Deficient vesicular storage: A common theme in catecholaminergic neurodegeneration.

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Deficient vesicular storage: A common theme in catecholaminergic neurodegeneration. is …
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scholarly articleQ13442814

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P356DOI10.1016/J.PARKRELDIS.2015.07.009
P932PMC publication ID4554767
P698PubMed publication ID26255205
P5875ResearchGate publication ID280910121

P50authorDeborah MashQ545893
Alessandro StefaniQ56418196
Irwin J KopinQ85857575
P2093author name stringEllen Sidransky
David S Goldstein
Patti Sullivan
Courtney Holmes
Yehonatan Sharabi
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Simple ratio analysis of 18F-fluorodopa uptake in striatal subregions separates patients with early Parkinson disease from healthy controls.Q46011395
Profound cardiac sympathetic denervation occurs in Parkinson diseaseQ46392026
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Central dopamine deficiency in pure autonomic failureQ46685407
Unregulated cytosolic dopamine causes neurodegeneration associated with oxidative stress in miceQ46815723
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Dopamine oxidation alters mitochondrial respiration and induces permeability transition in brain mitochondria: implications for Parkinson's diseaseQ48127846
???Q64865235
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Relation of plasma norepinephrine and sympathetic traffic during hypotension in humansQ28334771
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Aggregation of alpha-synuclein by DOPAL, the monoamine oxidase metabolite of dopamineQ33344779
Reduced vesicular storage of catecholamines causes progressive degeneration in the locus ceruleusQ33724885
Divalent metal ions enhance DOPAL-induced oligomerization of alpha-synuclein.Q33771253
Determinants of buildup of the toxic dopamine metabolite DOPAL in Parkinson's diseaseQ33896138
The neuropathic postural tachycardia syndromeQ33920200
Renin-aldosterone paradox and perturbed blood volume regulation underlying postural tachycardia syndrome.Q33985907
Hypertension increases cerebral 6-18F-fluorodopa-derived radioactivityQ34182833
Clinical laboratory evaluation of autoimmune autonomic ganglionopathy: Preliminary observationsQ34182853
Intracellular patch electrochemistry: regulation of cytosolic catecholamines in chromaffin cells.Q34211646
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Partial cardiac sympathetic denervation after bilateral thoracic sympathectomy in humansQ34422109
Glial cytoplasmic inclusions in the CNS of patients with multiple system atrophy (striatonigral degeneration, olivopontocerebellar atrophy and Shy-Drager syndrome).Q34458365
A vesicular sequestration to oxidative deamination shift in myocardial sympathetic nerves in Parkinson's diseaseQ34560077
In vivo demonstration that alpha-synuclein oligomers are toxicQ34652122
Characterization of reduced and oxidized dopamine and 3,4-dihydrophenylacetic acid, on brain mitochondrial electron transport chain activitiesQ35024921
Oxidation of 3,4-dihydroxyphenylacetaldehyde, a toxic dopaminergic metabolite, to a semiquinone radical and an ortho-quinone.Q35128313
Intra-neuronal vesicular uptake of catecholamines is decreased in patients with Lewy body diseasesQ35142854
(123)I-metaiodobenzylguanidine myocardial scintigraphy in Parkinson's diseaseQ35452165
Decreased vesicular storage and aldehyde dehydrogenase activity in multiple system atrophyQ35638948
Impaired neurotransmission caused by overexpression of α-synuclein in nigral dopamine neuronsQ35807528
Cerebrospinal fluid biomarkers of central catecholamine deficiency in Parkinson's disease and other synucleinopathiesQ35986671
Alterations in axonal transport motor proteins in sporadic and experimental Parkinson's diseaseQ36063269
Catechols in post-mortem brain of patients with Parkinson diseaseQ36086433
Sympathetic neurocirculatory failure in Parkinson disease: Evidence for an etiologic role of alpha-synucleinQ36100326
The neurobiology of glucocerebrosidase-associated parkinsonism: a positron emission tomography study of dopamine synthesis and regional cerebral blood flowQ36124421
P433issue9
P921main subjectneurodegenerationQ1755122
P1104number of pages10
P304page(s)1013-1022
P577publication date2015-07-17
P1433published inParkinsonism and Related DisordersQ15762600
P1476titleDeficient vesicular storage: A common theme in catecholaminergic neurodegeneration
P478volume21

Reverse relations

cites work (P2860)
Q91862580Alpha-Synuclein Deposition Within Sympathetic Noradrenergic Neurons Is Associated With Myocardial Noradrenergic Deficiency in Neurogenic Orthostatic Hypotension
Q99566885Cardiac sympathetic innervation and vesicular storage in pure autonomic failure
Q92118440Computational modeling reveals multiple abnormalities of myocardial noradrenergic function in Lewy body diseases
Q47377298Does sympathetic dysfunction occur before denervation in pure autonomic failure?
Q41655727Elevated cerebrospinal fluid ratios of cysteinyl-dopamine/3,4-dihydroxyphenylacetic acid in parkinsonian synucleinopathies
Q41927560Genetic elimination of dopamine vesicular stocks in the nigrostriatal pathway replicates Parkinson's disease motor symptoms without neuronal degeneration in adult mice.
Q64859931Imaging the Autonomic Nervous System in Parkinson's Disease
Q96953378Increased Noradrenaline as an Additional Cerebrospinal Fluid Biomarker in PSP-Like Parkinsonism
Q39294770Linking Stress, Catecholamine Autotoxicity, and Allostatic Load with Neurodegenerative Diseases: A Focused Review in Memory of Richard Kvetnansky
Q48313756Pure autonomic failure without synucleinopathy
Q49490658Tyrosine Hydroxylase, Vesicular Monoamine Transporter and Dopamine Transporter mRNA Expression in Nigrostriatal Tissue of Rats with Pedunculopontine Neurotoxic Lesion

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