Proteolytic Cleavage of the Plasmodium falciparum Circumsporozoite Protein Is a Target of Protective Antibodies

scientific article

Proteolytic Cleavage of the Plasmodium falciparum Circumsporozoite Protein Is a Target of Protective Antibodies is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/INFDIS/JIV154
P932PMC publication ID4559189
P698PubMed publication ID25762791

P50authorDiego A EspinosaQ56323572
Gabriel M GutierrezQ56797438
Maricarmen Rojas-LópezQ60633914
P2093author name stringPhotini Sinnis
Lirong Shi
Fidel Zavala
Sze-Wah Tse
Amy R Noe
P2860cites workA phase 3 trial of RTS,S/AS01 malaria vaccine in African infantsQ28278852
Circumsporozoite-specific T cell responses in children vaccinated with RTS,S/AS01E and protection against P falciparum clinical malariaQ28744170
Insights into long-lasting protection induced by RTS,S/AS02A malaria vaccine: further results from a phase IIb trial in Mozambican childrenQ33430011
Binding and invasion of liver cells by Plasmodium falciparum sporozoites. Essential involvement of the amino terminus of circumsporozoite proteinQ33956518
The Plasmodium circumsporozoite protein is proteolytically processed during cell invasionQ33984183
Safety and efficacy of the RTS, S/AS01 E candidate malaria vaccine given with expanded-programme-on-immunisation vaccines: 19 month follow-up of a randomised, open-label, phase 2 trialQ34202910
A full-length Plasmodium falciparum recombinant circumsporozoite protein expressed by Pseudomonas fluorescens platform as a malaria vaccine candidateQ34232909
The malaria circumsporozoite protein has two functional domains, each with distinct roles as sporozoites journey from mosquito to mammalian hostQ34577701
Dendritic cells and hepatocytes use distinct pathways to process protective antigen from plasmodium in vivoQ34693251
Randomized, double-blind, phase 2a trial of falciparum malaria vaccines RTS,S/AS01B and RTS,S/AS02A in malaria-naive adults: safety, efficacy, and immunologic associates of protectionQ34990090
Synthetic peptide vaccine confers protection against murine malariaQ36357591
Development of a chimeric Plasmodium berghei strain expressing the repeat region of the P. vivax circumsporozoite protein for in vivo evaluation of vaccine efficacyQ37036065
Gene targeting in malaria parasitesQ44138096
Detection of malaria liver-stages in mice infected through the bite of a single Anopheles mosquito using a highly sensitive real-time PCR.Q44146651
Cutting edge: a new tool to evaluate human pre-erythrocytic malaria vaccines: rodent parasites bearing a hybrid Plasmodium falciparum circumsporozoite proteinQ44149714
The N-terminal domain of Plasmodium falciparum circumsporozoite protein represents a target of protective immunityQ44888648
An immunologically cryptic epitope of Plasmodium falciparum circumsporozoite protein facilitates liver cell recognition and induces protective antibodies that block liver cell invasionQ44909377
First results of phase 3 trial of RTS,S/AS01 malaria vaccine in African childrenQ46182948
Rationale for development of a synthetic vaccine against plasmodium falciparum malariaQ47886490
Cloned cytotoxic T cells recognize an epitope in the circumsporozoite protein and protect against malariaQ47888641
Hybridoma produces protective antibodies directed against the sporozoite stage of malaria parasiteQ47989675
Synthesis and immunological characterization of 104-mer and 102-mer peptides corresponding to the N- and C-terminal regions of the Plasmodium falciparum CS proteinQ48027464
P4510describes a project that usesImageJQ1659584
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectproteolysisQ33123
Plasmodium falciparumQ311383
circumsporozoite (CS) proteinQ56558934
P304page(s)1111-1119
P577publication date2015-03-11
P1433published inJournal of Infectious DiseasesQ4051141
P1476titleProteolytic Cleavage of the Plasmodium falciparum Circumsporozoite Protein Is a Target of Protective Antibodies
P478volume212

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cites work (P2860)
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