Mesenchymal-specific deletion of C/EBPβ suppresses pulmonary fibrosis

scientific article

Mesenchymal-specific deletion of C/EBPβ suppresses pulmonary fibrosis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.AJPATH.2012.02.010
P932PMC publication ID3378850
P698PubMed publication ID22503555
P5875ResearchGate publication ID224037350

P2093author name stringZhe Wu
Biao Hu
Sem H Phan
Taku Nakashima
P2860cites workPathway analysis of coronary atherosclerosisQ38520286
Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and -12 in IL-13-induced inflammation and remodelingQ39735936
LAP (NF-IL6) transactivates the collagen alpha 1(I) gene from a 5' regulatory regionQ40345054
Expression and function of CCAAT/enhancer binding proteinbeta (C/EBPbeta) LAP and LIP isoforms in mouse mammary gland, tumors and cultured mammary epithelial cellsQ40786689
Mesenchymal cell survival in airway and interstitial pulmonary fibrosisQ41855310
Essential role of MMP-12 in Fas-induced lung fibrosisQ42375025
B220: a B cell-specific member of th T200 glycoprotein familyQ42800334
Alpha-smooth muscle actin is transiently expressed by myofibroblasts during experimental wound healing.Q44245074
C/EBPbeta associates with caspase 8 complex proteins and modulates apoptosis in hepatic stellate cellsQ46231484
Inducible lineage-specific deletion of TbetaRII in fibroblasts defines a pivotal regulatory role during adult skin wound healing.Q52587547
Characterization and regulation of RB6-8C5 antigen expression on murine bone marrow cellsQ64008476
A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the same mRNAQ68033053
Myofibroblasts from diverse pathologic settings are heterogeneous in their content of actin isoforms and intermediate filament proteinsQ69484732
A simplified method for the analysis of hydroxyproline in biological tissuesQ71346607
An essential role for CCAAT/enhancer binding protein beta in bleomycin-induced pulmonary fibrosisQ79440214
CCAAT/enhancer-binding protein beta isoforms and the regulation of alpha-smooth muscle actin gene expression by IL-1 betaQ80597399
An essential role for resident fibroblasts in experimental lung fibrosis is defined by lineage-specific deletion of high-affinity type II transforming growth factor β receptorQ84740460
The Papillomavirus E2 protein binds to and synergizes with C/EBP factors involved in keratinocyte differentiationQ24299766
CCAAT/enhancer-binding proteins: structure, function and regulationQ24534323
Ligand-activated site-specific recombination in miceQ24600193
The myofibroblast: one function, multiple originsQ24683749
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
A ribosomal S-6 kinase-mediated signal to C/EBP-beta is critical for the development of liver fibrosisQ27302244
Exploration, normalization, and summaries of high density oligonucleotide array probe level dataQ27861098
Phosphorylation of rat serine 105 or mouse threonine 217 in C/EBP beta is required for hepatocyte proliferation induced by TGF alphaQ28142640
F4/80, a monoclonal antibody directed specifically against the mouse macrophageQ28281328
CCAAT/enhancer-binding protein beta plays a regulatory role in differentiation and apoptosis of neuroblastoma cellsQ28512299
Smad3 mediates transforming growth factor-beta-induced alpha-smooth muscle actin expressionQ28573031
CCAAT/enhancer-binding protein mRNA is translated into multiple proteins with different transcription activation potentialsQ28579794
Gut-enriched Krüppel-like factor interaction with Smad3 inhibits myofibroblast differentiationQ28582127
Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouseQ29620355
Positive- and negative-acting Kruppel-like transcription factors bind a transforming growth factor beta control element required for expression of the smooth muscle cell differentiation marker SM22alpha in vivo.Q30305991
C/EBPalpha is critical for the neonatal acute-phase response to inflammationQ33781735
Epigenetic regulation of myofibroblast differentiation by DNA methylationQ33947144
Negative regulation of myofibroblast differentiation by PTEN (Phosphatase and Tensin Homolog Deleted on chromosome 10)Q34533889
The myofibroblast in pulmonary fibrosisQ35022198
FIZZ1 stimulation of myofibroblast differentiationQ35097457
C/EBP transcription factors in the lung epitheliumQ35213682
Evidence for early fibrosis and increased airway resistance in bone marrow transplant recipient mice deficient in MMP12.Q35325376
Ligand-dependent genetic recombination in fibroblasts : a potentially powerful technique for investigating gene function in fibrosisQ35748013
Macrophage elastase (MMP-12): a pro-inflammatory mediator?Q36165913
A potent far-upstream enhancer in the mouse pro alpha 2(I) collagen gene regulates expression of reporter genes in transgenic miceQ36237383
Structure, assembly and intracellular transport of the T cell receptor for antigen.Q36547069
The bleomycin animal model: a useful tool to investigate treatment options for idiopathic pulmonary fibrosis?Q36970923
Conditional ablation of C/EBP beta demonstrates its keratinocyte-specific requirement for cell survival and mouse skin tumorigenesisQ37172425
LAP (NF-IL-6), a tissue-specific transcriptional activator, is an inhibitor of hepatoma cell proliferation.Q37628853
Lymphoproliferative disorder and imbalanced T-helper response in C/EBP beta-deficient miceQ37696753
Krüppel-like factor 4 (KLF4/GKLF) is a target of bone morphogenetic proteins and transforming growth factor beta 1 in the regulation of vascular smooth muscle cell phenotype.Q38358459
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectpulmonary fibrosisQ32446
P304page(s)2257-2267
P577publication date2012-04-11
P1433published inThe American Journal of PathologyQ4744259
P1476titleMesenchymal-specific deletion of C/EBPβ suppresses pulmonary fibrosis
P478volume180

Reverse relations

cites work (P2860)
Q35837601Conditional Knockout of Telomerase Reverse Transcriptase in Mesenchymal Cells Impairs Mouse Pulmonary Fibrosis
Q47938517Deletion of NF-κB/RelA in Angiotensin II-Sensitive Mesenchymal Cells Blocks Aortic Vascular Inflammation and Abdominal Aortic Aneurysm Formation
Q92979120FAK signaling in cancer-associated fibroblasts promotes breast cancer cell migration and metastasis by exosomal miRNAs-mediated intercellular communication
Q53686964FOXM1 is a critical driver of lung fibroblast activation and fibrogenesis.
Q28392538Genetic tools for identifying and manipulating fibroblasts in the mouse
Q28085065Human genome-wide expression analysis reorients the study of inflammatory mediators and biomechanics in osteoarthritis
Q37304394Lung bone marrow-derived hematopoietic progenitor cells enhance pulmonary fibrosis
Q36240624Mesenchymal deficiency of Notch1 attenuates bleomycin-induced pulmonary fibrosis.
Q27022840Myofibroblasts
Q38795272Pulmonary fibrosis requires cell-autonomous mesenchymal fibroblast growth factor (FGF) signaling.
Q35816355Reemergence of hedgehog mediates epithelial-mesenchymal crosstalk in pulmonary fibrosis
Q47794291The Bleomycin Model of Pulmonary Fibrosis
Q90426312The serum amyloid A3 promoter-driven luciferase reporter mice is a valuable tool to image early renal fibrosis development and shows the therapeutic effect of glucosyl-hesperidin treatment
Q35034689Type V collagen induced tolerance suppresses collagen deposition, TGF-β and associated transcripts in pulmonary fibrosis

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