| scholarly article | Q13442814 |
| P50 | author | Angela L. Tyner | Q40425349 |
| P2093 | author name string | M Peng | |
| S M Ball-Kell | |||
| P2860 | cites work | Mouse estrous cycle identification tool and images | Q21004106 |
| BCAR1, a human homologue of the adapter protein p130Cas, and antiestrogen resistance in breast cancer cells | Q22011095 | ||
| Regulation of the nonreceptor tyrosine kinase Brk by autophosphorylation and by autoinhibition | Q24301621 | ||
| Identification of STAT3 as a specific substrate of breast tumor kinase | Q24311267 | ||
| FAK in cancer: mechanistic findings and clinical applications | Q27026533 | ||
| P130Cas Src-Binding and Substrate Domains Have Distinct Roles in Sustaining Focal Adhesion Disassembly and Promoting Cell Migration | Q27318059 | ||
| Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene | Q27860693 | ||
| Protein-tyrosine kinase 6 promotes peripheral adhesion complex formation and cell migration by phosphorylating p130 CRK-associated substrate | Q28115210 | ||
| Brk is coamplified with ErbB2 to promote proliferation in breast cancer | Q28115616 | ||
| Dangerous liaisons: STAT3 and NF-kappaB collaboration and crosstalk in cancer | Q28267996 | ||
| p130Cas is an essential transducer element in ErbB2 transformation | Q28283561 | ||
| Protein tyrosine kinase 6 negatively regulates growth and promotes enterocyte differentiation in the small intestine | Q28509681 | ||
| Quantitative association between HER-2/neu and steroid hormone receptors in hormone receptor-positive primary breast cancer | Q44279198 | ||
| p130Cas as a new regulator of mammary epithelial cell proliferation, survival, and HER2-neu oncogene-dependent breast tumorigenesis. | Q53346696 | ||
| BRK tyrosine kinase expression in a high proportion of human breast carcinomas | Q73615071 | ||
| Estrous cycle regulation of mammary epithelial cell proliferation, differentiation, and death in the Sprague-Dawley rat: a model for investigating the role of estrous cycling in mammary carcinogenesis | Q28576222 | ||
| Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer | Q29547699 | ||
| Breast tumor kinase (protein tyrosine kinase 6) regulates heregulin-induced activation of ERK5 and p38 MAP kinases in breast cancer cells | Q33283847 | ||
| PTK6 Regulates IGF-1-Induced Anchorage-Independent Survival | Q33644326 | ||
| Identification of a Stat3-dependent transcription regulatory network involved in metastatic progression. | Q33740488 | ||
| Building a better understanding of the intracellular tyrosine kinase PTK6 - BRK by BRK | Q33912469 | ||
| HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression | Q33968465 | ||
| HIF-1α-independent hypoxia-induced rapid PTK6 stabilization is associated with increased motility and invasion | Q34036107 | ||
| PTK6/BRK is expressed in the normal mammary gland and activated at the plasma membrane in breast tumors | Q34227580 | ||
| Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene | Q34560337 | ||
| Breast tumor kinase (Brk/PTK6) is a mediator of hypoxia-associated breast cancer progression. | Q34912116 | ||
| The unholy trinity: inflammation, cytokines, and STAT3 shape the cancer microenvironment | Q35034370 | ||
| Inhibition of Lapatinib-Induced Kinome Reprogramming in ERBB2-Positive Breast Cancer by Targeting BET Family Bromodomains | Q35533503 | ||
| PTK6 inhibition promotes apoptosis of Lapatinib-resistant Her2(+) breast cancer cells by inducing Bim. | Q35834635 | ||
| Protein Tyrosine Kinase 6 Regulates UVB-Induced Signaling and Tumorigenesis in Mouse Skin | Q36054456 | ||
| Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression | Q36299911 | ||
| Resistance to Trastuzumab in Breast Cancer. | Q36318226 | ||
| Focal adhesion kinase contributes to proliferative potential of ErbB2 mammary tumour cells but is dispensable for ErbB2 mammary tumour induction in vivo | Q36393238 | ||
| Brk/PTK6 cooperates with HER2 and Src in regulating breast cancer cell survival and epithelial-to-mesenchymal transition | Q36677706 | ||
| The oncogene HER2/neu (ERBB2) requires the hypoxia-inducible factor HIF-1 for mammary tumor growth and anoikis resistance | Q36890663 | ||
| HER2 regulates Brk/PTK6 stability via upregulating calpastatin, an inhibitor of calpain | Q36989525 | ||
| Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling. | Q37073729 | ||
| Induction of protein tyrosine kinase 6 in mouse intestinal crypt epithelial cells promotes DNA damage-induced apoptosis | Q37399415 | ||
| Protein tyrosine kinase 6 regulates mammary gland tumorigenesis in mouse models. | Q37614521 | ||
| Evolving novel anti-HER2 strategies | Q37643985 | ||
| Additive impact of HER2-/PTK6-RNAi on interactions with HER3 or IGF-1R leads to reduced breast cancer progression in vivo. | Q38954660 | ||
| STAT3 signaling is activated preferentially in tumor-initiating cells in claudin-low models of human breast cancer | Q38988872 | ||
| Effects of simultaneous knockdown of HER2 and PTK6 on malignancy and tumor progression in human breast cancer cells | Q39201899 | ||
| Protein tyrosine kinase 6 protects cells from anoikis by directly phosphorylating focal adhesion kinase and activating AKT. | Q39268132 | ||
| Disruption of the mouse protein tyrosine kinase 6 gene prevents STAT3 activation and confers resistance to azoxymethane | Q39509825 | ||
| Impact of protein tyrosine kinase 6 (PTK6) on human epidermal growth factor receptor (HER) signalling in breast cancer. | Q39580432 | ||
| Stat3 is required for anchorage-independent growth and metastasis but not for mammary tumor development downstream of the ErbB-2 oncogene | Q39760250 | ||
| p130Cas substrate domain signaling promotes migration, invasion, and survival of estrogen receptor-negative breast cancer cells. | Q39900183 | ||
| Stat3 is required for the development of skin cancer | Q39951270 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P304 | page(s) | e1848 | |
| P577 | publication date | 2015-08-06 | |
| P1433 | published in | Cell Death and Disease | Q2197222 |
| P1476 | title | Protein tyrosine kinase 6 promotes ERBB2-induced mammary gland tumorigenesis in the mouse | |
| P478 | volume | 6 |
| Q45318098 | ERBB2 Activates PTK6 Signaling |
| Q54120207 | Genome-Wide Identification and Characterization of Tyrosine Kinases in the Silkworm, Bombyx mori. |
| Q38618837 | Identification and characterization of tyrosine kinases in anole lizard indicate the conserved tyrosine kinase repertoire in vertebrates. |
| Q37017273 | Kinase-Dependent and -Independent Roles for PTK6 in Colon Cancer |
| Q36310690 | Mammary epithelial cell phenotype disruption in vitro and in vivo through ERalpha36 overexpression |
| Q45904675 | PTEN is a protein phosphatase that targets active PTK6 and inhibits PTK6 oncogenic signaling in prostate cancer. |
| Q45318326 | Signaling by PTK6 |
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