scholarly article | Q13442814 |
P2093 | author name string | Y Altschuler | |
H S White | |||
J G Lamb | |||
B Yagen | |||
M Bialer | |||
E Fibach | |||
S Eyal | |||
M Smith-Yockman | |||
P2860 | cites work | Protein measurement with the Folin phenol reagent | Q20900776 |
Transcriptional regulation of human CYP3A4 basal expression by CCAAT enhancer-binding protein alpha and hepatocyte nuclear factor-3 gamma | Q24299883 | ||
An epigenetic mouse model for molecular and behavioral neuropathologies related to schizophrenia vulnerability | Q24544035 | ||
Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues | Q24633406 | ||
Histone acetylation and histone deacetylase activity of magnesium valproate in tumor and peripheral blood of patients with cervical cancer. A phase I study | Q24810933 | ||
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction | Q25938986 | ||
The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux | Q28186424 | ||
Multidrug resistance in cancer: role of ATP-dependent transporters | Q28208049 | ||
Clinical development of histone deacetylase inhibitors as anticancer agents | Q28244438 | ||
Asymmetric synthesis and enantioselective teratogenicity of 2-n-propyl-4-pentenoic acid (4-en-VPA), an active metabolite of the anticonvulsant drug, valproic acid | Q28341501 | ||
Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells | Q28366303 | ||
Modulation of mdr1a and CYP3A gene expression in the intestine and liver as possible cause of changes in the cyclosporin A disposition kinetics by dexamethasone | Q28572425 | ||
Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen | Q29616224 | ||
Induction of P-glycoprotein mRNA transcripts by cycloheximide in animal tissues: evidence that class I Pgp is transcriptionally regulated whereas class II Pgp is post-transcriptionally regulated | Q32054582 | ||
Transcriptional regulation of the MDR1 gene by histone acetyltransferase and deacetylase is mediated by NF-Y. | Q33775085 | ||
Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites | Q33832954 | ||
Pharmacokinetic-pharmacodynamic relationships of (2S,3S)-valnoctamide and its stereoisomer (2R,3S)-valnoctamide in rodent models of epilepsy | Q34226515 | ||
Rational development of histone deacetylase inhibitors as anticancer agents: a review | Q34426444 | ||
A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants | Q34488592 | ||
Therapeutic drug monitoring of the newer antiepileptic drugs | Q35135903 | ||
Clinically important drug interactions in epilepsy: general features and interactions between antiepileptic drugs | Q35172260 | ||
Clinically important drug interactions in epilepsy: interactions between antiepileptic drugs and other drugs | Q35183961 | ||
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MDR1, chemotherapy and chromatin remodeling. | Q35869829 | ||
Evolving anticancer drug valproic acid: insights into the mechanism and clinical studies. | Q36002354 | ||
Isolation of mammalian heterochromatin and euchromatin. | Q39870751 | ||
Depsipeptide-resistant KU812 cells show reversible P-glycoprotein expression, hyper-acetylated histones, and modulated gene expression profile | Q40356263 | ||
Up-regulation of MDR1 and induction of doxorubicin resistance by histone deacetylase inhibitor depsipeptide (FK228) and ATRA in acute promyelocytic leukemia cells | Q40381466 | ||
Epigenetic changes to the MDR1 locus in response to chemotherapeutic drugs | Q40386853 | ||
Antileukemia activity of the combination of 5-aza-2'-deoxycytidine with valproic acid | Q40415058 | ||
Histone deacetylases inhibition and tumor cells cytotoxicity by CNS-active VPA constitutional isomers and derivatives | Q40429957 | ||
Chemoresistance to depsipeptide FK228 [(E)-(1S,4S,10S,21R)-7-[(Z)-ethylidene]-4,21-diisopropyl-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8,7,6]-tricos-16-ene-3,6,9,22-pentanone] is mediated by reversible MDR1 induction in human cancer cell lines | Q40434292 | ||
Efflux of depsipeptide FK228 (FR901228, NSC-630176) is mediated by P-glycoprotein and multidrug resistance-associated protein 1. | Q40474222 | ||
T-cell lymphoma as a model for the use of histone deacetylase inhibitors in cancer therapy: impact of depsipeptide on molecular markers, therapeutic targets, and mechanisms of resistance | Q40583269 | ||
Comparison of detoxification enzyme mRNAs in woodrats (Neotoma lepida) and laboratory rats | Q40697918 | ||
Can we develop improved derivatives of valproic acid? | Q40739202 | ||
Glutathione S-transferases and P-glycoprotein in normal rat hepatocytes and hepatoma cells: analysis using flow cytometry | Q41442316 | ||
Further branching of valproate-related carboxylic acids reduces the teratogenic activity, but not the anticonvulsant effect | Q42553750 | ||
Protein expression analysis of drug-mediated hepatotoxicity in the Sprague-Dawley rat. | Q44222991 | ||
Histone Deacetylase Inhibition by Sodium Butyrate Chemotherapy Ameliorates the Neurodegenerative Phenotype in Huntington's Disease Mice | Q44619618 | ||
Histone deacetylase is a target of valproic acid-mediated cellular differentiation | Q44761814 | ||
Correlation analysis between anticonvulsant ED50 values of antiepileptic drugs in mice and rats and their therapeutic doses and plasma levels | Q45176492 | ||
Modulation of the expression of a multidrug resistance gene (mdr-1/P-glycoprotein) by differentiating agents. | Q45825109 | ||
CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice | Q46573657 | ||
Valproic acid and all-trans retinoic acid for the treatment of elderly patients with acute myeloid leukemia | Q46582778 | ||
Pharmacokinetics and metabolism of a new potent antiepileptic drug, 2,2,3,3-tetramethycyclopropanecarbonylurea, in rats | Q46613328 | ||
Modulation of P-glycoprotein expression by cytochrome P450 3A inducers in male and female rat livers. | Q50900871 | ||
On the inhibitory action of mersalyl on microsomal drug oxidation: a rigid organization of the electron transport chain. | Q51682719 | ||
Variable effects of sodium butyrate on the expression and function of the MDR1 (P-glycoprotein) gene in colon carcinoma cell lines. | Q54231075 | ||
The enantiomers of the valproic acid analogue 2-n-propyl-4-pentynoic acid (4-yn-VPA): asymmetric synthesis and highly stereoselective teratogenicity in mice | Q67583915 | ||
Disposition of valpromide, valproic acid, and valnoctamide in the brain, liver, plasma, and urine of rats | Q71302790 | ||
Lack of correlation between expression and function of P-glycoprotein in acute myeloid leukemia cell lines | Q72285466 | ||
Valnoctamide, valpromide and valnoctic acid are much less teratogenic in mice than valproic acid | Q74463323 | ||
P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 250-260 | |
P577 | publication date | 2006-08-07 | |
P1433 | published in | British Journal of Pharmacology | Q919631 |
P1476 | title | The antiepileptic and anticancer agent, valproic acid, induces P-glycoprotein in human tumour cell lines and in rat liver | |
P478 | volume | 149 |
Q38868683 | Antiepileptic drugs alter the expression of placental carriers: An in vitro study in a human placental cell line |
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Q50562638 | Drug-Drug Interaction Studies of Paliperidone and Divalproex Sodium Extended-Release Tablets in Healthy Participants and Patients with Psychiatric Disorders. |
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Q39332767 | Nonclinical toxicological evaluation of occidiofungin, a unique glycolipopeptide antifungal |
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