Association of DNA methylation in the brain with age in older persons is confounded by common neuropathologies

scientific article

Association of DNA methylation in the brain with age in older persons is confounded by common neuropathologies is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.BIOCEL.2015.05.009
P932PMC publication ID4564337
P698PubMed publication ID26003740
P5875ResearchGate publication ID277133617

P50authorAlexander MeissnerQ74886189
Philip L. De JagerQ87721560
Lori B ChibnikQ91244792
Sue LeurgansQ60697378
David A BennettQ66739430
Julie A. SchneiderQ67212579
P2093author name stringLei Yu
Jingyun Yang
Gyan P Srivastava
Christopher Gaiteri
P2860cites workDNA methylation patterns and epigenetic memoryQ22065780
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signalsQ22122053
Distinct DNA methylation changes highly correlated with chronological age in the human brainQ24616264
Epigenomic profiling reveals DNA-methylation changes associated with major psychosisQ24655403
ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathologyQ29417099
The history of cancer epigeneticsQ29617273
DNA methylation: past, present and future directionsQ31530974
Reduced MeCP2 expression is frequent in autism frontal cortex and correlates with aberrant MECP2 promoter methylationQ33283941
DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neuronsQ33299459
Age-specific epigenetic drift in late-onset Alzheimer's diseaseQ33351991
The neuropathology of probable Alzheimer disease and mild cognitive impairmentQ33616561
Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscapeQ33742677
A DNA methylation fingerprint of 1628 human samplesQ34187360
Epigenetic changes in Alzheimer's disease: decrements in DNA methylationQ34233161
Common DNA methylation alterations in multiple brain regions in autism.Q34287640
Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other lociQ34433829
Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's diseaseQ34433837
Life-span cognitive activity, neuropathologic burden, and cognitive agingQ34653857
Inter-individual variability contrasts with regional homogeneity in the human brain DNA methylomeQ35097941
Impact of aging on DNA methylationQ35119503
Association of Brain DNA methylation in SORL1, ABCA7, HLA-DRB5, SLC24A4, and BIN1 with pathological diagnosis of Alzheimer diseaseQ35130600
Differential DNA methylation profiles of coding and non-coding genes define hippocampal sclerosis in human temporal lobe epilepsy.Q35533933
DNA methylation signatures in development and aging of the human prefrontal cortexQ35748368
DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patientsQ35874941
Overview and findings from the religious orders studyQ36130996
Epigenetic modifications in frontal cortex from Alzheimer's disease and bipolar disorder patientsQ36136017
Overview and findings from the rush Memory and Aging ProjectQ36226167
Cognitive impairment, decline and fluctuations in older community-dwelling subjects with Lewy bodiesQ36315342
Relation of neuropathology to cognition in persons without cognitive impairmentQ36374970
Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarrayQ36670000
A cell epigenotype specific model for the correction of brain cellular heterogeneity bias and its application to age, brain region and major depressionQ36891918
Ischemic heart disease and stroke in relation to blood DNA methylationQ36949767
Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island contextQ37283233
Charting a dynamic DNA methylation landscape of the human genomeQ37292011
Much of late life cognitive decline is not due to common neurodegenerative pathologies.Q37354720
Genetic susceptibility for ischemic infarction and arteriolosclerosis based on neuropathologic evaluationsQ37411842
Characterization of the DNA methylome and its interindividual variation in human peripheral blood monocytesQ37417130
Disentangling the effects of age and APOE on neuropathology and late life cognitive declineQ37438618
Distinctive patterns of DNA methylation associated with Parkinson disease: identification of concordant epigenetic changes in brain and peripheral blood leukocytesQ37478171
Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapiesQ37615626
Consistent decrease in global DNA methylation and hydroxymethylation in the hippocampus of Alzheimer's disease patients.Q37638856
Neurofibrillary tangles mediate the association of amyloid load with clinical Alzheimer disease and level of cognitive functionQ47945508
Education modifies the association of amyloid but not tangles with cognitive functionQ48766555
Neocortical cell counts in normal human adult agingQ69111257
P921main subjectDNA methylationQ874745
P304page(s)58-64
P577publication date2015-05-21
P1433published inInternational Journal of Biochemistry & Cell BiologyQ6051320
P1476titleAssociation of DNA methylation in the brain with age in older persons is confounded by common neuropathologies
P478volume67

Reverse relations

cites work (P2860)
Q38438118A genome-wide profiling of brain DNA hydroxymethylation in Alzheimer's disease.
Q58798030A multi-omic atlas of the human frontal cortex for aging and Alzheimer's disease research
Q51739639APOE DNA methylation is altered in Lewy body dementia.
Q47398412Association Between Brain Gene Expression, DNA Methylation, and Alteration of Ex Vivo Magnetic Resonance Imaging Transverse Relaxation in Late-Life Cognitive Decline
Q64325257Cell-specific histone modification maps in the human frontal lobe link schizophrenia risk to the neuronal epigenome
Q61443156DNA methylation in the human frontal cortex reveals a putative mechanism for age-by-disease interactions
Q91786451Deconstructing and targeting the genomic architecture of human neurodegeneration
Q48066803Depression as a risk factor for Alzheimer's disease: Genes, steroids, cytokines and neurogenesis - What do we need to know?
Q58549216Early Life Stress and Epigenetics in Late-onset Alzheimer's Dementia: A Systematic Review
Q36648831Epigenetic Mechanisms of the Aging Human Retina
Q37590630Epigenetic dysregulation of brainstem nuclei in the pathogenesis of Alzheimer's disease: looking in the correct place at the right time?
Q39090345Epigenetics in Alzheimer's Disease: Perspective of DNA Methylation
Q26772028Epigenetics of Aging and Alzheimer's Disease: Implications for Pharmacogenomics and Drug Response
Q92712683Investigation of Gene Expression and DNA Methylation From Seven Different Brain Regions of a Crab-Eating Monkey as Determined by RNA-Seq and Whole-Genome Bisulfite Sequencing
Q37278503Novel regional age-associated DNA methylation changes within human common disease-associated loci
Q88978899Religious Orders Study and Rush Memory and Aging Project
Q90568230Reproductive period and epigenetic modifications of the oxidative phosphorylation pathway in the human prefrontal cortex
Q37294108Rescue of Early bace-1 and Global DNA Demethylation by S-Adenosylmethionine Reduces Amyloid Pathology and Improves Cognition in an Alzheimer's Model
Q38826595The epigenome in Alzheimer's disease: current state and approaches for a new path to gene discovery and understanding disease mechanism
Q38902491Time-dependent genetic effects on gene expression implicate aging processes

Search more.