Aldosterone induces elastin production in cardiac fibroblasts through activation of insulin-like growth factor-I receptors in a mineralocorticoid receptor-independent manner

scientific article

Aldosterone induces elastin production in cardiac fibroblasts through activation of insulin-like growth factor-I receptors in a mineralocorticoid receptor-independent manner is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.2353/AJPATH.2007.070101
P932PMC publication ID1959490
P698PubMed publication ID17724138
P5875ResearchGate publication ID6116452

P2093author name stringPeter Liu
Aleksander Hinek
Kela Liu
Yanting Wang
Severa Bunda
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Transcriptional regulation of the elastin gene by insulin-like growth factor-I involves disruption of Sp1 binding. Evidence for the role of Rb in mediating Sp1 binding in aortic smooth muscle cellsQ72645576
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Early nongenomic events in aldosterone action in renal collecting duct cells: PKCalpha activation, mineralocorticoid receptor phosphorylation, and cross-talk with the genomic response.Q40564271
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67-kD elastin-binding protein is a protective "companion" of extracellular insoluble elastin and intracellular tropoelastinQ42953033
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Rapid stimulation of cyclic AMP production by aldosterone in rat inner medullary collecting ducts.Q44214383
Elafin-overexpressing mice have improved cardiac function after myocardial infarctionQ44704940
Transactivation of the insulin-like growth factor-I receptor by angiotensin II mediates downstream signaling from the angiotensin II type 1 receptor to phosphatidylinositol 3-kinaseQ44771641
Aldosterone potentiates angiotensin II-induced signaling in vascular smooth muscle cellsQ44907744
Mechanism for aldosterone potentiation of angiotensin II-stimulated rat arterial smooth muscle cell proliferationQ45012637
Elastin stabilizes an infarct and preserves ventricular functionQ45886823
beta-adrenergic stimulation of rat cardiac fibroblasts enhances induction of nitric-oxide synthase by interleukin-1beta via message stabilizationQ46096959
Aldosterone stimulates collagen gene expression and synthesis via activation of ERK1/2 in rat renal fibroblastsQ46640955
Nongenomic effects of aldosterone in the human heart: interaction with angiotensin II.Q46689526
SSR69071, an elastase inhibitor, reduces myocardial infarct size following ischemia-reperfusion injuryQ47173195
BNP-induced activation of cGMP in human cardiac fibroblasts: interactions with fibronectin and natriuretic peptide receptorsQ48417679
Altered collagen homeostasis in human aortic smooth muscle cells (HAoSMCs) induced by aldosterone.Q51800376
Insulin-like growth factor-I regulates transcription of the elastin gene through a putative retinoblastoma control element. A role for Sp3 acting as a repressor of elastin gene transcription.Q52551371
Nongenomic effects of aldosterone on intracellular Ca2+ in vascular smooth muscle cells.Q53856893
Steroid-protein conjugates. I. Preparation and characterization of conjugates of bovine serum albumin with testosterone and with cortisone.Q54136146
Limitation of Excessive Extracellular Matrix Turnover May Contribute to Survival Benefit of Spironolactone Therapy in Patients With Congestive Heart FailureQ57259661
The Role of the Glucocorticoid Receptor in Mineralocorticoid/Salt-Mediated Cardiac FibrosisQ58433468
Inhibition of oxytocin receptor function by direct binding of progesteroneQ59070216
The ductus arteriosus migratory smooth muscle cell phenotype processes tropoelastin to a 52-kDa product associated with impaired assembly of elastic laminaeQ70527414
Antifibrotic effects of spironolactone in preventing myocardial fibrosis in systemic arterial hypertensionQ70533705
Effects of angiotensin II and aldosterone on collagen gene expression and protein turnover in cardiac fibroblastsQ71284424
Determinants of cardiac fibrosis in experimental hypermineralocorticoid statesQ71552985
Prerequisite for cardiac aldosterone action. Mineralocorticoid receptor and 11 beta-hydroxysteroid dehydrogenase in the human heartQ71844423
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)809-819
P577publication date2007-09-01
P1433published inThe American Journal of PathologyQ4744259
P1476titleAldosterone induces elastin production in cardiac fibroblasts through activation of insulin-like growth factor-I receptors in a mineralocorticoid receptor-independent manner
P478volume171

Reverse relations

cites work (P2860)
Q36787705A cytokine axis regulates elastin formation and degradation
Q30319286Actions of aldosterone in the cardiovascular system: the good, the bad, and the ugly?
Q34392644Aldosterone Enhances IGF-I-Mediated Signaling and Biological Function in Vascular Smooth Muscle Cells
Q43036692Aldosterone and mineralocorticoid receptor antagonists modulate elastin and collagen deposition in human skin
Q41952334Aldosterone stimulates elastogenesis in cardiac fibroblasts via mineralocorticoid receptor-independent action involving the consecutive activation of Galpha13, c-Src, the insulin-like growth factor-I receptor, and phosphatidylinositol 3-kinase/Akt
Q38768295Circadian networks in human embryonic stem cell-derived cardiomyocytes
Q54982202Effects of Nitric Oxide on Voltage-Gated K⁺ Currents in Human Cardiac Fibroblasts through the Protein Kinase G and Protein Kinase A Pathways but Not through S-Nitrosylation.
Q46552895Emphysema in an adult with galactosialidosis linked to a defect in primary elastic fiber assembly
Q90655331Everolimus Rescues the Phenotype of Elastin Insufficiency in Patient Induced Pluripotent Stem Cell-Derived Vascular Smooth Muscle Cells
Q36999577Mineralocorticoid receptor agonists induce mouse aortic aneurysm formation and rupture in the presence of high salt
Q37298300Molecular mechanism underlying Akt activation in zinc-induced cardioprotection.
Q39024127Phytoestrogen, tanshinone IIA diminishes collagen deposition and stimulates new elastogenesis in cultures of human cardiac fibroblasts

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