| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/S0065-3233(04)68001-6 |
| P698 | PubMed publication ID | 15500857 |
| P2093 | author name string | Daniel J Leahy | |
| P2860 | cites work | EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization | Q24296900 |
| Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha | Q24307630 | ||
| Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains | Q24307661 | ||
| Human growth hormone and extracellular domain of its receptor: crystal structure of the complex | Q24308045 | ||
| MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures | Q26778412 | ||
| Structure of the extracellular region of HER3 reveals an interdomain tether | Q27639450 | ||
| Structure of the epidermal growth factor receptor kinase domain alone and in complex with a 4-anilinoquinazoline inhibitor | Q27639528 | ||
| Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab | Q27640593 | ||
| The crystal structure of a truncated ErbB2 ectodomain reveals an active conformation, poised to interact with other ErbB receptors | Q27640631 | ||
| Crystal structure of the first three domains of the type-1 insulin-like growth factor receptor | Q27764901 | ||
| Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. | Q27824766 | ||
| Cell signaling by receptor tyrosine kinases | Q27860474 | ||
| Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene | Q27860693 | ||
| Untangling the ErbB signalling network | Q27860884 | ||
| Deletion-mutant epidermal growth factor receptor in human gliomas: Effect of type II mutation on receptor function | Q28119050 | ||
| Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets | Q28140238 | ||
| The deaf and the dumb: the biology of ErbB-2 and ErbB-3 | Q28185247 | ||
| ErbB-4: mechanism of action and biology | Q28185260 | ||
| Functional analysis of the ligand binding site of EGF-receptor utilizing chimeric chicken/human receptor molecules. | Q40817131 | ||
| Requirement for neuregulin receptor erbB2 in neural and cardiac development | Q41269625 | ||
| The extracellular domain of the epidermal growth factor receptor. Studies on the affinity and stoichiometry of binding, receptor dimerization and a binding-domain mutant | Q41438473 | ||
| Rescue of the cardiac defect in ErbB2 mutant mice reveals essential roles of ErbB2 in peripheral nervous system development | Q41678095 | ||
| Oncogenic activation of the neu-encoded receptor protein by point mutation and deletion | Q42289065 | ||
| Dimerization of the p185neu transmembrane domain is necessary but not sufficient for transformation | Q42803794 | ||
| erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells | Q42807469 | ||
| Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185. | Q42811529 | ||
| The neu oncogene encodes an epidermal growth factor receptor-related protein | Q42812960 | ||
| Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth | Q44120544 | ||
| Signal transduction. Autoinhibition control | Q44429540 | ||
| The erbB gene of avian erythroblastosis virus is a member of the src gene family | Q45797657 | ||
| Transforming capacities of avian erythroblastosis virus mutants deleted in the erbA or erbB oncogenes | Q45798967 | ||
| Thermodynamic analysis of an antibody functional epitope | Q46460317 | ||
| Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor | Q46766121 | ||
| Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor | Q48369441 | ||
| On the tertiary structure of the extracellular domains of the epidermal growth factor and insulin receptors. | Q52464078 | ||
| Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences. | Q53554133 | ||
| Strain-dependent epithelial defects in mice lacking the EGF receptor | Q58326927 | ||
| Epidermal growth factor | Q68951248 | ||
| Insulin and epidermal growth factor receptors contain the cysteine repeat motif found in the tumor necrosis factor receptor | Q71763596 | ||
| Evolutionary analysis of the ErbB receptor and ligand families | Q73819722 | ||
| Oncogenic kinase signalling | Q28189493 | ||
| An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors | Q28207289 | ||
| Severe neuropathies in mice with targeted mutations in the ErbB3 receptor | Q28251972 | ||
| Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype | Q28509173 | ||
| Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor | Q28509287 | ||
| All autophosphorylation sites of epidermal growth factor (EGF) receptor and HER2/neu are located in their carboxyl-terminal tails. Identification of a novel site in EGF receptor | Q28626012 | ||
| Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells | Q29616544 | ||
| The ErbB signaling network: receptor heterodimerization in development and cancer | Q29617919 | ||
| Sequence plasticity in the antigen-binding site of a therapeutic anti-HER2 antibody | Q31106951 | ||
| Anti-synthetic peptide antibody reacting at the fusion junction of deletion-mutant epidermal growth factor receptors in human glioblastoma | Q33610591 | ||
| Increased tyrosine kinase activity associated with the protein encoded by the activated neu oncogene | Q33634411 | ||
| Receptor signaling: when dimerization is not enough | Q33723925 | ||
| Two EGF molecules contribute additively to stabilization of the EGFR dimer | Q33885990 | ||
| Single-molecule imaging of EGFR signalling on the surface of living cells | Q33892648 | ||
| HER2/neu: mechanisms of dimerization/oligomerization | Q34130541 | ||
| Receptors for epidermal growth factor and other polypeptide mitogens | Q34163558 | ||
| Epidermal growth factor induces rapid, reversible aggregation of the purified epidermal growth factor receptor | Q34180911 | ||
| Epidermal Growth Factor | Q34192014 | ||
| Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex | Q34314489 | ||
| Mechanism of action of trastuzumab and scientific update | Q34437163 | ||
| ErbB-targeted therapeutic approaches in human cancer | Q34532249 | ||
| Overview of epidermal growth factor receptor biology and its role as a therapeutic target in human neoplasia | Q34992235 | ||
| Specific radiolabeling of a cell surface receptor for epidermal growth factor | Q35035114 | ||
| The ErbB receptors and their role in cancer progression. | Q35089324 | ||
| Insect cell-expressed p180erbB3 possesses an impaired tyrosine kinase activity | Q35684026 | ||
| The tethered configuration of the EGF receptor extracellular domain exerts only a limited control of receptor function | Q35729931 | ||
| The ErbB-2/HER2 oncoprotein of human carcinomas may function solely as a shared coreceptor for multiple stroma-derived growth factors | Q36334739 | ||
| Oligomerization of epidermal growth factor receptors on A431 cells studied by time-resolved fluorescence imaging microscopy. A stereochemical model for tyrosine kinase receptor activation | Q36535729 | ||
| Anti-sense transforming growth factor alpha oligonucleotides inhibit autocrine stimulated proliferation of a colon carcinoma cell line | Q37374782 | ||
| Interaction between proteins localized in membranes | Q37396417 | ||
| Nobel lecture. Epidermal growth factor | Q39767785 | ||
| Transformation by murine and feline sarcoma viruses specifically blocks binding of epidermal growth factor to cells | Q40035220 | ||
| Local aggregation of hormone–receptor complexes is required for activation by epidermal growth factor | Q40226398 | ||
| Isolation of the human placenta receptor for epidermal growth factor-urogastrone | Q40298265 | ||
| Dimerization of cell surface receptors in signal transduction | Q40579106 | ||
| Epidermal growth factor stimulates phosphorylation in membrane preparations in vitro | Q40693948 | ||
| Direct visualization of the binding and internalization of a ferritin conjugate of epidermal growth factor in human carcinoma cells A-431 | Q40718358 | ||
| Identification of the EGF receptor on 3T3 cells by surface-specific iodination and gel electrophoresis | Q40720756 | ||
| Activation of preformed EGF receptor dimers by ligand-induced rotation of the transmembrane domain | Q40782870 | ||
| Identification of a determinant of epidermal growth factor receptor ligand-binding specificity using a truncated, high-affinity form of the ectodomain. | Q40790583 | ||
| P304 | page(s) | 1-27 | |
| P577 | publication date | 2004-01-01 | |
| P1433 | published in | Advances in Protein Chemistry | Q15756442 |
| P1476 | title | Structure and function of the epidermal growth factor (EGF/ErbB) family of receptors | |
| P478 | volume | 68 |
| Q35674768 | A structural perspective on the regulation of the epidermal growth factor receptor |
| Q34554113 | Activation of stem cells in hepatic diseases. |
| Q35917462 | Analysis of the Role of the C-Terminal Tail in the Regulation of the Epidermal Growth Factor Receptor |
| Q40416072 | Differentiation of a mouse submandibular gland-derived cell line (SCA) grown on matrigel |
| Q37520544 | Dual inhibition of ErbB1 and ErbB2 in cancer by recombinant human prolidase mutant hPEPD-G278D. |
| Q28066531 | EGF receptor ligands: recent advances |
| Q39626743 | Epidermal growth factor receptor transactivation is implicated in IL-6-induced proliferation and ERK1/2 activation in non-transformed prostate epithelial cells |
| Q52652923 | Exploring the dynamics and interaction of a full ErbB2 receptor and Trastuzumab-Fab antibody in a lipid bilayer model using Martini coarse-grained force field. |
| Q37210747 | Filamin A modulates kinase activation and intracellular trafficking of epidermal growth factor receptors in human melanoma cells |
| Q36701254 | GLI pathogenesis-related 1 functions as a tumor-suppressor in lung cancer |
| Q35749374 | HER2 therapy. HER2 (ERBB2): functional diversity from structurally conserved building blocks |
| Q36958226 | Human epidermal growth factor receptor 2-positive breast cancer: which cytotoxic agent best complements trastuzumab's efficacy in vitro? |
| Q35733827 | Inhibition of ERBB2-overexpressing Tumors by Recombinant Human Prolidase and Its Enzymatically Inactive Mutant |
| Q36625236 | Inhibitors of signal transduction protein kinases as targets for cancer therapy |
| Q37320814 | Interaction of antibodies with ErbB receptor extracellular regions |
| Q35121287 | Kinase activator-receiver preference in ErbB heterodimers is determined by intracellular regions and is not coupled to extracellular asymmetry |
| Q39242623 | Ligand binding induces a conformational change in epidermal growth factor receptor dimers. |
| Q35641650 | Loss of Hsp90 association up-regulates Src-dependent ErbB2 activity |
| Q36993693 | Molecular basis for multimerization in the activation of the epidermal growth factor receptor |
| Q57061981 | Natural molecules induce and synergize to boost expression of the human antimicrobial peptide β-defensin-3 |
| Q34674982 | Proinflammatory and profibrotic mediators: principal effectors of leiomyoma development as a fibrotic disorder |
| Q36561975 | Prolidase directly binds and activates epidermal growth factor receptor and stimulates downstream signaling |
| Q37145814 | Protein arginine methyltransferase 5 regulates multiple signaling pathways to promote lung cancer cell proliferation |
| Q28083779 | Receptor tyrosine kinase signaling: regulating neural crest development one phosphate at a time |
| Q42830070 | Role of epidermal growth factor and ErbB2 receptors in 3T3-L1 adipogenesis |
| Q39123535 | Single molecular dissection of the ligand binding property of epidermal growth factor receptor |
| Q42066556 | Stretch-induced mitogen-activated protein kinase activation in lung fibroblasts is independent of receptor tyrosine kinases |
| Q90179057 | Structural characterization of EGFR exon 19 deletion mutation using molecular dynamics simulation |
| Q37197992 | Structure-based view of epidermal growth factor receptor regulation |
| Q53145380 | Study of proliferative processes and nuclear estradiol and progesterone receptors in myocytes in pregnant and postpartum mouse uterus. |
| Q34272044 | Targeting HER2 in breast cancer: overview of long-term experience |
| Q37135372 | The ERBB3 receptor in cancer and cancer gene therapy |
| Q39109678 | The diversity and plasticity of adult hepatic progenitor cells and their niche |
| Q37602303 | The epidermal growth factor system of ligands and receptors in cancer |
| Q41972324 | The in vitro influences of epidermal growth factor and heregulin-β1 on the efficacy of trastuzumab used in Her-2 positive breast adenocarcinoma |
| Q38034347 | The promise of anti-ErbB3 monoclonals as new cancer therapeutics |
| Q42157094 | Transforming growth factor alpha attenuates the functional expression of AMPA receptors in cortical GABAergic neurons |
Search more.