Mastocytosis: pathology, genetics, and current options for therapy

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Mastocytosis: pathology, genetics, and current options for therapy is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1080/10428190400010775
P698PubMed publication ID15621779

P50authorDean D. MetcalfeQ90856971
P2093author name stringHans-Peter Horny
Karl Sotlar
Luis Escribano
Peter Valent
Wolfgang R Sperr
Michel Arock
Matthias Mayerhofer
Cem Akin
Manuela Födinger
Robert Fritsche-Polanz
P2860cites workActivating and dominant inactivating c-KIT catalytic domain mutations in distinct clinical forms of human mastocytosisQ22001442
The alpha form of human tryptase is the predominant type present in blood at baseline in normal subjects and is elevated in those with systemic mastocytosisQ24676988
One-step detection of c-kit point mutations using peptide nucleic acid-mediated polymerase chain reaction clamping and hybridization probesQ24685763
CHIC2 deletion, a surrogate for FIP1L1-PDGFRA fusion, occurs in systemic mastocytosis associated with eosinophilia and predicts response to imatinib mesylate therapyQ28184867
Treatment of cutaneous mastocytosisQ28192647
Temporary response of localized intracranial mast cell sarcoma to combination chemotherapyQ32054092
A case of 'smouldering' mastocytosis with high mast cell burden, monoclonal myeloid cells, and C-KIT mutation Asp-816-ValQ33146408
Mastocytosis: mediator-related signs and symptomsQ33147535
Hematologic manifestations of systemic mast cell disease: A prospective study of laboratory and morphologic features and their relation to prognosisQ33375266
Blood findings in generalized mastocytosis: evidence of frequent simultaneous occurrence of myeloproliferative disordersQ33393956
Increased bone marrow mast cells in preleukemic syndromes, acute leukemia, and lymphoproliferative disordersQ33487332
Recent advances in mastocytosis research. Summary of the Vienna Mastocytosis Meeting 1998.Q33755884
Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorderQ33784323
Myelomastocytic overlap syndromes: biology, criteria, and relationship to mastocytosisQ33948611
Diagnostic criteria and classification of mastocytosis: a consensus proposalQ33948617
Treatment of systemic mast cell disordersQ33979061
Clinical and biologic diversity of leukemias occurring in patients with mastocytosis.Q34066643
Mutation analysis of C-KIT in patients with myelodysplastic syndromes without mastocytosis and cases of systemic mastocytosis.Q43622703
Immunohistochemical properties of bone marrow mast cells in systemic mastocytosis: evidence for expression of CD2, CD117/Kit, and bcl-x(L).Q43623319
Bone marrow findings in systemic mastocytosisQ43628628
Expression of mast cell tryptase by myeloblasts in a group of patients with acute myeloid leukemia.Q43745319
Stem cell factor-induced bone marrow mast cell hyperplasia mimicking systemic mastocytosis (SM): histopathologic and morphologic evaluation with special reference to recently established SM-criteriaQ43987776
A novel form of mastocytosis associated with a transmembrane c-kit mutation and response to imatinibQ44534510
Effects of tyrosine kinase inhibitor STI571 on human mast cells bearing wild-type or mutated c-kitQ44539087
Imatinib for systemic mast-cell diseaseQ44558628
Treatment of systemic mast cell disease with 2-chlorodeoxyadenosineQ44678922
Slowly progressive systemic mastocytosis with high mast-cell burden and no evidence of a non-mast-cell hematologic disorder: an example of a smoldering case?Q44802499
Tryptase levels as an indicator of mast-cell activation in systemic anaphylaxis and mastocytosis.Q52461216
Constitutively active mutant D816VKit induces megakayocyte and mast cell differentiation of early haemopoietic cells from murine foetal liver.Q53381584
CD25 indicates the neoplastic phenotype of mast cells: a novel immunohistochemical marker for the diagnosis of systemic mastocytosis (SM) in routinely processed bone marrow biopsy specimens.Q54701336
Systemic mastocytosis associated with acute myeloid leukaemia: report of two cases and detection of the c-kit mutation Asp-816 to ValQ57826804
Spleen colony-forming cell as common precursor for tissue mast cells and granulocytesQ59060090
Serum tryptase levels in patients with mastocytosis: correlation with mast cell burden and implication for defining the category of disease.Q34133511
Mast cell leukemia: report of a case and review of the literatureQ34165793
Mast cell leukaemia: evidence for bone marrow origin of the pathological cloneQ34165830
Variable expression of activation-linked surface antigens on human mast cells in health and diseaseQ34211542
Clinical and histopathological aspects of cutaneous mastocytosisQ34264289
Diagnosis of mastocytosis: value of cytochemistry and immunohistochemistryQ34264295
Diagnosis of mastocytosis: general histopathological aspects, morphological criteria, and immunohistochemical findings.Q34264299
Clinical utility of tryptase levels in systemic mastocytosis and associated hematologic disordersQ34264305
Utility of flow cytometric analysis of mast cells in the diagnosis and classification of adult mastocytosisQ34264308
Mast cells and mast cell neoplasia: a reviewQ34304654
Kit and c-kit mutations in mastocytosis: a short overview with special reference to novel molecular and diagnostic concepts.Q34580164
Smouldering mastocytosis: a novel subtype of systemic mastocytosis with slow progressionQ34580198
Cutaneous mastocytosis -- clinical heterogeneity.Q34580209
Myelomastocytic leukemia: myeloid neoplasm characterized by partial differentiation of mast cell-lineage cellsQ34658607
Mastocytosis: current concepts in diagnosis and treatmentQ35026318
Tryptase a novel biochemical marker of acute myeloid leukemiaQ35076231
Aggressive systemic mastocytosis and related mast cell disorders: current treatment options and proposed response criteriaQ35101794
Diagnosis and treatment of systemic mastocytosis: state of the art.Q35203889
Clinical, genetic, and therapeutic insights into systemic mast cell diseaseQ35608106
Response to therapy with interferon alpha-2b and prednisolone in aggressive systemic mastocytosis: report of five cases and review of the literature.Q35612339
Imatinib therapy in clonal eosinophilic disorders, including systemic mastocytosisQ35828746
Diagnosis and classification of mast cell proliferative disorders: delineation from immunologic diseases and non-mast cell hematopoietic neoplasms.Q35829710
Development of human mast cells from umbilical cord blood cells by recombinant human and murine c-kit ligandQ36070756
Spleen findings in generalized mastocytosis. A clinicopathologic studyQ36263416
Classification and diagnosis of mastocytosis: current statusQ36518951
The liver, spleen, and lymph nodes in mastocytosisQ36518988
The growth and differentiation of mast cellsQ36928390
Mast cell sarcoma of the larynxQ37208432
Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit productQ38315689
Liver findings in generalized mastocytosis. A clinicopathologic studyQ38598696
Significance of systemic mast cell disease with associated hematologic disordersQ39715028
The riddle of the mast cell: kit(CD117)-ligand as the missing link?Q40388512
Detection of novel CD antigens on the surface of human mast cells and basophilsQ40731114
The c-KIT mutation causing human mastocytosis is resistant to STI571 and other KIT kinase inhibitors; kinases with enzymatic site mutations show different inhibitor sensitivity profiles than wild-type kinases and those with regulatory-type mutationsQ40748765
Expression, epitope analysis, and functional role of the LFA-2 antigen detectable on neoplastic mast cells.Q40764561
Identification of activating c-kit mutations in adult-, but not in childhood-onset indolent mastocytosis: a possible explanation for divergent clinical behaviorQ40987642
Detection of c-kit mutation Asp 816 to Val in microdissected bone marrow infiltrates in a case of systemic mastocytosis associated with chronic myelomonocytic leukaemia.Q42937195
Mast cell disease associated with acute myeloid leukemia: detection of a new c-kit mutation Asp816HisQ43441750
Treatment of systemic mast-cell disease with cladribineQ43527780
P433issue1
P304page(s)35-48
P577publication date2005-01-01
P1433published inLeukemia & LymphomaQ6534493
P1476titleMastocytosis: pathology, genetics, and current options for therapy
P478volume46

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cites work (P2860)
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Q36527862Urticaria pigmentosa and mastocytosis: the role of immunophenotyping in diagnosis and determining response to treatment.
Q83130673Utility of the World Heath Organization classification criteria for the diagnosis of systemic mastocytosis in bone marrow

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