Antioxidants inhibit neuronal toxicity in Parkinson's disease-linked LRRK2

scientific article

Antioxidants inhibit neuronal toxicity in Parkinson's disease-linked LRRK2 is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/ACN3.282
P932PMC publication ID4818746
P698PubMed publication ID27081659

P50authorEng-King TanQ67189690
P2093author name stringPatrick Ho
Brian W Dymock
Dario C Angeles
Kah-Leong Lim
Zhi-Dong Zhou
P2860cites workGTPase activity and neuronal toxicity of Parkinson's disease-associated LRRK2 is regulated by ArfGAP1Q21144926
LRRK2 controls synaptic vesicle storage and mobilization within the recycling poolQ24292798
MAP1B rescues LRRK2 mutant-mediated cytotoxicityQ24295033
The role of oxidative stress in Parkinson's diseaseQ24307946
The familial Parkinsonism gene LRRK2 regulates neurite process morphologyQ24317613
Thiol peroxidases ameliorate LRRK2 mutant-induced mitochondrial and dopaminergic neuronal degeneration in DrosophilaQ24322678
Mutations in LRRK2 increase phosphorylation of peroxiredoxin 3 exacerbating oxidative stress-induced neuronal deathQ24323228
LRRK2 phosphorylates moesin at threonine-558: characterization of how Parkinson's disease mutants affect kinase activityQ29615144
Parkinson's diseaseQ29616302
Piceatannol (3,4,3',5'-tetrahydroxy-trans-stilbene) is a naturally occurring protein-tyrosine kinase inhibitorQ34473126
Small molecule kinase inhibitors for LRRK2 and their application to Parkinson's disease models.Q36015579
Pathogenic mutations in Parkinson diseaseQ36770206
Bioavailability and activity of phytosome complexes from botanical polyphenols: the silymarin, curcumin, green tea, and grape seed extractsQ37608238
Neuropathological assessment of Parkinson's disease: refining the diagnostic criteriaQ37631959
Polyphenols: multipotent therapeutic agents in neurodegenerative diseasesQ38120532
Targeting leucine-rich repeat kinase 2 in Parkinson's diseaseQ38160939
Emerging therapies for Parkinson's disease: from bench to bedside.Q38214044
Neuroprotective effects of umbelliferone and esculetin in a mouse model of Parkinson's diseaseQ39237644
Thymoquinone protects dopaminergic neurons against MPP+ and rotenoneQ46194199
Targeting mitochondria for neuroprotection in Parkinson disease.Q50675296
P4510describes a project that usesImageQuantQ112270642
P433issue4
P921main subjectParkinson's diseaseQ11085
P304page(s)288-294
P577publication date2016-03-02
P1433published inAnnals of clinical and translational neurologyQ27725312
P1476titleAntioxidants inhibit neuronal toxicity in Parkinson's disease-linked LRRK2
P478volume3

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cites work (P2860)
Q64070827Nutrigenomics as a tool to study the impact of diet on aging and age-related diseases: the approach
Q52847929Parkinson disease: Insect screens for PD therapies - keep the flies in.
Q45814729Polymer brain-nanotherapeutics for multipronged inhibition of microglial α-synuclein aggregation, activation, and neurotoxicity.
Q94502456Resveratrol Derivatives as Potential Treatments for Alzheimer's and Parkinson's Disease
Q39263032Targeting LRRK2 in Parkinson's disease: an update on recent developments
Q60960522The Potential Use of Plant Natural Products and Plant Extracts with Antioxidant Properties for the Prevention/Treatment of Neurodegenerative Diseases: In Vitro, In Vivo and Clinical Trials
Q47126437Therapeutic Versatility of Resveratrol Derivatives
Q91866682Using Drosophila as a platform for drug discovery from natural products in Parkinson's disease

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