Biochemical mechanisms for translational regulation in synaptic plasticity

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Biochemical mechanisms for translational regulation in synaptic plasticity is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1038/NRN1557
P698PubMed publication ID15550948

P50authorThomas DeverQ42882444
P2093author name stringEric Klann
P2860cites workCharacterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2alpha kinaseQ22010589
Influence of actinomycin D, a RNA synthesis inhibitor, on long-term potentiation in rat hippocampal neurons in vivo and in vitroQ24530139
Altered synaptic plasticity in a mouse model of fragile X mental retardationQ24530695
Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4EQ24533512
The mitogen-activated protein kinase signal-integrating kinase Mnk2 is a eukaryotic initiation factor 4E kinase with high levels of basal activity in mammalian cellsQ24551026
Phosphorylation of the cap-binding protein eukaryotic translation initiation factor 4E by protein kinase Mnk1 in vivoQ24554527
Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinasesQ24599204
A novel mTOR-regulated phosphorylation site in elongation factor 2 kinase modulates the activity of the kinase and its binding to calmodulinQ24599904
S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathwayQ24603083
Time-restricted role for dendritic activation of the mTOR-p70 S6K pathway in the induction of late-phase long-term potentiation in the CA1Q24630599
Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activationQ24657890
Facilitation of dendritic mRNA transport by CPEBQ24672622
eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translationQ27860920
Evidence that fragile X mental retardation protein is a negative regulator of translationQ28117211
EIF2AK3, encoding translation initiation factor 2-alpha kinase 3, is mutated in patients with Wolcott-Rallison syndromeQ28142981
New insights into fragile X syndrome: from molecules to neurobehaviorsQ28182730
Barentsz, a new component of the Staufen-containing ribonucleoprotein particles in mammalian cells, interacts with Staufen in an RNA-dependent mannerQ28185024
Phosphatidylinositol 3-Kinase Regulates the Induction of Long-Term Potentiation through Extracellular Signal-Related Kinase-Independent MechanismsQ28203054
Translational control by CPEB: a means to the endQ28204377
Subunits of the translation initiation factor eIF2B are mutant in leukoencephalopathy with vanishing white matterQ28204796
Internal ribosome entry sites in eukaryotic mRNA moleculesQ28205551
Phosphatidylinositol 3-kinase is required for the expression but not for the induction or the maintenance of long-term potentiation in the hippocampal CA1 regionQ28215948
The molecular basis of CaMKII function in synaptic and behavioural memoryQ28216850
A neuronal isoform of CPEB regulates local protein synthesis and stabilizes synapse-specific long-term facilitation in aplysiaQ28236378
Translational control by MAPK signaling in long-term synaptic plasticity and memoryQ28249953
Regulation of eukaryotic initiation factor eIF2B: glycogen synthase kinase-3 phosphorylates a conserved serine which undergoes dephosphorylation in response to insulinQ28262178
Regulation of elongation factor-2 by multisite phosphorylationQ28263254
Fragile X mental retardation protein: nucleocytoplasmic shuttling and association with somatodendritic ribosomesQ28303541
The fragile X mental retardation protein binds specifically to its mRNA via a purine quartet motifQ28348391
Heme-regulated eIF2alpha kinase (HRI) is required for translational regulation and survival of erythroid precursors in iron deficiencyQ28365535
The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreasQ28505821
Regulated translation initiation controls stress-induced gene expression in mammalian cellsQ28506388
Selective modulation of some forms of schaffer collateral-CA1 synaptic plasticity in mice with a disruption of the CPEB-1 geneQ28513435
Functional properties of phosphorylated elongation factor 2Q28572074
Metabotropic glutamate receptor activation regulates fragile x mental retardation protein and FMR1 mRNA localization differentially in dendrites and at synapsesQ28576233
Proliferation, but not growth, blocked by conditional deletion of 40S ribosomal protein S6Q28588241
Preservation of liver protein synthesis during dietary leucine deprivation occurs at the expense of skeletal muscle mass in mice deleted for eIF2 kinase GCN2.Q44948914
Regulation of dendritic protein synthesis by miniature synaptic events.Q44952134
Activation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression.Q44978632
5-HT stimulates eEF2 dephosphorylation in a rapamycin-sensitive manner in Aplysia neuritesQ45039976
NMDA receptor activation results in PKA- and ERK-dependent Mnk1 activation and increased eIF4E phosphorylation in hippocampal area CA1.Q45077701
Visualization of the distribution of autophosphorylated calcium/calmodulin-dependent protein kinase II after tetanic stimulation in the CA1 area of the hippocampus.Q46913435
Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and functionQ47071944
Maskin is a CPEB-associated factor that transiently interacts with elF-4E.Q47892275
Synaptic tagging: implications for late maintenance of hippocampal long-term potentiationQ48017067
Cellular and subcellular distributions of translation initiation, elongation and release factors in rat hippocampusQ48355949
RNA cargoes associating with FMRP reveal deficits in cellular functioning in Fmr1 null miceQ48392342
Spatial learning deficit in transgenic mice that conditionally over-express GSK-3beta in the brain but do not form tau filamentsQ48429540
Polyribosomes redistribute from dendritic shafts into spines with enlarged synapses during LTP in developing rat hippocampal slicesQ48519215
Polyribosomes at the base of dendritic spines of central nervous system neurons--their possible role in synapse construction and modificationQ48828018
Molecular characterization of the dendritic growth cone: regulated mRNA transport and local protein synthesisQ48847696
Global brain ischemia and reperfusion: modifications in eukaryotic initiation factors associated with inhibition of translation initiationQ48883920
Preferential localization of polyribosomes under the base of dendritic spines in granule cells of the dentate gyrus.Q48974772
Fragile X mouse: strain effects of knockout phenotype and evidence suggesting deficient amygdala function.Q51083891
Chemical stimulation of synaptosomes modulates alpha -Ca2+/calmodulin-dependent protein kinase II mRNA association to polysomes.Q52027387
NMDA receptor-mediated control of protein synthesis at developing synapses.Q52170470
An activity-dependent switch to cap-independent translation triggered by eIF4E dephosphorylationQ57042159
Long-term potentiation in the hippocampus of fragile X knockout miceQ57828486
Role for Rapid Dendritic Protein Synthesis in Hippocampal mGluR-Dependent Long-Term DepressionQ60141744
Long-term potentiation in dentate gyrus of the rat is inhibited by the phosphoinositide 3–kinase inhibitor, wortmanninQ62011091
Mechanism of elongation factor 2 (EF-2) inactivation upon phosphorylation. Phosphorylated EF-2 is unable to catalyze translocationQ69665326
Nerve and epidermal growth factor induce protein synthesis and eIF2B activation in PC12 cellsQ74263647
The fragile X mental retardation protein inhibits translation via interacting with mRNAQ28588486
Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survivalQ28593963
Gene-specific regulation by general translation factorsQ28611181
The molecular biology of memory storage: a dialogue between genes and synapsesQ29547845
Fragile X mental retardation protein targets G quartet mRNAs important for neuronal functionQ29616372
Kinesin transports RNA: isolation and characterization of an RNA-transporting granuleQ29618417
MAPK cascade signalling and synaptic plasticityQ29619955
Regulation of translation initiation by FRAP/mTORQ29620398
Serotonin activates S6 kinase in a rapamycin-sensitive manner in Aplysia synaptosomes.Q31840708
The fragile X mental retardation protein is required for type-I metabotropic glutamate receptor-dependent translation of PSD-95Q33717210
Ribosomal S6 kinase signaling and the control of translationQ33783527
The murine double-stranded RNA-dependent protein kinase PKR is required for resistance to vesicular stomatitis virus.Q33811639
A transient, neuron-wide form of CREB-mediated long-term facilitation can be stabilized at specific synapses by local protein synthesis.Q33878123
A rapamycin-sensitive signaling pathway contributes to long-term synaptic plasticity in the hippocampusQ33898132
Localization and translation of mRNA in dendrites and axonsQ33956250
A neuronal isoform of the aplysia CPEB has prion-like propertiesQ33974852
The brain-derived neurotrophic factor enhances synthesis of Arc in synaptoneurosomesQ34013346
A requirement for local protein synthesis in neurotrophin-induced hippocampal synaptic plasticityQ34062918
N-methyl-D-aspartate receptor signaling results in Aurora kinase-catalyzed CPEB phosphorylation and alpha CaMKII mRNA polyadenylation at synapsesQ34078959
The cytoplasmic polyadenylation element binding protein and polyadenylation of messenger RNA in Aplysia neuronsQ34164397
Protein synthesis at synaptic sites on dendritesQ34205382
The GCN2 eIF2alpha kinase is required for adaptation to amino acid deprivation in miceQ34286263
Phosphorylation of eukaryotic translation initiation factor 4E is critical for growthQ34323752
Requirement of a critical period of transcription for induction of a late phase of LTP.Q34332490
Synaptic tagging and long-term potentiationQ34415413
Cloning and characterization of a cDNA encoding a protein synthesis initiation factor-2alpha (eIF-2alpha) kinase from Drosophila melanogaster. Homology To yeast GCN2 protein kinaseQ34424980
Synapse-specific, long-term facilitation of aplysia sensory to motor synapses: a function for local protein synthesis in memory storageQ34452179
Does phosphorylation of the cap-binding protein eIF4E play a role in translation initiation?Q34992458
Regulation of transcription factors by neuronal activity.Q35014009
Synaptic tagging during synapse-specific long-term facilitation of Aplysia sensory-motor neuronsQ35057359
Two previously undescribed members of the mouse CPEB family of genes and their inducible expression in the principal cell layers of the hippocampusQ35234990
Mnk2 and Mnk1 are essential for constitutive and inducible phosphorylation of eukaryotic initiation factor 4E but not for cell growth or developmentQ35663786
Mitogen-activated protein kinases in synaptic plasticity and memory.Q35803116
RNA translation in axonsQ35912829
Regulation of antioxidant metabolism by translation initiation factor 2alphaQ36379914
N-methyl-D-aspartate receptor activation and visual activity induce elongation factor-2 phosphorylation in amphibian tecta: a role for N-methyl-D-aspartate receptors in controlling protein synthesis.Q36831686
Glutamate-dependent phosphorylation of elongation factor-2 and inhibition of protein synthesis in neurons.Q36857987
Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cellsQ37388595
The staufen/pumilio pathway is involved in Drosophila long-term memory.Q38357525
Eukaryotic protein synthesisQ39826645
Phosphorylation of eukaryotic initiation factor 4E markedly reduces its affinity for capped mRNA.Q40766564
Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infectionQ40863327
Cytoplasmic polyadenylation element binding protein-dependent protein synthesis is regulated by calcium/calmodulin-dependent protein kinase II.Q42462537
Regulation of eukaryotic initiation factor 4E phosphorylation in the nervous system of Aplysia californicaQ42490798
Adipose tissue reduction in mice lacking the translational inhibitor 4E-BP1.Q42511063
Phosphorylation of eIF4E attenuates its interaction with mRNA 5' cap analogs by electrostatic repulsion: intein-mediated protein ligation strategy to obtain phosphorylated proteinQ43166736
Brain ischemia and reperfusion activates the eukaryotic initiation factor 2alpha kinase, PERK.Q43627961
Dynamic visualization of local protein synthesis in hippocampal neuronsQ43631820
Mitogen-activated protein kinase regulates early phosphorylation and delayed expression of Ca2+/calmodulin-dependent protein kinase II in long-term potentiation.Q43732514
Brain-derived neurotrophic factor enhances neuronal translation by activating multiple initiation processes: comparison with the effects of insulinQ43733966
A role for a rat homolog of staufen in the transport of RNA to neuronal dendritesQ43799823
Phosphorylation and local presynaptic protein synthesis in calcium- and calcineurin-dependent induction of crayfish long-term facilitation.Q43799829
Expression of constitutively active CREB protein facilitates the late phase of long-term potentiation by enhancing synaptic captureQ43917165
The group I metabotropic glutamate receptor agonist (S)-3,5-dihydroxyphenylglycine induces a novel form of depotentiation in the CA1 region of the hippocampus.Q44185962
Localized synaptic potentiation by BDNF requires local protein synthesis in the developing axonQ44222201
Adenylyl cyclase-dependent form of chemical long-term potentiation triggers translational regulation at the elongation stepQ44306459
Activity-dependent regulation of dendritic synthesis and trafficking of AMPA receptorsQ44760632
An investigation into signal transduction mechanisms involved in insulin-induced long-term depression in the CA1 region of the hippocampusQ44804982
Performance in long-term memory tasks is augmented by a phosphorylated growth factor receptor fragmentQ44947595
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectsynaptic plasticityQ1551556
P304page(s)931-942
P577publication date2004-12-01
P1433published inNature Reviews NeuroscienceQ2108225
P1476titleBiochemical mechanisms for translational regulation in synaptic plasticity
P478volume5

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Q28583711Synaptic signaling by all-trans retinoic acid in homeostatic synaptic plasticity
Q39451309Synaptically localized transcriptional regulators in memory formation
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Q89934165Transcriptional signature of prion-induced neurotoxicity in a Drosophila model of transmissible mammalian prion disease
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Q38781395Translational control by eIF2α in neurons: Beyond the stress response
Q34768377Translational control of gene expression: a molecular switch for memory storage
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Q36737783Uncovering the mechanisms of estrogen effects on hippocampal function.
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Q35906366Xuefu Zhuyu decoction, a traditional Chinese medicine, provides neuroprotection in a rat model of traumatic brain injury via an anti-inflammatory pathway
Q35941480cFLIP is critical for oligodendrocyte protection from inflammation
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