Receptors coupled to heterotrimeric G proteins of the G12 family

scientific article

Warning: Trying to access array offset on value of type null in /home/httpd/vhosts/renenyffenegger.ch/opendata.renenyffenegger.ch/Wikimedia/Wikidata/entity/main.php on line 159 Warning: Trying to access array offset on value of type null in /home/httpd/vhosts/renenyffenegger.ch/opendata.renenyffenegger.ch/Wikimedia/Wikidata/entity/main.php on line 159 Warning: foreach() argument must be of type array|object, null given in /home/httpd/vhosts/renenyffenegger.ch/opendata.renenyffenegger.ch/Wikimedia/Wikidata/entity/main.php on line 161
Receptors coupled to heterotrimeric G proteins of the G12 family is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.TIPS.2005.01.007
P698PubMed publication ID15749160

P2093author name stringNatalia A Riobo
David R Manning
P433issue3
P921main subjectG protein-coupled receptorQ38173
P304page(s)146-154
P577publication date2005-03-01
P13046publication type of scholarly workreview articleQ7318358
P1433published inTrends in Pharmacological SciencesQ2451474
P1476titleReceptors coupled to heterotrimeric G proteins of the G12 family
P478volume26

Reverse relations

cites work (P2860)
Q55244012A FRET-based biosensor for measuring Gα13 activation in single cells.
Q46606826A G(q/11)-coupled mutant histamine H(1) receptor F435A activated solely by synthetic ligands (RASSL).
Q28239827A nonsynonymous single-nucleotide polymorphism in the PDZ-Rho guanine nucleotide exchange factor (Ser1416Gly) modulates the risk of lung cancer in Mexican Americans
Q40264901A role for the G12 family of heterotrimeric G proteins in prostate cancer invasion
Q35013068A single lentiviral vector platform for microRNA-based conditional RNA interference and coordinated transgene expression
Q42637835Angiotensin II type-1 receptor regulates RhoA and Rho-kinase/ROCK activation via multiple mechanisms. Focus on "Angiotensin II induces RhoA activation through SHP2-dependent dephosphorylation of the RhoGAP p190A in vascular smooth muscle cells".
Q28581617Antagonist minigenes identify genes regulated by parathyroid hormone through G protein-selective and G protein co-regulated mechanisms in osteoblastic cells
Q46317385Antagonistic regulation of neurite morphology through Gq/G11 and G12/G13.
Q33727675CCK activates RhoA and Rac1 differentially through Galpha13 and Galphaq in mouse pancreatic acini.
Q36755415Central role of Gq in the hypertrophic signal transduction of angiotensin II in vascular smooth muscle cells
Q42937057Deconvolution of complex G protein-coupled receptor signaling in live cells using dynamic mass redistribution measurements.
Q36949575Distinct profiles of functional discrimination among G proteins determine the actions of G protein-coupled receptors
Q37248451Endothelial nitric oxide synthase inhibits G12/13 and rho-kinase activated by the angiotensin II type-1 receptor: implication in vascular migration
Q34580340G Protein and β-arrestin signaling bias at the ghrelin receptor
Q39795915G alpha 12 inhibits alpha2 beta1 integrin-mediated Madin-Darby canine kidney cell attachment and migration on collagen-I and blocks tubulogenesis
Q36804971G alpha12 is targeted to the mitochondria and affects mitochondrial morphology and motility.
Q33743722G protein subunit Galpha13 binds to integrin alphaIIbbeta3 and mediates integrin "outside-in" signaling
Q37284426G protein-coupled receptors go extracellular: RhoA integrates the integrins
Q28564687G-protein-coupled receptor agonists activate endogenous phospholipase Cepsilon and phospholipase Cbeta3 in a temporally distinct manner
Q34075403G12 Signaling through c-Jun NH2-Terminal Kinase Promotes Breast Cancer Cell Invasion
Q38089133G12/13-dependent signaling of G-protein-coupled receptors: disease context and impact on drug discovery
Q24647442Galpha12/13 regulate epiboly by inhibiting E-cadherin activity and modulating the actin cytoskeleton
Q36318560Genetic variation in G-protein-coupled receptors--consequences for G-protein-coupled receptors as drug targets
Q35918667Gα12 activation in podocytes leads to cumulative changes in glomerular collagen expression, proteinuria and glomerulosclerosis.
Q46538692Gα12 facilitates shortening in human airway smooth muscle by modulating phosphoinositide 3-kinase-mediated activation in a RhoA-dependent manner
Q38435836Gα12 gep oncogene deregulation of p53-responsive microRNAs promotes epithelial-mesenchymal transition of hepatocellular carcinoma.
Q47595585Gα12 regulates osteoclastogenesis by modulating NFATc1 expression
Q37550751Heterotrimeric G proteins and apoptosis: intersecting signaling pathways leading to context dependent phenotypes
Q34654532Heterotrimeric G-protein alpha-12 (Gα12) subunit promotes oral cancer metastasis.
Q36364445Heterotrimeric G-proteins: a short history
Q35010997Heterotrimeric Gi proteins link Hedgehog signaling to activation of Rho small GTPases to promote fibroblast migration
Q30990011Identification of novel species-selective agonists of the G-protein-coupled receptor GPR35 that promote recruitment of β-arrestin-2 and activate Gα13.
Q37405786Interaction of Protease-Activated Receptor 2 with G Proteins and β-Arrestin 1 Studied by Bioluminescence Resonance Energy Transfer
Q36486893Kaposi sarcoma-associated herpesvirus promotes tumorigenesis by modulating the Hippo pathway.
Q24328829LGR6 is a high affinity receptor of R-spondins and potentially functions as a tumor suppressor
Q50298453Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13
Q38044174Lysophospholipid receptor activation of RhoA and lipid signaling pathways
Q40019234Mouse EP3 alpha, beta, and gamma receptor variants reduce tumor cell proliferation and tumorigenesis in vivo.
Q85014016NOX2 activated by α1-adrenoceptors modulates hepatic metabolic routes stimulated by β-adrenoceptors
Q37761913Non-cell-autonomous signaling by Shh in tumors: challenges and opportunities for therapeutic targets.
Q24681482Novel cannabinoid receptors
Q37391849P2Y5 is a G(alpha)i, G(alpha)12/13 G protein-coupled receptor activated by lysophosphatidic acid that reduces intestinal cell adhesion
Q24323912PRR5L degradation promotes mTORC2-mediated PKC-δ phosphorylation and cell migration downstream of Gα12
Q36653811Phospholipase Cɛ links G protein-coupled receptor activation to inflammatory astrocytic responses
Q33669233Polyamines transduce the nongenomic, androgen-induced calcium sensitization in intestinal smooth muscle
Q33795938Polycystin-1 protein level determines activity of the Galpha12/JNK apoptosis pathway
Q51023608Potentiation of receptor responses induced by prolonged binding of Gα13 and leukemia-associated RhoGEF.
Q33223660Prediction of the coupling specificity of GPCRs to four families of G-proteins using hidden Markov models and artificial neural networks
Q37974268Probing heterotrimeric G protein activation: applications to biased ligands.
Q42123917Protease-activated receptor 1 (PAR1) coupling to Gq/11 but not to Gi/o or G12/13 is mediated by discrete amino acids within the receptor second intracellular loop
Q30439157Pulsatile equibiaxial stretch inhibits thrombin-induced RhoA and NF-kappaB activation
Q50437489RIC8A is essential for the organisation of actin cytoskeleton and cell-matrix interaction
Q42211176Receptor-G protein interaction studied by bioluminescence resonance energy transfer: lessons from protease-activated receptor 1.
Q37391229Regulation and physiological functions of G12/13-mediated signaling pathways
Q36940134Regulation of Rho guanine nucleotide exchange factors by G proteins
Q37395997Regulation of RhoGEF proteins by G12/13-coupled receptors
Q37038052Regulation of heterotrimeric G protein signaling in airway smooth muscle
Q45054292Regulation of phospholipase C-β(1) GTPase-activating protein (GAP) function and relationship to G(q) efficacy
Q37649264Regulation of smooth muscle contraction by small GTPases
Q36817694Regulation of thymus-dependent and thymus-independent production of immunoglobulin G subclasses by Galpha12 and Galpha13.
Q37726354Regulators of G protein signaling proteins as central components of G protein-coupled receptor signaling complexes
Q37766125Revisited and revised: is RhoA always a villain in cardiac pathophysiology?
Q36750023RhoGEF12 controls cardiac remodeling by integrating G protein- and integrin-dependent signaling cascades.
Q37473484Role of G12 proteins in oncogenesis and metastasis
Q35950300Role of Galpha12 and Galpha13 as novel switches for the activity of Nrf2, a key antioxidative transcription factor
Q34036069Role of protein kinase C and epidermal growth factor receptor signalling in growth stimulation by neurotensin in colon carcinoma cells
Q35557102Signalling mechanisms of RhoGTPase regulation by the heterotrimeric G proteins G12 and G13
Q36201833Stimulation of Dopamine D3 Receptor Attenuates Renal Ischemia-Reperfusion Injury via Increased Linkage With Gα12.
Q34650253The G12 family of heterotrimeric G proteins promotes breast cancer invasion and metastasis
Q39924947The Gq and G12 families of heterotrimeric G proteins report functional selectivity
Q38839503The adhesion G protein-coupled receptor G2 (ADGRG2/GPR64) constitutively activates SRE and NFκB and is involved in cell adhesion and migration
Q58733550The human brainome: network analysis identifies HSPA2 as a novel Alzheimer’s disease target
Q24318550The multiple personalities of the chemokine receptor CCR7 in dendritic cells
Q34156723The systematic annotation of the three main GPCR families in Reactome
Q35182945The α Subunit of the G Protein G13 Regulates Activity of One or More Gli Transcription Factors Independently of Smoothened
Q38144624Tubulin, actin and heterotrimeric G proteins: coordination of signaling and structure
Q42064855Unique interaction pattern for a functionally biased ghrelin receptor agonist