Transcriptional repression of Mad-Max complex by human umbilical cord blood stem cells downregulates extracellular signal-regulated kinase in glioblastoma

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Transcriptional repression of Mad-Max complex by human umbilical cord blood stem cells downregulates extracellular signal-regulated kinase in glioblastoma is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1089/SCD.2011.0424
P932PMC publication ID3376458
P698PubMed publication ID21933022

P50authorJasti S. RaoQ108443825
P2093author name stringKiran Kumar Velpula
Dzung H Dinh
Venkata Ramesh Dasari
Andrew J Tsung
P2860cites workInteraction of alpha9beta1 integrin with thrombospondin-1 promotes angiogenesisQ24301960
Mad: a heterodimeric partner for Max that antagonizes Myc transcriptional activityQ24320236
The essential cofactor TRRAP recruits the histone acetyltransferase hGCN5 to c-MycQ24554343
The cytoplasmic domain of the integrin alpha9 subunit requires the adaptor protein paxillin to inhibit cell spreading but promotes cell migration in a paxillin-independent mannerQ24555127
Signaling through focal adhesion kinaseQ28198051
Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation eventsQ28609216
How MAP kinases are regulatedQ28609360
Required role of focal adhesion kinase (FAK) for integrin-stimulated cell migrationQ30175391
Complex formation with focal adhesion kinase: A mechanism to regulate activity and subcellular localization of Src kinasesQ30454300
Erk1 and Erk2 regulate endothelial cell proliferation and migration during mouse embryonic angiogenesisQ33518538
Regulation of glioblastoma progression by cord blood stem cells is mediated by downregulation of cyclin D1.Q33859439
The Max network gone mad.Q33967079
Thermodynamics of protein-protein interactions of cMyc, Max, and Mad: effect of polyions on protein dimerization.Q34041505
MEK/ERK inhibitor U0126 increases the radiosensitivity of rhabdomyosarcoma cells in vitro and in vivo by downregulating growth and DNA repair signalsQ34721752
Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesionQ35107957
Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention.Q35166852
JAK/STAT, Raf/MEK/ERK, PI3K/Akt and BCR-ABL in cell cycle progression and leukemogenesisQ35635353
MMP-9 short interfering RNA induced senescence resulting in inhibition of medulloblastoma growth via p16(INK4a) and mitogen-activated protein kinase pathwayQ35867473
Drosophila Myc is oncogenic in mammalian cells and plays a role in the diminutive phenotypeQ35993087
Oncogenes as molecular targets in lymphomaQ36085363
Transcriptional regulation and transformation by Myc proteinsQ36215755
Differential modulation of cyclin gene expression by MYCQ36258572
Sensing invasion: cell surface receptors driving spreading of glioblastoma.Q37581541
Transcriptional activation of cyclin D1 promoter by FAK contributes to cell cycle progressionQ39250653
Contribution of reactive oxygen species to migration/invasion of human glioblastoma cells U87 via ERK-dependent COX-2/PGE(2) activationQ39791378
MEK/ERK inhibitor U0126 affects in vitro and in vivo growth of embryonal rhabdomyosarcoma.Q39877577
Regulatory effect of nerve growth factor in alpha9beta1 integrin-dependent progression of glioblastoma.Q39905965
Targeting the RAF/MEK/ERK, PI3K/AKT and p53 pathways in hematopoietic drug resistance.Q40154931
Down-regulation of c-Myc following MEK/ERK inhibition halts the expression of malignant phenotype in rhabdomyosarcoma and in non muscle-derived human tumors.Q40245452
MEK1 and MEK2, different regulators of the G1/S transition.Q40530177
Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entryQ40976467
Myc induces cyclin D1 expression in the absence of de novo protein synthesis and links mitogen-stimulated signal transduction to the cell cycle.Q41426806
Effects of the MYC oncogene antagonist, MAD, on proliferation, cell cycling and the malignant phenotype of human brain tumour cellsQ44102597
PKCalpha-mediated ERK, JNK and p38 activation regulates the myogenic program in human rhabdomyosarcoma cells.Q44108504
The MAP kinase pathway is required for entry into mitosis and cell survival.Q44737512
Phase I trial of adenovirus-mediated p53 gene therapy for recurrent glioma: biological and clinical resultsQ45863348
Glial cell-derived neurotrophic factor increases migration of human chondrosarcoma cells via ERK and NF-kappaB pathways.Q46033846
Kinetics of myc-max-mad gene expression during hepatocyte proliferation in vivo: Differential regulation of mad family and stress-mediated induction of c-myc.Q47234107
Integrins and GTPases in tumour cell growth, motility and invasionQ47721551
MMP2 role in breast cancer brain metastasis development and its regulation by TIMP2 and ERK1/2.Q48166289
Elasticity of the human red blood cell skeletonQ56894640
Infiltration of blood outgrowth endothelial cells into tumor spheroids: role of matrix metalloproteinases and irradiationQ57384578
Ets-1 and integrin beta3 for lung metastasis from colorectal cancerQ74332033
Synergistic effects of epidermal growth factor and hepatocyte growth factor on human ovarian cancer cell invasion and migration: role of extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinaseQ80731014
P433issue10
P921main subjectglioblastomaQ282142
P304page(s)1779-1793
P577publication date2011-11-21
P1433published inStem Cells and DevelopmentQ15724421
P1476titleTranscriptional repression of Mad-Max complex by human umbilical cord blood stem cells downregulates extracellular signal-regulated kinase in glioblastoma
P478volume21

Reverse relations

cites work (P2860)
Q41253971Cord blood stem cells revert glioma stem cell EMT by down regulating transcriptional activation of Sox2 and Twist1.
Q36310662EGFR and c-Met Cross Talk in Glioblastoma and Its Regulation by Human Cord Blood Stem Cells
Q93155087GLUT1 and TUBB4 in Glioblastoma Could be Efficacious Targets
Q37193406Insulin receptor phosphorylation by endogenous insulin or the insulin analog AspB10 promotes mammary tumor growth independent of the IGF-I receptor
Q36390914Mxi1-0 regulates the growth of human umbilical vein endothelial cells through extracellular signal-regulated kinase 1/2 (ERK1/2) and interleukin-8 (IL-8)-dependent pathways
Q36629426Radiation-induced hypomethylation triggers urokinase plasminogen activator transcription in meningioma cells

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