Prognostic value of urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitors PAI-1 and PAI-2 in breast carcinomas

scientific article

Prognostic value of urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitors PAI-1 and PAI-2 in breast carcinomas is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/BJC.1994.74
P932PMC publication ID1968685
P698PubMed publication ID8297742
P5875ResearchGate publication ID14901041

P2093author name stringMartin PM
Spyratos F
Gentile A
Bouchet C
Hacène K
Oglobine J
P2860cites workProtein and messenger RNA levels of plasminogen activators and inhibitors analyzed in 22 human tumor cell linesQ63915567
Plasminogen activator system in human breast cancerQ67743622
The plasminogen activation system in human colon cancer: messenger RNA for the inhibitor PAI-1 is located in endothelial cells in the tumor stromaQ67919702
Urokinase-plasminogen activator, a new and independent prognostic marker in breast cancerQ68357717
Increase of urokinase-type plasminogen activator gene expression in human lung and breast carcinomasQ68998787
ISMOD: an all-subsets regression program for generalized linear models. I. Statistical and computational backgroundQ69055553
Plasminogen activators and tumor development in the human colon: activity levels in normal mucosa, adenomatous polyps, and adenocarcinomasQ69204552
Plasminogen activator inhibitor 1 and plasminogen activator inhibitor 2 in various disease statesQ70386474
Urokinase (uPA) and its inhibitor PAI-1 are strong and independent prognostic factors in node-negative breast cancerQ70565913
Histological grading and prognosis in breast cancer; a study of 1409 cases of which 359 have been followed for 15 yearsQ24680218
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingQ25938984
Prognostic value of urokinase-type plasminogen activator in 671 primary breast cancer patientsQ33190800
Synthesis of fibrinolytic activator and inhibitor by endothelial cellsQ35051369
Relationship between cathepsin D, urokinase, and plasminogen activator inhibitors in malignant vs benign breast tumoursQ35993235
Plasminogen activators, tissue degradation, and cancerQ39476382
The relevance of plasminogen activators to neoplastic growth. A review of recent literature.Q39526019
Do proteases play a role in cancer invasion and metastasis?Q39669635
Receptor-mediated internalization and degradation of urokinase is caused by its specific inhibitor PAI-1.Q41206436
Role of the urokinase receptor in facilitating extracellular matrix invasion by cultured colon cancerQ41674938
Plasminogen activator inhibitor 1 in human carcinoma tissuesQ41679028
Urokinase-type plasminogen activator is expressed in stromal cells and its receptor in cancer cells at invasive foci in human colon adenocarcinomasQ42131114
Type-1 plasminogen activator inhibitor in human breast carcinomasQ43624221
Multiparametric Prognostic Evaluation of Biological Factors in Primary Breast CancerQ44050631
Clinical relevance of the urokinase-type and tissue-type plasminogen activators and of their type 1 inhibitor in breast cancerQ44212210
ISMOD: an all-subsets regression program for generalized linear models. II. Program guide and examplesQ44718325
Breast cancer prognostic factors: evaluation guidelines.Q55052359
Biological and clinical relevance of the urokinase-type plasminogen activator (uPA) in breast cancerQ59287828
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectplasminogenQ107129060
P304page(s)398-405
P577publication date1994-02-01
P1433published inBritish Journal of CancerQ326309
P1476titlePrognostic value of urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitors PAI-1 and PAI-2 in breast carcinomas
P478volume69

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cites work (P2860)
Q44439079A High Cytosol Value of Urokinase-Type Plasminogen Activator (uPA) May Be Predictive of Early Relapse in Primary Breast Cancer
Q35196548Angiogenesis and antiangiogenic strategies in pancreatic cancer
Q60907892Association of uPA and PAI-1 tumor levels and 4G/5G variants of PAI-1 gene with disease outcome in luminal HER2-negative node-negative breast cancer patients treated with adjuvant endocrine therapy
Q42522659Blood and tissue fibrinolytic profiles in patients with colorectal carcinoma.
Q34033291Can axillary dissection be avoided by improved molecular biological diagnosis?
Q36620181Cathepsin-D, urokinase plasminogen activator and type-1 plasminogen activator inhibitor in early breast cancer: an immunohistochemical study of prognostic value and relations to tenascin-C and other factors
Q35745390Cellular distribution and clinical value of urokinase-type plasminogen activator, its receptor, and plasminogen activator inhibitor-2 in esophageal squamous cell carcinoma
Q35616321Chemical strategies for activity-based proteomics
Q71089140Combined overexpression of urokinase, urokinase receptor, and plasminogen activator inhibitor-1 is associated with breast cancer progression: an immunohistochemical comparison of normal, benign, and malignant breast tissues
Q36421968Contribution of plasminogen activators and their inhibitors to the survival prognosis of patients with Dukes' stage B and C colorectal cancer
Q73515400Correlation of tissue and blood plasminogen activation system in breast cancer
Q36291662Development of a new metastatic human breast carcinoma xenograft line
Q36622861Differential regulation of cell proliferation and protease secretion by epidermal growth factor and amphiregulin in tumoral versus normal breast epithelial cells
Q37203214Down-regulation of SerpinB2 is associated with gefitinib resistance in non-small cell lung cancer and enhances invadopodia-like structure protrusions
Q73025879Elevations of tissue-type plasminogen activator and differential expression of urokinase-type plasminogen activator in diseased aorta
Q24533487Enzyme activity profiles of the secreted and membrane proteome that depict cancer cell invasiveness
Q36840119Expression of urokinase-type plasminogen activator (uPA) and its inhibitor PAI-1 in benign, borderline, malignant primary and metastatic ovarian tumors
Q36115751External quality assessment of trans-European multicentre antigen determinations (enzyme-linked immunosorbent assay) of urokinase-type plasminogen activator (uPA) and its type 1 inhibitor (PAI-1) in human breast cancer tissue extracts
Q40972502Genetic alterations in breast cancer.
Q53318958High tumor tissue concentration of plasminogen activator inhibitor 2 (PAI-2) is an independent marker for shorter progression-free survival in patients with early stage endometrial cancer.
Q53671085Impact of patient age on the outcome of primary breast carcinoma.
Q39712414In vitro inhibition of human malignant brain tumour cell line proliferation by anti-urokinase-type plasminogen activator monoclonal antibodies
Q47344852Increase of a urokinase receptor-related low-molecular-weight molecule in colorectal adenocarcinomas
Q71835777Influence of the extraction procedure on plasminogen activator inhibitor-2 (PAI-2) and urokinase receptor (uPAR) assays in breast cancer tissues
Q36641395Inhibition of apoptosis in human tumour cells by the tumour-associated serpin, SCC antigen-1.
Q78053624Invasion marker PAI-1 remains a strong prognostic factor after long-term follow-up both for primary breast cancer and following first relapse
Q47251534Larger and more invasive colorectal carcinoma contains larger amounts of plasminogen activator inhibitor type 1 and its relative ratio over urokinase receptor correlates well with tumor size
Q44611664Limited Prognostic Value of c-erbB-2 Compared to uPA and PAI-1 in Primary Breast Carcinoma
Q77540117Macrophage role in the anti-prostate cancer response to one class of antiangiogenic agents
Q53654445MiR-10a and miR-181c regulate collagen type I generation in hypertrophic scars by targeting PAI-1 and uPA.
Q33743421Modelling pulmonary microthrombosis coupled to metastasis: distinct effects of thrombogenesis on tumorigenesis
Q33922875New paradigms for the treatment of cancer: the role of anti-angiogenesis agents
Q34284270Node-Negative Breast Cancer: Which Patients Should Be Treated?
Q41062519Nutrition and breast cancer risk: can an effect via insulin resistance be demonstrated?
Q35980584Organ Specific Tumor Markers: What's New?
Q35495620Peroxisome Proliferator-Activated Receptor-γ Ligands Alter Breast Cancer Cell Motility through Modulation of the Plasminogen Activator System
Q47725947Physiological and pathological changes of plasma urokinase-type plasminogen activator, plasminogen activator inhibitor-1, and urokinase-type plasminogen activator receptor levels in healthy females and breast cancer patients
Q41100535Plasminogen activation on tumor cell surface and its involvement in human leukemia.
Q36430997Plasminogen activator inhibitor type 2 in breast cancer.
Q36430945Plasminogen activator inhibitor-1 (PAI-1) is not related to response to neoadjuvant chemotherapy in breast cancer
Q43760328Plasminogen activator inhibitor-1 as a measure of vascular remodelling in breast cancer
Q42937214Plasminogen activator system, vascular endothelial growth factor, and colorectal cancer progression
Q24794845Prognostic molecular markers in early breast cancer
Q36292147Prognostic significance of urokinase-type plasminogen activator and plasminogen activator inhibitor-1 in primary breast cancer.
Q71089115Prognostic value of the plasminogen activation system in patients with gastric carcinoma
Q36617900Prognostic value of uPA and p53 accumulation measured by quantitative biochemical assays in 1245 primary breast cancer patients: a multicentre study.
Q36292537Prognostic value of urokinase plasminogen activator in primary breast carcinoma: comparison of two immunoassay methods
Q33838161Proteases in gastrointestinal neoplastic diseases
Q42095382Proteolysis in human breast and colorectal cancer
Q33918458Proteolysis in human breast cancer
Q64950341Quality control of immunohistochemical evaluation of tumour-associated plasminogen activators and related components. European BIOMED-1 Concerted Action on Clinical Relevance of Proteases in Tumour Invasion and Metastasis.
Q37189305Revisiting the biological roles of PAI2 (SERPINB2) in cancer
Q36617844Risk-group discrimination in node-negative breast cancer using invasion and proliferation markers: 6-year median follow-up
Q36114916Significance of plasminogen activator inhibitor 2 as a prognostic marker in primary lung cancer: association of decreased plasminogen activator inhibitor 2 with lymph node metastasis
Q22009110Suppression of breast cancer growth and metastasis by a serpin myoepithelium-derived serine proteinase inhibitor expressed in the mammary myoepithelial cells
Q41547351The biochemistry of cancer dissemination
Q33634208The plasmin cascade and matrix metalloproteinases in non-small cell lung cancer
Q40934291The plasminogen activation system in tumour invasion and metastasis
Q40573725The prognostic value of the soluble urokinase-type plasminogen activator receptor (s-uPAR) in plasma of breast cancer patients with and without metastatic disease
Q34165118The role and regulation of urokinase-type plasminogen activator receptor gene expression in cancer invasion and metastasis
Q33538432The urokinase plasminogen activator system as a target for prognostic studies in breast cancer
Q41522331The urokinase-type plasminogen activator system in cancer metastasis: A review
Q73793888The urokinase-type plasminogen activator system in resected non-small-cell lung cancer. Rotterdam Oncology Thoracic Study Group
Q47718780Tissue extraction procedures for investigation of urokinase plasminogen activator (uPA) and its inhibitors PAI-1 and PAI-2 in human breast carcinomas
Q73645160Topological localization of plasminogen activator inhibitor type 2
Q36295115Transforming growth factor beta 1 and sodium butyrate differentially modulate urokinase plasminogen activator and plasminogen activator inhibitor-1 in human breast normal and cancer cells
Q33676610Urokinase plasminogen activator: a prognostic marker in multiple types of cancer
Q73503042Urokinase-type plasminogen activator receptor in gastric cancer: tissue expression and prognostic role
Q33779244microRNA-200c/141 upregulates SerpinB2 to promote breast cancer cell metastasis and reduce patient survival
Q35580701uPA and PAI-1 as biomarkers in breast cancer: validated for clinical use in level-of-evidence-1 studies

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