Genetic architecture of microRNA expression: implications for the transcriptome and complex traits

scientific article

Genetic architecture of microRNA expression: implications for the transcriptome and complex traits is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.AJHG.2012.04.023
P932PMC publication ID3370272
P698PubMed publication ID22658545
P5875ResearchGate publication ID225096921

P50authorNancy J CoxQ67954217
Eric R. GamazonQ37616152
Hae Kyung ImQ47327124
P2093author name stringR Stephanie Huang
Dana Ziliak
Bonnie LaCroix
Danny S Park
P2860cites workDNA methylation patterns associate with genetic and gene expression variation in HapMap cell linesQ21184030
Polymorphisms in the estrogen receptor 1 and vitamin C and matrix metalloproteinase gene families are associated with susceptibility to lymphomaQ21562611
Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWASQ21563317
Genome-wide identification of SNPs in microRNA genes and the SNP effects on microRNA target binding and biogenesisQ82299247
Potential etiologic and functional implications of genome-wide association loci for human diseases and traitsQ22066284
The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteinsQ24318187
miRBase: microRNA sequences, targets and gene nomenclatureQ24538656
A map of human genome variation from population-scale sequencingQ24617794
New loci associated with kidney function and chronic kidney diseaseQ24630646
A second generation human haplotype map of over 3.1 million SNPsQ24651939
Most mammalian mRNAs are conserved targets of microRNAsQ24655061
PolymiRTS Database: linking polymorphisms in microRNA target sites with complex traitsQ24675631
A miR-24 microRNA binding-site polymorphism in dihydrofolate reductase gene leads to methotrexate resistanceQ24679991
Statistical significance for genomewide studiesQ24681264
Combinatorial microRNA target predictionsQ27860510
MicroRNA gene expression deregulation in human breast cancerQ27860690
The International HapMap ProjectQ27860695
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resourcesQ27860739
Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene listsQ28131785
CpG-rich islands and the function of DNA methylationQ28131800
A defect in the Kv channel-interacting protein 2 (KChIP2) gene leads to a complete loss of I(to) and confers susceptibility to ventricular tachycardiaQ28211696
The let-7 microRNA represses cell proliferation pathways in human cellsQ28240833
Let-7 prevents early cancer progression by suppressing expression of the embryonic gene HMGA2Q28254493
Posttranscriptional regulation of microRNA biogenesis in animalsQ28282519
Genetic variation in the sodium-dependent vitamin C transporters, SLC23A1, and SLC23A2 and risk for preterm deliveryQ28287147
Genetic variation in the vitamin C transporter, SLC23A2, modifies the risk of HPV16-associated head and neck cancerQ28389041
Genetic analysis of human traits in vitro: drug response and gene expression in lymphoblastoid cell linesQ28474104
Mixed effects modeling of proliferation rates in cell-based models: consequence for pharmacogenomics and cancerQ28480587
Specificity of microRNA target selection in translational repressionQ28776123
Genomewide association study for onset age in Parkinson diseaseQ29417034
Understanding mechanisms underlying human gene expression variation with RNA sequencingQ29614412
Transcriptome genetics using second generation sequencing in a Caucasian populationQ29614413
Population genomics of human gene expressionQ29614905
Gene silencing by microRNAs: contributions of translational repression and mRNA decayQ29615825
MicroRNA-378 targets the myogenic repressor MyoR during myoblast differentiationQ30426550
PARK3 influences age at onset in Parkinson disease: a genome scan in the GenePD studyQ30448742
A genome-wide approach to identify genetic variants that contribute to etoposide-induced cytotoxicity.Q30479559
miRNA malfunction causes spinal motor neuron diseaseQ30495998
A genome-wide survey for SNPs altering microRNA seed sites identifies functional candidates in GWAS.Q31034509
MicroRNA-133a protects against myocardial fibrosis and modulates electrical repolarization without affecting hypertrophy in pressure-overloaded adult heartsQ33580704
Patrocles: a database of polymorphic miRNA-mediated gene regulation in vertebratesQ33601105
SCAN: SNP and copy number annotationQ33779644
The landscape of genetic complexity across 5,700 gene expression traits in yeastQ33818641
The Influence of 3'UTRs on MicroRNA Function Inferred from Human SNP DataQ34081307
Genetic loci influencing kidney function and chronic kidney diseaseQ34109552
Downregulation of microRNA-200 in EBV-associated gastric carcinomaQ34116271
Genetic variation in microRNA networks: the implications for cancer researchQ34177121
Heritable and non-genetic factors as variables of pharmacologic phenotypes in lymphoblastoid cell linesQ34288272
Genetic variation in sodium-dependent vitamin C transporters SLC23A1 and SLC23A2 and risk of advanced colorectal adenomaQ34657155
A comparison of background correction methods for two-colour microarraysQ34667581
A genome-wide approach identifies that the aspartate metabolism pathway contributes to asparaginase sensitivity.Q34989475
Inferring causative variants in microRNA target sitesQ35198281
Population differences in microRNA expression and biological implicationsQ35578546
Identification of genetic variants contributing to cisplatin-induced cytotoxicity by use of a genomewide approachQ35946327
Evaluation of genetic variation contributing to differences in gene expression between populationsQ36718956
Genetic architecture of transcript-level variation in humansQ37118371
Effect of population and gender on chemotherapeutic agent-induced cytotoxicityQ37159518
The database of experimentally supported targets: a functional update of TarBaseQ37202497
Genetic variants contributing to daunorubicin-induced cytotoxicityQ37271466
Genetic variants associated with carboplatin-induced cytotoxicity in cell lines derived from Africans.Q37344425
Genetic variation in sodium-dependent ascorbic acid transporters and risk of gastric cancer in PolandQ37354850
Discovery and genotyping of genome structural polymorphism by sequencing on a population scaleQ37390913
Small RNAs are on the move.Q37791829
MicroRNA gene expression during retinoic acid-induced differentiation of human acute promyelocytic leukemia.Q38305314
MicroRNAs play an essential role in the development of cardiac hypertrophyQ39340872
The effects of EBV transformation on gene expression levels and methylation profilesQ39598932
Epstein-Barr virus encoded LMP1 downregulates TCL1 oncogene through miR-29bQ39766210
The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-alpha (ERalpha) and represses ERalpha messenger RNA and protein expression in breast cancer cell lines.Q40168734
Modulation of cholinephosphotransferase activity in breast cancer cell lines by Ro5-4864, a peripheral benzodiazepine receptor agonistQ40413401
KChIP2 attenuates cardiac hypertrophy through regulation of Ito and intracellular calcium signaling.Q40447179
Mapping of the human genes (SLC23A2 and SLC23A1) coding for vitamin C transporters 1 and 2 (SVCT1 and SVCT2) to 5q23 and 20p12, respectivelyQ43075692
P433issue6
P407language of work or nameEnglishQ1860
P921main subjecttranscriptomeQ252857
complex traitQ55608248
microRNA expressionQ60681249
P304page(s)1046-1063
P577publication date2012-05-31
P1433published inAmerican Journal of Human GeneticsQ4744249
P1476titleGenetic architecture of microRNA expression: implications for the transcriptome and complex traits
P478volume90