scholarly article | Q13442814 |
P819 | ADS bibcode | 2015NatCo...6.8022S |
P356 | DOI | 10.1038/NCOMMS9022 |
P932 | PMC publication ID | 4560765 |
P698 | PubMed publication ID | 26300397 |
P5875 | ResearchGate publication ID | 281309442 |
P2093 | author name string | Wenming Wu | |
Xiaoxia Ren | |||
Jun Fu | |||
Wei Wu | |||
Wei Song | |||
Hong Zhao | |||
Jianming Ying | |||
Linfang Wang | |||
Yefan Zhang | |||
Xiaodong Zhang | |||
Fan Wu | |||
Mengmeng Zhang | |||
Xiaolu Li | |||
Shiying Miao | |||
Jia Yu | |||
Shangze Li | |||
Xin Guan | |||
Wenjie Liu | |||
Fei Miao | |||
Yuechao Zhao | |||
Junbo Liang | |||
Changzheng Liu | |||
Shudong Zong | |||
Yuanyuan Tian | |||
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Overexpression of TGFα in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast | Q67660860 | ||
An essential role for ectodomain shedding in mammalian development | Q77544828 | ||
Hallmarks of Cancer: The Next Generation | Q22252312 | ||
Functional alteration of PARL contributes to mitochondrial dysregulation in Parkinson's disease | Q24294218 | ||
Rhomboid family pseudoproteases use the ER quality control machinery to regulate intercellular signaling | Q24298141 | ||
A novel member of the Rhomboid family, RHBDD1, regulates BIK-mediated apoptosis | Q24309275 | ||
Human rhomboid family-1 gene RHBDF1 participates in GPCR-mediated transactivation of EGFR growth signals in head and neck squamous cancer cells | Q24318727 | ||
Exosome-related multi-pass transmembrane protein TSAP6 is a target of rhomboid protease RHBDD1-induced proteolysis | Q24336330 | ||
EGF signal propagation during C. elegans vulval development mediated by ROM-1 rhomboid | Q24794899 | ||
Site-directed mutagenesis by overlap extension using the polymerase chain reaction | Q27860503 | ||
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008 | Q27860674 | ||
Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans | Q28145545 | ||
Epidermal growth factor-related peptides and their receptors in human malignancies | Q28293442 | ||
Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling | Q28506506 | ||
GC-1 mRHBDD1 knockdown spermatogonia cells lose their spermatogenic capacity in mouse seminiferous tubules | Q28510255 | ||
The epidermal growth factor receptor couples transforming growth factor-alpha, heparin-binding epidermal growth factor-like factor, and amphiregulin to Neu, ErbB-3, and ErbB-4 | Q28513922 | ||
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL | Q29615624 | ||
Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands | Q30443463 | ||
Tumor necrosis factor-alpha converting enzyme (TACE) regulates epidermal growth factor receptor ligand availability | Q30805022 | ||
Fank1 interacts with Jab1 and regulates cell apoptosis via the AP-1 pathway | Q33112702 | ||
Selective roles for tumor necrosis factor alpha-converting enzyme/ADAM17 in the shedding of the epidermal growth factor receptor ligand family: the juxtamembrane stalk determines cleavage efficiency | Q33201079 | ||
A family of rhomboid-like genes: Drosophila rhomboid-1 and roughoid/rhomboid-3 cooperate to activate EGF receptor signaling. | Q33334741 | ||
Estrogen receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer | Q33845160 | ||
Rhomboid and Star facilitate presentation and processing of the Drosophila TGF-alpha homolog Spitz | Q33888173 | ||
Sequence-specific intramembrane proteolysis: identification of a recognition motif in rhomboid substrates | Q34092101 | ||
Intramembrane proteolysis controls diverse signalling pathways throughout evolution | Q34146440 | ||
Mammalian EGF receptor activation by the rhomboid protease RHBDL2 | Q34178493 | ||
Substrate specificity of rhomboid intramembrane proteases is governed by helix-breaking residues in the substrate transmembrane domain | Q34207965 | ||
Human transforming growth factor-alpha: precursor structure and expression in E. coli | Q34245148 | ||
Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE | Q34247194 | ||
iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS | Q34247201 | ||
Expression of the transforming growth factor-alpha/epidermal growth factor receptor pathway in normal human breast epithelial cells | Q34297021 | ||
Intramembrane cleavage of ephrinB3 by the human rhomboid family protease, RHBDL2. | Q34309079 | ||
Intramembrane proteolysis: theme and variations. | Q34342964 | ||
Cross-talk between phospho-STAT3 and PLCγ1 plays a critical role in colorectal tumorigenesis | Q35386200 | ||
Human rhomboid family-1 gene silencing causes apoptosis or autophagy to epithelial cancer cells and inhibits xenograft tumor growth | Q36186343 | ||
Rhomboid proteins: conserved membrane proteases with divergent biological functions | Q36657554 | ||
Epitope tagging of endogenous proteins for genome-wide ChIP-chip studies | Q36731113 | ||
Rhomboid domain containing 2 (RHBDD2): a novel cancer-related gene over-expressed in breast cancer | Q37419573 | ||
Diverse substrate recognition mechanisms for rhomboids; thrombomodulin is cleaved by Mammalian rhomboids | Q39675497 | ||
The drosophila dorsoventral patterning gene gurken produces a dorsally localized RNA and encodes a TGFα-like protein | Q41064456 | ||
Autocrine transforming growth factor-alpha is associated with progression of transformed properties in human colon cancer cells | Q41578950 | ||
Mutation of Glu521 or Glu535 in cytoplasmic loop 5 causes differential misfolding in multiple domains of multidrug and organic anion transporter MRP1 (ABCC1) | Q42085052 | ||
TGF alpha overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas | Q43826975 | ||
Vein is a novel component in the Drosophila epidermal growth factor receptor pathway with similarity to the neuregulins | Q47072513 | ||
The Drosophila spitz gene encodes a putative EGF-like growth factor involved in dorsal-ventral axis formation and neurogenesis | Q48162492 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P407 | language of work or name | English | Q1860 |
P921 | main subject | colorectal cancer | Q188874 |
colorectal carcinoma | Q25493920 | ||
P304 | page(s) | 8022 | |
P577 | publication date | 2015-08-24 | |
P1433 | published in | Nature Communications | Q573880 |
P1476 | title | Rhomboid domain containing 1 promotes colorectal cancer growth through activation of the EGFR signalling pathway | |
P478 | volume | 6 |