Molecular and functional analysis of the dictyostelium centrosome

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Molecular and functional analysis of the dictyostelium centrosome is …
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review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S0074-7696(04)41003-1
P698PubMed publication ID15548420

P2093author name stringIrene Schulz
Ralph Gräf
Christine Daunderer
P2860cites workNIMA-related kinase 2 (Nek2), a cell-cycle-regulated protein kinase localized to centrosomes, is complexed to protein phosphatase 1Q22254443
A role for the lissencephaly gene LIS1 in mitosis and cytoplasmic dynein functionQ24290458
The centrosomal protein C-Nap1 is required for cell cycle-regulated centrosome cohesionQ24290514
The Golgi-associated hook3 protein is a member of a novel family of microtubule-binding proteinsQ24290898
Centrosome protein centrin 2/caltractin 1 is part of the xeroderma pigmentosum group C complex that initiates global genome nucleotide excision repairQ24291057
Clasps are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblastsQ24291093
GCP5 and GCP6: two new members of the human gamma-tubulin complexQ24291862
Proteomic characterization of the human centrosome by protein correlation profilingQ24301045
Centrin-2 is required for centriole duplication in mammalian cellsQ24304368
TOGp, the human homolog of XMAP215/Dis1, is required for centrosome integrity, spindle pole organization, and bipolar spindle assemblyQ24304453
C-Nap1, a novel centrosomal coiled-coil protein and candidate substrate of the cell cycle-regulated protein kinase Nek2Q24310473
A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators.Q24320294
Centrosome amplification drives chromosomal instability in breast tumor developmentQ24534950
Evidence that an interaction between EB1 and p150(Glued) is required for the formation and maintenance of a radial microtubule array anchored at the centrosomeQ24537259
Analysis of mitotic microtubule-associated proteins using mass spectrometry identifies astrin, a spindle-associated proteinQ24555066
Isolation of centrosomes from DictyosteliumQ74496142
Molecular components of the centrosomeQ75293454
Dictyostelium centrin-related protein (DdCrp), the most divergent member of the centrin family, possesses only two EF hands and dissociates from the centrosome during mitosisQ77194597
Supernumerary centrosomes and cancer: Boveri's hypothesis resurrectedQ77701101
Self-organization of microtubule asters induced in Xenopus egg extracts by GTP-bound RanQ77767628
Stimulation of microtubule aster formation and spindle assembly by the small GTPase RanQ77767632
Searching for the role of protein phosphatases in eukaryotic microorganismsQ78150061
Stu2p and XMAP215: turncoat microtubule-associated proteins?Q79196593
Actin-binding proteins required for reliable chromosome segregation in mitosisQ79334792
Origin and evolution of the slime molds (Mycetozoa)Q24646167
Sfi1p has conserved centrin-binding sites and an essential function in budding yeast spindle pole body duplicationQ24671520
The ch-TOG/XMAP215 protein is essential for spindle pole organization in human somatic cellsQ24672810
A novel human protein of the maternal centriole is required for the final stages of cytokinesis and entry into S phaseQ24675061
Crawling into a new era-the Dictyostelium genome projectQ24675852
Centrin4p, a novel mammalian centrin specifically expressed in ciliated cellsQ24682793
The microtubule plus-end proteins EB1 and dynactin have differential effects on microtubule polymerizationQ24683085
The XMAP215-family protein DdCP224 is required for cortical interactions of microtubulesQ24795534
Localization of core spindle pole body (SPB) components during SPB duplication in Saccharomyces cerevisiae.Q27931643
Molecular analysis of kinetochore-microtubule attachment in budding yeast.Q27931971
Control of microtubule dynamics by Stu2p is essential for spindle orientation and metaphase chromosome alignment in yeastQ27932077
Yeast Bim1p promotes the G1-specific dynamics of microtubules.Q27932240
Yeast Cdk1 translocates to the plus end of cytoplasmic microtubules to regulate bud cortex interactionsQ27932858
Spc98p and Spc97p of the yeast gamma-tubulin complex mediate binding to the spindle pole body via their interaction with Spc110pQ27935960
Analysis of the Saccharomyces spindle pole by matrix-assisted laser desorption/ionization (MALDI) mass spectrometryQ27936980
The yeast spindle pole body component Spc72p interacts with Stu2p and is required for proper microtubule assemblyQ27937620
The calcium-binding protein cell division cycle 31 of Saccharomyces cerevisiae is a component of the half bridge of the spindle pole bodyQ27938729
CLIP-170 highlights growing microtubule ends in vivoQ28117925
Interaction of the p62 subunit of dynactin with Arp1 and the cortical actin cytoskeletonQ28140958
The dynamic behavior of the APC-binding protein EB1 on the distal ends of microtubulesQ28140999
Activity of the human centrosomal kinase, Nek2, depends on an unusual leucine zipper dimerization motifQ28144796
Xeroderma pigmentosum group C protein possesses a high affinity binding site to human centrin 2 and calmodulinQ28190893
Characterization of Functional Domains of Human EB1 Family ProteinsQ28205321
The C. elegans hook protein, ZYG-12, mediates the essential attachment between the centrosome and nucleusQ28236367
NIP1/XB51/NECAB3 is a potential substrate of Nek2, suggesting specific roles of Nek2 in GolgiQ28236436
Microtubule polymerization dynamicsQ28259930
Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCzetaQ28583531
A role for cytoplasmic dynein and LIS1 in directed cell movementQ28591271
Pericentrin, a highly conserved centrosome protein involved in microtubule organizationQ28593709
Nucleation of microtubule assembly by a gamma-tubulin-containing ring complexQ29615059
Conserved microtubule-actin interactions in cell movement and morphogenesisQ29615212
Behavior of spindles and spindle plaques in the cell cycle and conjugation of Saccharomyces cerevisiaeQ29618381
Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeletonQ29620156
Components of the yeast spindle and spindle pole bodyQ29620925
Dictyostelium EB1 is a genuine centrosomal component required for proper spindle formationQ30476010
The actin-bundling protein cortexillin is the downstream target of a Rac1-signaling pathway required for cytokinesisQ35210333
The good, the bad and the ugly: the practical consequences of centrosome amplificationQ35705371
Variations on a theme: the many modes of cytokinesis.Q35705375
Adenomatous polyposis coli and EB1 localize in close proximity of the mother centriole and EB1 is a functional component of centrosomes.Q36012450
Spindle and kinetochore morphology of Dictyostelium discoideumQ36197683
Centrin plays an essential role in microtubule severing during flagellar excision in Chlamydomonas reinhardtiiQ36233793
Three-dimensional structural characterization of centrosomes from early Drosophila embryosQ36235899
Characterization of two related Drosophila gamma-tubulin complexes that differ in their ability to nucleate microtubulesQ36255800
Stu2p: A microtubule-binding protein that is an essential component of the yeast spindle pole body.Q36275044
Dynein intermediate chain mediated dynein-dynactin interaction is required for interphase microtubule organization and centrosome replication and separation in DictyosteliumQ36313377
mini spindles: A gene encoding a conserved microtubule-associated protein required for the integrity of the mitotic spindle in DrosophilaQ36316666
Identification of XMAP215 as a microtubule-destabilizing factor in Xenopus egg extract by biochemical purificationQ36323454
Spindle orientation in Saccharomyces cerevisiae depends on the transport of microtubule ends along polarized actin cablesQ36323500
Drosophila EB1 is important for proper assembly, dynamics, and positioning of the mitotic spindleQ36323890
A role for centrin 3 in centrosome reproductionQ36327449
Cytoplasmic dynein participates in the centrosomal localization of the Golgi complexQ36531878
Centrosome positioning and directionality of cell movements.Q36573365
Role of dynactin in endocytic traffic: effects of dynamitin overexpression and colocalization with CLIP-170Q36952081
Overexpression of cytoplasmic dynein's globular head causes a collapse of the interphase microtubule network in DictyosteliumQ37381336
Yeast gene required for spindle pole body duplication: homology of its product with Ca2+-binding proteinsQ37392145
The microtubule plus end-tracking proteins mal3p and tip1p cooperate for cell-end targeting of interphase microtubulesQ38342879
EB1 reveals mobile microtubule nucleation sites in ArabidopsisQ38349273
Unusual centrosome cycle in Dictyostelium: correlation of dynamic behavior and structural changesQ38609648
Fission yeast ch-TOG/XMAP215 homologue Alp14 connects mitotic spindles with the kinetochore and is a component of the Mad2-dependent spindle checkpointQ39645373
The XMAP215 homologue Stu2 at yeast spindle pole bodies regulates microtubule dynamics and anchorageQ39958750
Molecular analysis of the cytosolic Dictyostelium gamma-tubulin complexQ40730817
Requirement of a centrosomal activity for cell cycle progression through G1 into S phaseQ40823744
Adenomatous polyposis coli (APC) protein moves along microtubules and concentrates at their growing ends in epithelial cellsQ40901818
Characterization of mammalian NIMA-related kinasesQ41138637
Protofilaments and rings, two conformations of the tubulin family conserved from bacterial FtsZ to alpha/beta and gamma tubulinQ41152833
The identification of mammalian centrosomal antigens using human autoimmune anticentrosome antiseraQ41787640
The spindle pole body component Spc97p interacts with the gamma-tubulin of Saccharomyces cerevisiae and functions in microtubule organization and spindle pole body duplicationQ41807611
Dynein motor regulation stabilizes interphase microtubule arrays and determines centrosome positionQ41986376
Mutational analysis of centrin: an EF-hand protein associated with three distinct contractile fibers in the basal body apparatus of ChlamydomonasQ42118557
Stu2p, the budding yeast member of the conserved Dis1/XMAP215 family of microtubule-associated proteins is a plus end-binding microtubule destabilizerQ42130009
A role for NIMA in the nuclear localization of cyclin B in Aspergillus nidulansQ42151770
A role for regulated binding of p150(Glued) to microtubule plus ends in organelle transportQ42248899
The Microtubule plus end-tracking protein EB1 is localized to the flagellar tip and basal bodies in Chlamydomonas reinhardtiiQ42452654
Adherens junctions inhibit asymmetric division in the Drosophila epitheliumQ42499987
The Cdc31p-binding protein Kar1p is a component of the half bridge of the yeast spindle pole bodyQ42771276
Cdc42, dynein, and dynactin regulate MTOC reorientation independent of Rho-regulated microtubule stabilizationQ42824851
Dynein binds to beta-catenin and may tether microtubules at adherens junctions.Q43754950
Msps/XMAP215 interacts with the centrosomal protein D-TACC to regulate microtubule behaviour.Q47070596
p93dis1, which is required for sister chromatid separation, is a novel microtubule and spindle pole body-associating protein phosphorylated at the Cdc2 target sitesQ48072526
XMAP215 is required for the microtubule-nucleating activity of centrosomesQ48853533
In vitro nucleation of microtubules from microtubule-organizing center prepared from cellular slime moldQ49026794
Kinetics and regulation of de novo centriole assembly. Implications for the mechanism of centriole duplication.Q52137805
Dynein and dynactin are localized to astral microtubules and at cortical sites in mitotic epithelial cells.Q52187841
Identification of gamma-tubulin, a new member of the tubulin superfamily encoded by mipA gene of Aspergillus nidulans.Q55059378
Reconstitution of Physiological Microtubule Dynamics Using Purified ComponentsQ57083346
Sequence and analysis of chromosome 2 of Dictyostelium discoideumQ57211173
The role of the proteins Kar9 and Myo2 in orienting the mitotic spindle of budding yeastQ58486711
Mutations in the APC tumour suppressor gene cause chromosomal instabilityQ62024148
Two loci required for cytoplasmic organization in early embryos of Caenorhabditis elegansQ70015784
Asymmetric loading of Kar9 onto spindle poles and microtubules ensures proper spindle alignmentQ73034919
Cell cycle-dependent localization of monoclonal antibodies raised against isolated Dictyostelium centrosomesQ73077261
Maltose-binding protein as a fusion tag for the localization and purification of cloned proteins in DictyosteliumQ73402821
Molecular linkage underlying microtubule orientation toward cortical sites in yeastQ73579757
Positioning of the mitotic spindle by a cortical-microtubule capture mechanismQ73579761
The interaction of TOGp with microtubules and tubulinQ73689032
Regulated Expression of the Centrosomal Protein DdCP224 Affects Microtubule Dynamics and Reveals Mechanisms for the Control of Supernumerary Centrosome NumberQ30480604
The Dictyostelium developmental cDNA project: generation and analysis of expressed sequence tags from the first-finger stage of development.Q30649535
Centrosomes enhance the fidelity of cytokinesis in vertebrates and are required for cell cycle progressionQ30662520
Hsp90 is a core centrosomal component and is required at different stages of the centrosome cycle in Drosophila and vertebratesQ30846862
Isolation of nucleation-competent centrosomes from Dictyostelium discoideumQ32034461
Centrosome-dependent exit of cytokinesis in animal cellsQ32062097
Gamma-tubulin complexes: size does matter.Q33719394
Dictyostelium discoideum: a promising centrosome model systemQ33781771
Microtubule-actomyosin interactions in cortical flow and cytokinesisQ33829499
Microtubule growth activates Rac1 to promote lamellipodial protrusion in fibroblastsQ33880071
Control of microtubule dynamics by the antagonistic activities of XMAP215 and XKCM1 in Xenopus egg extractsQ33885622
HEAT repeats associated with condensins, cohesins, and other complexes involved in chromosome-related functionsQ33922394
Microtubule "plus-end-tracking proteins": The end is just the beginningQ33947998
MOR1 is essential for organizing cortical microtubules in plants.Q33949237
Comparative structural, molecular, and functional aspects of the Dictyostelium discoideum centrosomeQ34044922
Regulating centrosomes by protein phosphorylation.Q34044967
The role of the centrosome in the development of malignant tumorsQ34044973
Managing the centrosome numbers game: from chaos to stability in cancer cell divisionQ34123299
The centrosome cycleQ34133654
Centrosome aberrations: cause or consequence of cancer progression?Q34157650
XMAP215 regulates microtubule dynamics through two distinct domains.Q34271357
Calcium-dependent assembly of centrin-G-protein complex in photoreceptor cellsQ34275982
In search of a function for centrinsQ34290900
In vitro reconstitution of centrosome assembly and function: the central role of gamma-tubulinQ34336909
Dynein at the cortexQ34495155
On the mechanism of cleavage furrow ingression in Dictyostelium.Q34593533
Characterization of a new gammaTuRC subunit with WD repeatsQ34813274
Loss of p53 and centrosome hyperamplification.Q34818333
Duplicating dangerously: linking centrosome duplication and aneuploidyQ34984911
Microtubule nucleation.Q35041122
Never say never. The NIMA-related protein kinases in mitotic controlQ35125628
Surfing on microtubule endsQ35125633
Dynamic microtubules in DictyosteliumQ35210309
Centrosomal microtubule plus end tracking proteins and their role in Dictyostelium cell dynamicsQ35210312
P304page(s)155-202
P577publication date2004-01-01
P1433published inInternational Review of CytologyQ2687019
P1476titleMolecular and functional analysis of the dictyostelium centrosome
P478volume241

Reverse relations

cites work (P2860)
Q42262033Aberrant spindle dynamics and cytokinesis in Dictyostelium discoideum cells that lack glycogen synthase kinase 3
Q27937452Acetylation of the SUN protein Mps3 by Eco1 regulates its function in nuclear organization.
Q42914663Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis
Q53160101CP55, a novel key component of centrosomal organization in Dictyostelium.
Q58577692Comparative Biology of Centrosomal Structures in Eukaryotes
Q30482048Dictyostelium Aurora kinase has properties of both Aurora A and Aurora B kinases
Q30475931Dictyostelium LIS1 is a centrosomal protein required for microtubule/cell cortex interactions, nucleus/centrosome linkage, and actin dynamics
Q43071913Dictyostelium discoideum CenB is a bona fide centrin essential for nuclear architecture and centrosome stability
Q30497516Dynamics of a novel centromeric histone variant CenH3 reveals the evolutionary ancestral timing of centromere biogenesis.
Q50504819Functional characterization of CP148, a novel key component for centrosome integrity in Dictyostelium.
Q47732262Identification and cell cycle-dependent localization of nine novel, genuine centrosomal components in Dictyostelium discoideum
Q61917728Nek2
Q38195121Nucleocytoplasmic protein translocation during mitosis in the social amoebozoan Dictyostelium discoideum
Q34388105RNG1 is a late marker of the apical polar ring in Toxoplasma gondii
Q41492003Spatiotemporal regulation of Ras activity provides directional sensing

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