| scholarly article | Q13442814 |
| P50 | author | Ryusuke Yoshimi | Q42974651 |
| P2093 | author name string | Yoshiaki Ishigatsubo | |
| Keiko Ozato | |||
| P2860 | cites work | STAT1-dependent and STAT1-independent gene expression in murine immune cells following stimulation with interferon-alpha | Q80337505 |
| B cell depletion as a novel treatment for systemic lupus erythematosus: a phase I/II dose-escalation trial of rituximab | Q80502406 | ||
| SSA/Ro52 autoantigen interacts with Dcp2 to enhance its decapping activity | Q80941814 | ||
| In situ glomerular expression of activated NF-kappaB in human lupus nephritis and other non-proliferative proteinuric glomerulopathy | Q81311956 | ||
| Intracellular antibody-mediated immunity and the role of TRIM21 | Q82069556 | ||
| Diagnostic utility of anti-Ro52 detection in systemic autoimmunity | Q82846585 | ||
| Genetic deficiency of C4, C2 or C1q and lupus syndromes. Association with anti-Ro (SS-A) antibodies | Q69877518 | ||
| Characterization of a soluble cytoplasmic antigen reactive with sera from patients with systemic lupus erythmatosus | Q70103723 | ||
| Sjöugren's syndrome influence of multiple hla-d region alloantigens on clinical and serologic expression | Q72749846 | ||
| Anti-SSA/Ro and anti-SSB/La autoantibodies bind the surface of apoptotic fetal cardiocytes and promote secretion of TNF-alpha by macrophages | Q73112998 | ||
| Incidence and spectrum of neonatal lupus erythematosus: a prospective study of infants born to mothers with anti-Ro autoantibodies | Q73600793 | ||
| Association of neutropenia in systemic lupus erythematosus (SLE) with anti-Ro and binding of an immunologically cross-reactive neutrophil membrane antigen | Q73664185 | ||
| SSA/Ro antigen expressed on membrane of UVB-induced apoptotic keratinocytes is pathogenic but not detectable in supernatant of cell culture | Q74620671 | ||
| Accessibility of SSA/Ro and SSB/La antigens to maternal autoantibodies in apoptotic human fetal cardiac myocytes | Q77484112 | ||
| Intracellular localisation of the Ro 52kD auto-antigen in HeLa cells visualised with green fluorescent protein chimeras | Q77805761 | ||
| The tripartite motif family identifies cell compartments | Q24291183 | ||
| Autoantigen Ro52 is an E3 ubiquitin ligase | Q24296239 | ||
| Oncogenic protein UnpEL/Usp4 deubiquitinates Ro52 by its isopeptidase activity | Q24297383 | ||
| Developmentally regulated expression of a human "finger"-containing gene encoded by the 5' half of the ret transforming gene | Q24298289 | ||
| Regulation of p27 degradation and S-phase progression by Ro52 RING finger protein | Q24298491 | ||
| UnpEL/Usp4 is ubiquitinated by Ro52 and deubiquitinated by itself | Q24304301 | ||
| The autoantigen Ro52 is an E3 ligase resident in the cytoplasm but enters the nucleus upon cellular exposure to nitric oxide | Q24321488 | ||
| Ro52-mediated monoubiquitination of IKK{beta} down-regulates NF-{kappa}B signalling | Q24324531 | ||
| TRIM family proteins: retroviral restriction and antiviral defence | Q24329175 | ||
| SS-56, a novel cellular target of autoantibody responses in Sjögren syndrome and systemic lupus erythematosus | Q24564914 | ||
| Protein heterogeneity in the human Ro/SSA ribonucleoproteins. The 52- and 60-kD Ro/SSA autoantigens are encoded by separate genes | Q24594978 | ||
| Molecular definition and sequence motifs of the 52-kD component of human SS-A/Ro autoantigen | Q24595305 | ||
| TRIM family proteins and their emerging roles in innate immunity | Q24607229 | ||
| Antibodies mediate intracellular immunity through tripartite motif-containing 21 (TRIM21) | Q24633690 | ||
| Structural differences between the human and mouse 52-kD Ro autoantigens associated with poorly conserved autoantibody activity across species | Q24651055 | ||
| The mapping of the human 52-kD Ro/SSA autoantigen gene to human chromosome 11, and its polymorphisms | Q24671851 | ||
| 52-kD SS-A/Ro: genomic structure and identification of an alternatively spliced transcript encoding a novel leucine zipper-minus autoantigen expressed in fetal and adult heart | Q24678548 | ||
| Structural basis for PRYSPRY-mediated tripartite motif (TRIM) protein function | Q24684586 | ||
| TRIM21 is an IgG receptor that is structurally, thermodynamically, and kinetically conserved | Q27650357 | ||
| Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus | Q28212039 | ||
| The Ro small cytoplasmic ribonucleoproteins: identification of the antigenic protein and its binding site on the Ro RNAs | Q28262911 | ||
| A 1.4-Mb high-resolution physical map and contig of chromosome segment 11p15.5 and genes in the LOH11A metastasis suppressor region | Q28296418 | ||
| The location of a disease-associated polymorphism and genomic structure of the human 52-kDa Ro/SSA locus (SSA1) | Q28299708 | ||
| Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial | Q28304807 | ||
| Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays | Q28646554 | ||
| NF-kappaB: a key role in inflammatory diseases | Q29617726 | ||
| IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors | Q29618425 | ||
| Cellular transcriptional profiling in influenza A virus-infected lung epithelial cells: the role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential contribution to pandemic influenza | Q30331304 | ||
| Downregulation of active IKK beta by Ro52-mediated autophagy | Q30495937 | ||
| Dynamic movements of Ro52 cytoplasmic bodies along microtubules | Q30497238 | ||
| Protein-protein interactions between native Ro52 and immunoglobulin G heavy chain | Q30706449 | ||
| Oxidative stress mediates cell surface expression of SS-A/Ro antigen on keratinocytes | Q33183694 | ||
| Subcellular redistribution and surface exposure of the Ro52, Ro60 and La48 autoantigens during apoptosis in human ductal epithelial cells: a possible mechanism in the pathogenesis of Sjögren's syndrome | Q33185050 | ||
| Sjögren's syndrome: association of anti-Ro(SS-A) antibodies with vasculitis, hematologic abnormalities, and serologic hyperreactivity | Q33479779 | ||
| Tocilizumab in systemic lupus erythematosus: data on safety, preliminary efficacy, and impact on circulating plasma cells from an open-label phase I dosage-escalation study | Q33527462 | ||
| rpt-1, an intracellular protein from helper/inducer T cells that regulates gene expression of interleukin 2 receptor and human immunodeficiency virus type 1 | Q33567423 | ||
| Gene disruption study reveals a nonredundant role for TRIM21/Ro52 in NF-kappaB-dependent cytokine expression in fibroblasts | Q33579495 | ||
| Self protection from anti-viral responses--Ro52 promotes degradation of the transcription factor IRF7 downstream of the viral Toll-Like receptors | Q33644464 | ||
| Cytoplasmic relocation of Daxx induced by Ro52 and FLASH. | Q33653297 | ||
| Pathogenesis of human systemic lupus erythematosus: recent advances | Q33664927 | ||
| The E3 ubiquitin ligase Ro52 negatively regulates IFN-beta production post-pathogen recognition by polyubiquitin-mediated degradation of IRF3 | Q33670447 | ||
| The sequestosome 1/p62 attenuates cytokine gene expression in activated macrophages by inhibiting IFN regulatory factor 8 and TNF receptor-associated factor 6/NF-kappaB activity | Q34118232 | ||
| Dissociation of immune responses to the SS-A (Ro) 52-kd and 60-kd polypeptides in systemic lupus erythematosus and Sjögren's syndrome. | Q45998826 | ||
| A retrospective seven-year analysis of the use of B cell depletion therapy in systemic lupus erythematosus at University College London Hospital: the first fifty patients | Q46067913 | ||
| Clinical significance of anti-Ro52 (TRIM21) antibodies non-associated with anti-SSA 60kDa antibodies: results of a multicentric study | Q46833854 | ||
| SS-A/Ro52, an autoantigen involved in CD28-mediated IL-2 production | Q48024882 | ||
| The Ro52/SS-A autoantigen has elevated expression at the brain microvasculature | Q48176656 | ||
| Cardiac expression of 52beta, an alternative transcript of the congenital heart block-associated 52-kd SS-A/Ro autoantigen, is maximal during fetal development | Q48742268 | ||
| rs660 polymorphism in Ro52 (SSA1; TRIM21) is a marker for age-dependent tolerance induction and efficiency of alloimmunization in sickle cell disease. | Q50619130 | ||
| Anti-Ro antibody and cutaneous vasculitis in systemic lupus erythematosus. | Q51672685 | ||
| Type I interferon-dependent and -independent expression of tripartite motif proteins in immune cells. | Q53497217 | ||
| TRIM21 is a trimeric protein that binds IgG Fc via the B30.2 domain. | Q53587210 | ||
| A novel polymorphism of the SSA1 gene is associated with anti-SS-A/Ro52 autoantibody in Japanese patients with primary Sjögren's syndrome. | Q54649164 | ||
| Increased salivary gland tissue expression of Fas, Fas ligand, cytotoxic T lymphocyte-associated antigen 4, and programmed cell death 1 in primary Sjögren's syndrome. | Q54795286 | ||
| Heterogeneity of RNA protein antigens reactive with sera of patients with systemic lupus erythematosus. Description of a cytoplasmic nonribosomal antigen | Q68342295 | ||
| Estradiol enhances binding to cultured human keratinocytes of antibodies specific for SS-A/Ro and SS-B/La. Another possible mechanism for estradiol influence of lupus erythematosus | Q69036618 | ||
| Correlation of anti-Ro antibody with photosensitivity rash in systemic lupus erythematosus patients | Q69179068 | ||
| Antibodies to cellular antigens in Sjögren's syndrome | Q34478675 | ||
| Ultraviolet light induces binding of antibodies to selected nuclear antigens on cultured human keratinocytes | Q34618445 | ||
| Fas-associated death domain (FADD) and the E3 ubiquitin-protein ligase TRIM21 interact to negatively regulate virus-induced interferon production | Q34675854 | ||
| Expanded double negative T cells in patients with systemic lupus erythematosus produce IL-17 and infiltrate the kidneys | Q34892862 | ||
| Alloimmunization against RBC or PLT antigens is independent of TRIM21 expression in a murine model | Q34960188 | ||
| Vicious circle: systemic autoreactivity in Ro52/TRIM21-deficient mice | Q34994387 | ||
| Autoimmune disease complicating antiviral therapy for hepatitis C virus infection | Q35045126 | ||
| Anti-Ro52 autoantibodies from patients with Sjögren's syndrome inhibit the Ro52 E3 ligase activity by blocking the E3/E2 interface. | Q35378702 | ||
| Efficacy and safety of rituximab in moderately-to-severely active systemic lupus erythematosus: the randomized, double-blind, phase II/III systemic lupus erythematosus evaluation of rituximab trial | Q35993027 | ||
| Overexpression of TRIB2 in human lung cancers contributes to tumorigenesis through downregulation of C/EBPα | Q36055402 | ||
| TRIM/RBCC, a novel class of 'single protein RING finger' E3 ubiquitin ligases | Q36291771 | ||
| A 52-kD protein is a novel component of the SS-A/Ro antigenic particle | Q36354952 | ||
| Ro/SSA autoantibodies directly bind cardiomyocytes, disturb calcium homeostasis, and mediate congenital heart block | Q36402505 | ||
| Systemic lupus erythematosus: all roads lead to type I interferons | Q36608558 | ||
| Enhanced membrane expression of the 52 kDa Ro(SS-A) and La(SS-B) antigens by human keratinocytes induced by TNF alpha | Q36671703 | ||
| Type I interferon in systemic lupus erythematosus. | Q36985415 | ||
| Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23-Th17 pathway | Q37292757 | ||
| The role of IL-23/IL-17 axis in lupus nephritis | Q37397437 | ||
| Cardiac manifestations of neonatal lupus erythematosus: guidelines to management, integrating clues from the bench and bedside | Q37404476 | ||
| Latest update on the Ro/SS-A autoantibody system | Q37459190 | ||
| Rituximab in systemic lupus erythematosus: A systematic review of off-label use in 188 cases | Q37541561 | ||
| Autoimmune response and target autoantigens in Sjogren's syndrome. | Q37772540 | ||
| Autoantibody responses to the "native" 52-kDa SS-A/Ro protein in neonatal lupus syndromes, systemic lupus erythematosus, and Sjogren's syndrome | Q38309839 | ||
| Molecular regulation of B lymphocyte response | Q39647353 | ||
| TRIM21 is essential to sustain IFN regulatory factor 3 activation during antiviral response | Q39876432 | ||
| Ubiquitination of E3 ubiquitin ligase TRIM5 alpha and its potential role | Q40007216 | ||
| Interferon-alpha induces up-regulation and nuclear translocation of the Ro52 autoantigen as detected by a panel of novel Ro52-specific monoclonal antibodies | Q40036932 | ||
| Ro52 functionally interacts with IgG1 and regulates its quality control via the ERAD system. | Q40049469 | ||
| Cutting edge: autoantigen Ro52 is an interferon inducible E3 ligase that ubiquitinates IRF-8 and enhances cytokine expression in macrophages | Q40117899 | ||
| The Sjogren's syndrome-associated autoantigen Ro52 is an E3 ligase that regulates proliferation and cell death | Q40284365 | ||
| Autoantigen Ro52 directly interacts with human IgG heavy chain in vivo in mammalian cells | Q40829522 | ||
| Cutaneous diseases in adults associated with anti-Ro/SS-A autoantibody production | Q41375780 | ||
| Subcellular distribution of Ro ribonucleoprotein complexes and their constituents. | Q41519429 | ||
| Analysis of the intracellular localization and assembly of Ro ribonucleoprotein particles by microinjection into Xenopus laevis oocytes | Q41882450 | ||
| Plasmacytoid dendritic cells (natural interferon- alpha/beta-producing cells) accumulate in cutaneous lupus erythematosus lesions | Q42048367 | ||
| The 52 000 MW Ro/SS-A autoantigen in Sjögren's syndrome/systemic lupus erythematosus (Ro52) is an interferon-gamma inducible tripartite motif protein associated with membrane proximal structures | Q42677729 | ||
| Comment on "Gene disruption study reveals a nonredundant role for TRIM21/Ro52 in NF-kappa B-dependent cytokine expression in fibroblasts". | Q42974567 | ||
| Polymorphisms of the Ro52 gene associated with anti-Ro 52-kd autoantibodies in patients with primary Sjögren's syndrome | Q43550727 | ||
| P275 | copyright license | Creative Commons Attribution 3.0 Unported | Q14947546 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P921 | main subject | systemic lupus erythematosus | Q1485 |
| P304 | page(s) | 718237 | |
| P577 | publication date | 2012-06-04 | |
| P1433 | published in | International journal of rheumatology | Q26853833 |
| P1476 | title | Autoantigen TRIM21/Ro52 as a Possible Target for Treatment of Systemic Lupus Erythematosus | |
| P478 | volume | 2012 |
| Q36376409 | Are Immune Modulating Single Nucleotide Polymorphisms Associated with Necrotizing Enterocolitis? |
| Q89495822 | Autoantibodies reactive to PEP08 are clinically related with morbidity and severity of interstitial lung disease in connective tissue diseases |
| Q90323622 | CIP2A Constrains Th17 Differentiation by Modulating STAT3 Signaling |
| Q90738216 | CSN6-TRIM21 axis instigates cancer stemness during tumorigenesis |
| Q36469094 | Clinical and pathological roles of Ro/SSA autoantibody system. |
| Q38086856 | Cutaneous lupus erythematosus: clinical aspects and molecular pathogenesis. |
| Q37598940 | Cytosolic Fc receptor TRIM21 inhibits seeded tau aggregation. |
| Q93170230 | Diversified Application of Barcoded PLATO (PLATO-BC) Platform for Identification of Protein Interactions |
| Q37713636 | E2/Estrogen receptor/sjogren syndrome-associated autoantigen relieves coactivator activator-induced G1/S arrest to promote breast tumorigenicity |
| Q35133040 | Genome-wide association studies for hematological traits in Chinese Sutai pigs |
| Q30431292 | Mass spectrometric and peptide chip characterization of an assembled epitope: analysis of a polyclonal antibody model serum directed against the Sjøgren/systemic lupus erythematosus autoantigen TRIM21. |
| Q33729528 | Molecular pathway alterations in CD4 T-cells of nonobese diabetic (NOD) mice in the preinsulitis phase of autoimmune diabetes |
| Q97549132 | Negative feedback regulation by HuR controls TRIM21 expression and function in response to UV radiation |
| Q42379044 | Stabilization of phosphofructokinase 1 platelet isoform by AKT promotes tumorigenesis |
| Q39328254 | TRIM dsDNA sensor to restrict innate immune response |
| Q58051874 | Ubiquitin-Proteasome System: Promising Therapeutic Targets in Autoimmune and Neurodegenerative Diseases |
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