Naturally occurring eccentric cleavage products of provitamin A β-carotene function as antagonists of retinoic acid receptors

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Naturally occurring eccentric cleavage products of provitamin A β-carotene function as antagonists of retinoic acid receptors is …
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scholarly articleQ13442814

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P356DOI10.1074/JBC.M111.325142
P932PMC publication ID3346154
P698PubMed publication ID22418437
P5875ResearchGate publication ID221896111

P2093author name stringDamian P Hruszkewycz
Earl H Harrison
Ken M Riedl
Rachel E Kopec
Robert W Curley
Steven J Schwartz
Sureshbabu Narayanasamy
Abdulkerim Eroglu
Carlo dela Sena
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All-trans-retinol is a ligand for the retinoic acid receptorsQ36460690
Carotene and novel apocarotenoid concentrations in orange-fleshed Cucumis melo melons: determinations of β-carotene bioaccessibility and bioavailabilityQ36530838
Hepatic stellate cells are an important cellular site for β-carotene conversion to retinoidQ36954390
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{beta}-Apocarotenoids do not significantly activate retinoic acid receptors {alpha} or {beta}.Q41865331
The eccentric cleavage product of β-carotene, β-apo-13-carotenone, functions as an antagonist of RXRα.Q41941029
Vitamin A and carotene: The absence of the liver oil vitamin A from carotene. VI. The conversion of carotene to vitamin A in vivoQ42572892
Asymmetric cleavage of beta-carotene yields a transcriptional repressor of retinoid X receptor and peroxisome proliferator-activated receptor responsesQ42835054
Characterization of beta-apo-13-carotenone and beta-apo-14'-carotenal as enzymatic products of the excentric cleavage of beta-caroteneQ45278174
Excentral cleavage of beta-carotene in vivo in a healthy man.Q46535023
Beta-carotene and beta-apo-14'-carotenoic acid prevent the reduction of retinoic acid receptor beta in benzo[a]pyrene-treated normal human bronchial epithelial cellsQ48013953
Docking of hydrophobic ligands with interaction-based matching algorithms.Q51646570
Effects of physiological versus pharmacological beta-carotene supplementation on cell proliferation and histopathological changes in the lungs of cigarette smoke-exposed ferrets.Q53402952
Retinoid signaling and activator protein-1 expression in ferrets given beta-carotene supplements and exposed to tobacco smoke.Q53427307
Enzymatic conversion of beta-carotene into beta-apo-carotenals and retinoids by human, monkey, ferret, and rat tissuesQ67983042
P433issue19
P407language of work or nameEnglishQ1860
P921main subjecttretinoinQ29417
P304page(s)15886-15895
P577publication date2012-03-14
P1433published inJournal of Biological ChemistryQ867727
P1476titleNaturally occurring eccentric cleavage products of provitamin A β-carotene function as antagonists of retinoic acid receptors
P478volume287

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