Glucocorticoids: protectors of the brain during innate immune responses

scientific article

Glucocorticoids: protectors of the brain during innate immune responses is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1177/1073858404263494
P698PubMed publication ID15534039
P5875ResearchGate publication ID8186955

P2093author name stringSerge Rivest
Isaias Glezer
P2860cites workTollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptorQ22254266
Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 GeneQ22299417
SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signalingQ24316441
Recognition of pneumococcal peptidoglycan: an expanded, pivotal role for LPS binding proteinQ24317469
Cytokines and acute neurodegenerationQ28190084
Negative regulation of toll-like receptor-mediated signaling by TollipQ28212686
TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathwayQ28505835
Endotoxemia prevents the cerebral inflammatory wave induced by intraparenchymal lipopolysaccharide injection: role of glucocorticoids and CD14Q28579939
Identification of Lps2 as a key transducer of MyD88-independent TIR signallingQ28587545
Missing pieces in the NF-kappaB puzzleQ29547864
Toll-like receptors: critical proteins linking innate and acquired immunityQ29615190
Social stress exacerbates focal cerebral ischemia in miceQ32127267
The Toll-receptor family and control of innate immunityQ33536547
Microglia as mediators of inflammatory and degenerative diseasesQ33593415
Glucocorticoids in central nervous system bacterial infectionQ33686644
Tlr4: central component of the sole mammalian LPS sensorQ33840545
Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shockQ34145159
Glucocorticoid resistance and the immune function in the immunodeficiency syndromeQ47966350
Cooperation between toll-like receptor 2 and 4 in the brain of mice challenged with cell wall components derived from gram-negative and gram-positive bacteriaQ47997759
Effects of systemic immunogenic insults and circulating proinflammatory cytokines on the transcription of the inhibitory factor kappaB alpha within specific cellular populations of the rat brainQ48175000
The acute inflammatory response to lipopolysaccharide in CNS parenchyma differs from that in other body tissuesQ48563726
Circulating cell wall components derived from gram-negative, not gram-positive, bacteria cause a profound induction of the gene-encoding Toll-like receptor 2 in the CNS.Q48716364
Spatiotemporal induction patterns of cytokine and related immune signal molecule mRNAs in response to intrastriatal injection of lipopolysaccharide.Q51973832
Induction of proinflammatory molecules in mice with amyotrophic lateral sclerosis: no requirement for proapoptotic interleukin-1beta in neurodegeneration.Q52544555
Inverse association of anti-inflammatory treatments and Alzheimer's disease: initial results of a co-twin control study.Q52884779
A randomized controlled trial of prednisone in Alzheimer's disease. Alzheimer's Disease Cooperative Study.Q53233235
Decreased peripheral glucocorticoid sensitivity in Alzheimer's disease.Q53317469
Gene profiling reveals unknown enhancing and suppressive actions of glucocorticoids on immune cellsQ56933005
LIF receptor signaling limits immune-mediated demyelination by enhancing oligodendrocyte survivalQ58425803
???Q24291418
"Eat me" and "don't eat me" signals govern the innate immune response and tissue repair in the CNS: emphasis on the critical role of the complement systemQ34221774
How the immune system works to protect the host from infection: a personal viewQ34272671
Sepsis and evolution of the innate immune responseQ34303773
Action of glucocorticoids on survival of nerve cells: promoting neurodegeneration or neuroprotection?Q34385964
Toll-like receptors: how they work and what they do.Q34468201
Toll-like receptors: key mediators of microbe detection.Q34493051
Neuronal injury in bacterial meningitis: mechanisms and implications for therapyQ34500860
Innate immunity: the missing link in neuroprotection and neurodegeneration?Q34627260
The bacterial endotoxin lipopolysaccharide has the ability to target the brain in upregulating its membrane CD14 receptor within specific cellular populationsQ34663653
Coregulator proteins and corticosteroid action in the brain.Q34669513
Regulation of leukocyte-endothelial interactions by glucocorticoids.Q34735549
Inflammation in neurodegenerative disease--a double-edged swordQ34775762
Rapid nontranscriptional activation of endothelial nitric oxide synthase mediates increased cerebral blood flow and stroke protection by corticosteroids.Q34816365
Glucocorticoids and central nervous system inflammationQ35022584
Molecular mechanisms of glucocorticoid action and resistanceQ35089953
Actions of glucocorticoids and related molecules after traumatic brain injuryQ35092386
Novel strategies for the treatment of sepsisQ35118750
Pathogenesis of bacterial meningitis: from bacteraemia to neuronal injuryQ35120141
Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathwayQ35168537
Recognition of microbial infection by Toll-like receptorsQ35192575
How we detect microbes and respond to them: the Toll-like receptors and their transducersQ35213803
Lack of tissue glucocorticoid reactivation in 11beta -hydroxysteroid dehydrogenase type 1 knockout mice ameliorates age-related learning impairmentsQ35300139
Polyamines play a critical role in the control of the innate immune response in the mouse central nervous system.Q36323217
Distinct mutations in IRAK-4 confer hyporesponsiveness to lipopolysaccharide and interleukin-1 in a patient with recurrent bacterial infectionsQ36371624
Why stress is bad for your brainQ36807143
Effects of chronic intrahippocampal infusion of lipopolysaccharide in the rat.Q36824551
Glucocorticoids and immune function: physiological relevance and pathogenic potential of hormonal dysfunctionQ40469890
Early environmental regulation of forebrain glucocorticoid receptor gene expression: implications for adrenocortical responses to stressQ41138577
Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesisQ41283113
Heterodimerization between mineralocorticoid and glucocorticoid receptors increases the functional diversity of corticosteroid actionQ41293660
Cytokines which signal through the LIF receptor and their actions in the nervous systemQ41597814
Novel glucocorticoid effects on acute inflammation in the CNS.Q42436545
Toll-like receptor 4: the missing link of the cerebral innate immune response triggered by circulating gram-negative bacterial cell wall componentsQ42498224
Metyrapone, an inhibitor of glucocorticoid production, reduces brain injury induced by focal and global ischemia and seizuresQ42528099
The hypothalamic-pituitary-adrenal axis of patients with severe sepsis: altered response to corticotropin-releasing hormoneQ43541017
Effect of corticosteroids on nuclear factor-kappaB activation and hemodynamics in late septic shockQ43621728
The degenerative effect of a single intranigral injection of LPS on the dopaminergic system is prevented by dexamethasone, and not mimicked by rh-TNF-alpha, IL-1beta and IFN-gammaQ44029772
Slowing the progression of cognitive decline in Alzheimer's disease using mifepristoneQ44125962
In altering the release of glucocorticoids, ketorolac exacerbates the effects of systemic immune stimuli on expression of proinflammatory genes in the brainQ44226034
MK-801 and 7-Ni attenuate the activation of brain NF-kappa B induced by LPS.Q44654041
P433issue6
P304page(s)538-552
P577publication date2004-12-01
P1433published inThe NeuroscientistQ7753449
P1476titleGlucocorticoids: protectors of the brain during innate immune responses
P478volume10

Reverse relations

cites work (P2860)
Q36019327An inflammatory review of glucocorticoid actions in the CNS.
Q36119940Cell type-specific expression and function of toll-like receptors 2 and 4 in human placenta: implications in fetal infection
Q35590867Chronic stress exacerbates tau pathology, neurodegeneration, and cognitive performance through a corticotropin-releasing factor receptor-dependent mechanism in a transgenic mouse model of tauopathy
Q37935622Cognitive and behavioral consequences of impaired immunoregulation in aging
Q37232659Differential effects of homotypic vs. heterotypic chronic stress regimens on microglial activation in the prefrontal cortex.
Q36944833Disifin (sodium tosylchloramide) and Toll-like receptors (TLRs): evolving importance in health and diseases
Q36273698Do pathogen exposure and innate immunity cause brain diseases?
Q37812669Dysregulated neuronal-microglial cross-talk during aging, stress and inflammation
Q38586635Early adversity, neural development, and inflammation
Q36146959Emerging biological roles for erythropoietin in the nervous system
Q24645038Expression and distribution of Toll-like receptors 11-13 in the brain during murine neurocysticercosis
Q35606759Expression and distribution of Toll-like receptors in the brain during murine neurocysticercosis
Q35070648General anesthetics inhibit LPS-induced IL-1β expression in glial cells
Q33279528Genes involved in the balance between neuronal survival and death during inflammation
Q91970958Glucocorticoid Resistance: Is It a Requisite for Increased Cytokine Production in Depression? A Systematic Review and Meta-Analysis
Q42673840Glucocorticoid receptor dimerization is required for proper recovery of LPS-induced inflammation, sickness behavior and metabolism in mice
Q27024383Glucocorticoid regulation of inflammation and its functional correlates: from HPA axis to glucocorticoid receptor dysfunction
Q48278301Hemodynamic steroid responsiveness is predictive of neurological outcome after traumatic brain injury.
Q37489879Identifying the cellular targets of drug action in the central nervous system following corticosteroid therapy
Q38120744Innate immunity and neuroinflammation
Q38859380Integrating neuroimmune systems in the neurobiology of depression.
Q45036156Lipoic acid and bone marrow derived cells therapy induce angiogenesis and cell proliferation after focal brain injury.
Q36857314MCP-1-deficient mice show reduced neuroinflammatory responses and increased peripheral inflammatory responses to peripheral endotoxin insult
Q29547835Microglia-mediated neurotoxicity: uncovering the molecular mechanisms
Q36739426Molecular and cellular immune mediators of neuroprotection
Q80849152Neuroprotective effects of resident microglia following acute brain injury
Q36402221Neuroprotective properties of the innate immune system and bone marrow stem cells in Alzheimer's disease
Q34110468Polymorphisms in the 3'-untranslated region of human and monkey dopamine transporter genes affect reporter gene expression
Q37336959Psychoneuroimmune implications of type 2 diabetes: redux
Q37492253Regulation of innate immune responses in the brain
Q48554200Study of differentiated human umbilical cord-derived mesenchymal stem cells transplantation on rat model of advanced parkinsonism
Q34170824The PPAR-gamma agonist, darglitazone, restores acute inflammatory responses to cerebral hypoxia-ischemia in the diabetic ob/ob mouse
Q40063227The cellular and genomic response of an immortalized microglia cell line (BV2) to concentrated ambient particulate matter
Q38020956The neuroendocrine control of the innate immune system in health and brain diseases
Q57090611Toll-Like Receptor Signaling Is Critical for Wallerian Degeneration and Functional Recovery after Peripheral Nerve Injury
Q34717894Toll-like receptor-mediated responses by placental Hofbauer cells (HBCs): a potential pro-inflammatory role for fetal M2 macrophages
Q36127395Traumatic brain injury in young rats leads to progressive behavioral deficits coincident with altered tissue properties in adulthood

Search more.