Emerging drugs for the treatment of ulcerative colitis

scientific article

Emerging drugs for the treatment of ulcerative colitis is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1517/14728210903146882
P932PMC publication ID4563345
P698PubMed publication ID19656075
P5875ResearchGate publication ID26718268

P2093author name stringFabio Cominelli
Theresa T Pizarro
Luca Pastorelli
Maurizio Vecchi
P2860cites workNatalizumab Induction and Maintenance Therapy for Crohn's DiseaseQ22250890
Probiotics for induction of remission in ulcerative colitisQ24242963
Azathioprine and 6-mercaptopurine for maintenance of remission in ulcerative colitisQ24243219
Oral 5-aminosalicylic acid for maintenance of remission in ulcerative colitisQ24246085
PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDLQ24311741
Reduced Paneth cell alpha-defensins in ileal Crohn's diseaseQ24538724
The risk of colorectal cancer in ulcerative colitis: a meta-analysisQ24669747
Increased risk of lymphoma among inflammatory bowel disease patients treated with azathioprine and 6-mercaptopurineQ24685403
Retarded release phosphatidylcholine benefits patients with chronic active ulcerative colitisQ24685584
Trichuris suis therapy in Crohn's diseaseQ24685735
Maintaining remission of ulcerative colitis with the probiotic Escherichia coli Nissle 1917 is as effective as with standard mesalazineQ24685766
A pilot trial of Saccharomyces boulardii in ulcerative colitisQ28184581
Trichuris suis therapy for active ulcerative colitis: a randomized controlled trialQ28244734
Progressive multifocal leukoencephalopathy after natalizumab therapy for Crohn's diseaseQ28255557
Cell-based drug deliveryQ28257039
Infliximab for induction and maintenance therapy for ulcerative colitisQ28285876
A new mesalazine gel enema in the treatment of left-sided ulcerative colitis: a randomized controlled multicentre trialQ57012796
Erythrocytes-Mediated Delivery of Dexamethasone in Steroid-Dependent IBD Patients-A Pilot Uncontrolled StudyQ58193662
Risk factors for colorectal cancer in patients with ulcerative colitis: A case-control studyQ58834128
Epithelial NEMO links innate immunity to chronic intestinal inflammationQ59091394
VSL#3 Probiotic-Mixture Induces Remission in Patients with Active Ulcerative ColitisQ59120549
Increased intestinal permeability and NOD2 variants in familial and sporadic Crohn's diseaseQ62572598
Course of ulcerative colitis: analysis of changes in disease activity over yearsQ72036054
Double-blind comparison of an oral Escherichia coli preparation and mesalazine in maintaining remission of ulcerative colitisQ73837821
The natural history of corticosteroid therapy for inflammatory bowel disease: a population-based studyQ74315857
Erythrocyte engineering for drug delivery and targetingQ74845391
A pilot study of treatment of active ulcerative colitis with natalizumab, a humanized monoclonal antibody to alpha-4 integrinQ77868324
Inhibition of Smad7 with a specific antisense oligonucleotide facilitates TGF-beta1-mediated suppression of colitisQ79333602
Effect of once- or twice-daily MMX mesalamine (SPD476) for the induction of remission of mild to moderately active ulcerative colitisQ79596195
Once-daily, high-concentration MMX mesalamine in active ulcerative colitisQ79621238
Rosiglitazone, a PPARgamma ligand, modulates signal transduction pathways during the development of acute TNBS-induced colitis in ratsQ79895160
Nonadherence in inflammatory bowel disease: results of factor analysisQ80407754
Natalizumab: AN 100226, anti-4alpha integrin monoclonal antibodyQ80417031
Phosphatidylcholine and lysophosphatidylcholine in intestinal mucus of ulcerative colitis patients. A quantitative approach by nanoElectrospray-tandem mass spectrometryQ80928564
Risk factors for non-adherence to medication in inflammatory bowel disease patientsQ81468420
Phosphatidylcholine for steroid-refractory chronic ulcerative colitis: a randomized trialQ81535344
Helminths as governors of immune-mediated inflammationQ28289350
Rosiglitazone for active ulcerative colitis: a randomized placebo-controlled trialQ30440147
Impact on the composition of the faecal flora by a new probiotic preparation: preliminary data on maintenance treatment of patients with ulcerative colitis.Q30581062
Non-pathogenic Escherichia coli versus mesalazine for the treatment of ulcerative colitis: a randomised trialQ33872486
Cyclosporine in severe ulcerative colitis refractory to steroid therapyQ34060783
Adalimumab induction therapy for ulcerative colitis with intolerance or lost response to infliximab: an open-label studyQ34100121
PPAR gamma: an essential role in metabolic controlQ34267993
CTLA4Ig: a novel inhibitor of costimulationQ34330606
Low dose steroids and clinical relapse in Crohn's disease: a controlled trialQ34474565
A phase I trial with transgenic bacteria expressing interleukin-10 in Crohn's diseaseQ34529230
Golimumab, a human antibody to tumour necrosis factor {alpha} given by monthly subcutaneous injections, in active rheumatoid arthritis despite methotrexate therapy: the GO-FORWARD StudyQ34601527
Long-term risk of cardiovascular events with rosiglitazone: a meta-analysisQ34686103
A new orally bioavailable synthetic androstene inhibits collagen-induced arthritis in the mouse: androstene hormones as regulators of regulatory T cellsQ34697252
Review article: diagnosis, monitoring and treatment of distal colitisQ35144997
Double blind, placebo controlled trial of the remission inducing and steroid sparing properties of an ICAM-1 antisense oligodeoxynucleotide, alicaforsen (ISIS 2302), in active steroid dependent Crohn's diseaseQ35594747
A randomised, controlled, double blind, escalating dose study of alicaforsen enema in active ulcerative colitisQ35596970
PPARgamma as a new therapeutic target in inflammatory bowel diseasesQ35768913
Mesalamine derivatives in the treatment of Crohn's diseaseQ35792320
How effective are the usual treatments for ulcerative colitis?Q35826343
Intravenous cyclosporine for the treatment of severe steroid refractory ulcerative colitis: what is the cost?Q36188830
Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gammaQ36403491
American Gastroenterological Association Institute technical review on corticosteroids, immunomodulators, and infliximab in inflammatory bowel diseaseQ36418617
Open label trial of granulocyte apheresis suggests therapeutic efficacy in chronically active steroid refractory ulcerative colitisQ36474506
TNFalpha blockade in human diseases: an overview of efficacy and safetyQ36536861
Review article: thiopurines in inflammatory bowel diseaseQ36570796
Probiotics in experimental and human inflammatory bowel disease: discussion pointsQ36720509
Lymphoma risk in inflammatory bowel disease: is it the disease or its treatment?Q36864836
Heparin, low molecular weight heparin, and derivatives in thrombosis, angiogenesis, and inflammation: emerging linksQ36880833
Randomised trial of once- or twice-daily MMX mesalazine for maintenance of remission in ulcerative colitisQ36930800
Quality of life of patients with ulcerative colitis: past, present, and futureQ36987080
Role of the intestinal barrier in inflammatory bowel diseaseQ37058869
A clinical trial of combined use of rosiglitazone and 5-aminosalicylate for ulcerative colitisQ37169674
Mechanisms of probiotic action: Implications for therapeutic applications in inflammatory bowel diseasesQ37214848
Molecular analysis of the intestinal microflora in IBD.Q37349762
TGF-beta1 and Smad7 in the regulation of IBD.Q37349788
The 6-month safety and efficacy of abatacept in patients with rheumatoid arthritis who underwent a washout after anti-tumour necrosis factor therapy or were directly switched to abatacept: the ARRIVE trialQ37374964
Clinical efficacy and safety of abatacept in methotrexate-naive patients with early rheumatoid arthritis and poor prognostic factorsQ37404890
Pathogenesis of and unifying hypothesis for idiopathic pouchitisQ37405919
Erythrocyte-mediated delivery of dexamethasone in patients with mild-to-moderate ulcerative colitis, refractory to mesalamine: a randomized, controlled study.Q39315460
NF-kappaB- and AP-1-mediated induction of human beta defensin-2 in intestinal epithelial cells by Escherichia coli Nissle 1917: a novel effect of a probiotic bacterium.Q40017434
The intestinal anti-inflammatory activity of UR-12746S on reactivated experimental colitis is mediated through downregulation of cytokine production.Q40608087
Colorectal cancer prevention in ulcerative colitis: a case-control study.Q41716716
PPARgamma in monocytes: less pain, any gain?Q41755827
Rosiglitazone, an agonist of peroxisome proliferator-activated receptor gamma, reduces chronic colonic inflammation in rats.Q42477845
A randomized, double-blind, sham-controlled study of granulocyte/monocyte apheresis for active ulcerative colitisQ42661339
Basiliximab for the treatment of steroid-resistant ulcerative colitis: further experience in moderate and severe diseaseQ42684792
Gastrointestinal transit, release and plasma pharmacokinetics of a new oral budesonide formulationQ42758588
Risk for colorectal cancer in ulcerative colitis: changes, causes and management strategiesQ43072226
Randomized controlled trial of the effect of bifidobacteria-fermented milk on ulcerative colitisQ43867015
Ulcerative colitis: patient characteristics may predict 10-yr disease recurrence in a European-wide population-based cohortQ44024340
Adalimumab induction therapy for Crohn disease previously treated with infliximab: a randomized trialQ44151825
Gastrointestinal transit and 5-ASA release from a new mesalazine extended-release formulation.Q44299613
Multicenter randomized controlled trial for the treatment of ulcerative colitis with a leukocytapheresis columnQ44304714
The effect of 5-aminosalicylic acid-containing drugs on sulfide production by sulfate-reducing and amino acid-fermenting bacteriaQ44375240
Intravenous hydrocortisone premedication reduces antibodies to infliximab in Crohn's disease: a randomized controlled trialQ44387824
The use of thiopurines for the treatment of inflammatory bowel diseases in clinical practice.Q44408412
Oral beclometasone dipropionate in the treatment of extensive and left-sided active ulcerative colitis: a multicentre randomised study.Q44488900
Epidermal growth factor enemas with oral mesalamine for mild-to-moderate left-sided ulcerative colitis or proctitisQ44524238
Long-term results of low-dose intravenous ciclosporin for acute severe ulcerative colitisQ44535154
Long-term therapy with sulphasalazine protects against colorectal cancer in ulcerative colitis: a retrospective study of colorectal cancer risk and compliance with treatment in Leicestershire.Q44758742
A phase I study of visilizumab, a humanized anti-CD3 monoclonal antibody, in severe steroid-refractory ulcerative colitisQ44833501
Adsorptive granulocyte and monocyte apheresis versus prednisolone in patients with corticosteroid-dependent moderately severe ulcerative colitisQ45009367
Effect of a probiotic preparation (VSL#3) on induction and maintenance of remission in children with ulcerative colitisQ46143449
Topical treatment of distal active ulcerative colitis with beclomethasone dipropionate or mesalamine: a single-blind randomized controlled trialQ46368289
A new oral delivery system for 5-ASA: preliminary clinical findings for MMx.Q46469247
Infliximab as rescue therapy in severe to moderately severe ulcerative colitis: a randomized, placebo-controlled study.Q46531976
Treatment of ulcerative colitis with a humanized antibody to the alpha4beta7 integrinQ46549276
Efficacy of intracolonic administration of low-molecular-weight heparin CB-01-05, compared to other low-molecular-weight heparins and unfractionated heparin, in experimentally induced colitis in rat.Q46605939
TARGIT technology: coated starch capsules for site-specific drug delivery into the lower gastrointestinal tractQ46810701
Oral, colonic-release low-molecular-weight heparin: an initial open study of Parnaparin-MMX for the treatment of mild-to-moderate left-sided ulcerative colitis.Q47220932
Work losses related to inflammatory bowel disease in the United States: results from the National Health Interview Survey.Q47827799
Probiotic preparation VSL#3 induces remission in children with mild to moderate acute ulcerative colitis: a pilot studyQ48677169
Treatment of murine colitis by Lactococcus lactis secreting interleukin-10.Q49073992
Basiliximab (anti-CD25) in combination with steroids may be an effective new treatment for steroid-resistant ulcerative colitis.Q50483095
Leukocytapheresis in ulcerative colitis: results of a multicenter double-blind prospective case-control study with sham apheresis as placebo treatment.Q51447024
Efficacy of adalimumab for the management of inflammatory bowel disease in the clinical setting.Q51818669
Long-term outcome of adalimumab therapy for ulcerative colitis with intolerance or lost response to infliximab: a single-centre experience.Q51872306
Visilizumab induces apoptosis of mucosal T lymphocytes in ulcerative colitis through activation of caspase 3 and 8 dependent pathways.Q53482470
Clinical, biological, and endoscopic picture of attacks of Crohn's disease. Evolution on prednisolone. Groupe d'Etude Thérapeutique des Affections Inflammatoires Digestives.Q54327204
Probiotic E. coli treatment mediates antimicrobial human beta-defensin synthesis and fecal excretion in humans.Q54411332
Peroxisome proliferator-activated receptor gamma is induced during differentiation of colon epithelium cells.Q54776568
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectulcerative colitisQ1477
P304page(s)505-521
P577publication date2009-09-01
P1433published inExpert Opinion on Emerging DrugsQ5421207
P1476titleEmerging drugs for the treatment of ulcerative colitis
P478volume14