Establishment of a Refined Oral Glucose Tolerance Test in Pigs, and Assessment of Insulin, Glucagon and Glucagon-Like Peptide-1 Responses

scientific article published on 9 February 2016

Establishment of a Refined Oral Glucose Tolerance Test in Pigs, and Assessment of Insulin, Glucagon and Glucagon-Like Peptide-1 Responses is …
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P819ADS bibcode2016PLoSO..1148896M
P356DOI10.1371/JOURNAL.PONE.0148896
P8608Fatcat IDrelease_cbsei2tjmrd5fesxxfmppkvv64
P932PMC publication ID4747562
P698PubMed publication ID26859145
P5875ResearchGate publication ID293797060

P50authorElin ManellQ59692394
P2093author name stringAnna Svensson
Marianne Jensen-Waern
Patricia Hedenqvist
P2860cites workEffect of pectin on gastric emptying and gastroduodenal motility in normal subjectsQ68922811
Stimulation of insulin secretion by gastric inhibitory polypeptide in manQ69602585
The intravenous glucose tolerance test in the pigQ70813598
Glucose-dependent insulinotropic polypeptide gene expression in the stomach: revealed by a transgenic mouse study, in situ hybridization and immunohistochemical stainingQ73049295
PLASMA INSULIN RESPONSE TO ORAL AND INTRAVENOUS GLUCOSE ADMINISTRATIONQ77059466
Insulin treatment of streptozotocin-induced diabetes re-establishes the patterns in carbohydrate, fat and amino acid metabolisms in growing pigsQ87192085
Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational studyQ24652963
Valine pyrrolidide preserves intact glucose-dependent insulinotropic peptide and improves abnormal glucose tolerance in minipigs with reduced beta-cell massQ24655898
The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research GroupQ27861088
Estimated life expectancy in a Scottish cohort with type 1 diabetes, 2008-2010Q28254978
Glucose-dependent insulinotropic peptide (GIP) gene expression in the rat salivary glandQ28575654
Biology of incretins: GLP-1 and GIPQ29617302
Emergence of type 2 diabetes mellitus in children: epidemiological evidenceQ34153728
Associations of diabetes mellitus with total life expectancy and life expectancy with and without cardiovascular diseaseQ34636629
Prevalence of type 1 and type 2 diabetes among children and adolescents from 2001 to 2009.Q35203692
Age before stage: insulin resistance rises before the onset of puberty: a 9-year longitudinal study (EarlyBird 26).Q35879096
Fasting serum insulin levels in childhoodQ36061510
Physiologic evaluation of factors controlling glucose tolerance in man: measurement of insulin sensitivity and beta-cell glucose sensitivity from the response to intravenous glucoseQ37006231
Possible role of GLP-1 and its agonists in the treatment of type 1 diabetes mellitusQ38024321
Potential role of non-insulin adjunct therapy in Type 1 diabetes.Q38026900
Chronic kidney disease and cardiovascular risk: epidemiology, mechanisms, and preventionQ38111136
Glucose-dependent insulinotropic polypeptide: a bifunctional glucose-dependent regulator of glucagon and insulin secretion in humansQ39221120
Glucose intolerance and reduced proliferation of pancreatic beta-cells in transgenic pigs with impaired glucose-dependent insulinotropic polypeptide functionQ40132400
Glucagon suppression during OGTT worsens while suppression during IVGTT sustains alongside development of glucose intolerance in patients with chronic pancreatitis.Q43007440
Inappropriate glucagon response after oral compared with isoglycemic intravenous glucose administration in patients with type 1 diabetesQ43183447
Glucagon-like peptide-1 7-36: a physiological incretin in man.Q43623564
Impaired beta-cell function, incretin effect, and glucagon suppression in patients with type 1 diabetes who have normal fasting glucoseQ43935399
Assessing the shape of the glucose curve during an oral glucose tolerance testQ44381333
Glucose-dependent insulinotropic polypeptide and insulin-like immunoreactivity in saliva following sham-fed and swallowed mealsQ44457557
Beta-cell function and insulin sensitivity contribute to the shape of plasma glucose curve during an oral glucose tolerance test in non-diabetic individualsQ46457323
Expression of glucose-dependent insulinotropic polypeptide and its receptor in the rat major salivary glandsQ46814718
Percentiles of fasting serum insulin, glucose, HbA1c and HOMA-IR in pre-pubertal normal weight European children from the IDEFICS cohortQ47426799
Response of incretins (GIP and GLP-1) to an oral glucose load in female and male subjects with normal glucose tolerance.Q51109897
Impaired regulation of the incretin effect in patients with type 2 diabetes.Q51381300
Reduced postprandial concentrations of intact biologically active glucagon-like peptide 1 in type 2 diabetic patients.Q51550359
Dietary guar gum effects on postprandial blood glucose, insulin and hydroxyproline in humans.Q51618366
The Shape of the Plasma Glucose Curve During an Oral Glucose Tolerance Test as an Indicator of Beta Cell Function and Insulin Sensitivity in End-Pubertal Obese GirlsQ55409131
Dietary fibres, fibre analogues, and glucose tolerance: importance of viscosityQ56095509
GLP-1 Response to Oral Glucose Is Reduced in Prediabetes, Screen-Detected Type 2 Diabetes, and Obesity and Influenced by Sex: The ADDITION-PRO StudyQ57655878
Glucagon responses to increasing oral loads of glucose and corresponding isoglycaemic intravenous glucose infusions in patients with type 2 diabetes and healthy individualsQ58447633
Suppression of glucagon secretion is lower after oral glucose administration than during intravenous glucose administration in human subjectsQ58448416
Glucagon-like peptide 1 undergoes differential tissue-specific metabolism in the anesthetized pigQ58449056
Reduced incretin effect in type 2 (non-insulin-dependent) diabetesQ68865252
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectglucagonQ28163629
P304page(s)e0148896
P577publication date2016-02-09
P1433published inPLOS OneQ564954
P1476titleEstablishment of a Refined Oral Glucose Tolerance Test in Pigs, and Assessment of Insulin, Glucagon and Glucagon-Like Peptide-1 Responses
P478volume11

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cites work (P2860)
Q47248440Anaesthesia and changes in parameters that reflect glucose metabolism in pigs - a pilot study
Q90706527In Vivo Effects of Einkorn Wheat (Triticum monococcum) Bread on the Intestinal Microbiota, Metabolome, and on the Glycemic and Insulinemic Response in the Pig Model
Q98463604Intraperitoneal and subcutaneous glucagon delivery in anaesthetized pigs: effects on circulating glucagon and glucose levels
Q52679538Male grower pigs fed cereal soluble dietary fibres display biphasic glucose response and delayed glycaemic response after an oral glucose tolerance test.
Q55263354Mother's obesity and high child's waist circumference are predictive factors of severe child's obesity: an observational study in French Guiana.
Q96682403Supplying sows energy on the expected day of farrowing improves farrowing kinetics and newborn piglet performance in the first 24 h after birth

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