Autophagy: an emerging immunological paradigm

scientific article

Autophagy: an emerging immunological paradigm is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4049/JIMMUNOL.1102108
P932PMC publication ID3382968
P698PubMed publication ID22723639
P5875ResearchGate publication ID227858075

P50authorVojo DereticQ7939853
P2860cites workImage-based genome-wide siRNA screen identifies selective autophagy factorsQ24294407
Inhibition of autophagy by TAB2 and TAB3Q24297091
Endogenous HMGB1 regulates autophagyQ24298865
Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasionQ24301905
Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destructionQ24303900
Phosphorylation of the autophagy receptor optineurin restricts Salmonella growthQ24304447
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other lociQ24306903
Active caspase-1 is a regulator of unconventional protein secretionQ24308770
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controlsQ24550675
Autophagy in immunity and inflammationQ24595707
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controlsQ24628710
p62 and NDP52 proteins target intracytosolic Shigella and Listeria to different autophagy pathwaysQ24629208
Human IRGM regulates autophagy and cell-autonomous immunity functions through mitochondriaQ24631535
Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune responseQ24643548
Autophagy, Immunity, and Microbial AdaptationsQ27489075
A role for mitochondria in NLRP3 inflammasome activationQ28131794
Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosusQ28261767
TRAF6 and A20 regulate lysine 63-linked ubiquitination of Beclin-1 to control TLR4-induced autophagyQ28585634
A family of IFN-γ-inducible 65-kD GTPases protects against bacterial infectionQ28593668
Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1βQ29030555
The role of Atg proteins in autophagosome formationQ29547418
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasomeQ29547419
Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophagesQ29547420
Autophagy-dependent viral recognition by plasmacytoid dendritic cellsQ29614177
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta productionQ29614472
Human IRGM induces autophagy to eliminate intracellular mycobacteriaQ29614486
TFEB links autophagy to lysosomal biogenesisQ29614835
Autophagy-dependent anticancer immune responses induced by chemotherapeutic agents in miceQ29615615
NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentationQ29615617
Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entryQ29615618
The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteriaQ29615619
Autophagy defends cells against invading group A StreptococcusQ29615620
Human leucine-rich repeat proteins: a genome-wide bioinformatic categorization and functional analysis in innate immunityQ30499032
A Diacylglycerol-Dependent Signaling Pathway Contributes to Regulation of Antibacterial AutophagyQ30540202
Unconventional secretion of Pichia pastoris Acb1 is dependent on GRASP protein, peroxisomal functions, and autophagosome formation.Q33689637
Targeted activation of innate immunity for therapeutic induction of autophagy and apoptosis in melanoma cellsQ33775637
Human immunodeficiency virus-1 inhibition of immunoamphisomes in dendritic cells impairs early innate and adaptive immune responsesQ34089158
A comprehensive analysis of shared loci between systemic lupus erythematosus (SLE) and sixteen autoimmune diseases reveals limited genetic overlapQ34102802
HMGB1 release and redox regulates autophagy and apoptosis in cancer cellsQ34154797
The class IA phosphatidylinositol 3-kinase p110-β subunit is a positive regulator of autophagyQ34317015
In vivo requirement for Atg5 in antigen presentation by dendritic cellsQ34376166
Macroautophagy regulates energy metabolism during effector T cell activationQ34615092
Autophagy in immunity and cell-autonomous defense against intracellular microbesQ34673845
Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradationQ34684708
Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis riskQ35125868
Autophagy in antigen-presenting cells results in presentation of citrullinated peptides to CD4 T cellsQ35627649
Lysosomal killing of Mycobacterium mediated by ubiquitin-derived peptides is enhanced by autophagyQ35749637
Autophagy as an innate immunity paradigm: expanding the scope and repertoire of pattern recognition receptors.Q35785827
The Atg5 Atg12 conjugate associates with innate antiviral immune responsesQ35956883
A critical role for the autophagy gene Atg5 in T cell survival and proliferationQ36228924
Autophagic control of listeria through intracellular innate immune recognition in drosophilaQ36925388
The B cell receptor governs the subcellular location of Toll-like receptor 9 leading to hyperresponses to DNA-containing antigensQ37012927
NLRP4 negatively regulates autophagic processes through an association with beclin1.Q39611705
Autophagy protects against Sindbis virus infection of the central nervous systemQ39738841
Listeria monocytogenes ActA-mediated escape from autophagic recognitionQ39800150
Delivery of cytosolic components by autophagic adaptor protein p62 endows autophagosomes with unique antimicrobial properties.Q39837169
The class III kinase Vps34 promotes T lymphocyte survival through regulating IL-7Rα surface expressionQ40073010
Endogenous MHC class II processing of a viral nuclear antigen after autophagy.Q40481959
Autophagy regulates endoplasmic reticulum homeostasis and calcium mobilization in T lymphocytesQ41486560
Autophagy is required to maintain muscle mass.Q51411361
Temporal regulation of intracellular organelle homeostasis in T lymphocytes by autophagy.Q54382111
Genetic variation in the autophagy gene ULK1 and risk of Crohn's disease.Q55054234
Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for toleranceQ56701390
Shigella phagocytic vacuolar membrane remnants participate in the cellular response to pathogen invasion and are regulated by autophagyQ84410016
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectautophagyQ288322
P304page(s)15-20
P577publication date2012-07-01
P1433published inJournal of ImmunologyQ3521441
P1476titleAutophagy: an emerging immunological paradigm
P478volume189

Reverse relations

cites work (P2860)
Q38824253A LC3-interacting motif in the influenza A virus M2 protein is required to subvert autophagy and maintain virion stability
Q35926529A conserved mechanism of TOR-dependent RCK-mediated mRNA degradation regulates autophagy.
Q37565010AIM2 inhibits autophagy and IFN-β production during M. bovis infection
Q36558745Active escape of Orientia tsutsugamushi from cellular autophagy
Q47701304An Update on Host-Pathogen Interplay and Modulation of Immune Responses during Orientia tsutsugamushi Infection.
Q38705160Assessing Autophagy in Mouse Models and Patients with Systemic Autoimmune Diseases
Q35269455Atg5 but not Atg7 in dendritic cells enhances IL-2 and IFN-γ production by Toxoplasma gondii-reactive CD4+ T cells
Q30530554Autophagosomes induced by a bacterial Beclin 1 binding protein facilitate obligatory intracellular infection
Q60912923Autophagy and Its Role in Protein Secretion: Implications for Cancer Therapy
Q36764500Autophagy and autoimmunity crosstalks
Q37844980Autophagy and female genital tract infections: new insights and research directions
Q35557084Autophagy as a modulator and target in prostate cancer
Q38116134Autophagy as an immune effector against tuberculosis
Q34981436Autophagy enhances bacterial clearance during P. aeruginosa lung infection
Q34541457Autophagy gene Atg16L1 prevents lethal T cell alloreactivity mediated by dendritic cells
Q38134372Autophagy in blood cancers: biological role and therapeutic implications.
Q29248363Autophagy in infection, inflammation, and immunity
Q37724992Autophagy in macrophages: impacting inflammation and bacterial infection
Q57179592Autophagy in the Infected Cell: Insights from Pathogenic Bacteria
Q28390423Autophagy inhibition by sustained overproduction of IL6 contributes to arsenic carcinogenesis
Q90056484Autophagy inhibition via Becn1 downregulation improves the mesenchymal stem cells antifibrotic potential in experimental liver fibrosis
Q59335898Autophagy is a gatekeeper of hepatic differentiation and carcinogenesis by controlling the degradation of Yap
Q38204787Autophagy mediates neutrophil responses to bacterial infection
Q34373059Autophagy plays an important role in the containment of HIV-1 in nonprogressor-infected patients.
Q24609294Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation
Q41810196Autophagy: An Integral Component of the Mammalian Stress Response
Q38123527Autophagy: a crucial moderator of redox balance, inflammation, and apoptosis in lung disease
Q37462492Crosstalk between autophagy and inflammasomes
Q42223966Dendritic cells in IBD pathogenesis: an area of therapeutic opportunity?
Q36562107Deubiquitinases regulate the activity of caspase-1 and interleukin-1β secretion via assembly of the inflammasome
Q37679218Divergent roles of autophagy in virus infection
Q89471123Effects of AANAT overexpression on the inflammatory responses and autophagy activity in the cellular and transgenic animal levels
Q34961788Francisella tularensis harvests nutrients derived via ATG5-independent autophagy to support intracellular growth
Q37107125Functions of autophagy in normal and diseased liver
Q35034843Glucose and palmitate uncouple AMPK from autophagy in human aortic endothelial cells
Q35145550Host and bacterial proteins that repress recruitment of LC3 to Shigella early during infection
Q28552188Identification of a Transcription Factor That Regulates Host Cell Exit and Virulence of Mycobacterium tuberculosis
Q41842932Inflammatory bowel disease: An archetype disorder of outer environment sensor systems
Q45344347Inhibition of autophagy by sera from pregnant women
Q36862693Insulin-degrading enzyme secretion from astrocytes is mediated by an autophagy-based unconventional secretory pathway in Alzheimer disease.
Q37581394Key roles of autophagy in regulating T-cell function
Q36655722LAMP-2C Inhibits MHC Class II Presentation of Cytoplasmic Antigens by Disrupting Chaperone-Mediated Autophagy
Q38770084Markers of immune-mediated inflammation in the brains of young adults and adolescents with type 1 diabetes and fatal diabetic ketoacidosis. Is there a difference?
Q49612593Mechanisms, pathophysiological roles and methods for analyzing mitophagy - recent insights
Q35677564Methicillin-resistant Staphylococcus aureus adaptation to human keratinocytes
Q37714034Mitophagy enhances oncolytic measles virus replication by mitigating DDX58/RIG-I-like receptor signaling
Q38043052Mitophagy or how to control the Jekyll and Hyde embedded in mitochondrial metabolism: implications for melanoma progression and drug resistance
Q37114392Molecular and genetic inflammation networks in major human diseases.
Q55024984NF-κB-Mediated Inflammation in the Pathogenesis of Intracranial Aneurysm and Subarachnoid Hemorrhage. Does Autophagy Play a Role?
Q38104885Pathogen-induced autophagy signaling in innate immunity.
Q35534254Phosphoinositide-3 kinase inhibition modulates responses to rhinovirus by mechanisms that are predominantly independent of autophagy
Q92399602Pleiotropic roles of autophagy in stem cell-based therapies
Q37440135Purinergic receptor X7 is a key modulator of metabolic oxidative stress-mediated autophagy and inflammation in experimental nonalcoholic steatohepatitis.
Q64951839Rainbow Trout Red Blood Cells Exposed to Viral Hemorrhagic Septicemia Virus Up-Regulate Antigen-Processing Mechanisms and MHC I&II, CD86, and CD83 Antigen-presenting Cell Markers.
Q37032282Redox control of inflammation in macrophages
Q35853108Regulation of autophagy by E3 ubiquitin ligase RNF216 through BECN1 ubiquitination
Q60046078Restriction Factors: From Intrinsic Viral Restriction to Shaping Cellular Immunity Against HIV-1
Q34400723Risk factors for pancreatic cancer: underlying mechanisms and potential targets
Q88633708Role of Myeloid Lineage Cell Autophagy in Ischemic Brain Injury
Q26753001Roles of the Picornaviral 3C Proteinase in the Viral Life Cycle and Host Cells
Q54247042SFTS phlebovirus promotes LC3-II accumulation and nonstructural protein of SFTS phlebovirus co-localizes with autophagy proteins.
Q38070134Self-eating and self-defense: autophagy controls innate immunity and adaptive immunity.
Q52645929TANK-Binding Kinase 1-Dependent Responses in Health and Autoimmunity.
Q29030353TBK-1 Promotes Autophagy-Mediated Antimicrobial Defense by Controlling Autophagosome Maturation
Q48559615The Mitochondria-Regulated Immune Pathway Activated in the C. elegans Intestine Is Neuroprotective.
Q27026138The cooperation between the autophagy machinery and the inflammasome to implement an appropriate innate immune response: do they regulate each other?
Q28540241The emerging potential of autophagy-based therapies in the treatment of cystic fibrosis lung infections
Q37109549The multifaceted role of autophagy in tumor evasion from immune surveillance
Q36793466Thinking laterally about neurodegenerative proteinopathies
Q36759434Tissue-resident dendritic cells and diseases involving dendritic cell malfunction
Q38743924Tregs restrain dendritic cell autophagy to ameliorate autoimmunity.
Q38967400UBE2L6/UBCH8 and ISG15 attenuate autophagy in esophageal cancer cells
Q26851723Why should autophagic flux be assessed?
Q90073579[Role of autophagy in the pathogenesis of periodontitis]

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