scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1030213338 |
P356 | DOI | 10.1038/BJC.1991.10 |
P932 | PMC publication ID | 1971657 |
P698 | PubMed publication ID | 1989664 |
P5875 | ResearchGate publication ID | 21165674 |
P2093 | author name string | F Y Lee | |
P2860 | cites work | Some studies of the active intermediates formed in the microsomal metabolism of cyclophosphamide and isophosphamide | Q69733875 |
Glutathione and glutathione transferase levels in mouse granulocytes following cyclophosphamide administration | Q69989393 | ||
Altered mouse bone marrow glutathione and glutathione transferase levels in response to cytotoxins | Q70070358 | ||
Comparative in vitro cytotoxicity of cyclophosphamide, its major active metabolites and the new oxazaphosphorine ASTA Z 7557 (INN mafosfamide) | Q70589430 | ||
Role of aldehyde dehydrogenase in cyclophosphamide-resistant L1210 leukemia | Q70641051 | ||
Does acrolein contribute to the cytotoxicity of cyclophosphamide? | Q70730277 | ||
Role of glutathione in the metabolism-dependent toxicity and chemotherapy of cyclophosphamide | Q70866970 | ||
Cytotoxicity and DNA cross-linking activity of 4-sulfidocyclophosphamides in mouse leukemia cells in vitro | Q71507575 | ||
Factors influencing the quantitative estimation of the in vivo survival of cells from solid tumors | Q72296540 | ||
Cell subpopulations dispersed from solid tumours and separated by centrifugal elutriation | Q36045196 | ||
NMR spectroscopic studies of intermediary metabolites of cyclophosphamide. A comprehensive kinetic analysis of the interconversion of cis- and trans-4-hydroxycyclophosphamide with aldophosphamide and the concomitant partitioning of aldophosphamide b | Q38581308 | ||
Redox properties and rate constants in free-radical mediated damage | Q39668593 | ||
The roles of intracellular glutathione in antineoplastic chemotherapy | Q39743733 | ||
Glutathione metabolism as a determinant of therapeutic efficacy: a review | Q40184201 | ||
Effect of glutathione depletion by L-buthionine sulfoximine on the cytotoxicity of cyclophosphamide in single and fractionated doses to EMT6/SF mouse tumors and bone marrow. | Q46151273 | ||
Heterogeneity of glutathione content in human ovarian cancer. | Q54343380 | ||
Isolation and mass spectral identification of blood metabolities of cyclophosphamide: Evidence for phosphoramide mustard as the biologically active metabolite | Q66931110 | ||
An experimental and analytical study of oxygen depletion in stirred cell suspensions | Q67260659 | ||
Comparative pharmacologic study in vitro and in vivo with cyclophosphamide (NSC-26271), cyclophosphamide metabolites, and plain nitrogen mustard compounds | Q67796446 | ||
The problem of oncostatic specificity of cyclophosphamide (NSC-26271): Studies on reactions that control the alkylating and cytotoxic activity | Q67796451 | ||
Glutathione as a determinant of cellular response to doxorubicin | Q68297845 | ||
Glutathione depletion as a determinant of sensitivity of human leukemia cells to cyclophosphamide | Q68737138 | ||
A proposed mechanism of resistance to cyclophosphamide and phosphoramide mustard in a Yoshida cell line in vitro | Q69588122 | ||
Inhibition of the protective effect of cyclophosphamide by pre-treatment with buthionine sulfoximine | Q69592507 | ||
Effect of thiol manipulation on chemopotentiation by nitroimidazoles | Q69600034 | ||
Activation mechanisms of mafosfamide and the role of thiols in cyclophosphamide metabolism | Q69729345 | ||
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 45-50 | |
P577 | publication date | 1991-01-01 | |
P1433 | published in | British Journal of Cancer | Q326309 |
P1476 | title | Glutathione diminishes the anti-tumour activity of 4-hydroperoxycyclophosphamide by stabilising its spontaneous breakdown to alkylating metabolites | |
P478 | volume | 63 |
Q42585422 | Acacia Senegal gum exudate offers protection against cyclophosphamide-induced urinary bladder cytotoxicity |
Q33421128 | Analysis of cyclophosphamide and five metabolites from human plasma using liquid chromatography-mass spectrometry and gas chromatography-nitrogen-phosphorus detection |
Q36289384 | Clinical pharmacokinetics of cyclophosphamide |
Q35994192 | Cyclophosphamide decreases O6-alkylguanine-DNA alkyltransferase activity in peripheral lymphocytes of patients undergoing bone marrow transplantation |
Q35994324 | DNA cell cycle distribution and glutathione (GSH) content according to circadian stage in bone marrow of cancer patients |
Q41017938 | Dependence of aldehyde dehydrogenase-mediated oxazaphosphorine resistance on soluble thiols: importance of thiol interactions with the secondary metabolite acrolein |
Q70558151 | Development of a model of melphalan-induced gastrointestinal toxicity in mice |
Q73850202 | Inhibitors of glutathione S-transferases as therapeutic agents |
Q33954656 | Interaction of oxazaphosphorines with multidrug resistance-associated protein 4 (MRP4). |
Q42542528 | Mixed effects of 2,6-dithiopurine against cyclophosphamide mediated bladder and lung toxicity in mice |
Q34113899 | Oxazaphosphorines: new therapeutic strategies for an old class of drugs |
Q58789353 | The effect of busulphan on the pharmacokinetics of cyclophosphamide and its 4-hydroxy metabolite: time interval influence on therapeutic efficacy and therapy-related toxicity |
Q73879207 | Tumor cell heterogeneity: impact on mechanisms of therapeutic drug resistance |