New insights into the control of pulsatile GnRH release: the role of Kiss1/neurokinin B neurons

scientific article

New insights into the control of pulsatile GnRH release: the role of Kiss1/neurokinin B neurons is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3389/FENDO.2012.00048
P8608Fatcat IDrelease_6tgixo4b2rbffipnbokuh3y6lq
P932PMC publication ID3355984
P698PubMed publication ID22649420
P5875ResearchGate publication ID225079615

P2093author name stringVíctor M Navarro
P2860cites workHypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54Q24685744
The GPR54 gene as a regulator of pubertyQ28211950
Repetitive activation of hypothalamic G protein-coupled receptor 54 with intravenous pulses of kisspeptin in the juvenile monkey (Macaca mulatta) elicits a sustained train of gonadotropin-releasing hormone dischargesQ28281338
Minireview: kisspeptin/neurokinin B/dynorphin (KNDy) cells of the arcuate nucleus: a central node in the control of gonadotropin-releasing hormone secretionQ28283342
Mu-, delta- and kappa-opioid receptor-mediated inhibition of neurotransmitter release and adenylate cyclase activity in rat brain slices: studies with fentanyl isothiocyanateQ28284045
Neurokinin B stimulates GnRH release in the male monkey (Macaca mulatta) and is colocalized with kisspeptin in the arcuate nucleusQ28749270
Ultrastructural Evidence of Kisspeptin-Gonadotrophin-Releasing Hormone (GnRH) Interaction in the Median Eminence of Female Rats: Implication of Axo-Axonal Regulation of GnRH ReleaseQ29030172
Mechanisms underlying episodic gonadotropin-releasing hormone secretionQ30310866
Uncovering novel reproductive defects in neurokinin B receptor null mice: closing the gap between mice and men.Q30422142
Regulation of NKB pathways and their roles in the control of Kiss1 neurons in the arcuate nucleus of the male mouseQ30424215
Forebrain projections of arcuate neurokinin B neurons demonstrated by anterograde tract-tracing and monosodium glutamate lesions in the rat.Q30432921
Decreased expression of A-kinase anchoring protein 150 in GT1 neurons decreases neuron excitability and frequency of intrinsic gonadotropin-releasing hormone pulsesQ30433631
Kisspeptin/Gpr54-independent gonadotrophin-releasing hormone activity in Kiss1 and Gpr54 mutant miceQ30434006
Endogenous activation of metabotropic glutamate receptors modulates GABAergic transmission to gonadotropin-releasing hormone neurons and alters their firing rate: a possible local feedback circuitQ30437143
Nonclassical estrogen receptor alpha signaling mediates negative feedback in the female mouse reproductive axisQ30444265
Negative feedback regulation of the secretion and actions of gonadotropin-releasing hormone in malesQ32023459
Regulation of Ca2+-sensitive adenylyl cyclase in gonadotropin-releasing hormone neuronsQ32062068
Hypothalamic pathways linking energy balance and reproductionQ33345231
Kisspeptin signalling in the hypothalamic arcuate nucleus regulates GnRH pulse generator frequency in the ratQ33519061
Pulsatile gonadotropin-releasing hormone release from hypothalamic explants of male marmoset monkeys compared with male ratsQ33589483
Regulation of Kiss1 and dynorphin gene expression in the murine brain by classical and nonclassical estrogen receptor pathwaysQ33641423
Neurokinin 3 receptor immunoreactivity in the septal region, preoptic area and hypothalamus of the female sheep: colocalisation in neurokinin B cells of the arcuate nucleus but not in gonadotrophin-releasing hormone neurones.Q33652453
Neurokinin B acts via the neurokinin-3 receptor in the retrochiasmatic area to stimulate luteinizing hormone secretion in sheepQ34132446
Influence of age and 17beta-estradiol on kisspeptin, neurokinin B, and prodynorphin gene expression in the arcuate-median eminence of female rhesus macaquesQ34132527
The mammalian tachykinin ligand-receptor system: an emerging target for central neurological disordersQ34259043
Evidence that cells expressing luteinizing hormone-releasing hormone mRNA in the mouse are derived from progenitor cells in the olfactory placodeQ34314255
Origin of luteinizing hormone-releasing hormone neuronsQ34497621
TAC3 and TACR3 mutations in familial hypogonadotropic hypogonadism reveal a key role for Neurokinin B in the central control of reproductionQ34902985
Kisspeptin resets the hypothalamic GnRH clock in men.Q35001924
The relationship between pulsatile GnRH secretion and cAMP production in immortalized GnRH neuronsQ35055448
Ontogeny and mechanisms of action for the stimulatory effect of kisspeptin on gonadotropin-releasing hormone system of the rat.Q51804586
Distribution of cells containing mRNAs encoding substance P and neurokinin B in the rat central nervous system.Q52070173
Kisspeptin Activation of Gonadotropin Releasing Hormone Neurons and Regulation of KiSS-1 mRNA in the Male RatQ58684160
Central injection of senktide, an NK3 receptor agonist, or neuropeptide Y inhibits LH secretion and induces different patterns of Fos expression in the rat hypothalamusQ62073287
Pattern of gonadotropin-releasing hormone (GnRH) secretion leading up to ovulation in the ewe: existence of a preovulatory GnRH surgeQ67946927
Hypophysiotropic signal frequency and the functioning of the pituitary-ovarian system in the rhesus monkeyQ70433829
Hypothalamic multiunit activity and pulsatile luteinizing hormone release in the castrated male ratQ71795582
Suppressive effect of dynorphin-(1–13) on luteinizing hormone release in conscious castrated ratsQ72945294
Dual label in situ hybridization studies provide evidence that luteinizing hormone-releasing hormone neurons do not synthesize messenger ribonucleic acid for mu, kappa, or delta opiate receptorsQ73167204
Pulsatile gonadotropin-releasing hormone (GnRH) secretion is an inherent function of GnRH neurons, as revealed by the culture of medial olfactory placode obtained from embryonic ratsQ73473394
Decrease in gonadotropin-releasing hormone (GnRH) pulse frequency with aging in postmenopausal womenQ73866944
Detection of estrogen receptor-beta messenger ribonucleic acid and 125I-estrogen binding sites in luteinizing hormone-releasing hormone neurons of the rat brainQ74244393
Morphological evidence for direct interaction between kisspeptin and gonadotropin-releasing hormone neurons at the median eminence of the male goat: an immunoelectron microscopic studyQ82675106
Molecular properties of Kiss1 neurons in the arcuate nucleus of the mouseQ35417113
Evidence from the agonadal juvenile male rhesus monkey (Macaca mulatta) for the view that the action of neurokinin B to trigger gonadotropin-releasing hormone release is upstream from the kisspeptin receptorQ35613975
Sexual dimorphism of kisspeptin and neurokinin B immunoreactive neurons in the infundibular nucleus of aged men and womenQ35971752
Role of neurokinin B in the control of female puberty and its modulation by metabolic statusQ36595730
An increase in kisspeptin-54 release occurs with the pubertal increase in luteinizing hormone-releasing hormone-1 release in the stalk-median eminence of female rhesus monkeys in vivoQ36796635
Kisspeptin can stimulate gonadotropin-releasing hormone (GnRH) release by a direct action at GnRH nerve terminals.Q36796644
Generation and synchronization of gonadotropin-releasing hormone (GnRH) pulses: intrinsic properties of the GT1-1 GnRH neuronal cell lineQ36864480
Interactions between kisspeptin and neurokinin B in the control of GnRH secretion in the female rat.Q37174107
Calcium signaling and episodic secretion of gonadotropin-releasing hormone in hypothalamic neuronsQ37195474
Administration of connexin43 siRNA abolishes secretory pulse synchronization in GnRH clonal cell populationsQ37440702
Regulation of gonadotropin-releasing hormone secretion by kisspeptin/dynorphin/neurokinin B neurons in the arcuate nucleus of the mouseQ37475488
Neurobiological mechanisms underlying GnRH pulse generation by the hypothalamus.Q37800630
Neuroendocrine control by kisspeptins: role in metabolic regulation of fertilityQ37930959
Ion channel properties and episodic activity in isolated immortalized gonadotropin-releasing hormone (GnRH) neuronsQ41525897
Neurokinin B and dynorphin A in kisspeptin neurons of the arcuate nucleus participate in generation of periodic oscillation of neural activity driving pulsatile gonadotropin-releasing hormone secretion in the goat.Q42467752
Soluble factors guide gonadotropin-releasing hormone axonal targeting to the median eminenceQ42492685
Kisspeptin signaling is indispensable for neurokinin B, but not glutamate, stimulation of gonadotropin secretion in mice.Q43435526
Pubertal acceleration of pulsatile gonadotropin-releasing hormone release in male rats as revealed by microdialysisQ44253422
Presence of mu and kappa opioid receptor mRNAs in galanin but not in GnRH neurons in the female rat.Q44347036
Gonadotrophin-releasing hormone pulse generator activity in the hypothalamus of the goat.Q44871932
Kisspeptin neurons in the arcuate nucleus of the ewe express both dynorphin A and neurokinin B.Q44932139
Central and peripheral administration of kisspeptin-10 stimulates the hypothalamic-pituitary-gonadal axis.Q45120757
Suppression of vasoactive intestinal polypeptide in the suprachiasmatic nucleus leads to aging-like alterations in cAMP rhythms and activation of gonadotropin-releasing hormone neurons.Q45213369
Anatomical location of mature GnRH neurons corresponds with their birthdate in the developing mouseQ46134675
Differential regulation of KiSS-1 mRNA expression by sex steroids in the brain of the male mouseQ46438750
Regulation of Kiss1 gene expression in the brain of the female mouse.Q46513180
Morphologic evidence that neurokinin B modulates gonadotropin-releasing hormone secretion via neurokinin 3 receptors in the rat median eminenceQ46605330
Menopausal increases in pulsatile gonadotropin-releasing hormone release in a nonhuman primate (Macaca mulatta).Q47254539
A role for kisspeptins in the regulation of gonadotropin secretion in the mouse.Q47289867
The KiSS-1 receptor GPR54 is essential for the development of the murine reproductive systemQ47346849
Aging alters the rhythmic expression of vasoactive intestinal polypeptide mRNA but not arginine vasopressin mRNA in the suprachiasmatic nuclei of female rats.Q48009423
Effect of time after castration on secretion of LHRH and LH in the ram.Q48137638
Intracellular Ca(2+) oscillations in luteinizing hormone-releasing hormone neurons derived from the embryonic olfactory placode of the rhesus monkey.Q48162745
Hypertrophy and increased kisspeptin gene expression in the hypothalamic infundibular nucleus of postmenopausal women and ovariectomized monkeysQ48174465
Gonadotrophin-releasing hormone (GnRH) exerts stimulatory effects on GnRH neurons in intact adult male and female miceQ48361185
The effects of neurokinin B upon gonadotrophin release in male rodents.Q48361192
Coexpression of dynorphin and neurokinin B immunoreactivity in the rat hypothalamus: Morphologic evidence of interrelated function within the arcuate nucleusQ48443918
Pulsatile secretion of gonadotropin-releasing hormone by rat hypothalamic explants without cell bodies of GnRH neurons [corrected]Q48591412
Luteinizing hormone-releasing hormone release during the rat estrous cycle and after ovariectomy, as estimated with push-pull cannulaeQ48880456
Profiling neurotransmitter receptor expression in mouse gonadotropin-releasing hormone neurons using green fluorescent protein-promoter transgenics and microarraysQ48924425
In situ hybridization analysis of the distribution of neurokinin-3 mRNA in the rat central nervous systemQ48939897
β-Endorphin and dynorphin control serum luteinizing hormone level in immature female ratsQ49129904
Developmental changes in hypothalamic Kiss1 expression during activation of the pulsatile release of luteinising hormone in maturing ewe lambsQ49160421
Activation of gonadotropin-releasing hormone neurons by kisspeptin as a neuroendocrine switch for the onset of puberty.Q50745717
The inhibitory effects of neurokinin B on GnRH pulse generator frequency in the female rat.Q51385117
Projections of arcuate nucleus and rostral periventricular kisspeptin neurons in the adult female mouse brain.Q51476822
P304page(s)48
P577publication date2012-04-02
P1433published inFrontiers in EndocrinologyQ27723680
P1476titleNew insights into the control of pulsatile GnRH release: the role of Kiss1/neurokinin B neurons
P478volume3