Suberoylanilide hydroxamic acid (SAHA; vorinostat) suppresses translation of cyclin D1 in mantle cell lymphoma cells

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Suberoylanilide hydroxamic acid (SAHA; vorinostat) suppresses translation of cyclin D1 in mantle cell lymphoma cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1182/BLOOD-2005-11-026344
P932PMC publication ID1988938
P698PubMed publication ID17606765
P5875ResearchGate publication ID6230514

P2093author name stringH Phillip Koeffler
Norihiko Kawamata
John Chen
P2860cites workHistone deacetylases (HDACs): characterization of the classical HDAC familyQ24535587
High frequency of mutations of the PIK3CA gene in human cancersQ28131776
Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathwayQ28237113
Translational control by MAPK signaling in long-term synaptic plasticity and memoryQ28249953
The p46 subunit of eukaryotic initiation factor (eIF)-4F exchanges with eIF-4AQ28608939
A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)Q28640016
Regulation of translation initiation by FRAP/mTORQ29620398
eIF4E activity is regulated at multiple levelsQ33601634
Survival signalling by Akt and eIF4E in oncogenesis and cancer therapyQ34306865
Molecular basis of mantle cell lymphomaQ35612063
PI3K/Akt signalling pathway and cancer.Q35692250
Proteomic analysis of mantle-cell lymphoma by protein microarrayQ35847477
Pathogenesis of mantle-cell lymphoma: all oncogenic roads lead to dysregulation of cell cycle and DNA damage response pathwaysQ36254627
Current treatment approaches for mantle-cell lymphomaQ36254655
Akt-regulated pathways in prostate cancerQ36313185
Elevated levels of cyclin D1 protein in response to increased expression of eukaryotic initiation factor 4EQ36827075
Cyclin D1 transgene impedes lymphocyte maturation and collaborates in lymphomagenesis with the myc geneQ37631754
Angiopoietin-1 modulates endothelial cell function and gene expression via the transcription factor FKHR (FOXO1).Q38341473
The T-cell receptor regulates Akt (protein kinase B) via a pathway involving Rac1 and phosphatidylinositide 3-kinaseQ39454531
Inhibition of EGFR/PI3K/AKT cell survival pathway promotes TSA's effect on cell death and migration in human ovarian cancer cellsQ40268108
Histone deacetylase inhibitors reduce VEGF production and induce growth suppression and apoptosis in human mantle cell lymphomaQ40341141
Histone deacetylase inhibitors profoundly decrease proliferation of human lymphoid cancer cell lines.Q40468483
Cyclin D1 and c-myc internal ribosome entry site (IRES)-dependent translation is regulated by AKT activity and enhanced by rapamycin through a p38 MAPK- and ERK-dependent pathway.Q40474381
Proteasome inhibitor PS-341 causes cell growth arrest and apoptosis in human glioblastoma multiforme (GBM).Q40494554
Stabilization of p53 is a novel mechanism for proapoptotic function of NF-kappaB.Q40563919
AKT activity determines sensitivity to mammalian target of rapamycin (mTOR) inhibitors by regulating cyclin D1 and c-myc expressionQ40623520
Cyclin D1/bcl-1 cooperates with myc genes in the generation of B-cell lymphoma in transgenic mice.Q40792693
The catalytic subunit of phosphoinositide 3-kinase: requirements for oncogenicityQ41721937
Soluble CD40 ligand induces selective proliferation of lymphoma cells in primary mantle cell lymphoma cell cultures.Q42493107
Phosphorylation of cyclin D1 at Thr 286 during S phase leads to its proteasomal degradation and allows efficient DNA synthesisQ42817675
Mantle-cell lymphoma genotypes identified with CGH to BAC microarrays define a leukemic subgroup of disease and predict patient outcomeQ44730863
The translation factor eIF-4E promotes tumor formation and cooperates with c-Myc in lymphomagenesisQ44851701
Immunohistochemical analysis of ZAP-70 expression in B-cell lymphoid neoplasmsQ45247281
Suppression of phosphatidylinositol 3-kinase/Akt signaling pathway is a determinant of the sensitivity to a novel histone deacetylase inhibitor, FK228, in lung adenocarcinoma cells.Q45261602
The mTOR inhibitor RAD001 sensitizes tumor cells to DNA-damaged induced apoptosis through inhibition of p21 translation.Q46410011
The molecular signature of mantle cell lymphoma reveals multiple signals favoring cell survival.Q47316124
Frequent inactivation of PTEN in prostate cancer cell lines and xenograftsQ47855108
Mantle cell lymphoma proliferates upon IL-10 in the CD40 system.Q54040698
Gene expression profiling of mantle cell lymphoma cells reveals aberrant expression of genes from the PI3K-AKT, WNT and TGFbeta signalling pathways.Q54648964
CDK4andMDM2Gene Alterations Mainly Occur in Highly Proliferative and Aggressive Mantle Cell Lymphomas with Wild-typeINK4a/ARFLocusQ57279470
Altered apoptosis pathways in mantle cell lymphoma detected by oligonucleotide microarrayQ74250057
Novel chromosomal imbalances in mantle cell lymphoma detected by genome-wide array-based comparative genomic hybridizationQ80894677
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectmantle cell lymphomaQ268713
P304page(s)2667-2673
P577publication date2007-07-02
P1433published inBloodQ885070
P1476titleSuberoylanilide hydroxamic acid (SAHA; vorinostat) suppresses translation of cyclin D1 in mantle cell lymphoma cells
P478volume110