Discovery of blood transcriptomic markers for depression in animal models and pilot validation in subjects with early-onset major depression

scientific article published on 17 April 2012

Discovery of blood transcriptomic markers for depression in animal models and pilot validation in subjects with early-onset major depression is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/TP.2012.26
P932PMC publication ID3337072
P698PubMed publication ID22832901
P5875ResearchGate publication ID230568730

P2093author name stringE E Redei
G A Churchill
J Bridge
K Pajer
W Gardner
K Dennis
J Campo
A Lourie
B Strange
B M Andrus
K Blizinsky
P Vedell
P2860cites workThe metastasis-promoting phosphatase PRL-3 shows activity toward phosphoinositidesQ24318335
The cytoplasmic Purkinje onconeural antigen cdr2 down-regulates c-Myc function: implications for neuronal and tumor cell survivalQ24600187
Evaluating genetic markers and neurobiochemical analytes for fluoxetine response using a panel of mouse inbred strainsQ24632901
Three-dimensional solution structure of the extracellular region of the complement regulatory protein CD59, a new cell-surface protein domain related to snake venom neurotoxinsQ27729364
A comparison of normalization methods for high density oligonucleotide array data based on variance and biasQ27860710
Exploration, normalization, and summaries of high density oligonucleotide array probe level dataQ27861098
NIMH Diagnostic Interview Schedule for Children Version IV (NIMH DISC-IV): description, differences from previous versions, and reliability of some common diagnosesQ28142796
The endophenotype concept in psychiatry: etymology and strategic intentionsQ28187744
SynCAM, a synaptic adhesion molecule that drives synapse assemblyQ28219424
Gene expression profiling of the effects of castration and estrogen treatment in the rat uterusQ28571133
Genome-wide association study of recurrent early-onset major depressive disorderQ28943558
affy--analysis of Affymetrix GeneChip data at the probe levelQ29547353
Using ANOVA to analyze microarray dataQ30955035
Plasma protein biomarkers for depression and schizophrenia by multi analyte profiling of case-control collectionsQ30977897
beadarray: R classes and methods for Illumina bead-based data.Q31116642
Huntingtin interacts with the cue domain of gp78 and inhibits gp78 binding to ubiquitin and p97/VCP.Q33529116
Biomarkers in psychiatry: drawbacks and potential for misuseQ33647114
Novel animal models of affective disordersQ34137324
Peripheral profiling analysis for bipolar disorder reveals markers associated with reduced cell survival.Q34156394
A specific laboratory test for the diagnosis of melancholia. Standardization, validation, and clinical utilityQ71465909
Deficiency of complement defense protein CD59 may contribute to neurodegeneration in Alzheimer's diseaseQ73066482
Expression of complement regulators and receptors on human NT2-N neurons--effect of hypoxia and reoxygenationQ79372112
Toll-like receptors 7 and 8 expression is associated with poor outcome and greater inflammatory response in acute ischemic strokeQ83483578
Mood disorders in children and adolescents: an epidemiologic perspectiveQ34295954
Clinical response and risk for reported suicidal ideation and suicide attempts in pediatric antidepressant treatment: a meta-analysis of randomized controlled trialsQ34619977
Brain-derived neurotrophic factor as a biomarker for mood disorders: an historical overview and future directions.Q34621808
Adult outcomes of childhood and adolescent depression. I. Psychiatric statusQ34631711
Subtractive hybridisation screen identifies genes regulated by glucose deprivation in human neuroblastoma cellsQ34667361
Gene expression patterns in the hippocampus and amygdala of endogenous depression and chronic stress models.Q35051148
Lpd depletion reveals that SRF specifies radial versus tangential migration of pyramidal neurons.Q35146088
Functional biomarkers of depression: diagnosis, treatment, and pathophysiologyQ35356872
Depletion of GGA3 stabilizes BACE and enhances beta-secretase activityQ35985945
Health outcomes related to early adolescent depressionQ36082631
Major depressive disorder in children and adolescents: clinical trial design and antidepressant efficacy.Q36241597
Switching to another SSRI or to venlafaxine with or without cognitive behavioral therapy for adolescents with SSRI-resistant depression: the TORDIA randomized controlled trialQ36514240
Sex- and lineage-specific inheritance of depression-like behavior in the ratQ37150452
Glutathione dysregulation and the etiology and progression of human diseases.Q37372896
Two different putative genetic animal models of childhood depression--a reviewQ37527231
The adolescent child health and illness profile. A population-based measure of health.Q39261209
Targeting neural-restrictive silencer factor sensitizes tumor cells to antibody-based cancer immunotherapy in vitro via multiple mechanismsQ39710538
Gp78, an ER associated E3, promotes SOD1 and ataxin-3 degradation.Q39815864
Fever, sickness behavior, and expression of inflammatory genes in the hypothalamus after systemic and localized subcutaneous stimulation of rats with the Toll-like receptor 7 agonist imiquimodQ40304789
Selectively bred Wistar–Kyoto rats: an animal model of depression and hyper-responsiveness to antidepressantsQ42612289
Phenomic, convergent functional genomic, and biomarker studies in a stress-reactive genetic animal model of bipolar disorder and co-morbid alcoholismQ43459376
Identification of blood biomarkers for psychosis using convergent functional genomics.Q43616392
Altered hormone levels and circadian rhythm of activity in the WKY rat, a putative animal model of depressionQ43708466
Amplified behavioral and endocrine responses to forced swim stress in the Wistar-Kyoto rat.Q43871097
Clinical indices of familial depression in the Swedish Twin RegistryQ44927127
Psychiatric endophenotypes and the development of valid animal models.Q45920656
Strain differences in hypothalamic-pituitary-adrenal activity and stress ulcerQ48182735
Identification, expression and tissue distribution of cytidine 5'-monophosphate N-acetylneuraminic acid synthetase activity in the rat.Q48473840
Multiple sclerosis: in situ evidence for antibody- and complement-mediated demyelinationQ48489118
Assessment of a multi-assay, serum-based biological diagnostic test for major depressive disorder: a pilot and replication studyQ48787872
Ascorbic acid treatment, similarly to fluoxetine, reverses depressive-like behavior and brain oxidative damage induced by chronic unpredictable stressQ48788833
Unipolar depression in adolescents: clinical outcome in adulthoodQ48820908
Glutamate cysteine ligase (GCL) and self reported depression: an association study from the HUNT.Q48922098
Impairment of social and emotional behaviors in Cadm1-knockout miceQ50303923
Mutations in the gene encoding CADM1 are associated with autism spectrum disorderQ50345265
Natural course of adolescent major depressive disorder: I. Continuity into young adulthoodQ50637471
Gene expression signature in peripheral blood cells from medical students exposed to chronic psychological stress.Q50889532
Development of depression from preadolescence to young adulthood: emerging gender differences in a 10-year longitudinal studyQ50902337
Psychosocial functioning of young adults who have experienced and recovered from major depressive disorder during adolescence.Q51947062
Depressive symptoms in adolescence as predictors of early adulthood depressive disorders and maladjustment.Q51955710
Criterion validity of the NIMH Diagnostic Interview Schedule for Children Version 2.3 (DISC-2.3).Q52302702
Depressed Adolescents Grown UpQ57150621
Performance of a new pubertal self-assessment questionnaire: a preliminary studyQ57416367
P921main subjecttranscriptomeQ252857
P304page(s)e101
P577publication date2012-04-17
P1433published inTranslational PsychiatryQ15716636
P1476titleDiscovery of blood transcriptomic markers for depression in animal models and pilot validation in subjects with early-onset major depression
P478volume2

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cites work (P2860)
Q26786354A Review of Biomarkers in Mood and Psychotic Disorders: A Dissection of Clinical vs. Preclinical Correlates
Q37622651A support vector machine model provides an accurate transcript-level-based diagnostic for major depressive disorder
Q42162079An instant diagnosis for depression by blood test
Q50245086Are Expectations the Missing Link between Life History Strategies and Psychopathology?
Q34096263Attenuated inhibition of medium spiny neurons participates in the pathogenesis of childhood depression.
Q58898997Biomarker discovery
Q28389366Biomarkers in pediatric depression
Q35939562Blood Transcriptomic Markers in Patients with Late-Onset Major Depressive Disorder
Q45867306Blood genome-wide transcriptional profiles reflect broad molecular impairments and strong blood-brain links in Alzheimer's disease
Q34345609Blood transcriptomic biomarkers in adult primary care patients with major depressive disorder undergoing cognitive behavioral therapy.
Q48087014Blood transcriptomic markers for major depression: from animal models to clinical settings
Q38219783Blood-based biomarkers in depression: emerging themes in clinical research
Q47555879Blood-based biomarkers predicting response to antidepressants.
Q57461574Connective Tissue Growth Factor Is a Novel Prodepressant
Q34958642Core modular blood and brain biomarkers in social defeat mouse model for post traumatic stress disorder
Q41660620Critical Roles of Dual-Specificity Phosphatases in Neuronal Proteostasis and Neurological Diseases.
Q26741418Epigenetic Modifications of Major Depressive Disorder
Q34947645Gene expression profiles in relation to tension and dissociation in borderline personality disorder
Q38154917Gene expression: biomarker of antidepressant therapy?
Q30654005Genome-wide methylation study on depression: differential methylation and variable methylation in monozygotic twins
Q38611730Heterogeneous stock rats: a model to study the genetics of despair-like behavior in adolescence.
Q33780372Identification of commonly altered genes between in major depressive disorder and a mouse model of depression
Q26775316Innate and adaptive immunity in the development of depression: An update on current knowledge and technological advances
Q34113404Investigation of manic and euthymic episodes identifies state- and trait-specific gene expression and STAB1 as a new candidate gene for bipolar disorder
Q26852637Mass spectrometry for the detection of potential psychiatric biomarkers
Q31153904Monitoring candidate gene expression variations before, during and after a first major depressive episode in a 51-year-old man.
Q27339187Nature and nurture: environmental influences on a genetic rat model of depression
Q37176590Peripheral biomarkers in animal models of major depressive disorder
Q50166798Prenatal substance exposure and offspring development: Does DNA methylation play a role?
Q35558095Reduced default mode network suppression during a working memory task in remitted major depression
Q36591265Responder and nonresponder patients exhibit different peripheral transcriptional signatures during major depressive episode
Q48048867Seeking an objective diagnosis of depression
Q38630683Talking the talk, but not walking the walk: RT-qPCR as a paradigm for the lack of reproducibility in molecular research
Q34906947Testing the predictive value of peripheral gene expression for nonremission following citalopram treatment for major depression
Q36635056The epigenetics of maternal cigarette smoking during pregnancy and effects on child development.
Q36314812The genetics of alcohol dependence: advancing towards systems-based approaches
Q49214098The impact of age of onset on amygdala intrinsic connectivity in major depression
Q38084866The long-term impact of early adversity on late-life psychiatric disorders
Q38529746The promise of biomarkers in diagnosing major depression in primary care: the present and future
Q38193006The search for peripheral biomarkers for major depression: benefiting from successes in the biology of smoking
Q38604950Translational Identification of Transcriptional Signatures of Major Depression and Antidepressant Response.
Q38370696Translational psychiatry--light at the end of the tunnel.
Q35109175Using biomarkers to predict treatment response in major depressive disorder: evidence from past and present studies
Q61801086What do DNA methylation studies tell us about depression? A systematic review
Q85823839[Endophenotypes: the molecular biology point of view]

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