ETV6-RUNX1-positive childhood acute lymphoblastic leukemia: improved outcome with contemporary therapy.

scientific article

ETV6-RUNX1-positive childhood acute lymphoblastic leukemia: improved outcome with contemporary therapy. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/LEU.2011.227
P932PMC publication ID3345278
P698PubMed publication ID21869842
P5875ResearchGate publication ID51598010

P50authorJeffrey RubnitzQ57306302
Monika L MetzgerQ91391717
Deepa BhojwaniQ42324985
P2093author name stringD Pei
S C Raimondi
M V Relling
W E Evans
H Inaba
D Campana
E Coustan-Smith
W Leung
C Cheng
C-H Pui
J T Sandlund
R C Ribeiro
S Jeha
W P Bowman
S C Howard
M Onciu
S Shurtleff
P2860cites workIncidence and clinical relevance of TEL/AML1 fusion genes in children with acute lymphoblastic leukemia enrolled in the German and Italian multicenter therapy trials. Associazione Italiana Ematologia Oncologia Pediatrica and the Berlin-Frankfurt-MünQ52999147
Prognostic effect of chromosomal abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: results from the UK Medical Research Council ALL97/99 randomised trialQ58481820
Outcome of ETV6/RUNX1-positive childhood acute lymphoblastic leukaemia in the NOPHO-ALL-1992 protocol: frequent late relapses but good overall survivalQ61643142
L-asparaginase may potentiate the leukemogenic effect of the epipodophyllotoxinsQ71755657
TEL gene rearrangement in acute lymphoblastic leukemia: a new genetic marker with prognostic significanceQ73132199
Prenatal origin of acute lymphoblastic leukaemia in childrenQ73156477
Prognostic importance of measuring early clearance of leukemic cells by flow cytometry in childhood acute lymphoblastic leukemiaQ74314236
Novel cryptic, complex rearrangements involving ETV6-CBFA2 (TEL-AML1) genes identified by fluorescence in situ hybridization in pediatric patients with acute lymphoblastic leukemiaQ74495609
Early intensification of intrathecal chemotherapy virtually eliminates central nervous system relapse in children with acute lymphoblastic leukemiaQ74765433
TEL-AML1 promotes development of specific hematopoietic lineages consistent with preleukemic activityQ75272861
Acute lymphoblastic leukemiaQ79891876
Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemiaQ24319864
Treating childhood acute lymphoblastic leukemia without cranial irradiationQ24644599
Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemiaQ29614324
Chemosensitivity of TEL-AML1 fusion transcript positive acute lymphoblastic leukemia cellsQ30671189
Evaluation of survival data and two new rank order statistics arising in its considerationQ34054360
Escalating intravenous methotrexate improves event-free survival in children with standard-risk acute lymphoblastic leukemia: a report from the Children's Oncology GroupQ35112206
Mesenchymal cells regulate the response of acute lymphoblastic leukemia cells to asparaginaseQ35677647
Prospective analysis of TEL gene rearrangements in childhood acute lymphoblastic leukemia: a Children's Oncology Group studyQ35797316
Prospective analysis of TEL/AML1-positive patients treated on Dana-Farber Cancer Institute Consortium Protocol 95-01.Q35849716
The TEL-AML1 leukemia fusion gene dysregulates the TGF-beta pathway in early B lineage progenitor cellsQ37143354
Translocation t(12;21) is related to in vitro cellular drug sensitivity to doxorubicin and etoposide in childhood acute lymphoblastic leukemiaQ40541692
Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 studyQ43162649
Vincristine but not imatinib could suppress mesenchymal niche's support to lymphoid leukemic cells.Q43238735
TEL/AML1 gene fusion is related to in vitro drug sensitivity for L-asparaginase in childhood acute lymphoblastic leukemia.Q43505473
Dexamethasone versus prednisone and daily oral versus weekly intravenous mercaptopurine for patients with standard-risk acute lymphoblastic leukemia: a report from the Children's Cancer GroupQ44280928
Improved outcome for children with acute lymphoblastic leukemia: results of Total Therapy Study XIIIB at St Jude Children's Research HospitalQ44976795
Asparaginase may influence dexamethasone pharmacokinetics in acute lymphoblastic leukemiaQ46638043
The 12;21 translocation involving TEL and deletion of the other TEL allele: two frequently associated alterations found in childhood acute lymphoblastic leukemiaQ47335313
The association of the TEL-AML1 chromosomal translocation with the accumulation of methotrexate polyglutamates in lymphoblasts and with ploidy in childhood B-progenitor cell acute lymphoblastic leukemia: a Pediatric Oncology Group studyQ49279595
P433issue2
P921main subjectleukemiaQ29496
lymphoblastic leukemiaQ18553852
P304page(s)265-270
P577publication date2011-08-26
P1433published inLeukemiaQ6534498
P1476titleETV6-RUNX1-positive childhood acute lymphoblastic leukemia: improved outcome with contemporary therapy
P478volume26

Reverse relations

cites work (P2860)
Q37166753A 50-year journey to cure childhood acute lymphoblastic leukemia
Q58481753Acute lymphoblastic leukaemia
Q58481759Acute lymphoblastic leukemia
Q45071531An investigation of toxicities and survival in Hispanic children and adolescents with ALL: Results from the Dana-Farber Cancer Institute ALL Consortium protocol 05-001.
Q52877394Childhood acute lymphoblastic leukemia: 12 years of experience, using a Berlin-Frankfurt-Münster approach, in a Greek center.
Q38194444Chromatin modifiers and the promise of epigenetic therapy in acute leukemia
Q38904250Clinical Relevance of RUNX1 and CBFB Alterations in Acute Myeloid Leukemia and Other Hematological Disorders
Q54295812Clinical features, early treatment responses, and outcomes of pediatric acute lymphoblastic leukemia in China with or without specific fusion transcripts: a single institutional study of 1,004 patients.
Q49716164Clinical significance of monitoring ETV6-RUNX1 fusion gene expression in children with acute lymphoblastic leukemia after allogeneic hematopoietic stem cell transplantation
Q46279150Copy number alterations determined by single nucleotide polymorphism array testing in the clinical laboratory are indicative of gene fusions in pediatric cancer patients
Q36528412Determination of ETV6-RUNX1 genomic breakpoint by next-generation sequencing
Q47175107Differential impact of drugs on the outcome of ETV6-RUNX1 positive childhood B-cell precursor acute lymphoblastic leukaemia: results of the EORTC CLG 58881 and 58951 trials
Q58774001ETV6/RUNX1-positive childhood acute lymphoblastic leukemia in China: excellent prognosis with improved BFM protocol
Q36366644Excellent prognosis of late relapses of ETV6/RUNX1-positive childhood acute lymphoblastic leukemia: lessons from the FRALLE 93 protocol
Q37359118Genomic characterization of childhood acute lymphoblastic leukemia
Q34500075Germline genetic variation in ETV6 and risk of childhood acute lymphoblastic leukaemia: a systematic genetic study
Q34598903Impact of tyrosine kinase inhibitors on minimal residual disease and outcome in childhood Philadelphia chromosome-positive acute lymphoblastic leukemia
Q38748648Leukaemia 'firsts' in cancer research and treatment
Q51026411Long-term follow-up of ETV6-RUNX1 ALL reveals that NCI risk, rather than secondary genetic abnormalities, is the key risk factor.
Q48125822Minimal residual disease monitoring in childhood B lymphoblastic leukemia with t(12;21)(p13;q22); ETV6-RUNX1: concordant results using quantitation of fusion transcript and flow cytometry
Q48218289Molecular processes involved in B cell acute lymphoblastic leukaemia.
Q26749177New and emerging prognostic and predictive genetic biomarkers in B-cell precursor acute lymphoblastic leukemia
Q33584136Outcome and Prognostic Factors for ETV6/RUNX1 Positive Pediatric Acute Lymphoblastic Leukemia Treated at a Single Institution in Korea
Q36163029Pediatric acute lymphoblastic leukemia: where are we going and how do we get there?
Q35074246Pediatric donor cell leukemia after allogeneic hematopoietic stem cell transplantation in AML patient from related donor
Q39425967Pediatric haematopoiesis and related malignancies
Q55486808Phase II/III study in children and adolescents with newly diagnosed B-cell precursor acute lymphoblastic leukemia: protocol for a nationwide multicenter trial in Japan.
Q33770150Prognostic factors and treatment of pediatric acute lymphoblastic leukemia
Q28087446Prognostification of ALL by Cytogenetics
Q98772371Quantitative monitoring of minimal residual disease in childhood acute lymphoblastic leukemia using TEL-AML1 fusion transcript as a marker
Q38367298RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia
Q28597831RUNX1 truncation resulting from a cryptic and novel t(6;21)(q25;q22) chromosome translocation in acute myeloid leukemia: A case report
Q33566597Runx1 stabilizes the mammary epithelial cell phenotype and prevents epithelial to mesenchymal transition
Q37292721Targeted Theranostic Approach for Glioma Using Dendrimer-Based Curcumin Nanoparticle
Q38017727Targeting the liver kinase B1/AMP-activated protein kinase pathway as a therapeutic strategy for hematological malignancies

Search more.