Nanoparticle-mediated p53 gene therapy for tumor inhibition

scientific article published in February 2011

Nanoparticle-mediated p53 gene therapy for tumor inhibition is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/S13346-010-0008-9
P932PMC publication ID3339849
P698PubMed publication ID22553503
P5875ResearchGate publication ID224889227

P2093author name stringVinod Labhasetwar
Wenxue Ma
Jayanth Panyam
Blanka Sharma
Sanja Dimitrijevic
Isaac Morris Adjei
P2860cites workTumor suppressor activity of RB and p53 genes in human breast carcinoma cellsQ70545069
TP53 gene mutations in prostate cancer progressionQ84510020
Surfing the p53 networkQ28032484
Live or let die: the cell's response to p53Q29547663
p53-dependent apoptosis modulates the cytotoxicity of anticancer agentsQ29615031
Transcriptional control of human p53-regulated genesQ29617650
Cancer stem cells: models and conceptsQ29620611
Non-viral gene delivery using nanoparticles.Q30381073
Germline mutations and polymorphisms in the origins of cancers in womenQ33606675
Optical Imaging and Magnetic Field Targeting of Magnetic Nanoparticles in TumorsQ34164158
Tumor-targeted p53-gene therapy enhances the efficacy of conventional chemo/radiotherapyQ34328569
Awakening guardian angels: drugging the p53 pathwayQ35014385
Restoration of wild-type p53 function in human cancer: relevance for tumor therapy.Q36710840
Recent advances in p53 research: an interdisciplinary perspective.Q37273304
Viral vectors for gene transfer: current status of gene therapeuticsQ37706296
Receptor-targeted nanocarriers for therapeutic delivery to cancerQ37804383
Adenoviral-mediated p53 gene transfer to non-small cell lung cancer through endobronchial injectionQ39425663
Cancer progression and p53.Q40369102
Nanoparticle-mediated wild-type p53 gene delivery results in sustained antiproliferative activity in breast cancer cellsQ40404364
Rapid endo-lysosomal escape of poly(DL-lactide-co-glycolide) nanoparticles: implications for drug and gene deliveryQ40713744
Parenteral gene therapy with p53 inhibits human breast tumors in vivo through a bystander mechanism without evidence of toxicityQ41133661
Systemic gene delivery expands the repertoire of effective antiangiogenic agentsQ41649129
Inhibiting tumor growth by targeting tumor vasculature with galectin-1 antagonist anginex conjugated to the cytotoxic acylfulvene, 6-hydroxylpropylacylfulveneQ43215992
Regulation of cancer stem cells by p53.Q43249111
Targeting of tumor endothelium by RGD-grafted PLGA-nanoparticles loaded with paclitaxelQ43287891
p53 and PTEN/MMAC1/TEP1 gene therapy of human prostate PC-3 carcinoma xenograft, using transferrin-facilitated lipofection gene delivery strategyQ43950150
Dynamics of endocytosis and exocytosis of poly(D,L-lactide-co-glycolide) nanoparticles in vascular smooth muscle cellsQ44361209
Critical determinants in PLGA/PLA nanoparticle-mediated gene expressionQ44403133
A nonreplicating adenoviral vector that contains the wild-type p53 transgene combined with chemotherapy for primary breast cancer: safety, efficacy, and biologic activity of a novel gene-therapy approachQ45861413
Evidence that transfer of functional p53 protein results in increased apoptosis in prostate cancerQ45874850
Adenovirus-mediated wild-type p53 gene transfer down-regulates vascular endothelial growth factor expression and inhibits angiogenesis in human colon cancerQ45887756
Phase I study of repeated intraepithelial delivery of adenoviral p53 in patients with dysplastic oral leukoplakiaQ47990319
The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells.Q53370119
A DNA controlled-release coating for gene transfer: transfection in skeletal and cardiac muscle.Q53942787
P433issue1
P921main subjectnanoparticleQ61231
gene therapyQ213901
P304page(s)43-52
P577publication date2011-02-01
P1433published inDrug delivery and translational researchQ27723621
P1476titleNanoparticle-mediated p53 gene therapy for tumor inhibition
P478volume1

Reverse relations

cites work (P2860)
Q37298541Applications of nanoparticles in the detection and treatment of kidney diseases
Q38819542Attenuated Total Reflectance Fourier Transform Infrared Spectroscopy: An analytical technique to understand therapeutic responses at the molecular level.
Q91610685Gene Therapy Today and Tomorrow
Q37445335Heterogeneity in nanoparticles influences biodistribution and targeting
Q36105141Inhibition of tumor angiogenesis and growth by nanoparticle-mediated p53 gene therapy in mice
Q88432409Nanoparticle Properties for Delivery to Cartilage: The Implications of Disease State, Synovial Fluid, and Off-Target Uptake
Q64981473Nonviral Gene Therapy for Cancer: A Review.
Q45864098PTEN and TRAIL genes loaded zein nanoparticles as potential therapy for hepatocellular carcinoma
Q36759358Poly(β-amino ester) nanoparticle delivery of TP53 has activity against small cell lung cancer in vitro and in vivo
Q36893395Selective biophysical interactions of surface modified nanoparticles with cancer cell lipids improve tumor targeting and gene therapy
Q57492228Targeted nonviral gene therapy in prostate cancer