| P2093 | author name string | Thomas W Kensler | |
| | James L Boyer | |
| | Albert Mennone | |
| | Lee R Hagey | |
| | Jittima Weerachayaphorn | |
| | Carol J Soroka | |
| | Kathy Harry | |
| P2860 | cites work | Genetic or pharmacologic amplification of nrf2 signaling inhibits acute inflammatory liver injury in mice | Q36732083 |
| | ANIT-induced intrahepatic cholestasis alters hepatobiliary transporter expression via Nrf2-dependent and independent signaling | Q37148632 |
| | Nrf2 activation enhances biliary excretion of sulfobromophthalein by inducing glutathione-S-transferase activity | Q37175447 |
| | Nrf2 the rescue: effects of the antioxidative/electrophilic response on the liver | Q37685403 |
| | Nuclear receptor regulation of the adaptive response of bile acid transporters in cholestasis. | Q37737634 |
| | Up-regulation of the human gamma-glutamylcysteine synthetase regulatory subunit gene involves binding of Nrf-2 to an electrophile responsive element | Q38321807 |
| | Induction of avian musculoaponeurotic fibrosarcoma proteins by toxic bile acid inhibits expression of glutathione synthetic enzymes and contributes to cholestatic liver injury in mice | Q39741359 |
| | Activation of nuclear factor (erythroid-2 like) factor 2 by toxic bile acids provokes adaptive defense responses to enhance cell survival at the emergence of oxidative stress | Q40088792 |
| | Dysregulation of glutathione synthesis during cholestasis in mice: molecular mechanisms and therapeutic implications | Q42099362 |
| | Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice | Q43238371 |
| | Loss of Nrf2 markedly exacerbates nonalcoholic steatohepatitis. | Q43242090 |
| | Cellular localization and up-regulation of multidrug resistance-associated protein 3 in hepatocytes and cholangiocytes during obstructive cholestasis in rat liver | Q43563069 |
| | Oxidant stress is a significant feature of primary biliary cirrhosis. | Q44360006 |
| | Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice | Q44569549 |
| | Nuclear factor-eythroid 2-related factor 2 prevents alcohol-induced fulminant liver injury | Q46090988 |
| | CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice | Q46573657 |
| | Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity. | Q46808839 |
| | Determinants of glutathione efflux and biliary GSH/GSSG ratio in perfused rat liver | Q69368071 |
| | Mrp4-/- mice have an impaired cytoprotective response in obstructive cholestasis | Q83182823 |
| | Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors | Q24290397 |
| | OSTalpha-OSTbeta: a major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia | Q24297458 |
| | Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region | Q24563505 |
| | Nuclear factor erythroid 2-related factor 2 is a positive regulator of human bile salt export pump expression | Q24617391 |
| | The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity | Q24630723 |
| | Bile acids: regulation of synthesis | Q24658139 |
| | A new mathematical model for relative quantification in real-time RT-PCR | Q27860781 |
| | Oxidative and electrophilic stress induces multidrug resistance-associated protein transporters via the nuclear factor-E2-related factor-2 transcriptional pathway | Q28238852 |
| | Differential regulation of bile acid homeostasis by the farnesoid X receptor in liver and intestine | Q28242281 |
| | An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements | Q28244853 |
| | An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen | Q28361995 |
| | Parallel induction of heme oxygenase-1 and chemoprotective phase 2 enzymes by electrophiles and antioxidants: regulation by upstream antioxidant-responsive elements (ARE) | Q28378816 |
| | Radixin is required to maintain apical canalicular membrane structure and function in rat hepatocytes | Q28564528 |
| | NHERF-1 binds to Mrp2 and regulates hepatic Mrp2 expression and function | Q28569226 |
| | Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway | Q29547371 |
| | Glutathione transferases | Q29616501 |
| | Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis | Q29619610 |
| | High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes | Q31783158 |
| | Mouse organic solute transporter alpha deficiency enhances renal excretion of bile acids and attenuates cholestasis | Q33644429 |
| | Diurnal variations of mouse plasma and hepatic bile acid concentrations as well as expression of biosynthetic enzymes and transporters | Q33827979 |
| | Suppression of sterol 12alpha-hydroxylase transcription by the short heterodimer partner: insights into the repression mechanism | Q33948442 |
| | Transcriptional regulation of the human sterol 12alpha-hydroxylase gene (CYP8B1): roles of heaptocyte nuclear factor 4alpha in mediating bile acid repression | Q34089245 |
| | Effects of feeding bile acids and a bile acid sequestrant on hepatic bile acid composition in mice | Q34188025 |
| | Participation of nuclear factor (erythroid 2-related), factor 2 in ameliorating lithocholic acid-induced cholestatic liver injury in mice | Q34389042 |
| | Transcription factor Nrf2 regulates SHP and lipogenic gene expression in hepatic lipid metabolism | Q34425926 |
| | An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids. | Q34732527 |
| | Nuclear factor-E2-related factor 2 expression in liver is critical for induction of NAD(P)H:quinone oxidoreductase 1 during cholestasis. | Q35565444 |
| | Molecular mechanisms activating the Nrf2-Keap1 pathway of antioxidant gene regulation | Q36038160 |
| | Induction of Mrp3 and Mrp4 transporters during acetaminophen hepatotoxicity is dependent on Nrf2 | Q36407344 |
| P433 | issue | 9 | |
| P304 | page(s) | G925-36 | |
| P577 | publication date | 2012-02-16 | |
| P1433 | published in | American Journal of Physiology - Gastrointestinal and Liver Physiology | Q15765756 |
| P1476 | title | Nuclear factor-E2-related factor 2 is a major determinant of bile acid homeostasis in the liver and intestine | |
| P478 | volume | 302 | |