In vitro evolution of a highly replicating, doxycycline-dependent HIV for applications in vaccine studies

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In vitro evolution of a highly replicating, doxycycline-dependent HIV for applications in vaccine studies is …
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scholarly articleQ13442814

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P819ADS bibcode2001PNAS...98.6342M
P356DOI10.1073/PNAS.111031498
P932PMC publication ID33470
P698PubMed publication ID11353837
P5875ResearchGate publication ID11983755

P2093author name stringBerkhout B
Verhoef K
Marzio G
Vink M
P2860cites workHuman neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infectionQ45744790
Live attenuated, multiply deleted simian immunodeficiency virus causes AIDS in infant and adult macaquesQ45751494
Resistance of neonatal monkeys to live attenuated vaccine strains of simian immunodeficiency virusQ45765427
Protection by attenuated simian immunodeficiency virus in macaques against challenge with virus-infected cells.Q45785662
Switching transgene expression in the brain using an adenoviral tetracycline-regulatable systemQ45887839
A role for carbohydrates in immune evasion in AIDSQ47982875
Viral Dynamics in HIV-1 InfectionQ52038970
Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemiaQ57075698
Dox-dependent SIVmac with tetracycline-inducible promoter in the U3 promoter regionQ73642650
Is an HIV vaccine possible?Q77890089
Declining CD4 T-cell counts in a person infected with nef-deleted HIV-1Q77901004
HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoterQ22007982
Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodiesQ29614531
Importance of the nef gene for maintenance of high virus loads and for development of AIDSQ29618369
Protective effects of a live attenuated SIV vaccine with a deletion in the nef geneQ33196552
Immunologic and virologic status after 14 to 18 years of infection with an attenuated strain of HIV-1. A report from the Sydney Blood Bank CohortQ33443744
Pathogenicity of live, attenuated SIV after mucosal infection of neonatal macaquesQ33490720
Strategies used by human immunodeficiency virus that allow persistent viral replicationQ33680601
Evidence for recombination of live, attenuated immunodeficiency virus vaccine with challenge virus to a more virulent strain.Q33802066
Highly attenuated vaccine strains of simian immunodeficiency virus protect against vaginal challenge: inverse relationship of degree of protection with level of attenuationQ33814150
Protection by live, attenuated simian immunodeficiency virus against heterologous challenge.Q33820014
Strict control of human immunodeficiency virus type 1 replication by a genetic switch: Tet for Tat.Q33835795
Biological considerations in the development of a human immunodeficiency virus vaccineQ33983937
Multiple biological roles associated with the repeat (R) region of the HIV-1 RNA genomeQ34033118
Live attenuated HIV vaccines: a proposal for further research and development.Q34071750
A conserved hairpin motif in the R-U5 region of the human immunodeficiency virus type 1 RNA genome is essential for replicationQ35879394
Development of AIDS in a chimpanzee infected with human immunodeficiency virus type 1Q35884252
Live, attenuated simian immunodeficiency virus vaccines elicit potent resistance against a challenge with a human immunodeficiency virus type 1 chimeric virusQ35897786
Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme.Q35905947
A partially attenuated simian immunodeficiency virus induces host immunity that correlates with resistance to pathogenic virus challenge.Q36636854
A hairpin structure in the R region of the human immunodeficiency virus type 1 RNA genome is instrumental in polyadenylation site selectionQ39548579
Genetic instability of live, attenuated human immunodeficiency virus type 1 vaccine strainsQ39549272
A pathogenic threshold of virus load defined in simian immunodeficiency virus- or simian-human immunodeficiency virus-infected macaquesQ39583691
Functional differences between the long terminal repeat transcriptional promoters of human immunodeficiency virus type 1 subtypes A through G.Q39590547
Repair and evolution of nef in vivo modulates simian immunodeficiency virus virulenceQ39871310
Vaccine protection by a triple deletion mutant of simian immunodeficiency virus.Q39874667
Can the immune response control HIV infection?Q40456329
Mechanisms underlying expression of Tn10 encoded tetracycline resistanceQ40572946
Tet repressor-based system for regulated gene expression in eukaryotic cells: principles and advancesQ40846822
HIV-1 evolves into a nonsyncytium-inducing virus upon prolonged culture in vitro.Q40920580
Quantitative dynamics of HIV type 1 expressionQ41237667
Doxycycline RevisitedQ41532100
Progress in the Development of an HIV-1 VaccineQ45147943
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectvaccineQ134808
doxycyclineQ422442
P304page(s)6342-6347
P577publication date2001-05-15
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleIn vitro evolution of a highly replicating, doxycycline-dependent HIV for applications in vaccine studies
P478volume98

Reverse relations

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