Direct Observation of Translocation in Individual DNA Polymerase Complexes

scientific article published on February 29, 2012

Direct Observation of Translocation in Individual DNA Polymerase Complexes is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.M111.338418
P953full work available online athttp://www.jbc.org/content/287/16/13407.full.pdf
https://api.elsevier.com/content/article/PII:S0021925820530779?httpAccept=text/plain
https://api.elsevier.com/content/article/PII:S0021925820530779?httpAccept=text/xml
https://doi.org/10.1074/jbc.m111.338418
https://europepmc.org/articles/PMC3339981
https://europepmc.org/articles/PMC3339981?pdf=render
https://syndication.highwire.org/content/doi/10.1074/jbc.M111.338418
P932PMC publication ID3339981
P698PubMed publication ID22378784

P2093author name stringHongyun Wang
Gerald M. Cherf
Andre Marziali
Mark Akeson
Kate R. Lieberman
Joseph M. Dahl
Daniel R. Garalde
Nahid N. Jetha
Ai H. Mai
P2860cites workPrimer-terminus stabilization at the 3'-5' exonuclease active site of phi29 DNA polymerase. Involvement of two amino acid residues highly conserved in proofreading DNA polymerasesQ24563201
Structures of phi29 DNA polymerase complexed with substrate: the mechanism of translocation in B-family polymerasesQ24684192
Structure of the replicating complex of a pol alpha family DNA polymeraseQ27632340
Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutationsQ27640744
Phosphonoformic Acid Inhibits Viral Replication by Trapping the Closed Form of the DNA PolymeraseQ27667828
Crystal structures of the Klenow fragment of DNA polymerase I complexed with deoxynucleoside triphosphate and pyrophosphateQ27731499
Structure of Taq polymerase with DNA at the polymerase active siteQ27733244
Crystal Structure of a pol α Family Replication DNA Polymerase from Bacteriophage RB69Q27740210
Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 Å resolutionQ27748814
The bacteriophage ϕ29 DNA polymeraseQ29028718
How DNA travels between the separate polymerase and 3'-5'-exonuclease sites of DNA polymerase I (Klenow fragment).Q30381702
Conformational transitions in DNA polymerase I revealed by single-molecule FRET.Q33640344
Processive proofreading and the spatial relationship between polymerase and exonuclease active sites of bacteriophage phi29 DNA polymerase.Q33874711
Insights into strand displacement and processivity from the crystal structure of the protein-primed DNA polymerase of bacteriophage phi29.Q34368233
Relating structure to function in phi29 DNA polymeraseQ34377993
Processive replication of single DNA molecules in a nanopore catalyzed by phi29 DNA polymeraseQ34789206
Distinct Complexes of DNA Polymerase I (Klenow Fragment) for Base and Sugar Discrimination during Nucleotide Substrate SelectionQ34800371
Identification of a transient excision intermediate at the crossroads between DNA polymerase extension and proofreading pathwaysQ36002542
Fluorescence of 2-aminopurine reveals rapid conformational changes in the RB69 DNA polymerase-primer/template complexes upon binding and incorporation of matched deoxynucleoside triphosphatesQ36168687
Sequence-specific detection of individual DNA polymerase complexes in real time using a nanoporeQ36828756
Replication of individual DNA molecules under electronic control using a protein nanoporeQ37014345
Proofreading dynamics of a processive DNA polymeraseQ37359994
Crystallographic snapshots of a replicative DNA polymerase encountering an abasic siteQ37543875
Fingers-closing and other rapid conformational changes in DNA polymerase I (Klenow fragment) and their role in nucleotide selectivityQ38291078
A single-molecule nanopore device detects DNA polymerase activity with single-nucleotide resolutionQ39923586
Dynamics of nucleotide incorporation: snapshots revealed by 2-aminopurine fluorescence studiesQ41842674
Specific nucleotide binding and rebinding to individual DNA polymerase complexes captured on a nanoporeQ43148060
The bacteriophage phi 29 DNA polymerase, a proofreading enzymeQ43932585
Using 2-aminopurine fluorescence to detect bacteriophage T4 DNA polymerase-DNA complexes that are important for primer extension and proofreading reactions.Q46824092
A conserved 3'----5' exonuclease active site in prokaryotic and eukaryotic DNA polymerasesQ69747222
P4510describes a project that usesImageJQ1659584
P433issue16
P407language of work or nameEnglishQ1860
P921main subjectnanoporeQ580942
P1104number of pages15
P304page(s)13407-13421
P577publication date2012-02-29
P1433published inJournal of Biological ChemistryQ867727
P1476titleDirect observation of translocation in individual DNA polymerase complexes
Direct Observation of Translocation in Individual DNA Polymerase Complexes
P478volume287

Reverse relations

cites work (P2860)
Q50950838Advances in Structural and Single-Molecule Methods for Investigating DNA Lesion Bypass and Repair Polymerases.
Q33767390Coliphage HK022 Nun protein inhibits RNA polymerase translocation
Q37313036Computational simulation strategies for analysis of multisubunit RNA polymerases
Q26740010DNA-Binding Proteins Essential for Protein-Primed Bacteriophage Φ29 DNA Replication
Q42509663Dynamics of the Translocation Step Measured in Individual DNA Polymerase Complexes
Q37622517Dynamics of translocation and substrate binding in individual complexes formed with active site mutants of {phi}29 DNA polymerase
Q42172633Entropic cages for trapping DNA near a nanopore.
Q42546041Kinetic Mechanism of Translocation and dNTP Binding in Individual DNA Polymerase Complexes
Q40350983Kinetic mechanism at the branchpoint between the DNA synthesis and editing pathways in individual DNA polymerase complexes
Q38302451Kinetic mechanisms governing stable ribonucleotide incorporation in individual DNA polymerase complexes
Q39771626Mechano-chemical kinetics of DNA replication: identification of the translocation step of a replicative DNA polymerase
Q36744779Modulation of DNA Polymerase Noncovalent Kinetic Transitions by Divalent Cations
Q27323040Molecular events during translocation and proofreading extracted from 200 static structures of DNA polymerase.
Q36785077RNA polymerase stalls in a post-translocated register and can hyper-translocate
Q34519338Single-Molecule Investigation of Response to Oxidative DNA Damage by a Y-Family DNA Polymerase

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