Ty1 retrovirus-like element Gag contains overlapping restriction factor and nucleic acid chaperone functions.

scientific article

Ty1 retrovirus-like element Gag contains overlapping restriction factor and nucleic acid chaperone functions. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/NAR/GKV695
P932PMC publication ID4551931
P698PubMed publication ID26160887
P5875ResearchGate publication ID279952445

P50authorLeszek BłaszczykQ85567379
Julita GumnaQ85567382
Katarzyna Pachulska-WieczorekQ59551132
P2093author name stringKatarzyna J Purzycka
David J Garfinkel
Agniva Saha
Yuri Nishida
P2860cites workMechanistic studies of mini-TAR RNA/DNA annealing in the absence and presence of HIV-1 nucleocapsid proteinQ80234107
Structural determinants of HIV-1 nucleocapsid protein for cTAR DNA binding and destabilization, and correlation with inhibition of self-primed DNA synthesisQ81690042
Cap-assisted internal initiation of translation of histone H4Q83264155
Retroviral RNA Dimerization and Packaging: The What, How, When, Where, and WhyQ21131436
RNA chaperoning and intrinsic disorder in the core proteins of FlaviviridaeQ27485379
The HIV-1 transcriptional activator Tat has potent nucleic acid chaperoning activities in vitroQ27486255
Ty3 capsid mutations reveal early and late functions of the amino-terminal domainQ27931343
Guide to yeast genetics and molecular biologyQ29615111
Vectors for the inducible overexpression of glutathione S-transferase fusion proteins in yeastQ29618547
Visualizing the ai5γ group IIB intronQ30571375
The genomic RNA in Ty1 virus-like particles is dimericQ33787384
5' to 3' mRNA decay factors colocalize with Ty1 gag and human APOBEC3G and promote Ty1 retrotranspositionQ33826821
The yeast Ty3 retrotransposon contains a 5'-3' bipartite primer-binding site and encodes nucleocapsid protein NCp9 functionally homologous to HIV-1 NCp7Q33889345
Endogenous retroviruses of sheep: a model system for understanding physiological adaptation to an evolving ruminant genome.Q34263794
Similarities and differences in the nucleic acid chaperone activity of HIV-2 and HIV-1 nucleocapsid proteins in vitroQ34486061
Post-transcriptional Cosuppression of Ty1 RetrotranspositionQ34618471
Temperature effects on the rate of ty transpositionQ34681047
Features, processing states, and heterologous protein interactions in the modulation of the retroviral nucleocapsid protein functionQ34775654
Role of HIV-1 nucleocapsid protein in HIV-1 reverse transcriptionQ34775658
Characterization of a nucleocapsid-like region and of two distinct primer tRNALys,2 binding sites in the endogenous retrovirus GypsyQ35128110
Molecular mechanism of scanning and start codon selection in eukaryotesQ35192105
The Ty1 LTR-retrotransposon of budding yeast, Saccharomyces cerevisiaeQ35441519
A trans-dominant form of Gag restricts Ty1 retrotransposition and mediates copy number control.Q35488212
A critical proteolytic cleavage site near the C terminus of the yeast retrotransposon Ty1 Gag proteinQ35866466
Ty1 reverse transcriptase does not read through the proposed 2',5'-branched retrotransposition intermediate in vitroQ35946133
Nucleic acid chaperone activity of HIV-1 nucleocapsid protein: critical role in reverse transcription and molecular mechanismQ36258296
Chromatin-associated genes protect the yeast genome from Ty1 insertional mutagenesisQ36391795
Secondary structure and the role in translation initiation of the 5'-terminal region of p53 mRNA.Q53231910
Rapid kinetics of protein-nucleic acid interaction is a major component of HIV-1 nucleocapsid protein's nucleic acid chaperone functionQ56893915
XtalPred: a web server for prediction of protein crystallizabilityQ56978525
A novel epitope tag system to study protein targeting and organelle biogenesis in Trypanosoma bruceiQ58858878
Ribosomal frameshifting in the yeast retrotransposon Ty: tRNAs induce slippage on a 7 nucleotide minimal siteQ68468601
Integration of the yeast retrotransposon Ty1 is targeted to regions upstream of genes transcribed by RNA polymerase IIIQ70993643
The GAG-like protein of the yeast Ty1 retrotransposon contains a nucleic acid chaperone domain analogous to retroviral nucleocapsid proteinsQ73680394
Transmission electron microscopy reveals an optimal HIV-1 nucleocapsid aggregation with single-stranded nucleic acids and the mature HIV-1 nucleocapsid proteinQ79187696
Ty3 nucleocapsid controls localization of particle assemblyQ36483898
Efficient Homologous Recombination of Ty1 Element cDNA When Integration Is BlockedQ36666908
Exploring Ty1 retrotransposon RNA structure within virus-like particlesQ36668768
Functional organization of the retrotransposon Ty from Saccharomyces cerevisiae: Ty protease is required for transpositionQ36786045
Posttranslational Control of Ty1 Retrotransposition Occurs at the Level of Protein ProcessingQ36817719
Retrotransposon Ty1 RNA contains a 5'-terminal long-range pseudoknot required for efficient reverse transcriptionQ36915008
Retroviral nucleocapsid proteins display nonequivalent levels of nucleic acid chaperone activityQ36933996
Targeting the viral nucleocapsid protein in anti-HIV-1 therapy.Q37066805
RNA chaperones, RNA annealers and RNA helicasesQ37112437
Single-step selection for Ty1 element retrotranspositionQ37389260
Differential contribution of basic residues to HIV-1 nucleocapsid protein's nucleic acid chaperone function and retroviral replicationQ37606985
RNA from the yeast transposable element Ty1 has both ends in the direct repeats, a structure similar to retrovirus RNAQ37609919
Properties and functions of the nucleocapsid protein in virus assemblyQ37820816
The foamy virus Gag proteins: what makes them different?Q38093352
Capsid-binding retrovirus restriction factors: discovery, restriction specificity and implications for the development of novel therapeuticsQ38136549
HIV-1 nucleocapsid protein as a nucleic acid chaperone: spectroscopic study of its helix-destabilizing properties, structural binding specificity, and annealing activityQ38288379
Multiple molecular determinants for retrotransposition in a primer tRNAQ38300846
DNA strand exchange and selective DNA annealing promoted by the human immunodeficiency virus type 1 nucleocapsid proteinQ38304784
The in vitro loose dimer structure and rearrangements of the HIV-2 leader RNA.Q38319235
The fragile X mental retardation protein has nucleic acid chaperone propertiesQ38342235
A 5'-3' long-range interaction in Ty1 RNA controls its reverse transcription and retrotransposition.Q39647913
A nucleocapsid functionality contained within the amino terminus of the Ty1 protease that is distinct and separable from proteolytic activityQ39681715
Eukaryotic start and stop translation sites.Q40504517
Involvement of cDNA in homologous recombination between Ty elements in Saccharomyces cerevisiaeQ40678504
Expression and purification of soluble recombinant full length HIV-1 Pr55(Gag) protein in Escherichia coli.Q42219797
Distinct binding interactions of HIV-1 Gag to Psi and non-Psi RNAs: implications for viral genomic RNA packaging.Q42288399
Sequence of the yeast protein expression plasmid pEG(KT).Q42611120
Genes of the Pseudoviridae (Ty1/copia retrotransposons).Q42687102
Effect of Mg(2+) and Na(+) on the nucleic acid chaperone activity of HIV-1 nucleocapsid protein: implications for reverse transcriptionQ43109836
Identification and characterization of critical cis-acting sequences within the yeast Ty1 retrotransposonQ43207339
Reverse transcriptase activity and Ty RNA are associated with virus-like particles in yeastQ43603969
Structural determinants within the subunit protein of Ty1 virus-like particlesQ44564296
Ordered aggregation of ribonucleic acids by the human immunodeficiency virus type 1 nucleocapsid protein.Q44821597
Contribution of the esterified amino acid to the binding of aminoacylated tRNAs to the ribosomal P- and A-sitesQ44925133
Properties and growth mechanism of the ordered aggregation of a model RNA by the HIV-1 nucleocapsid protein: an electron microscopy investigationQ44987232
Human immunodeficiency virus nucleocapsid protein accelerates strand transfer of the terminally redundant sequences involved in reverse transcriptionQ45781894
Analysis of TYA protein regions necessary for formation of the Ty1 virus-like particle structure.Q45787168
Ion effects on ligand-nucleic acid interactionsQ46833485
The functions and relationships of Ty-VLP proteins in yeast reflect those of mammalian retroviral proteinsQ48346640
P275copyright licenseCreative Commons Attribution-NonCommercial 4.0 InternationalQ34179348
P6216copyright statuscopyrightedQ50423863
P433issue15
P407language of work or nameEnglishQ1860
P921main subjectmolecular chaperonesQ422496
P304page(s)7414-7431
P577publication date2015-07-08
P1433published inNucleic Acids ResearchQ135122
P1476titleTy1 retrovirus-like element Gag contains overlapping restriction factor and nucleic acid chaperone functions
P478volume43

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cites work (P2860)
Q38721750A normal genetic variation modulates synaptic MMP-9 protein levels and the severity of schizophrenia symptoms
Q36784423A self-encoded capsid derivative restricts Ty1 retrotransposition in Saccharomyces
Q36812404Characterizing the functions of Ty1 Gag and the Gag-derived restriction factor p22/p18
Q40079103Co-option of endogenous viral sequences for host cell function
Q52309955Control of yeast retrotransposons mediated through nucleoporin evolution.
Q26739675Determinants of Genomic RNA Encapsidation in the Saccharomyces cerevisiae Long Terminal Repeat Retrotransposons Ty1 and Ty3
Q89830491Evolution of Ty1 copy number control in yeast by horizontal transfer and recombination
Q26771437Insertion of Retrotransposons at Chromosome Ends: Adaptive Response to Chromosome Maintenance
Q39240327Repetitive DNA loci and their modulation by the non-canonical nucleic acid structures R-loops and G-quadruplexes
Q93008967Retroviral-like determinants and functions required for dimerization of Ty1 retrotransposon RNA
Q46235556Ribosome Biogenesis Modulates Ty1 Copy Number Control in Saccharomyces cerevisiae.
Q38844599Structure of Ty1 Internally Initiated RNA Influences Restriction Factor Expression
Q38818608Structure-Function Model for Kissing Loop Interactions That Initiate Dimerization of Ty1 RNA.
Q52376071The Mediator co-activator complex regulates Ty1 retromobility by controlling the balance between Ty1i and Ty1 promoters.
Q35801440The Ty1 Retrotransposon Restriction Factor p22 Targets Gag.
Q40253679The frenemies within: viruses, retrotransposons and plasmids that naturally infect Saccharomyces yeasts
Q27303006The matrix domain contributes to the nucleic acid chaperone activity of HIV-2 Gag.
Q36812359Ty1 escapes restriction by the self-encoded factor p22 through mutations in capsid

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