Serum and cellular ribavirin pharmacokinetic and concentration-effect analysis in HCV patients receiving sofosbuvir plus ribavirin

scientific article

Serum and cellular ribavirin pharmacokinetic and concentration-effect analysis in HCV patients receiving sofosbuvir plus ribavirin is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/JAC/DKV122
P932PMC publication ID4542804
P698PubMed publication ID25971261

P2093author name stringLane R Bushman
Eric G Meissner
John G McHutchison
Shyamasundaran Kottilil
Pamela Wolfe
Jennifer J Kiser
Joseph E Rower
Anu Osinusi
Zayani Sims
Leah C Jimmerson
Tess Petersen
P2860cites workA more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study GroupQ29614889
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IFNL4-ΔG genotype is associated with slower viral clearance in hepatitis C, genotype-1 patients treated with sofosbuvir and ribavirinQ33596086
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Mechanism of action of ribavirin in the combination treatment of chronic HCV infectionQ34618481
Sofosbuvir and ribavirin for hepatitis C genotype 1 in patients with unfavorable treatment characteristics: a randomized clinical trialQ34624732
Variants in the ITPA gene protect against ribavirin-induced hemolytic anemia and decrease the need for ribavirin dose reductionQ34913385
Measurement of intracellular ribavirin mono-, di- and triphosphate using solid phase extraction and LC-MS/MS quantificationQ34979638
Population pharmacokinetic modeling of plasma and intracellular ribavirin concentrations in patients with chronic hepatitis C virus infectionQ35169059
Pharmacokinetics of ribavirin in patients with hepatitis C virusQ35648745
Population pharmacokinetics and pharmacodynamics of ribavirin in patients with chronic hepatitis C genotype 1 infectionQ36065593
Optimum ribavirin exposure overcomes racial disparity in efficacy of peginterferon and ribavirin treatment for hepatitis C genotype 1.Q37032096
Ribavirin for chronic hepatitis C: and the mystery goes on.Q37811184
Development and validation of a dried blood spot assay for the quantification of ribavirin using liquid chromatography coupled to mass spectrometryQ38256679
Pharmacokinetics and absolute bioavailability of ribavirin in healthy volunteers as determined by stable-isotope methodology.Q39471947
ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C.Q39920642
Inosine triphosphate protects against ribavirin-induced adenosine triphosphate loss by adenylosuccinate synthase functionQ39965118
Sofosbuvir and ribavirin prevent recurrence of HCV infection after liver transplantation: an open-label studyQ41724402
Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised studyQ42202756
ABT-450/r-ombitasvir and dasabuvir with ribavirin for hepatitis C with cirrhosisQ42225140
Retreatment of HCV with ABT-450/r-ombitasvir and dasabuvir with ribavirinQ42225545
Efficacy of an interferon- and ribavirin-free regimen of daclatasvir, asunaprevir, and BMS-791325 in treatment-naive patients with HCV genotype 1 infectionQ42258200
Ribavirin pharmacokinetics in renal and liver transplant patients: evidence that it depends on renal functionQ42982324
Dosage of ribavirin in patients with hepatitis C should be based on renal function: a population pharmacokinetic analysis.Q44228676
Marked elevation of erythrocyte ribavirin levels in interferon and ribavirin-induced anemiaQ44832671
The metabolism of ribavirin in erythrocytes and nucleated cellsQ46071227
Development and validation of a useful HPLC-UV method for quantification of total and phosphorylated-ribavirin in blood and erythrocytes of HCV+ patients.Q50552379
Inosine triphosphatase polymorphisms and ribavirin pharmacokinetics as determinants of ribavirin-associate anemia in patients receiving standard anti-HCV treatment.Q50553037
Pharmacokinetics, safety, and tolerability of ribavirin in hemodialysis-dependent patients.Q50554702
Blood ribavirin concentration in high-dose ribavirin for adenovirus-induced haemorrhagic cystitis - a case report.Q50569359
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectpharmacokineticsQ323936
ribavirinQ421862
sofosbuvirQ2502747
P1104number of pages8
P304page(s)2322-2329
P577publication date2015-05-13
P1433published inJournal of Antimicrobial ChemotherapyQ6294770
P1476titleSerum and cellular ribavirin pharmacokinetic and concentration-effect analysis in HCV patients receiving sofosbuvir plus ribavirin
P478volume70

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cites work (P2860)
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Q40385212Variant Inosine Triphosphatase Phenotypes Are Associated With Increased Ribavirin Triphosphate Levels