| review article | Q7318358 |
| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1040297710 |
| P356 | DOI | 10.1023/B:REMD.0000045103.00467.9A |
| P698 | PubMed publication ID | 15486464 |
| P50 | author | Folkert Kuipers | Q53606987 |
| Bart Staels | Q28360345 | ||
| P2093 | author name string | Folkert Kuipers | |
| Ekkehard Sturm | |||
| Thierry Claudel | |||
| P2860 | cites work | Identification of a novel gene family encoding human liver-specific organic anion transporter LST-1 | Q22009932 |
| Identification of a nuclear receptor for bile acids | Q22010058 | ||
| Bile acids: natural ligands for an orphan nuclear receptor | Q22010063 | ||
| Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors | Q24290397 | ||
| Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis | Q24305561 | ||
| Identification of farnesoid X receptor beta as a novel mammalian nuclear receptor sensing lanosterol | Q24540997 | ||
| Functional expression cloning and characterization of the hepatocyte Na+/bile acid cotransport system | Q24559977 | ||
| Comparison of complete nuclear receptor sets from the human, Caenorhabditis elegans and Drosophila genomes | Q24803733 | ||
| A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR | Q27641086 | ||
| Structural basis for bile acid binding and activation of the nuclear receptor FXR | Q27641089 | ||
| Hepatocanalicular bile salt export pump deficiency in patients with progressive familial intrahepatic cholestasis | Q28139039 | ||
| Correlation of farnesoid X receptor coactivator recruitment and cholesterol 7alpha-hydroxylase gene repression by bile acids | Q28141468 | ||
| FXR induces the UGT2B4 enzyme in hepatocytes: a potential mechanism of negative feedback control of FXR activity | Q28179104 | ||
| Farnesoid X receptor agonists suppress hepatic apolipoprotein CIII expression | Q28191058 | ||
| Endogenous bile acids are ligands for the nuclear receptor FXR/BAR | Q28198990 | ||
| The enzymes, regulation, and genetics of bile acid synthesis | Q28204726 | ||
| Farnesoid X receptor and bile salts are involved in transcriptional regulation of the gene encoding the human bile salt export pump | Q43899918 | ||
| Identification of gene-selective modulators of the bile acid receptor FXR. | Q44259003 | ||
| Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane | Q44527593 | ||
| Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice | Q44569549 | ||
| Role of nuclear bile acid receptor, FXR, in adaptive ABC transporter regulation by cholic and ursodeoxycholic acid in mouse liver, kidney and intestine | Q44583396 | ||
| Purification and characterization of cholyl-CoA: taurine N-acetyltransferase from the liver of domestic fowl (Gallus gallus) | Q44695916 | ||
| Expression cloning and characterization of the hamster ileal sodium-dependent bile acid transporter. | Q48085781 | ||
| Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis. | Q52541251 | ||
| The synthesis of taurocholic and glycocholic acids by preparations of human liver. II. An analysis of the stimulating effect of the L fraction. | Q53680056 | ||
| Hepatobiliary transporter expression in percutaneous liver biopsies of patients with cholestatic liver diseases. | Q54017726 | ||
| Molecular pathogenesis of cholestasis. | Q54344101 | ||
| Bile acid sulfotransferase I from rat liver sulfates bile acids and 3-hydroxy steroids: purification, N-terminal amino acid sequence, and kinetic properties. | Q55059826 | ||
| Cytokines tumor necrosis factor and interleukin-6 in experimental biliary obstruction in mice | Q68134831 | ||
| In situ localization of the hepatocytic Na+/Taurocholate cotransporting polypeptide in rat liver | Q72800609 | ||
| Hepatic basolateral sodium-dependent-bile acid transporter expression in two unusual cases of hypercholanemia and in extrahepatic biliary atresia | Q73319943 | ||
| Farnesoid X receptor responds to bile acids and represses cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription | Q73643139 | ||
| Molecular mechanisms of cholestasis: causes and consequences of impaired bile formation | Q77451209 | ||
| Farnesoid X Receptor Regulates Bile Acid-Amino Acid Conjugation | Q28204827 | ||
| The amino acid residues asparagine 354 and isoleucine 372 of human farnesoid X receptor confer the receptor with high sensitivity to chenodeoxycholate | Q28217144 | ||
| Identification of a nuclear receptor that is activated by farnesol metabolites | Q28302684 | ||
| Liver receptor homologue-1 mediates species- and cell line-specific bile acid-dependent negative feedback regulation of the apical sodium-dependent bile acid transporter | Q28513496 | ||
| Dehydroepiandrosterone sulfotransferase gene induction by bile acid activated farnesoid X receptor | Q28570159 | ||
| The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver | Q28571688 | ||
| Elevated cholesterol metabolism and bile acid synthesis in mice lacking membrane tyrosine kinase receptor FGFR4 | Q28590891 | ||
| Enterohepatic circulation of bile salts in farnesoid X receptor-deficient mice: efficient intestinal bile salt absorption in the absence of ileal bile acid-binding protein | Q28593082 | ||
| A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis | Q29617241 | ||
| Identification of a chemical tool for the orphan nuclear receptor FXR. | Q31431724 | ||
| Nuclear receptor regulation of cholesterol and bile acid metabolism. | Q33796274 | ||
| Identification of a bile acid-responsive element in the human ileal bile acid-binding protein gene. Involvement of the farnesoid X receptor/9-cis-retinoic acid receptor heterodimer | Q33876356 | ||
| Intracellular transport of bile acids | Q33944790 | ||
| Transcriptional regulation of the human sterol 12alpha-hydroxylase gene (CYP8B1): roles of heaptocyte nuclear factor 4alpha in mediating bile acid repression | Q34089245 | ||
| Targeted inactivation of sister of P-glycoprotein gene (spgp) in mice results in nonprogressive but persistent intrahepatic cholestasis | Q34118792 | ||
| 6alpha-ethyl-chenodeoxycholic acid (6-ECDCA), a potent and selective FXR agonist endowed with anticholestatic activity. | Q34143282 | ||
| Ursodeoxycholic acid in cholestatic liver disease: mechanisms of action and therapeutic use revisited | Q34146325 | ||
| Glucuronidation of hyodeoxycholic acid in human liver. Evidence for a selective role of UDP-glucuronosyltransferase 2B4. | Q34345008 | ||
| Genes and cholestasis. | Q34455645 | ||
| Bile acid-activated nuclear receptor FXR suppresses apolipoprotein A-I transcription via a negative FXR response element | Q34790389 | ||
| Bile acid regulation of hepatic physiology: III. Bile acids and nuclear receptors | Q35063226 | ||
| Identification of the bile acid binding proteins in human serum by photoaffinity labeling | Q36690966 | ||
| Alternative splicing of the rat sodium/bile acid transporter changes its cellular localization and transport properties | Q37273791 | ||
| Rat cholangiocytes absorb bile acids at their apical domain via the ileal sodium-dependent bile acid transporter | Q37375465 | ||
| Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor. | Q38300264 | ||
| Hepatoprotection by the farnesoid X receptor agonist GW4064 in rat models of intra- and extrahepatic cholestasis | Q40271507 | ||
| Retinoid X receptor (RXR) agonist-induced antagonism of farnesoid X receptor (FXR) activity due to absence of coactivator recruitment and decreased DNA binding | Q40678679 | ||
| Natural structural variants of the nuclear receptor farnesoid X receptor affect transcriptional activation | Q40694910 | ||
| Bile acid induction of cytokine expression by macrophages correlates with repression of hepatic cholesterol 7alpha-hydroxylase | Q41737442 | ||
| Enhanced expression of the human multidrug resistance protein 3 by bile salt in human enterocytes. A transcriptional control of a plausible bile acid transporter | Q42511033 | ||
| 12 alpha-hydroxylase activity in human liver and its relation to cholesterol 7 alpha-hydroxylase activity | Q43410713 | ||
| Down-regulation of cholesterol 7alpha-hydroxylase (CYP7A1) gene expression by bile acids in primary rat hepatocytes is mediated by the c-Jun N-terminal kinase pathway | Q43559873 | ||
| Cellular localization and up-regulation of multidrug resistance-associated protein 3 in hepatocytes and cholangiocytes during obstructive cholestasis in rat liver | Q43563069 | ||
| The orphan nuclear receptor, shp, mediates bile acid-induced inhibition of the rat bile acid transporter, ntcp | Q43662706 | ||
| Effects of ursodeoxycholic and cholic acid feeding on hepatocellular transporter expression in mouse liver | Q43662715 | ||
| Farnesoid X-activated receptor induces apolipoprotein C-II transcription: a molecular mechanism linking plasma triglyceride levels to bile acids | Q43752389 | ||
| P433 | issue | 4 | |
| P304 | page(s) | 319-326 | |
| P577 | publication date | 2004-12-01 | |
| P1433 | published in | Reviews in Endocrine and Metabolic Disorders | Q15766899 |
| P1476 | title | The Farnesoid X Receptor (FXR) as modulator of bile acid metabolism | |
| P478 | volume | 5 |
| Q55843627 | A novel heterozygous NR1H4 termination codon mutation in idiopathic infantile cholestasis |
| Q34509231 | AKR1B7 is induced by the farnesoid X receptor and metabolizes bile acids |
| Q41964052 | An increased flux through the glucose 6-phosphate pool in enterocytes delays glucose absorption in Fxr-/- mice |
| Q89964111 | Baicalin Protects Against 17α-Ethinylestradiol-Induced Cholestasis via the Sirtuin 1/Hepatic Nuclear Receptor-1α/Farnesoid X Receptor Pathway |
| Q28085493 | Bile acid nuclear receptor FXR and digestive system diseases |
| Q43057268 | Bile acids increase hepatitis B virus gene expression and inhibit interferon-alpha activity |
| Q49722254 | Current therapies in alleviating liver disorders and cancers with a special focus on the potential of vitamin D. |
| Q34535765 | Effects of bile acids and the bile acid receptor FXR agonist on the respiratory rhythm in the in vitro brainstem medulla slice of neonatal Sprague-Dawley rats |
| Q46605391 | Exercising the nuclear option to treat cholestasis: CAR and PXR ligands |
| Q46897927 | FXR-mediated regulation of angiotensin type 2 receptor expression in vascular smooth muscle cells |
| Q90034560 | Gut microbiota and inflammation in chronic kidney disease and their roles in the development of cardiovascular disease |
| Q53259885 | Hepatology over the years. |
| Q59335763 | Hypothalamus-Pituitary-Adrenal Dysfunction in Cholestatic Liver Disease |
| Q37199631 | Mechanisms of disease: Inborn errors of bile acid synthesis |
| Q36060817 | Morphologic Damage of Rat Alveolar Epithelial Type II Cells Induced by Bile Acids Could Be Ameliorated by Farnesoid X Receptor Inhibitor Z-Guggulsterone In Vitro |
| Q64230670 | Nuclear Receptors in the Pathogenesis and Management of Inflammatory Bowel Disease |
| Q28390150 | Nutritional lipidomics: molecular metabolism, analytics, and diagnostics |
| Q42696407 | Pyrazinamide Induced Rat Cholestatic Liver Injury through Inhibition of FXR Regulatory Effect on Bile Acid Synthesis and Transport |
| Q46132296 | The farnesoid X receptor (FXR) as a new target in non-alcoholic steatohepatitis |
| Q28587753 | The farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in mice |
| Q28118770 | The nuclear receptor FXR is expressed in pancreatic beta-cells and protects human islets from lipotoxicity |
| Q39943758 | Transactivation of the hepatitis B virus core promoter by the nuclear receptor FXRalpha |
| Q38323598 | Transient impairment of the adaptive response to fasting in FXR-deficient mice |
| Q33236324 | Transport of fluorescent chenodeoxycholic acid via the human organic anion transporters OATP1B1 and OATP1B3. |
| Q39642788 | Upregulation of scavenger receptor class B type I expression by activation of FXR in hepatocyte |
Search more.