A structural snapshot of type II pilus formation in Streptococcus pneumoniae

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A structural snapshot of type II pilus formation in Streptococcus pneumoniae is …
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scholarly articleQ13442814

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P356DOI10.1074/JBC.M115.647834
P932PMC publication ID4566232
P698PubMed publication ID26198632

P50authorAndréa DessenQ28039279
Guy SchoehnQ37372598
Anne Marie Di GuilmiQ43072547
Daniel Maragno TrindadeQ57152493
Daphna FenelQ114446853
P2093author name stringMd Munan Shaik
Charlotte Lombardi
P2860cites workCrystal structure of Spy0129, a Streptococcus pyogenes class B sortase involved in pilus assemblyQ21135758
A pneumococcal pilus influences virulence and host inflammatory responsesQ24538990
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A second pilus type in Streptococcus pneumoniae is prevalent in emerging serotypes and mediates adhesion to host cellsQ24651147
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Intramolecular isopeptide bonds give thermodynamic and proteolytic stability to the major pilin protein of Streptococcus pyogenesQ24655883
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Sortase-mediated pilus fiber biogenesis in Streptococcus pneumoniaeQ27653154
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Structural basis of host cell recognition by the pilus adhesin from Streptococcus pneumoniaeQ27659801
Crystal Structure of the Minor Pilin FctB Reveals Determinants of Group A Streptococcal Pilus AnchoringQ27660983
A Highly Unusual Thioester Bond in a Pilus Adhesin Is Required for Efficient Host Cell InteractionQ27664121
Structure of the Full-Length Major Pilin from Streptococcus pneumoniae: Implications for Isopeptide Bond Formation in Gram-Positive Bacterial PiliQ27670807
Structural Differences between the Streptococcus agalactiae Housekeeping and Pilus-Specific Sortases: SrtA and SrtC1Q27673780
Structural Basis for Group B Streptococcus Pilus 1 Sortases C Regulation and SpecificityQ27675094
The full-length Streptococcus pneumoniae major pilin RrgB crystallizes in a fibre-like structure, which presents the D1 isopeptide bond and provides details on the mechanism of pilus polymerizationQ27675142
The Crystal Structure Analysis of Group B Streptococcus Sortase C1: A Model for the “Lid” Movement upon Substrate BindingQ27675265
Structural and computational studies of the Staphylococcus aureus sortase B-substrate complex reveal a substrate-stabilized oxyanion holeQ27681683
Structural Basis of Pilus Anchoring by the Ancillary Pilin RrgC of Streptococcus pneumoniaeQ27683515
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Pneumococcal pili are composed of protofilaments exposing adhesive clusters of Rrg AQ28472283
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Proteinaceous determinants of surface colonization in bacteria: bacterial adhesion and biofilm formation from a protein secretion perspective.Q30354618
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Molecular architecture of Streptococcus pneumoniae TIGR4 piliQ33553003
Mitis group streptococci express variable pilus islet 2 piliQ34038015
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Pili in Gram-negative and Gram-positive bacteria - structure, assembly and their role in disease.Q34866500
Increase in pilus islet 2-encoded pili among Streptococcus pneumoniae isolates, Atlanta, Georgia, USA.Q34908016
Solution structure of the major (Spy0128) and minor (Spy0125 and Spy0130) pili subunits from Streptococcus pyogenes.Q34963550
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Structural determinants of Actinomyces sortase SrtC2 required for membrane localization and assembly of type 2 fimbriae for interbacterial coaggregation and oral biofilm formation.Q35943246
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Iterative-build OMIT maps: map improvement by iterative model building and refinement without model biasQ36713744
Pilin and sortase residues critical for endocarditis- and biofilm-associated pilus biogenesis in Enterococcus faecalisQ37253028
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Staphylococcus aureus Sortase A transpeptidase. Calcium promotes sorting signal binding by altering the mobility and structure of an active site loop.Q38319154
RrgA and RrgB are components of a multisubunit pilus encoded by the Streptococcus pneumoniae rlrA pathogenicity isletQ41970933
Anchoring of surface proteins to the cell wall of Staphylococcus aureus. Cysteine 184 and histidine 120 of sortase form a thiolate-imidazolium ion pair for catalysisQ43803650
Passage of heme-iron across the envelope of Staphylococcus aureus.Q44307087
Staphylococcus aureus sortase transpeptidase SrtA: insight into the kinetic mechanism and evidence for a reverse protonation catalytic mechanismQ46651137
ClusPro: an automated docking and discrimination method for the prediction of protein complexesQ48565772
Group B Streptococcus pilus sortase regulation: a single mutation in the lid region induces pilin protein polymerization in vitro.Q51029482
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Association of RrgA and RrgC into the Streptococcus pneumoniae pilus by sortases C-2 and C-3.Q54347847
Pneumococcal immune adherence to human erythrocytesQ73005007
Two-stage PCR protocol allowing introduction of multiple mutations, deletions and insertions using QuikChange Site-Directed MutagenesisQ77798021
Mutational analysis of active site residues in the Staphylococcus aureus transpeptidase SrtAQ80368756
P433issue37
P407language of work or nameEnglishQ1860
P921main subjectStreptococcus pneumoniaeQ221179
P304page(s)22581-22592
P577publication date2015-07-21
P1433published inJournal of Biological ChemistryQ867727
P1476titleA structural snapshot of type II pilus formation in Streptococcus pneumoniae
P478volume290

Reverse relations

cites work (P2860)
Q64448249A comprehensive in silico analysis of sortase superfamily
Q40076026A plasmid from an Antarctic haloarchaeon uses specialized membrane vesicles to disseminate and infect plasmid-free cells
Q38994957Bacterial pili, with emphasis on Mycobacterium tuberculosis curli pili: potential biomarkers for point-of care tests and therapeutics
Q57139235Bent conformation of a backbone pilin N-terminal domain supports a three-stage pilus assembly mechanism
Q36098753Comparative Genomics Analysis of Streptococcus tigurinus Strains Identifies Genetic Elements Specifically and Uniquely Present in Highly Virulent Strains
Q30061569Discovery of Novel Leptospirosis Vaccine Candidates Using Reverse and Structural Vaccinology.
Q40111117Molecular characterization of Streptococcus pneumoniae, particularly serotype19A/ST320, that emerged in Krasnoyarsk, Russia
Q37044522New insights about pilus formation in gut-adapted Lactobacillus rhamnosus GG from the crystal structure of the SpaA backbone-pilin subunit.
Q38792356Pilus biogenesis of Gram-positive bacteria: Roles of sortases and implications for assembly
Q39418899Sortase Transpeptidases: Structural Biology and Catalytic Mechanism

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