The role of alpha-synuclein in neurodegenerative diseases

scientific article

The role of alpha-synuclein in neurodegenerative diseases is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/J.PHARMTHERA.2004.10.010
P698PubMed publication ID15737408

P2093author name stringM Catherine Bennett
P2860cites workMutations in the parkin gene cause autosomal recessive juvenile parkinsonismQ24309753
Parkinsonism: a clinical marker of exposure to neurotoxinsQ39573876
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectSynucleinQ24767155
neurodegenerationQ1755122
P304page(s)311-331
P577publication date2004-12-08
P1433published inPharmacology & TherapeuticsQ3378596
P1476titleThe role of alpha-synuclein in neurodegenerative diseases
P478volume105

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cites work (P2860)
Q92927768APOE genotype influences the gut microbiome structure and function in humans and mice: relevance for Alzheimer's disease pathophysiology
Q46666592Acridine derivatives inhibit lysozyme aggregation.
Q42444692Aging and alpha-synuclein affect synaptic plasticity in the dentate gyrus.
Q37386416Alpha-synuclein immunopositive aggregates in the myenteric plexus of the aging Fischer 344 rat.
Q35139572Alpha-synuclein in peripheral tissues and body fluids as a biomarker for Parkinson's disease - a systematic review
Q48274235Alpha-synuclein induced membrane depolarization and loss of phosphorylation capacity of isolated rat brain mitochondria: implications in Parkinson's disease
Q36554589Alpha-synuclein pathology and axonal degeneration of the peripheral motor nerves innervating pharyngeal muscles in Parkinson disease
Q37020862Alpha-synuclein-immunopositive myenteric neurons and vagal preganglionic terminals: autonomic pathway implicated in Parkinson's disease?
Q30424486Anesthesia-induced developmental neurodegeneration: the role of neuronal organelles
Q64865563Asiatic Acid Prevents Oxidative Stress and Apoptosis by Inhibiting the Translocation of α-Synuclein Into Mitochondria
Q24323344Attenuation of the norepinephrine transporter activity and trafficking via interactions with alpha-synuclein
Q36520931Catabolic insufficiency and aging
Q47587631Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry
Q43256880Characterization of intrinsically disordered proteins with electrospray ionization mass spectrometry: conformational heterogeneity of alpha-synuclein
Q37715960Computational approaches to understanding protein aggregation in neurodegeneration
Q64123712Conservation of the Amyloid Interactome Across Diverse Fibrillar Structures
Q48440013Cytosolic proteins regulate alpha-synuclein dissociation from presynaptic membranes.
Q33755817DJ-1 deficient mice demonstrate similar vulnerability to pathogenic Ala53Thr human alpha-syn toxicity
Q33715071Decreased Expression of α-Synuclein, Nogo-A and UCH-L1 in Patients with Schizophrenia: A Preliminary Serum Study
Q90738392Degeneration of dopaminergic circuitry influences depressive symptoms in Lewy body disorders
Q34656396EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers
Q35681438Effect of lysosomal and ubiquitin-proteasome system dysfunction on the abnormal aggregation of α-synuclein in PC12 cells
Q43169449Effects of dithiothreitol on the amyloid fibrillogenesis of hen egg-white lysozyme
Q28732131Excess α-synuclein worsens disease in mice lacking ubiquitin carboxy-terminal hydrolase L1
Q37232067Immunological features of alpha-synuclein in Parkinson's disease
Q39368611Impact of Non-Enzymatic Glycation in Neurodegenerative Diseases: Role of Natural Products in Prevention.
Q28283547Impact of newer pharmacological treatments on quality of life in patients with Parkinson's disease
Q35172657Improved immunodetection of endogenous α-synuclein
Q36872892Interactions between metals and alpha-synuclein--function or artefact?
Q48485896Intranigral dopamine toxicity and alpha-synuclein response in rats.
Q38044422Intrinsic disorder in proteins: a challenge for (un)structural biology met by ion mobility-mass spectrometry
Q46173279Lessons learned from protein aggregation: toward technological and biomedical applications.
Q34478663Lewy bodies
Q37079830Lysosomes in iron metabolism, ageing and apoptosis
Q35992475Macrophages associated with the intrinsic and extrinsic autonomic innervation of the rat gastrointestinal tract
Q33366459Mechanisms of hybrid oligomer formation in the pathogenesis of combined Alzheimer's and Parkinson's diseases
Q36727241Mitochondrial import and accumulation of alpha-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain
Q37556779Mitochondrial trafficking of APP and alpha synuclein: Relevance to mitochondrial dysfunction in Alzheimer's and Parkinson's diseases
Q37570507Mitochondrial turnover and aging of long-lived postmitotic cells: the mitochondrial-lysosomal axis theory of aging
Q31165000Modelling Ser129 phosphorylation inhibits membrane binding of pore-forming alpha-synuclein oligomers
Q24298523Modulation of the trafficking of the human serotonin transporter by human alpha-synuclein
Q37350413Molecular and cellular biology of synucleins
Q37472670Molecular mechanism of active zone organization at vertebrate neuromuscular junctions
Q37003479Multiple system atrophy: alpha-synuclein and neuronal degeneration
Q34648491Neuropathology, biochemistry, and biophysics of alpha-synuclein aggregation
Q47097416Omics Approaches for Identifying Physiological Adaptations to Genome Instability in Aging
Q39716036Oxidative stress partially contributes to iron-induced α-synuclein aggregation in SK-N-SH cells
Q39416222Parkinson's disease: genetics and beyond
Q48246699Phosphorylated α-Synuclein-Copper Complex Formation in the Pathogenesis of Parkinson's Disease
Q42958291Photo-activity induced by amyloidogenesis
Q37166339Physiological and pathological role of alpha-synuclein in Parkinson's disease through iron mediated oxidative stress; the role of a putative iron-responsive element
Q38923732Prolyl oligopeptidase enhances α-synuclein dimerization via direct protein-protein interaction
Q24311624Proteomics analysis identifies phosphorylation-dependent alpha-synuclein protein interactions
Q35241298Proteomics in neurodegenerative diseases: Methods for obtaining a closer look at the neuronal proteome
Q38028366Rifampicin and Parkinson's disease
Q36731472Role of Ser129 phosphorylation of α-synuclein in melanoma cells
Q37587111Role of α-synuclein penetration into the membrane in the mechanisms of oligomer pore formation
Q30357845Sensitivity of secondary structure propensities to sequence differences between alpha- and gamma-synuclein: implications for fibrillation
Q38039857Targeting the chameleon: a focused look at α-synuclein and its roles in neurodegeneration
Q30422273The abolishment of anesthesia-induced cognitive impairment by timely protection of mitochondria in the developing rat brain: the importance of free oxygen radicals and mitochondrial integrity
Q46316816The long noncoding RNA Malat1: Its physiological and pathophysiological functions
Q37809751Vulnerability of mesostriatal dopaminergic neurons in Parkinson's disease
Q40274137gamma-synuclein has a dynamic intracellular localization
Q28572683α-Synuclein negatively regulates protein kinase Cδ expression to suppress apoptosis in dopaminergic neurons by reducing p300 histone acetyltransferase activity
Q38947516α-Synuclein-induced mitochondrial dysfunction in isolated preparation and intact cells: implications in the pathogenesis of Parkinson's disease
Q33889446α-synuclein reactive antibodies as diagnostic biomarkers in blood sera of Parkinson's disease patients.

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