Regulation of Proinflammatory Mediators via NF-κB and p38 MAPK-Dependent Mechanisms in RAW 264.7 Macrophages by Polyphenol Components Isolated from Korea Lonicera japonica THUNB.

scientific article

Regulation of Proinflammatory Mediators via NF-κB and p38 MAPK-Dependent Mechanisms in RAW 264.7 Macrophages by Polyphenol Components Isolated from Korea Lonicera japonica THUNB. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1155/2012/828521
P932PMC publication ID3352662
P698PubMed publication ID22611435
P5875ResearchGate publication ID225050796

P50authorSung Chul ShinQ118239274
P2093author name stringEun Hee Kim
Won Sup Lee
Jin A Kim
Arulkumar Nagappan
Do Hoon Lee
Gon Sup Kim
Hyeon-Soo Park
Sang-Rim Kang
Kwang-Il Park
Su Jin An
Hyon-Jong Chung
P2860cites workSelective expression of mitogen-inducible cyclooxygenase in macrophages stimulated with lipopolysaccharideQ67965056
Inactivation of phospholipase A2 by naturally occurring biflavonoid, ochnaflavoneQ72903708
The p38 mitogen-activated protein kinase is required for NF-kappaB-dependent gene expression. The role of TATA-binding protein (TBP)Q73083269
Anti-inflammatory effect of Lonicera japonica in proteinase-activated receptor 2-mediated paw edemaQ73126914
Anti-inflammatory effect of the aqueous extract from Lonicera japonica flower is related to inhibition of NF-kappaB activation through reducing I-kappaBalpha degradation in rat liverQ73294429
The role of p38 mitogen-activated protein kinase in IL-6 and IL-8 production from the TNF-alpha- or IL-1beta-stimulated rheumatoid synovial fibroblastsQ73323617
Specific inhibitors of p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways block inducible nitric oxide synthase and tumor necrosis factor accumulation in murine macrophages stimulated with lipopolysaccharide andQ74587899
Regulation of interleukin-1beta-induced interleukin-6 gene expression in human fibroblast-like synoviocytes by p38 mitogen-activated protein kinaseQ77229202
Down-regulation of iNOS and TNF-alpha expression by kaempferol via NF-kappaB inactivation in aged rat gingival tissuesQ79719544
A protein kinase involved in the regulation of inflammatory cytokine biosynthesisQ24311139
Phosphorylation meets ubiquitination: the control of NF-[kappa]B activityQ27860643
NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responsesQ27861101
NF-kappaB: a key role in inflammatory diseasesQ29617726
SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1Q29620495
Organization and regulation of mitogen-activated protein kinase signaling pathwaysQ33333640
Rapid and simple method for screening of natural antioxidants from Chinese herb Flos Lonicerae Japonicae by DPPH-HPLC-DAD-TOF/MS.Q33373389
Macrophage activation and programming and its role for macrophage function in glomerular inflammationQ33648878
Toll-like receptor 4 in CNS pathologiesQ34018705
The role of cytokines, chemokines, and adhesion molecules in the pathogenesis of idiopathic inflammatory myopathiesQ34108944
Suppressive Effect on Lipopolysaccharide‐Induced Proinflammatory Mediators by Citrus aurantium L. in Macrophage RAW 264.7 Cells via NF‐κB Signal PathwayQ34186808
Transcriptional and post-transcriptional control of gene expression in inflammationQ35009675
Inhibition of nuclear factor kappa B (NF-B): an emerging theme in anti-inflammatory therapiesQ35679402
The many paths to p38 mitogen-activated protein kinase activation in the immune systemQ36518938
Regulation of NF-kappaB signaling by decoy oligodeoxynucleotidesQ36573247
The role of nuclear factor-kappaB in inflammatory lung diseaseQ37778102
The naturally occurring biflavonoid, ochnaflavone, inhibits LPS-induced iNOS expression, which is mediated by ERK1/2 via NF-kappaB regulation, in RAW264.7 cellsQ38510870
The neuroprotective effects of Lonicera japonica THUNB. against hydrogen peroxide-induced apoptosis via phosphorylation of MAPKs and PI3K/Akt in SH-SY5Y cellsQ39607606
Luteolin isolated from the flowers of Lonicera japonica suppresses inflammatory mediator release by blocking NF-kappaB and MAPKs activation pathways in HMC-1 cellsQ39746551
Inhibitory effect of 3-caffeoyl-4-dicaffeoylquinic acid from Salicornia herbacea against phorbol ester-induced cyclooxygenase-2 expression in macrophagesQ39772030
Anti-inflammatory effects of ethyl acetate fraction from Melilotus suaveolens Ledeb on LPS-stimulated RAW 264.7 cells.Q39853683
Inhibition of LPS-induced iNOS, COX-2 and cytokines expression by poncirin through the NF-kappaB inactivation in RAW 264.7 macrophage cellsQ40040489
Nuclear factor kappa B is a molecular target for sulforaphane-mediated anti-inflammatory mechanisms.Q40798546
p38 MAPK and NF-kappa B collaborate to induce interleukin-6 gene expression and release. Evidence for a cytoprotective autocrine signaling pathway in a cardiac myocyte model systemQ41732350
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P921main subjectLonicera japonicaQ161083
polyphenolQ290439
NF-κBQ411114
P304page(s)828521
P577publication date2012-05-07
P1433published inEvidence-based Complementary and Alternative MedicineQ5418319
P1476titleRegulation of Proinflammatory Mediators via NF-κB and p38 MAPK-Dependent Mechanisms in RAW 264.7 Macrophages by Polyphenol Components Isolated from Korea Lonicera japonica THUNB.
P478volume2012

Reverse relations

cites work (P2860)
Q37507241Anti-Inflammatory Effects and Mechanisms of Fatsia polycarpa Hayata and Its Constituents
Q39156678Anti-inflammatory activities of an active fraction isolated from the root of Astragalus membranaceus in RAW 264.7 macrophages.
Q38166686Cancer Prevention and Therapy: Integrating Traditional Korean Medicine Into Modern Cancer Care
Q89698721Effects of Lonicera japonica extract on performance and blood biomarkers of inflammation and oxidative stress during perinatal period in dairy cow
Q34943633Frequency and pattern of Chinese herbal medicine prescriptions for urticaria in Taiwan during 2009: analysis of the national health insurance database
Q34981468Gelam honey attenuates carrageenan-induced rat paw inflammation via NF-κB pathway
Q91900592Honeysuckle extract relieves ovalbumin-induced allergic rhinitis by inhibiting AR-induced inflammation and autoimmunity
Q38922337Inhibitory Effects of Polydatin on Lipopolysaccharide-Stimulated RAW 264.7 Cells
Q35822089Lonicera japonica THUNB. Extract Inhibits Lipopolysaccharide-Stimulated Inflammatory Responses by Suppressing NF-κB Signaling in BV-2 Microglial Cells
Q26800086Lonicerae Japonicae Flos and Lonicerae Flos: A Systematic Pharmacology Review
Q37083753Modulation of immune function by polyphenols: possible contribution of epigenetic factors
Q42704497Naringin attenuates the development of carrageenan-induced acute lung inflammation through inhibition of NF-κb, STAT3 and pro-inflammatory mediators and enhancement of IκBα and anti-inflammatory cytokines.
Q33597907Polyphenolic compounds from Korean Lonicera japonica Thunb. induces apoptosis via AKT and caspase cascade activation in A549 cells
Q58617709The Immunomodulatory and Anti-Inflammatory Role of Polyphenols
Q35165162The screening research of anti-inflammatory bioactive markers from different flowering phases of Flos Lonicerae Japonicae