| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/J.JINORGBIO.2004.11.006 |
| P698 | PubMed publication ID | 15598487 |
| P2093 | author name string | Gonzalo Gonzalez | |
| Marie-Alda Gilles-Gonzalez | |||
| P433 | issue | 1 | |
| P921 | main subject | hypothesis | Q41719 |
| P304 | page(s) | 1-22 | |
| P577 | publication date | 2005-01-01 | |
| P1433 | published in | Journal of Inorganic Biochemistry | Q3186919 |
| P1476 | title | Heme-based sensors: defining characteristics, recent developments, and regulatory hypotheses | |
| P478 | volume | 99 |
| Q27652745 | 2.3 A X-ray structure of the heme-bound GAF domain of sensory histidine kinase DosT of Mycobacterium tuberculosis |
| Q90559047 | A Heme Propionate Staples the Structure of Cytochrome c for Methionine Ligation to the Heme Iron |
| Q54441398 | A haem cofactor is required for redox and light signalling by the AppA protein of Rhodobacter sphaeroides. |
| Q30385980 | A heme-binding domain controls regulation of ATP-dependent potassium channels. |
| Q36606079 | A model for tetrapyrrole synthesis as the primary mechanism for plastid-to-nucleus signaling during chloroplast biogenesis |
| Q41337613 | A novel heme-regulatory motif mediates heme-dependent degradation of the circadian factor period 2. |
| Q21283956 | A phylogenomic profile of globins |
| Q82038144 | Acidic pH conditions induce dissociation of the haem from the protein and destabilise the catalase isolated from Aspergillus terreus |
| Q39183460 | An oxidative N-demethylase reveals PAS transition from ubiquitous sensor to enzyme |
| Q37958044 | Bacterial adaptation of respiration from oxic to microoxic and anoxic conditions: redox control |
| Q38636638 | Bacterial heme-based sensors of nitric oxide |
| Q38058711 | Bacterial sensor kinases using Fe-S cluster binding PAS or GAF domains for O2 sensing |
| Q34131504 | Behavioral responses to hypoxia in Drosophila larvae are mediated by atypical soluble guanylyl cyclases |
| Q37955498 | Biogenesis of cbb(3)-type cytochrome c oxidase in Rhodobacter capsulatus |
| Q37972853 | CO metabolism, sensing, and signaling |
| Q47637990 | Carbon monoxide binding to the heme group at the dimeric interface modulates structure and copper accessibility in the Cu,Zn superoxide dismutase from Haemophilus ducreyi: in silico and in vitro evidences |
| Q24650777 | Carbon monoxide, reactive oxygen signaling, and oxidative stress |
| Q85067308 | Catalysis and oxygen binding of Ec DOS: a haem-based oxygen-sensor enzyme from Escherichia coli |
| Q53093276 | Catalytic enhancement of the heme-based oxygen-sensing phosphodiesterase EcDOS by hydrogen sulfide is caused by changes in heme coordination structure. |
| Q27652615 | Changes in Quaternary Structure in the Signaling Mechanisms of PAS Domains † , ‡ |
| Q46959090 | Characterization of a globin-coupled oxygen sensor with a gene-regulating function |
| Q38121347 | Chemical foundations of hydrogen sulfide biology |
| Q36564879 | Concepts and approaches towards understanding the cellular redox proteome |
| Q50472921 | Conformational analysis of the blue-light sensing protein YtvA reveals a competitive interface for LOV-LOV dimerization and interdomain interactions |
| Q38288105 | Coordination of diatomic ligands to heme: simply CO. |
| Q54440632 | Critical role of the heme axial ligand, Met95, in locking catalysis of the phosphodiesterase from Escherichia coli (Ec DOS) toward Cyclic diGMP. |
| Q47586927 | DNA binding by an imidazole-sensing CooA variant is dependent on the heme redox state |
| Q27676058 | Development of Inhibitors of the PAS-B Domain of the HIF-2α Transcription Factor |
| Q34947481 | DiGeorge critical region 8 (DGCR8) is a double-cysteine-ligated heme protein |
| Q33243835 | Differential activation of Escherichia coli chemoreceptors by blue-light stimuli |
| Q33266991 | Differential sensing of protein influences by NO and CO vibrations in heme adducts |
| Q28486387 | DosT and DevS are oxygen-switched kinases in Mycobacterium tuberculosis |
| Q53001265 | Effects of hydrogen sulfide on the heme coordination structure and catalytic activity of the globin-coupled oxygen sensor AfGcHK. |
| Q36197997 | Environmental heme-based sensor proteins: implications for understanding bacterial pathogenesis. |
| Q46913530 | Evidence for displacements of the C-helix by CO ligation and DNA binding to CooA revealed by UV resonance Raman spectroscopy. |
| Q28256992 | Expression of NPAS3 in the human cortex and evidence of its posttranscriptional regulation by miR-17 during development, with implications for schizophrenia |
| Q38975497 | Gas Sensing and Signaling in the PAS-Heme Domain of the Pseudomonas aeruginosa Aer2 Receptor |
| Q53227517 | Gated electron transfer reactions of truncated hemoglobin from Bacillus subtilis differently orientated on SAM-modified electrodes. |
| Q37240534 | Globin-coupled heme containing oxygen sensor soluble adenylate cyclase in Leishmania prevents cell death during hypoxia. |
| Q39902998 | Guanidine hydrochloride-induced unfolding of the three heme coordination states of the CO-sensing transcription factor, CooA. |
| Q38860810 | Heme Oxygenase-1 and Carbon Monoxide in the Heart: The Balancing Act Between Danger Signaling and Pro-Survival |
| Q90132119 | Heme binding to human CLOCK affects interactions with the E-box |
| Q42776350 | Heme binding to the Mammalian circadian clock protein period 2 is nonspecific |
| Q37373615 | Heme displacement mechanism of CooA activation: mutational and Raman spectroscopic evidence |
| Q28278198 | Heme is involved in microRNA processing |
| Q42952015 | Heme ligand binding properties and intradimer interactions in the full-length sensor protein dos from Escherichia coli and its isolated heme domain. |
| Q38094133 | Heme sensor proteins |
| Q34060250 | Heme-Based Sensing by the Mammalian Circadian Protein CLOCK |
| Q37201164 | Heme-based globin-coupled oxygen sensors: linking oxygen binding to functional regulation of diguanylate cyclase, histidine kinase, and methyl-accepting chemotaxis |
| Q34385919 | Hemin Binds to Human Cytoplasmic Arginyl-tRNA Synthetase and Inhibits Its Catalytic Activity |
| Q47261685 | Histidine-Lysine Axial Ligand Switching in a Hemoglobin: A Role for Heme Propionates |
| Q34166721 | How do heme-protein sensors exclude oxygen? Lessons learned from cytochrome c', Nostoc puntiforme heme nitric oxide/oxygen-binding domain, and soluble guanylyl cyclase |
| Q42323687 | Human neuroglobin functions as an oxidative stress-responsive sensor for neuroprotection |
| Q35371781 | Identification and functional and spectral characterization of a globin-coupled histidine kinase from Anaeromyxobacter sp. Fw109-5. |
| Q36358572 | Identification of Cys94 as the distal ligand to the Fe(III) heme in the transcriptional regulator RcoM-2 from Burkholderia xenovorans |
| Q34286846 | Identification of a haem domain in human soluble adenylate cyclase |
| Q39816338 | Identification of subdomains in NADPH oxidase-4 critical for the oxygen-dependent regulation of TASK-1 K+ channels |
| Q34449959 | Iron metabolism regulates p53 signaling through direct heme-p53 interaction and modulation of p53 localization, stability, and function |
| Q33741265 | Iron-based redox switches in biology |
| Q34039950 | Is Nostoc H-NOX a NO sensor or redox switch? |
| Q90145807 | Lessons Learned from 50 Years of Hemoglobin Research: Unstirred and Cell-Free Layers, Electrostatics, Baseball Gloves, and Molten Globules |
| Q37146645 | Ligand dynamics in heme proteins observed by Fourier transform infrared spectroscopy at cryogenic temperatures |
| Q50988737 | Ligand-induced monomerization of Allochromatium vinosum cytochrome c' studied using native mass spectrometry and fluorescence resonance energy transfer. |
| Q50733977 | MEKHLA, a novel domain with similarity to PAS domains, is fused to plant homeodomain-leucine zipper III proteins. |
| Q37624564 | MauG, a diheme enzyme that catalyzes tryptophan tryptophylquinone biosynthesis by remote catalysis |
| Q38649191 | Mechanism and Role of Globin-Coupled Sensor Signalling. |
| Q40725793 | Mechanism of the CO-sensing heme protein CooA: new insights from the truncated heme domain and UVRR spectroscopy |
| Q46534913 | Met(104) is the CO-replaceable ligand at Fe(II) heme in the CO-sensing transcription factor BxRcoM-1. |
| Q83841440 | Modeling proline ligation in the heme-dependent CO sensor, CooA, using small-molecule analogs |
| Q54426795 | Modulation of NO binding to cytochrome c' by distal and proximal haem pocket residues. |
| Q42234182 | Modulation of ligand-heme reactivity by binding pocket residues demonstrated in cytochrome c' over the femtosecond-second temporal range. |
| Q36904037 | Mutations in Tyr808 reveal a potential auto-inhibitory mechanism of guanylate cyclase-B regulation |
| Q28486511 | Mycobacterium tuberculosis DosS is a redox sensor and DosT is a hypoxia sensor |
| Q40642475 | Mycobacterium tuberculosis senses host-derived carbon monoxide during macrophage infection. |
| Q50469819 | NTP-binding properties of the blue-light receptor YtvA and effects of the E105L mutation |
| Q40000351 | New light on NO bonding in Fe(III) heme proteins from resonance Raman spectroscopy and DFT modeling |
| Q34075870 | Nitric oxide and heat shock protein 90 activate soluble guanylate cyclase by driving rapid change in its subunit interactions and heme content. |
| Q37451442 | Nitric oxide signaling in Pseudomonas aeruginosa biofilms mediates phosphodiesterase activity, decreased cyclic di-GMP levels, and enhanced dispersal |
| Q38151386 | Nitric oxide-sensing H-NOX proteins govern bacterial communal behavior |
| Q37997365 | Nitrous oxide production and consumption: regulation of gene expression by gas-sensitive transcription factors |
| Q33821246 | Nuclear resonance vibrational spectroscopy applied to [Fe(OEP)(NO)]: the vibrational assignments of five-coordinate ferrous heme-nitrosyls and implications for electronic structure |
| Q64120783 | Nucleotide Second Messenger-Based Signaling in Extreme Acidophiles of the Species Complex: Partition Between the Core and Variable Gene Complements |
| Q27651661 | O2- and NO-Sensing Mechanism through the DevSR Two-Component System in Mycobacterium smegmatis |
| Q34048405 | Oriented single-crystal nuclear resonance vibrational spectroscopy of [Fe(TPP)(MI)(NO)]: quantitative assessment of the trans effect of NO. |
| Q52910338 | Oxygen detection in biological systems. |
| Q33897916 | Oxygen sensing strategies in mammals and bacteria. |
| Q37146630 | Oxygen-sensing histidine-protein kinases: assays of ligand binding and turnover of response-regulator substrates. |
| Q27649070 | PAS-mediated Dimerization of Soluble Guanylyl Cyclase Revealed by Signal Transduction Histidine Kinase Domain Crystal Structure |
| Q34807825 | PAS/poly-HAMP signalling in Aer-2, a soluble haem-based sensor |
| Q54981072 | Phosphatase activity tunes two-component system sensor detection threshold. |
| Q51831435 | Plant oxygen sensing is mediated by the N-end rule pathway: a milestone in plant anaerobiosis. |
| Q44566730 | Pressure effects reveal that changes in the redox states of the heme iron complexes in the sensor domains of two heme-based oxygen sensor proteins, EcDOS and YddV, have profound effects on their flexibility. |
| Q27658400 | Principles of Ligand Binding within a Completely Buried Cavity in HIF2α PAS-B |
| Q39103477 | Prokaryotic Heme Biosynthesis: Multiple Pathways to a Common Essential Product. |
| Q36834148 | Properties of an unusual heme cofactor in PLP-dependent cystathionine beta-synthase |
| Q50055576 | Protein Dynamics of the Sensor Protein HemAT as Probed by Time-Resolved Step-Scan FTIR Spectroscopy. |
| Q46830658 | Protein conformation changes of HemAT-Bs upon ligand binding probed by ultraviolet resonance Raman spectroscopy |
| Q30421855 | Protein folding modulates the swapped dimerization mechanism of methyl-accepting chemotaxis heme sensors |
| Q46890968 | Pulling NO out of thin air. |
| Q30494280 | Quantitative vibrational dynamics of iron in carbonyl porphyrins |
| Q29617340 | ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis |
| Q36594599 | RcoM: a new single-component transcriptional regulator of CO metabolism in bacteria |
| Q35905342 | Redox-dependent Ligand Switching in a Sensory Heme-binding GAF Domain of the Cyanobacterium Nostoc sp. PCC7120. |
| Q37258637 | Regulation of intracellular heme trafficking revealed by subcellular reporters |
| Q34632437 | Regulation of the phototrophic iron oxidation (pio) genes in Rhodopseudomonas palustris TIE-1 is mediated by the global regulator, FixK. |
| Q36741503 | Regulators of bacterial responses to nitric oxide |
| Q42549246 | Resonance Raman spectra of an O2-binding H-NOX domain reveal heme relaxation upon mutation |
| Q36869377 | Reversible NO motion in crystalline [Fe(Porph)(1-MeIm)(NO)] derivatives |
| Q42111298 | Role of the Per/Arnt/Sim domains in ligand-dependent transformation of the aryl hydrocarbon receptor |
| Q46616506 | Roles of Arg-97 and Phe-113 in regulation of distal ligand binding to heme in the sensor domain of Ec DOS protein. Resonance Raman and mutation study |
| Q42187519 | Site-specific protein dynamics in communication pathway from sensor to signaling domain of oxygen sensor protein, HemAT-Bs: Time-resolved Ultraviolet Resonance Raman Study |
| Q24672531 | Stimulus perception in bacterial signal-transducing histidine kinases |
| Q27654057 | Structural Insight into the Heme-based Redox Sensing by DosS from Mycobacterium tuberculosis |
| Q36671880 | Structural and thermodynamic consequences of b heme binding for monomeric apoglobins and other apoproteins |
| Q27679268 | Structural basis for oxygen sensing and signal transduction of the heme-based sensor protein Aer2 from Pseudomonas aeruginosa |
| Q27683978 | Structure of REV-ERB Ligand-binding Domain Bound to a Porphyrin Antagonist |
| Q27661554 | Structure of cinaciguat (BAY 58-2667) bound to Nostoc H-NOX domain reveals insights into heme-mimetic activation of the soluble guanylyl cyclase |
| Q88543684 | THE AER2 RECEPTOR FROM VIBRIO CHOLERAE IS A DUAL PAS-HEME OXYGEN SENSOR |
| Q47699171 | Target DNA stabilizes Mycobacterium tuberculosis DevR/DosR phosphorylation by the full-length oxygen sensors DevS/DosS and DosT. |
| Q24299093 | The DGCR8 RNA-binding heme domain recognizes primary microRNAs by clamping the hairpin |
| Q34680715 | The Heme-Based Oxygen-Sensor Phosphodiesterase Ec DOS (DosP): Structure-Function Relationships |
| Q34189152 | The N-end rule pathway and regulation by proteolysis |
| Q36423606 | The N-end rule pathway is a sensor of heme |
| Q28265950 | The NPAS3 gene--emerging evidence for a role in psychiatric illness |
| Q39348748 | The NtrY/X two-component system of Brucella spp. acts as a redox sensor and regulates the expression of nitrogen respiration enzymes. |
| Q34150661 | The PpaA/AerR regulators of photosynthesis gene expression from anoxygenic phototrophic proteobacteria contain heme-binding SCHIC domains |
| Q36836299 | The heme-p53 interaction: Linking iron metabolism to p53 signaling and tumorigenesis. |
| Q33325118 | The pH dependence of heme pocket hydration and ligand rebinding kinetics in photodissociated carbonmonoxymyoglobin |
| Q37933077 | The regulatory role of heme in neurons. |
| Q35759782 | The symbiosis regulator CbrA modulates a complex regulatory network affecting the flagellar apparatus and cell envelope proteins |
| Q39902590 | The transcription regulator RcoM-2 from Burkholderia xenovorans is a cysteine-ligated hemoprotein that undergoes a redox-mediated ligand switch |
| Q34049806 | Transcriptional response of Candida albicans to nitric oxide and the role of the YHB1 gene in nitrosative stress and virulence |
| Q46145397 | Ultrafast CO Kinetics in Heme Proteins: Adiabatic Ligand Binding and Heavy Atom Tunneling. |
| Q34304677 | Unexpected NO-dependent DNA binding by the CooA homolog from Carboxydothermus hydrogenoformans |
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