deletion of a silencer element disrupts H19 imprinting independently of a DNA methylation epigenetic switchQ48563204
Appropriate expression of the mouse H19 gene utilises three or more distinct enhancer regions spread over more than 130 kb.Q48563905
A paternal-specific methylation imprint marks the alleles of the mouse H19 geneQ49057890
A census of mammalian imprinting.Q34430259
Chromatin conversations: mechanisms and implications of paramutationQ34548805
The human HYMAI/PLAGL1 differentially methylated region acts as an imprint control region in miceQ34559930
An RNA-dependent RNA polymerase is required for paramutation in maizeQ34569244
The chromatin remodeling factor Bap55 functions through the TIP60 complex to regulate olfactory projection neuron dendrite targetingQ34573656
In the loop: long range chromatin interactions and gene regulationQ34580688
Rmr6 maintains meiotic inheritance of paramutant states in Zea maysQ34589702
Noncoding transcription by RNA polymerase Pol IVb/Pol V mediates transcriptional silencing of overlapping and adjacent genesQ34881670
Paramutation: the tip of an epigenetic iceberg?Q35108507
A transcriptional insulator at the imprinted H19/Igf2 locusQ35199693
Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2.Q35211749
Element 1360 and RNAi components contribute to HP1-dependent silencing of a pericentric reporterQ35239502
RNA at the steering wheelQ35605953
DNA methylation in insectsQ35729179
Differential chromatin structure within a tandem array 100 kb upstream of the maize b1 locus is associated with paramutationQ35780093
Analysis of the H19ICR insulatorQ35856849
Towards a mechanism for histone chaperonesQ35861914
Identification of a silencing element in the human 15q11-q13 imprinting center by using transgenic DrosophilaQ35884190
RNA meets chromatinQ36197886
DNA methylation and histone modifications: teaming up to silence genesQ36228564
CTCF is the master organizer of domain-wide allele-specific chromatin at the H19/Igf2 imprinted regionQ36421340
Genomic imprinting in the mealybugsQ36436510
The Prader-Willi/Angelman imprinted domain and its control centerQ36436601
Gene regulation by chromatin structure: paradigms established in Drosophila melanogasterQ36553584
Deeper into the maize: new insights into genomic imprinting in plantsQ36660578
RNA interference guides histone modification during the S phase of chromosomal replication.Q36692156
Noncoding RNAs and gene silencingQ36744484
Multiple imprinted sense and antisense transcripts, differential methylation and tandem repeats in a putative imprinting control region upstream of mouse Igf2.Q36820044
CTCF regulates allelic expression of Igf2 by orchestrating a promoter-polycomb repressive complex 2 intrachromosomal loopQ36959918
Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a.Q36967574
Epigenetic interplay between histone modifications and DNA methylation in gene silencingQ37137074
Roles of RNA polymerase IV in gene silencingQ37178200
Protein-binding elements establish in the oocyte the primary imprint of the Prader-Willi/Angelman syndromes domainQ37238842
Repeat elements and the Arabidopsis DNA methylation landscapeQ37749496
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P921main subjecttransgenic organismQ123738417
epigeneticsQ26939
P304page(s)689819
P577publication date2012-03-27
P1433published inGenetics Research InternationalQ26842364
P1476titleTransgenic epigenetics: using transgenic organisms to examine epigenetic phenomena
P478volume2012

Reverse relations

cites work (P2860)
Q52572069Abnormal development of floral meristem triggers defective morphogenesis of generative system in transgenic tomatoes.
Q52739602The maize b1 paramutation control region causes epigenetic silencing in Drosophila melanogaster.

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