Statins May Reduce Breast Cancer Risk, Particularly Hormone Receptor-Negative Disease

scientific article published in September 2009

Statins May Reduce Breast Cancer Risk, Particularly Hormone Receptor-Negative Disease is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/S12609-009-0021-5
P932PMC publication ID3335774
P698PubMed publication ID22540021
P5875ResearchGate publication ID224856336

P2093author name stringAllison W Kurian
Shaveta Vinayak
P2860cites workUse of statins and breast cancer: a meta-analysis of seven randomized clinical trials and nine observational studies.Q52994367
The association between 3-hydroxy-3-methylglutaryl conenzyme A inhibitor use and breast carcinoma risk among postmenopausal women: a case-control study.Q53368104
Short-term breast cancer prediction by random periareolar fine-needle aspiration cytology and the Gail risk model.Q53407386
Caveolin-1 inhibits breast cancer growth and metastasisQ57369965
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3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors and the risk of cancer: a nested case-control studyQ74116896
Differential modulation of caveolin-1 expression in cells of the vasculature by statinsQ75302836
Reduction of mouse mammary tumor formation and metastasis by lovastatin, an inhibitor of the mevalonate pathway of cholesterol synthesisQ77513498
Statin-induced breast cancer cell death: role of inducible nitric oxide and arginase-dependent pathwaysQ80726286
Chemoprevention of breast cancerQ80955303
Lovastatin-mediated G1 arrest is through inhibition of the proteasome, independent of hydroxymethyl glutaryl-CoA reductaseQ24645348
Osteoblast-derived Oxysterol Is a Migration-inducing Factor for Human Breast Cancer CellsQ28195859
MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trialQ28214393
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Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 StudyQ28283241
The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial investigatorsQ29547887
Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trialQ29617817
Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention StudyQ29617822
Prevention of Cardiovascular Events and Death with Pravastatin in Patients with Coronary Heart Disease and a Broad Range of Initial Cholesterol LevelsQ29620696
The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animalsQ33688733
Major outcomes in moderately hypercholesterolemic, hypertensive patients randomized to pravastatin vs usual care: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT-LLT).Q34164324
Statins and cancer risk: a meta-analysisQ34481478
Statins and risk of cancer: a systematic review and metaanalysisQ34585294
The statins as anticancer agentsQ35049816
Chemical, pharmacokinetic and pharmacodynamic properties of statins: an updateQ36014966
Statin use and breast cancer risk in a large population-based settingQ36120856
Breast-tissue sampling for risk assessment and preventionQ36157643
Statin use and breast cancer: prospective results from the Women's Health Initiative.Q36480676
Statin use and cancer risk in the General Practice Research DatabaseQ36694570
Translational approaches for the prevention of estrogen receptor-negative breast cancerQ36784148
Statins and cancer: A systematic review and meta-analysisQ37245345
Statins and breast cancer: may matrix metalloproteinase be the missing linkQ37393969
Race, breast cancer subtypes, and survival in the Carolina Breast Cancer StudyQ39605778
Simvastatin induces apoptosis in human breast cancer cells: p53 and estrogen receptor independent pathway requiring signalling through JNK.Q40204582
Breast cancer growth prevention by statinsQ40236401
Caveolin-1 gene disruption promotes mammary tumorigenesis and dramatically enhances lung metastasis in vivo. Role of Cav-1 in cell invasiveness and matrix metalloproteinase (MMP-2/9) secretionQ40517903
Cerivastatin, an inhibitor of HMG-CoA reductase, inhibits the signaling pathways involved in the invasiveness and metastatic properties of highly invasive breast cancer cell lines: an in vitro studyQ40790232
Inhibition of endothelial cell migration by cerivastatin, an HMG-CoA reductase inhibitor: contribution to its anti-angiogenic effectQ40808465
Caveolin 1 and Caveolin 2 are associated with breast cancer basal-like and triple-negative immunophenotype.Q40809878
Lovastatin mediated G1 arrest in normal and tumor breast cells is through inhibition of CDK2 activity and redistribution of p21 and p27, independent of p53.Q40995647
Cholesterol inhibition, cancer, and chemotherapyQ41089488
Lovastatin and tumor necrosis factor-alpha exhibit potentiated antitumor effects against Ha-ras-transformed murine tumor via inhibition of tumor-induced angiogenesisQ42816384
Differences in breast cancer hormone receptor status and histology by race and ethnicity among women 50 years of age and older.Q44052545
Estrogen receptor-negative breast cancer is less likely to arise among lipophilic statin usersQ44252782
Incidence of invasive breast cancer by hormone receptor status from 1992 to 1998.Q44265649
Effect of statins combined with estradiol on the proliferation of human receptor-positive and receptor-negative breast cancer cellsQ44507023
Mortality and incidence of cancer during 10-year follow-up of the Scandinavian Simvastatin Survival Study (4S).Q45036700
Serum lipids, lipid-lowering drugs, and the risk of breast cancerQ46772398
Statin use and risk of breast cancerQ46896215
P433issue3
P304page(s)148-156
P577publication date2009-09-01
P1433published inCurrent breast cancer reportsQ26842500
P1476titleStatins May Reduce Breast Cancer Risk, Particularly Hormone Receptor-Negative Disease
P478volume1

Reverse relations

cites work (P2860)
Q38522989Comorbidities and Their Management: Potential Impact on Breast Cancer Outcomes
Q34185642Lipophilic statin use and risk of breast cancer subtypes
Q38712771Racial differences in the effects of comorbidity on breast cancer-specific survival
Q57790350Statin use and risk of contralateral breast cancer: a nationwide cohort study
Q37137519The Effect of Atorvastatin on Breast Cancer Biomarkers in High-Risk Women

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