Desialylation of Spermatozoa and Epithelial Cell Glycocalyx Is a Consequence of Bacterial Infection of the Epididymis

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Desialylation of Spermatozoa and Epithelial Cell Glycocalyx Is a Consequence of Bacterial Infection of the Epididymis is …
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scholarly articleQ13442814

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P356DOI10.1074/JBC.M116.718072
P932PMC publication ID5016166
P698PubMed publication ID27339898

P2093author name stringAdrian Pilatz
Andreas Meinhardt
Vera Michel
Sudhanshu Bhushan
Christina E Galuska
Hans-Christian Schuppe
Farhad Khosravi
Sebastian P Galuska
Philipp Christian
P2860cites workEpididymitis: revelations at the convergence of clinical and basic sciencesQ26829992
Neuraminidase induces capacitation and acrosome reaction in mammalian spermatozoaQ46170536
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Three cases of xanthogranulomatous epididymitis caused by E. coli.Q53595516
The release of hyaluronidase from guinea-pig spermatozoa during the course of the normal acrosome reaction in vitro.Q54007955
Glycomic strategy for efficient linkage analysis of di-, oligo- and polysialic acids.Q54333865
Loss of sperm surface sialic acid induces phagocytosis: an assay with a monoclonal antibody T21, which recognizes a 54K sialoglycoproteinQ68061030
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Fluorometric high-performance liquid chromatography of N-acetyl- and N-glycolylneuraminic acids and its application to their microdetermination in human and animal sera, glycoproteins, and glycolipidsQ69437666
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Acrosome intactness and seminal hyaluronidase activity: relationship with conventional seminal parametersQ74302212
Sialic acids: fascinating sugars in higher animals and manQ81622175
Artificial and natural sialic acid precursors influence the angiogenic capacity of human umbilical vein endothelial cellsQ86206389
Sugar-coated sperm: Unraveling the functions of the mammalian sperm glycocalyxQ27001029
Structural basis for sialic acid-mediated self-recognition by complement factor HQ27696183
Sperm swim-up techniques and DNA fragmentationQ28214695
Human sperm binding is mediated by the sialyl-Lewis(x) oligosaccharide on the zona pellucidaQ28245912
Siglecs and their roles in the immune systemQ28294469
Uropathogenic Escherichia coli block MyD88-dependent and activate MyD88-independent signaling pathways in rat testicular cellsQ28574753
Quantification of nucleotide-activated sialic acids by a combination of reduction and fluorescent labelingQ33568028
Factor H in porcine seminal plasma protects sperm against complement attack in genital tractsQ33582067
Amelioration of sepsis by inhibiting sialidase-mediated disruption of the CD24-SiglecG interaction.Q33874812
Uropathogenic E. coli induce different immune response in testicular and peritoneal macrophages: implications for testicular immune privilegeQ34099251
Multifarious roles of sialic acids in immunityQ34270155
Siglec-mediated regulation of immune cell function in disease.Q34314957
Chemical diversity in the sialic acids and related alpha-keto acids: an evolutionary perspective.Q34527437
The affinity of the FimH fimbrial adhesin is receptor-driven and quasi-independent of Escherichia coli pathotypesQ35103730
Epididymitis: ascending infection restricted by segmental boundariesQ35637352
Neuraminidase-Dependent Degradation of Polysialic Acid Is Required for the Lamination of Newly Generated NeuronsQ35885507
Anti-inflammatory activity of low molecular weight polysialic acid on human macrophagesQ36297820
Sialidases on mammalian sperm mediate deciduous sialylation during capacitationQ36368281
Epididymosomes are involved in the acquisition of new sperm proteins during epididymal transitQ36858965
Experimental epididymitis due to Chlamydia trachomatis in ratsQ36946057
Polysialic acid is present in mammalian semen as a post-translational modification of the neural cell adhesion molecule NCAM and the polysialyltransferase ST8SiaII.Q36967286
Sialylation Facilitates the Maturation of Mammalian Sperm and Affects Its Survival in Female Uterus.Q37098526
CD24 and Siglec-10 selectively repress tissue damage-induced immune responses.Q37396101
Sialic acids as regulators of molecular and cellular interactionsQ37584349
Complement C3 convertase: Cell surface restriction of β1H control and generation of restriction on neuraminidase-treated cellsQ37586846
Acute epididymitis revisited: impact of molecular diagnostics on etiology and contemporary guideline recommendationsQ37842475
Features and applications of bacterial sialidases.Q37872238
Influence of urogenital infections and inflammation on semen quality and male fertilityQ37900190
Etiology and manifestations of epididymitis in young men: correlations with sexual orientationQ37901518
Host sialoglycans and bacterial sialidases: a mucosal perspectiveQ38004080
Uropathogenic Escherichia coli modulates innate immunity to suppress Th1-mediated inflammatory responses during infectious epididymitisQ38327739
Sialidase NEU4 hydrolyzes polysialic acids of neural cell adhesion molecules and negatively regulates neurite formation by hippocampal neuronsQ39384755
Purification and properties of rabbit spermatozoal acrosomal neuraminidaseQ39431122
Escherichia colibind to urinary bladder epithelium through nonspecific sialic acid mediated adherenceQ40626598
Uropathogenic Escherichia coli causes fibrotic remodelling of the epididymis.Q40662089
Sialidase inhibitors DAMPen sepsisQ43184791
Structural and functional integrity of spermatozoa is compromised as a consequence of acute uropathogenic E. coli-associated epididymitisQ44056776
P433issue34
P407language of work or nameEnglishQ1860
P921main subjectspermatozoonQ74560
glycocalyxQ898356
P304page(s)17717-17726
P577publication date2016-06-23
P1433published inJournal of Biological ChemistryQ867727
P1476titleDesialylation of Spermatozoa and Epithelial Cell Glycocalyx Is a Consequence of Bacterial Infection of the Epididymis
P478volume291

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cites work (P2860)
Q42369739Artificial Polysialic Acid Chains as Sialidase-Resistant Molecular-Anchors to Accumulate Particles on Neutrophil Extracellular Traps.
Q52592144Infectious, inflammatory and 'autoimmune' male factor infertility: how do rodent models inform clinical practice?