Tumor cell programmed death ligand 1-mediated T cell suppression is overcome by coexpression of CD80

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Tumor cell programmed death ligand 1-mediated T cell suppression is overcome by coexpression of CD80 is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4049/JIMMUNOL.1003682
P932PMC publication ID3377446
P698PubMed publication ID21555531
P5875ResearchGate publication ID51110731

P50authorBruce R KsanderQ87852809
P2093author name stringSuzanne Ostrand-Rosenberg
Minu K Srivastava
Samuel T Haile
Jacobus J Bosch
Sabine Britting
Annette M Zeender
Julie B Wolf
Nnenna I Agu
Preethi Somasundaram
P2860cites workBlockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine productionQ24292957
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CD80 cytoplasmic domain controls localization of CD28, CTLA-4, and protein kinase Ctheta in the immunological synapseQ30478206
The M1 form of tumor-associated macrophages in non-small cell lung cancer is positively associated with survival timeQ33546133
Cell-based vaccines for the stimulation of immunity to metastatic cancersQ33776134
Poly-ICLC promotes the infiltration of effector T cells into intracranial gliomas via induction of CXCL10 in IFN-alpha and IFN-gamma dependent mannersQ33945653
Selective expansion of chimeric antigen receptor-targeted T-cells with potent effector function using interleukin-4.Q34055865
B7-H1/CD80 interaction is required for the induction and maintenance of peripheral T-cell toleranceQ34122678
Interferon regulatory factor-1 is prerequisite to the constitutive expression and IFN-gamma-induced upregulation of B7-H1 (CD274).Q34484749
Blockade of B7-H1 and PD-1 by monoclonal antibodies potentiates cancer therapeutic immunityQ34554995
Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responsesQ34650346
Interaction of human PD-L1 and B7-1.Q34789854
Co-inhibitory molecules of the B7-CD28 family in the control of T-cell immunityQ35762422
Regulatory T cells, tumour immunity and immunotherapyQ36430144
B7-H1 is a ubiquitous antiapoptotic receptor on cancer cellsQ36508914
Activation and differentiation requirements of primary T cells in vitroQ36566049
Locus-specific analysis of human leukocyte antigen class I expression in melanoma cell linesQ36922798
PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cellsQ36986702
PDL-1 upregulation on monocytes and T cells by HIV via type I interferon: restricted expression of type I interferon receptor by CCR5-expressing leukocytesQ37408390
Uveal melanoma cell-based vaccines express MHC II molecules that traffic via the endocytic and secretory pathways and activate CD8+ cytotoxic, tumor-specific T cells.Q39832869
The absence of invariant chain in MHC II cancer vaccines enhances the activation of tumor-reactive type 1 CD4+ T lymphocytes.Q40088629
MHC class II-transduced tumor cells originating in the immune-privileged eye prime and boost CD4(+) T lymphocytes that cross-react with primary and metastatic uveal melanoma cellsQ40136451
B7-H1 blockade augments adoptive T-cell immunotherapy for squamous cell carcinomaQ40626031
Subcellular localization of CD80 receptors is dependent on an intact cytoplasmic tail and is required for CD28-dependent T cell costimulation.Q41158763
Generation of activated killer (AK) cells by recombinant interleukin 2 (rIL 2) in collaboration with interferon-gamma (IFN-gamma).Q41360601
Characterization of a highly invasive and spontaneously metastatic human malignant melanoma cell lineQ41699259
Lung cancer patients' CD4(+) T cells are activated in vitro by MHC II cell-based vaccines despite the presence of myeloid-derived suppressor cellsQ42114592
Upregulation of PD-L1 on monocytes and dendritic cells by HIV-1 derived TLR ligandsQ42932292
A phase I trial of adoptive transfer of allogeneic natural killer cells in patients with advanced non-small cell lung cancerQ42940016
CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86.Q45092706
Essential role of dendritic cell CD80/CD86 costimulation in the induction, but not reactivation, of TH2 effector responses in a mouse model of asthmaQ47229710
Activation of tumor-specific CD4(+) T lymphocytes by major histocompatibility complex class II tumor cell vaccines: a novel cell-based immunotherapy.Q48009892
Generation of an optimized polyvalent monocyte-derived dendritic cell vaccine by transfecting defined RNAs after rather than before maturation.Q50777089
B7-H1 up-regulation on dendritic-like leukemia cells suppresses T cell immune function through modulation of IL-10/IL-12 production and generation of Treg cells.Q51808283
Growth of cell lines and clinical specimens of human non-small cell lung cancer in a serum-free defined medium.Q52826622
A novel phenotype for an activated macrophage: the type 2 activated macrophage.Q52940996
The MCF10 family of spontaneously immortalized human breast epithelial cell lines: models of neoplastic progression.Q53477584
IFN-gamma modulates the early development of Th1 and Th2 responses in a murine model of cutaneous leishmaniasisQ54285337
PD-L1 expression on human ocular cells and its possible role in regulating immune-mediated ocular inflammation.Q54515974
Blockade of PD-L1 (B7-H1) augments human tumor-specific T cell responses in vitroQ56902028
Studies using antigen-presenting cells lacking expression of both B7-1 (CD80) and B7-2 (CD86) show distinct requirements for B7 molecules during priming versus restimulation of Th2 but not Th1 cytokine productionQ56907534
Human B7-1 (CD80) and B7-2 (CD86) bind with similar avidities but distinct kinetics to CD28 and CTLA-4 receptorsQ56909582
Transmembrane signaling through CD80 (B7-1) induces growth arrest and cell spreading of human B lymphocytes accompanied by protein tyrosine phosphorylationQ71503485
Signal transduction by B7/BB1 expressed on activated T lymphocytes: cross-linking of B7/BB1 induces protein tyrosine phosphorylation and synergizes with signalling through T-cell receptor/CD3Q71565255
Melanomas that develop within the eye inhibit lymphocyte proliferationQ73923165
Two regions in the CD80 cytoplasmic tail regulate CD80 redistribution and T cell costimulationQ77319204
Tumor cells transduced with the MHC class II Transactivator and CD80 activate tumor-specific CD4+ T cells whether or not they are silenced for invariant chainQ82310347
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)6822-6829
P577publication date2011-05-09
P1433published inJournal of ImmunologyQ3521441
P1476titleTumor cell programmed death ligand 1-mediated T cell suppression is overcome by coexpression of CD80
P478volume186

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