Rhomboid domain containing 1 promotes colorectal cancer growth through activation of the EGFR signalling pathway

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Rhomboid domain containing 1 promotes colorectal cancer growth through activation of the EGFR signalling pathway is …
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scholarly articleQ13442814

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P819ADS bibcode2015NatCo...6.8022S
P356DOI10.1038/NCOMMS9022
P932PMC publication ID4560765
P698PubMed publication ID26300397
P5875ResearchGate publication ID281309442

P2093author name stringWenming Wu
Xiaoxia Ren
Jun Fu
Wei Wu
Wei Song
Hong Zhao
Jianming Ying
Linfang Wang
Yefan Zhang
Xiaodong Zhang
Fan Wu
Mengmeng Zhang
Xiaolu Li
Shiying Miao
Jia Yu
Shangze Li
Xin Guan
Wenjie Liu
Fei Miao
Yuechao Zhao
Junbo Liang
Changzheng Liu
Shudong Zong
Yuanyuan Tian
P2860cites workProduction and auto-induction of transforming growth factor-α in human keratinocytesQ59048981
Overexpression of TGFα in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breastQ67660860
An essential role for ectodomain shedding in mammalian developmentQ77544828
Hallmarks of Cancer: The Next GenerationQ22252312
Functional alteration of PARL contributes to mitochondrial dysregulation in Parkinson's diseaseQ24294218
Rhomboid family pseudoproteases use the ER quality control machinery to regulate intercellular signalingQ24298141
A novel member of the Rhomboid family, RHBDD1, regulates BIK-mediated apoptosisQ24309275
Human rhomboid family-1 gene RHBDF1 participates in GPCR-mediated transactivation of EGFR growth signals in head and neck squamous cancer cellsQ24318727
Exosome-related multi-pass transmembrane protein TSAP6 is a target of rhomboid protease RHBDD1-induced proteolysisQ24336330
EGF signal propagation during C. elegans vulval development mediated by ROM-1 rhomboidQ24794899
Site-directed mutagenesis by overlap extension using the polymerase chain reactionQ27860503
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008Q27860674
Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humansQ28145545
Epidermal growth factor-related peptides and their receptors in human malignanciesQ28293442
Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodelingQ28506506
GC-1 mRHBDD1 knockdown spermatogonia cells lose their spermatogenic capacity in mouse seminiferous tubulesQ28510255
The epidermal growth factor receptor couples transforming growth factor-alpha, heparin-binding epidermal growth factor-like factor, and amphiregulin to Neu, ErbB-3, and ErbB-4Q28513922
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARLQ29615624
Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligandsQ30443463
Tumor necrosis factor-alpha converting enzyme (TACE) regulates epidermal growth factor receptor ligand availabilityQ30805022
Fank1 interacts with Jab1 and regulates cell apoptosis via the AP-1 pathwayQ33112702
Selective roles for tumor necrosis factor alpha-converting enzyme/ADAM17 in the shedding of the epidermal growth factor receptor ligand family: the juxtamembrane stalk determines cleavage efficiencyQ33201079
A family of rhomboid-like genes: Drosophila rhomboid-1 and roughoid/rhomboid-3 cooperate to activate EGF receptor signaling.Q33334741
Estrogen receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancerQ33845160
Rhomboid and Star facilitate presentation and processing of the Drosophila TGF-alpha homolog SpitzQ33888173
Sequence-specific intramembrane proteolysis: identification of a recognition motif in rhomboid substratesQ34092101
Intramembrane proteolysis controls diverse signalling pathways throughout evolutionQ34146440
Mammalian EGF receptor activation by the rhomboid protease RHBDL2Q34178493
Substrate specificity of rhomboid intramembrane proteases is governed by helix-breaking residues in the substrate transmembrane domainQ34207965
Human transforming growth factor-alpha: precursor structure and expression in E. coliQ34245148
Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACEQ34247194
iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPSQ34247201
Expression of the transforming growth factor-alpha/epidermal growth factor receptor pathway in normal human breast epithelial cellsQ34297021
Intramembrane cleavage of ephrinB3 by the human rhomboid family protease, RHBDL2.Q34309079
Intramembrane proteolysis: theme and variations.Q34342964
Cross-talk between phospho-STAT3 and PLCγ1 plays a critical role in colorectal tumorigenesisQ35386200
Human rhomboid family-1 gene silencing causes apoptosis or autophagy to epithelial cancer cells and inhibits xenograft tumor growthQ36186343
Rhomboid proteins: conserved membrane proteases with divergent biological functionsQ36657554
Epitope tagging of endogenous proteins for genome-wide ChIP-chip studiesQ36731113
Rhomboid domain containing 2 (RHBDD2): a novel cancer-related gene over-expressed in breast cancerQ37419573
Diverse substrate recognition mechanisms for rhomboids; thrombomodulin is cleaved by Mammalian rhomboidsQ39675497
The drosophila dorsoventral patterning gene gurken produces a dorsally localized RNA and encodes a TGFα-like proteinQ41064456
Autocrine transforming growth factor-alpha is associated with progression of transformed properties in human colon cancer cellsQ41578950
Mutation of Glu521 or Glu535 in cytoplasmic loop 5 causes differential misfolding in multiple domains of multidrug and organic anion transporter MRP1 (ABCC1)Q42085052
TGF alpha overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreasQ43826975
Vein is a novel component in the Drosophila epidermal growth factor receptor pathway with similarity to the neuregulinsQ47072513
The Drosophila spitz gene encodes a putative EGF-like growth factor involved in dorsal-ventral axis formation and neurogenesisQ48162492
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectcolorectal cancerQ188874
colorectal carcinomaQ25493920
P304page(s)8022
P577publication date2015-08-24
P1433published inNature CommunicationsQ573880
P1476titleRhomboid domain containing 1 promotes colorectal cancer growth through activation of the EGFR signalling pathway
P478volume6