| scholarly article | Q13442814 |
| P356 | DOI | 10.1007/S11306-015-0772-0 |
| P2888 | exact match | https://scigraph.springernature.com/pub.10.1007/s11306-015-0772-0 |
| P932 | PMC publication ID | 4559110 |
| P698 | PubMed publication ID | 26366134 |
| P5875 | ResearchGate publication ID | 271325182 |
| P50 | author | Andras Perl | Q38328717 |
| P2093 | author name string | John M Asara | |
| Ryan Kelly | |||
| Zachary Oaks | |||
| Zhi-Wei Lai | |||
| Paul E Phillips | |||
| Robert Hanczko | |||
| Rebecca Borsuk | |||
| P2860 | cites work | Functional characterization and mechanism of action of recombinant human kynurenine 3-hydroxylase | Q22253175 |
| A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1 | Q24294219 | ||
| mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery | Q24302549 | ||
| MetaboAnalyst 2.0--a comprehensive server for metabolomic data analysis | Q24632755 | ||
| Glutathione synthesis | Q26864265 | ||
| Mitochondrial hyperpolarization and ATP depletion in patients with systemic lupus erythematosus | Q28216909 | ||
| Redox regulation of the nutrient-sensitive raptor-mTOR pathway and complex | Q28273915 | ||
| Imbalance of Th1/Th2 transcription factors in patients with lupus nephritis. | Q54619147 | ||
| Short-term control of the pentose phosphate cycle by insulin could be modulated by the NADPHNADP ratio in rat adipocytes and hepatocytes | Q59651011 | ||
| BILAG 2004. Development and initial validation of an updated version of the British Isles Lupus Assessment Group's disease activity index for patients with systemic lupus erythematosus | Q60699961 | ||
| Psychometric qualities of a brief self-rated fatigue measure: The Fatigue Assessment Scale | Q73204607 | ||
| Association between T lymphocyte sub-sets apoptosis and peripheral blood mononuclear cells oxidative stress in systemic lupus erythematosus | Q83339044 | ||
| Web-based inference of biological patterns, functions and pathways from metabolomic data using MetaboAnalyst | Q28746102 | ||
| Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus | Q29614922 | ||
| Oxidative stress in the pathology and treatment of systemic lupus erythematosus | Q33715508 | ||
| Increased mitochondrial electron transport chain activity at complex I is regulated by N-acetylcysteine in lymphocytes of patients with systemic lupus erythematosus | Q33722895 | ||
| UVA light-excited kynurenines oxidize ascorbate and modify lens proteins through the formation of advanced glycation end products: implications for human lens aging and cataract formation | Q33761317 | ||
| Oxidative stress, T cell DNA methylation, and lupus | Q34077487 | ||
| Amino acid signalling upstream of mTOR | Q34325138 | ||
| Mechanistic target of rapamycin activation triggers IL-4 production and necrotic death of double-negative T cells in patients with systemic lupus erythematosus | Q34361763 | ||
| Mechanistic target of rapamycin complex 1 expands Th17 and IL-4+ CD4-CD8- double-negative T cells and contracts regulatory T cells in systemic lupus erythematosus | Q34412837 | ||
| Cysteine/cystine redox signaling in cardiovascular disease | Q34580141 | ||
| Transaldolase deficiency influences the pentose phosphate pathway, mitochondrial homoeostasis and apoptosis signal processing | Q34656352 | ||
| Expanded double negative T cells in patients with systemic lupus erythematosus produce IL-17 and infiltrate the kidneys | Q34892862 | ||
| Activation of mammalian target of rapamycin controls the loss of TCRzeta in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation | Q34939946 | ||
| Oxidative stress, inflammation and carcinogenesis are controlled through the pentose phosphate pathway by transaldolase | Q35048149 | ||
| Isoprenoids: remarkable diversity of form and function | Q35882448 | ||
| N-acetylcysteine reduces disease activity by blocking mammalian target of rapamycin in T cells from systemic lupus erythematosus patients: a randomized, double-blind, placebo-controlled trial | Q36139749 | ||
| Regulation and function of mTOR signalling in T cell fate decisions | Q36157753 | ||
| Regular consumption of black tea increases circulating kynurenine concentrations: A randomized controlled trial. | Q36323806 | ||
| A positive/negative ion-switching, targeted mass spectrometry-based metabolomics platform for bodily fluids, cells, and fresh and fixed tissue | Q36937203 | ||
| Prevention of hepatocarcinogenesis and increased susceptibility to acetaminophen-induced liver failure in transaldolase-deficient mice by N-acetylcysteine | Q37209229 | ||
| Molecular mechanisms of homocysteine toxicity | Q37567866 | ||
| cAMP inhibits mammalian target of rapamycin complex-1 and -2 (mTORC1 and 2) by promoting complex dissociation and inhibiting mTOR kinase activity. | Q38657890 | ||
| A multilevel layout algorithm for visualizing physical and genetic interaction networks, with emphasis on their modular organization | Q39636559 | ||
| Inhibition of tumor cell growth by interferon-gamma is mediated by two distinct mechanisms dependent upon oxygen tension: induction of tryptophan degradation and depletion of intracellular nicotinamide adenine dinucleotide | Q40511488 | ||
| A Pulse-radiolysis Study of the Reaction of Hydrated Electrons with N′-formylkynurenine and Related Compounds: Electron-transfer Reactions with Nucleic Acid Components | Q40651747 | ||
| Stimulation of de novo pyrimidine synthesis by growth signaling through mTOR and S6K1. | Q41983843 | ||
| Protection of vascular smooth muscle cells by over-expressed methionine sulphoxide reductase A: role of intracellular localization and substrate availability | Q42446607 | ||
| Screening methods to identify indole derivatives that protect against reactive oxygen species induced tryptophan oxidation in proteins | Q43613341 | ||
| T cell receptor alpha/beta expressing double-negative (CD4-/CD8-) and CD4+ T helper cells in humans augment the production of pathogenic anti-DNA autoantibodies associated with lupus nephritis | Q44381577 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 5 | |
| P921 | main subject | systemic lupus erythematosus | Q1485 |
| sirolimus | Q32089 | ||
| P304 | page(s) | 1157-1174 | |
| P577 | publication date | 2015-01-20 | |
| P1433 | published in | Metabolomics | Q15764355 |
| P1476 | title | Comprehensive metabolome analyses reveal N-acetylcysteine-responsive accumulation of kynurenine in systemic lupus erythematosus: implications for activation of the mechanistic target of rapamycin | |
| P478 | volume | 11 |
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| Q57034075 | Shotgun Lipidomics Revealed Altered Profiles of Serum Lipids in Systemic Lupus Erythematosus Closely Associated with Disease Activity |
| Q52650139 | Sirolimus in patients with clinically active systemic lupus erythematosus resistant to, or intolerant of, conventional medications: a single-arm, open-label, phase 1/2 trial. |
| Q96303611 | T Cell Metabolism: A New Perspective on Th17/Treg Cell Imbalance in Systemic Lupus Erythematosus |
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