| scholarly article | Q13442814 |
| P50 | author | Bruce A Edgar | Q90321020 |
| P2093 | author name string | Tao Wang | |
| Ying Kuo | |||
| Rachel Blumhagen | |||
| Uyen Lao | |||
| P2860 | cites work | Activation of mTORC2 by Association with the Ribosome | Q24294876 |
| Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex | Q24295120 | ||
| Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton | Q24299873 | ||
| Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action | Q24302566 | ||
| mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide | Q24305343 | ||
| Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive | Q24306328 | ||
| Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids | Q24306330 | ||
| P-Rex1 links mammalian target of rapamycin signaling to Rac activation and cell migration | Q24310060 | ||
| Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control | Q24314363 | ||
| The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1 | Q24315566 | ||
| mTOR: from growth signal integration to cancer, diabetes and ageing | Q24633662 | ||
| Characterization of Rictor phosphorylation sites reveals direct regulation of mTOR complex 2 by S6K1 | Q24645183 | ||
| Rictor/TORC2 regulates Caenorhabditis elegans fat storage, body size, and development through sgk-1 | Q27331645 | ||
| TOR signaling in growth and metabolism | Q27860757 | ||
| LST8 negatively regulates amino acid biosynthesis as a component of the TOR pathway | Q27930185 | ||
| TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling | Q28131740 | ||
| Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins | Q28207283 | ||
| Localization of Rheb to the endomembrane is critical for its signaling function | Q28235946 | ||
| Rheb binds and regulates the mTOR kinase | Q28247033 | ||
| SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity | Q28262782 | ||
| Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1 | Q28276788 | ||
| Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability | Q28504594 | ||
| The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins | Q28507365 | ||
| Role and regulation of starvation-induced autophagy in the Drosophila fat body | Q29617035 | ||
| Akt regulates growth by directly phosphorylating Tsc2 | Q29620397 | ||
| Control of Amino Acid Permease Sorting in the Late Secretory Pathway of Saccharomyces cerevisiae by SEC13, LST4, LST7 and LST78 | Q33971473 | ||
| Critical roles for mTORC2- and rapamycin-insensitive mTORC1-complexes in growth and survival of BCR-ABL-expressing leukemic cells | Q34004994 | ||
| Rheb promotes cell growth as a component of the insulin/TOR signalling network | Q34199893 | ||
| TSC1/TSC2 and Rheb have different effects on TORC1 and TORC2 activity | Q34598209 | ||
| A genetic method for generating Drosophila eyes composed exclusively of mitotic clones of a single genotype. | Q34607330 | ||
| Evidence for direct activation of mTORC2 kinase activity by phosphatidylinositol 3,4,5-trisphosphate | Q34719423 | ||
| Ends-out, or replacement, gene targeting in Drosophila | Q34807177 | ||
| Regulation of cellular growth by the Drosophila target of rapamycin dTOR | Q35206467 | ||
| mTOR complex 2 signaling and functions | Q35878519 | ||
| Abnormal glutamate homeostasis and impaired synaptic plasticity and learning in a mouse model of tuberous sclerosis complex | Q36226071 | ||
| Dissecting independent channel and scaffolding roles of the Drosophila transient receptor potential channel | Q36321035 | ||
| Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans | Q37111299 | ||
| Signaling events downstream of mammalian target of rapamycin complex 2 are attenuated in cells and tumors deficient for the tuberous sclerosis complex tumor suppressors | Q37326084 | ||
| TOR-mediated autophagy regulates cell death in Drosophila neurodegenerative disease | Q37342465 | ||
| Structure of the human mTOR complex I and its implications for rapamycin inhibition. | Q39694102 | ||
| Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner | Q39707409 | ||
| Rictor is a novel target of p70 S6 kinase-1. | Q39771171 | ||
| Re-evaluating AKT regulation: role of TOR complex 2 in tissue growth | Q41837867 | ||
| Amino acids activate mammalian target of rapamycin complex 2 (mTORC2) via PI3K/Akt signaling | Q42006441 | ||
| Rheb is an essential regulator of S6K in controlling cell growth in Drosophila | Q44453753 | ||
| Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies | Q45067792 | ||
| Flow cytometric analysis of Drosophila cells | Q46472655 | ||
| A nutrient sensor mechanism controls Drosophila growth. | Q47070296 | ||
| A phosphoinositide synthase required for a sustained light response. | Q47070689 | ||
| Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size | Q47211341 | ||
| Structure of TOR and Its Complex with KOG1 | Q58660086 | ||
| Expression of ICAM-1, TNF-alpha, NF kappa B, and MAP kinase in tubers of the tuberous sclerosis complex | Q79195309 | ||
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cell growth | Q189159 |
| Raptor Dmel_CG4320 | Q29812250 | ||
| Lst8 Dmel_CG3004 | Q29817170 | ||
| Ras homolog enriched in brain Dmel_CG1081 | Q29817933 | ||
| Tsc1 Dmel_CG6147 | Q29818026 | ||
| Target of rapamycin Dmel_CG5092 | Q51235924 | ||
| P304 | page(s) | 2203-2213 | |
| P577 | publication date | 2012-04-09 | |
| P1433 | published in | Molecular and Cellular Biology | Q3319478 |
| P1476 | title | LST8 regulates cell growth via target-of-rapamycin complex 2 (TORC2). | |
| P478 | volume | 32 |
| Q46169318 | Development of a tissue-specific ribosome profiling approach in Drosophila enables genome-wide evaluation of translational adaptations. |
| Q36733239 | SKN-1/Nrf, stress responses, and aging in Caenorhabditis elegans |
| Q38700659 | Signaling crosstalk between the mTOR complexes |
| Q37299616 | Suppression of polyglutamine protein toxicity by co-expression of a heat-shock protein 40 and a heat-shock protein 110 |
| Q35878104 | TORC2 mediates the heat stress response in Drosophila by promoting the formation of stress granules |
| Q37424724 | TORC2 signaling antagonizes SKN-1 to induce C. elegans mesendodermal embryonic development |
| Q40963188 | Target of Rapamycin Complex 2 regulates cell growth via Myc in Drosophila |
| Q30235555 | The Complex Roles of Mechanistic Target of Rapamycin in Adipocytes and Beyond |
| Q38714678 | The TOR Signaling Pathway in Spatial and Temporal Control of Cell Size and Growth |
| Q42741621 | WAC Regulates mTOR Activity by Acting as an Adaptor for the TTT and Pontin/Reptin Complexes |
| Q47944047 | dTBC1D7 regulates systemic growth independently of TSC through insulin signaling. |
| Q38073906 | mTOR in aging, metabolism, and cancer |
| Q35209468 | mTORC2-SGK-1 acts in two environmentally responsive pathways with opposing effects on longevity |
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