Translating basic science research to clinical application: models and strategies for intracerebral hemorrhage.

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Translating basic science research to clinical application: models and strategies for intracerebral hemorrhage. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3389/FNEUR.2012.00085
P932PMC publication ID3361857
P698PubMed publication ID22661966
P5875ResearchGate publication ID225096028

P50authorSylvain DoréQ57047750
P2093author name stringSean Robbins
Christopher C Leonardo
P2860cites workDescribing functioning, disability, and health with the International Classification of Functioning, Disability, and Health Brief Core Set for Stroke.Q50976891
Elevated serum S100B levels indicate a higher risk of hemorrhagic transformation after thrombolytic therapy in acute stroke.Q51743594
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Serum glial fibrillary acidic protein as a biomarker for intracerebral haemorrhage in patients with acute strokeQ36142617
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Rodent models of intracerebral hemorrhage.Q37793695
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Natural course of perihemorrhagic edema after intracerebral hemorrhage.Q37898918
Is the spontaneously hypertensive stroke prone rat a pertinent model of sub cortical ischemic stroke? A systematic reviewQ37939375
Challenges and controversies in the medical management of primary and antithrombotic-related intracerebral hemorrhageQ37978627
Do current animal models of intracerebral hemorrhage mirror the human pathology?Q38170028
Hemorrhage burden predicts recurrent intracerebral hemorrhage after lobar hemorrhageQ40518629
Matrix metalloproteinase-9 pretreatment level predicts intracranial hemorrhagic complications after thrombolysis in human stroke.Q40607050
Brain edema after experimental intracerebral hemorrhage: role of hemoglobin degradation productsQ42170839
Erythrocytes and delayed brain edema formation following intracerebral hemorrhage in ratsQ42464660
Collagenase-induced intracerebral hemorrhage in ratsQ42479802
Absence of early proinflammatory cytokine expression in experimental intracerebral hemorrhageQ42508600
Experimental intracerebral hemorrhage in rats. Magnetic resonance imaging and histopathological correlatesQ42551811
Asymptomatic hemorrhagic transformation of infarction and its relationship with functional outcome and stroke subtype: assessment from the Tinzaparin in Acute Ischaemic Stroke TrialQ42844275
Long-term histological and behavioural characterisation of a collagenase-induced model of intracerebral haemorrhage in ratsQ42988685
Effects of perindopril-based lowering of blood pressure on intracerebral hemorrhage related to amyloid angiopathy: the PROGRESS trialQ43203769
Age-dependent lethality in novel transgenic mouse models of central nervous system arteriovenous malformationsQ44235352
Safety and outcomes following thrombolytic treatment in stroke patients who had received prior treatment with anticoagulantsQ44442729
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Warfarin, hematoma expansion, and outcome of intracerebral hemorrhageQ45081496
Spontaneous stroke in a genetic model of hypertension in miceQ46508463
Cerebral amyloid angiopathy: incidence and complications in the aging brain. II. The distribution of amyloid vascular changesQ46640803
Long-term effects of experimental intracerebral hemorrhage: the role of ironQ46969940
Plasma cellular-fibronectin concentration predicts hemorrhagic transformation after thrombolytic therapy in acute ischemic stroke.Q47421490
Subarachnoid hemorrhage model in the rat: modification of the endovascular filament modelQ47628992
Inflammatory responses in the rat brain in response to different methods of intra-cerebral administrationQ47979823
Apolipoprotein E markedly facilitates age-dependent cerebral amyloid angiopathy and spontaneous hemorrhage in amyloid precursor protein transgenic mice.Q48215367
Clinical significance of alphaII-spectrin breakdown products in cerebrospinal fluid after severe traumatic brain injuryQ48233639
Cerebral amyloid angiopathy in the elderly: vessel walls changes and relationship with dementiaQ48235883
Neuropsychological impairment after hemorrhagic stroke in basal gangliaQ48254360
Early hemodynamic changes in experimental intracerebral hemorrhageQ48280640
Assessing cognitive function after intracerebral hemorrhage in rats.Q48312156
Behavioral tests after intracerebral hemorrhage in the rat.Q48475050
CT and diffusion-weighted MR imaging in randomized order: diffusion-weighted imaging results in higher accuracy and lower interrater variability in the diagnosis of hyperacute ischemic strokeQ48491602
Comparison of experimental rat models of early brain injury after subarachnoid hemorrhageQ48510631
Determination of serum visinin like protein-1 and its potential for the diagnosis of brain injury due to the stroke: a pilot study.Q48686212
Stroke: Brain natriuretic peptide could be a biomarker for outcomes after cardioembolic strokeQ48695759
Plasma β-amyloid levels in cerebral amyloid angiopathy-associated hemorrhagic stroke.Q48702297
Pentraxin 3: a novel and independent prognostic marker in ischemic stroke.Q48770462
Characterisation of the diagnostic window of serum glial fibrillary acidic protein for the differentiation of intracerebral haemorrhage and ischaemic strokeQ48822422
Therapeutic benefit of urocortin in rats with intracerebral hemorrhageQ48857061
Glial responses, neuron death and lesion resolution after intracerebral hemorrhage in young vs. aged rats.Q48857393
Spontaneous hemorrhagic stroke in a mouse model of cerebral amyloid angiopathy.Q48974670
Lobar intracerebral hemorrhage model in pigs: rapid edema development in perihematomal white matterQ49105220
Amyloid-β contributes to blood-brain barrier leakage in transgenic human amyloid precursor protein mice and in humans with cerebral amyloid angiopathyQ49409019
Preclinical and clinical research on inflammation after intracerebral hemorrhageQ24594191
Cerebral microinfarcts: the invisible lesionsQ27026027
Guidelines for the Early Management of Adults With Ischemic StrokeQ28297859
Structural and functional disruption of vascular smooth muscle cells in a transgenic mouse model of amyloid angiopathyQ28359737
Intracerebral hemorrhage induces macrophage activation and matrix metalloproteinasesQ28580357
Heart disease and stroke statistics--2012 update: a report from the American Heart AssociationQ29547909
Update of the stroke therapy academic industry roundtable preclinical recommendationsQ29615508
1,026 experimental treatments in acute strokeQ29615509
Analysis of cerebral amyloid angiopathy in a transgenic mouse model of Alzheimer disease using in vivo multiphoton microscopyQ30658000
Intracerebral haemorrhageQ33442365
Initial CT findings in 753 patients with severe head injury. A report from the NIH Traumatic Coma Data BankQ33454197
Neuroprotective role of haptoglobin after intracerebral hemorrhageQ33699650
Recommendations for standards regarding preclinical neuroprotective and restorative drug developmentQ33785562
A rat model of studying tissue-type plasminogen activator thrombolysis in ischemic stroke with diabetesQ34066733
Cerebral amyloid angiopathy in the elderlyQ34108298
Traumatic subarachnoid hemorrhage: demographic and clinical study of 750 patients from the European brain injury consortium survey of head injuries.Q34114024
αII-spectrin breakdown products (SBDPs): diagnosis and outcome in severe traumatic brain injury patientsQ34142573
Aging and cerebrovascular dysfunction: contribution of hypertension, cerebral amyloid angiopathy, and immunotherapyQ34219814
Recommendations for clinical trial evaluation of acute stroke therapies.Q34300670
Abeta is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis.Q34341174
Tuftsin fragment 1-3 is beneficial when delivered after the induction of intracerebral hemorrhage.Q34391036
Hyperglycemia-induced cerebral hematoma expansion is mediated by plasma kallikreinQ34572652
Blood-based diagnostics of traumatic brain injuriesQ34714369
The development of an improved preclinical mouse model of intracerebral hemorrhage using double infusion of autologous whole bloodQ34789898
Brain injury after intracerebral hemorrhage in spontaneously hypertensive rats.Q35022280
White matter damage and the effect of matrix metalloproteinases in type 2 diabetic mice after strokeQ35025916
Biokinetic analysis of ubiquitin C-terminal hydrolase-L1 (UCH-L1) in severe traumatic brain injury patient biofluidsQ35040539
Molecular pathophysiology of cerebral hemorrhage: secondary brain injuryQ35070264
Caspase-mediated cleavage of glial fibrillary acidic protein within degenerating astrocytes of the Alzheimer's disease brainQ35088000
Blocking the apolipoprotein E/amyloid-β interaction reduces fibrillar vascular amyloid deposition and cerebral microhemorrhages in TgSwDI miceQ35095392
Experimental intracerebral hemorrhage: avoiding pitfalls in translational researchQ35534164
P304page(s)85
P577publication date2012-05-29
P1433published inFrontiers in NeurologyQ15817039
P1476titleTranslating basic science research to clinical application: models and strategies for intracerebral hemorrhage
P478volume3

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cites work (P2860)
Q55019304A Comparison of Pathophysiology in Humans and Rodent Models of Subarachnoid Hemorrhage.
Q35389143Experimental subarachnoid hemorrhage in rats: comparison of two endovascular perforation techniques with respect to success rate, confounding pathologies and early hippocampal tissue lesion pattern
Q37420266Fast neuroprotection (fast-NPRX) for acute ischemic stroke victims: the time for treatment is now.
Q26865843Intracerebral hemorrhage in mouse models: therapeutic interventions and functional recovery
Q35123058The relationship between the serum levels of ferritin and the radiological brain injury indices in patients with spontaneous intracerebral hemorrhage
Q52597283Uncovering the Rosetta Stone: Report from the First Annual Conference on Key Elements in Translating Stroke Therapeutics from Pre-Clinical to Clinical.

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