Mutations in β-Lactamase AmpC Increase Resistance of Pseudomonas aeruginosa Isolates to Antipseudomonal Cephalosporins.

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Mutations in β-Lactamase AmpC Increase Resistance of Pseudomonas aeruginosa Isolates to Antipseudomonal Cephalosporins. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/AAC.00825-15
P932PMC publication ID4576058
P698PubMed publication ID26248364

P50authorKaty JeannotQ61011948
P2093author name stringD Fournier
M Berrazeg
P Plésiat
Véronique Yvette Ntsogo Enguéné
I Broutin
S Loeffert
P2860cites workDetection of clonally related Escherichia coli isolates producing different CMY β-lactamases from a cystic fibrosis patientQ44942628
Analysis of antibiotic resistance gene expression in Pseudomonas aeruginosa by quantitative real-time-PCR.Q46918548
Characterization of β-lactamase and porin mutants of Enterobacteriaceae selected with ceftaroline + avibactam (NXL104).Q47570250
Contribution of asparagine 346 residue to the carbapenemase activity of CMY-2 β-lactamaseQ50911138
Pseudomonas aeruginosa isolates with modified beta-lactamase inducibility: effects on beta-lactam sensitivityQ54516014
Prevalence of AmpC over-expression in bloodstream isolates of Pseudomonas aeruginosaQ61833650
Genetic recombination in Pseudomonas aeruginosaQ73881599
Side chain SAR of bicyclic beta-lactamase inhibitors (BLIs). 1. Discovery of a class C BLI for combination with imipinemQ27658832
Avibactam and Class C  -Lactamases: Mechanism of Inhibition, Conservation of the Binding Pocket, and Implications for ResistanceQ27684678
Common Virulence Factors for Bacterial Pathogenicity in Plants and AnimalsQ28292772
Construction of improved Escherichia-Pseudomonas shuttle vectors derived from pUC18/19 and sequence of the region required for their replication in Pseudomonas aeruginosaQ29615291
Beta-lactam resistance response triggered by inactivation of a nonessential penicillin-binding proteinQ33422951
In vitro activity of ceftazidime+NXL104 against Pseudomonas aeruginosa and other non-fermentersQ34134689
Multiresistant Gram-negative bacteria: the role of high-risk clones in the dissemination of antibiotic resistanceQ34163308
Ceftolozane/tazobactam: a novel cephalosporin/β-lactamase inhibitor combination with activity against multidrug-resistant gram-negative bacilli.Q34393008
High frequency of hypermutable Pseudomonas aeruginosa in cystic fibrosis lung infection.Q34508854
Overexpression of AmpC and efflux pumps in Pseudomonas aeruginosa isolates from bloodstream infections: prevalence and impact on resistance in a Spanish multicenter studyQ34932869
Antibacterial-resistant Pseudomonas aeruginosa: clinical impact and complex regulation of chromosomally encoded resistance mechanismsQ35007624
Exploring sequence requirements for C₃/C₄ carboxylate recognition in the Pseudomonas aeruginosa cephalosporinase: Insights into plasticity of the AmpC β-lactamaseQ35014136
Activity of cefepime against ceftazidime- and cefotaxime-resistant gram-negative bacteria and its relationship to beta-lactamase levelsQ35326845
Pseudomonas aeruginosa may accumulate drug resistance mechanisms without losing its ability to cause bloodstream infectionsQ36095065
Resistance mechanisms of multiresistant Pseudomonas aeruginosa strains from Germany and correlation with hypermutationQ36295397
AmpC beta-lactamasesQ37366249
Bacterial hypermutation in cystic fibrosis, not only for antibiotic resistanceQ37794342
Interplay between chromosomal beta-lactamase and the MexAB-OprM efflux system in intrinsic resistance to beta-lactams in Pseudomonas aeruginosaQ39469881
Genotypic and phenotypic variation in Pseudomonas aeruginosa reveals signatures of secondary infection and mutator activity in certain cystic fibrosis patients with chronic lung infectionsQ39656697
Aminoglycoside efflux in Pseudomonas aeruginosa: involvement of novel outer membrane proteins.Q39731858
Development of a multilocus sequence typing scheme for the opportunistic pathogen Pseudomonas aeruginosa.Q40625683
Pseudomonas aeruginosa ceftolozane-tazobactam resistance development requires multiple mutations leading to overexpression and structural modification of AmpCQ41075944
Genetic markers of widespread extensively drug-resistant Pseudomonas aeruginosa high-risk clones.Q41183478
Carbapenem resistance in cystic fibrosis strains of Pseudomonas aeruginosa as a result of amino acid substitutions in porin OprD.Q41452848
Mutation-driven β-lactam resistance mechanisms among contemporary ceftazidime-nonsusceptible Pseudomonas aeruginosa isolates from U.S. hospitalsQ41757275
Population structure and antimicrobial susceptibility of both nonpersistent and persistent Pseudomonas aeruginosa isolates recovered from cystic fibrosis patientsQ41822095
Activity of a new cephalosporin, CXA-101 (FR264205), against beta-lactam-resistant Pseudomonas aeruginosa mutants selected in vitro and after antipseudomonal treatment of intensive care unit patientsQ41839265
Cephalosporinase and penicillinase activities of a β-lactamase from Pseudomonas pyocyaneaQ41918427
Resistance of Pseudomonas aeruginosa mutants with altered control of chromosomal beta-lactamase to piperacillin, ceftazidime, and cefsulodinQ42115498
Emergence of a mutL mutation causing multilocus sequence typing-pulsed-field gel electrophoresis discrepancy among Pseudomonas aeruginosa isolates from a cystic fibrosis patient.Q42152337
Molecular epidemiology and mechanisms of carbapenem resistance in Pseudomonas aeruginosaQ42612014
Differential beta-lactam resistance response driven by ampD or dacB (PBP4) inactivation in genetically diverse Pseudomonas aeruginosa strainsQ43077051
Extended-spectrum cephalosporinases in Pseudomonas aeruginosaQ43128351
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectPseudomonas aeruginosaQ31856
P304page(s)6248-6255
P577publication date2015-07-27
P1433published inAntimicrobial Agents and ChemotherapyQ578004
P1476titleMutations in β-Lactamase AmpC Increase Resistance of Pseudomonas aeruginosa Isolates to Antipseudomonal Cephalosporins
P478volume59

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cites work (P2860)
Q47218700Activity of Ceftolozane-Tazobactam against Carbapenem-Resistant, Non-Carbapenemase-Producing Pseudomonas aeruginosa and Associated Resistance Mechanisms.
Q38777049Activity of ceftolozane/tazobactam against surveillance and 'problem' Enterobacteriaceae, Pseudomonas aeruginosa and non-fermenters from the British Isles
Q59126430Association between possession of ExoU and antibiotic resistance in Pseudomonas aeruginosa
Q47748447Ceftolozane-Tazobactam for the Treatment of Multidrug-Resistant Pseudomonas aeruginosa Infections: Clinical Effectiveness and Evolution of Resistance.
Q53824657Ceftolozane/tazobactam for the treatment of XDR Pseudomonas aeruginosa infections.
Q60303457Deciphering the Evolution of Cephalosporin Resistance to Ceftolozane-Tazobactam in Pseudomonas aeruginosa
Q95831914Digital multiplex ligation assay for highly multiplexed screening of β-lactamase-encoding genes in bacterial isolates
Q46286684Diversity and regulation of intrinsic β-lactamases from non-fermenting and other Gram-negative opportunistic pathogens.
Q59811303Draft Genome Sequences of Two Pseudomonas aeruginosa Multidrug-Resistant Clinical Isolates, PAL0.1 and PAL1.1
Q89899478Epidemiology of β-Lactamase-Producing Pathogens
Q90028088Evaluation of in vitro activity of ceftazidime/avibactam and ceftolozane/tazobactam against MDR Pseudomonas aeruginosa isolates from Qatar
Q38741337Evolution of Pseudomonas aeruginosa Antimicrobial Resistance and Fitness under Low and High Mutation Rates.
Q45897898Evolved Aztreonam Resistance Is Multifactorial and Can Produce Hypervirulence in Pseudomonas aeruginosa
Q57789664Expression of Pseudomonas aeruginosa Antibiotic Resistance Genes Varies Greatly during Infections in Cystic Fibrosis Patients
Q55456610Failure of ceftolozane‐tazobactam salvage therapy in complicated pneumonia with lung abscess.
Q91720690Genomic Analysis Identifies Novel Pseudomonas aeruginosa Resistance Genes under Selection during Inhaled Aztreonam Therapy In Vivo
Q40056971Genomics and Susceptibility Profiles of Extensively Drug-Resistant (XDR) Pseudomonas aeruginosa from Spain.
Q38856197Host and Pathogen Biomarkers for Severe Pseudomonas aeruginosa Infections
Q89766030Hypermutator Pseudomonas aeruginosa exploits multiple genetic pathways to develop multidrug resistance during long-term infections in the airways of cystic fibrosis patients
Q63438192Identifying and exploiting genes that potentiate the evolution of antibiotic resistance
Q47769606In Vitro Comparison of Ceftolozane-Tazobactam to Traditional Beta-Lactams and Ceftolozane-Tazobactam as an Alternative to Combination Antimicrobial Therapy for Pseudomonas aeruginosa
Q40148490In Vivo Emergence of Resistance to Novel Cephalosporin-β-Lactamase Inhibitor Combinations through the Duplication of Amino Acid D149 from OXA-2 β-Lactamase (OXA-539) in Sequence Type 235 Pseudomonas aeruginosa.
Q88031346Inactivation of the Pseudomonas-Derived Cephalosporinase-3 (PDC-3) by Relebactam
Q57158084Interplay between Peptidoglycan Biology and Virulence in Gram-Negative Pathogens
Q49921578Mechanisms leading to in vivo ceftolozane/tazobactam resistance development during the treatment of infections caused by MDR Pseudomonas aeruginosa.
Q26747150New β-Lactamase Inhibitors in the Clinic
Q38862139Overcoming β-lactam resistance in Gram-negative pathogens
Q64089404Proteome profiling of Pseudomonas aeruginosa PAO1 identifies novel responders to copper stress
Q37643058Pseudomonas aeruginosa Lifestyle: A Paradigm for Adaptation, Survival, and Persistence
Q61455281Resistance to Ceftolozane/Tazobactam in Arising by AmpC- and Non-AmpC-Mediated Pathways
Q60301100Risk factors and prognosis of complicated urinary tract infections caused by in hospitalized patients: a retrospective multicenter cohort study
Q90029135Stochastic Gene Expression Influences the Selection of Antibiotic Resistance Mutations
Q56835140Susceptibility to ceftobiprole of respiratory-tract pathogens collected in the United Kingdom and Ireland during 2014-2015
Q52313185The Versatile Mutational Resistome of Pseudomonas aeruginosa.
Q89997000The latest advances in β-lactam/β-lactamase inhibitor combinations for the treatment of Gram-negative bacterial infections
Q89965183The β-Lactamase Inhibitor Boronic Acid Derivative SM23 as a New Anti-Pseudomonas aeruginosa Biofilm
Q92216886VNRX-5133 (Taniborbactam), a Broad-Spectrum Inhibitor of Serine- and Metallo-β-Lactamases, Restores Activity of Cefepime in Enterobacterales and Pseudomonas aeruginosa
Q40296000WCK 5107 (Zidebactam) and WCK 5153 Are Novel Inhibitors of PBP2 Showing Potent "β-Lactam Enhancer" Activity against Pseudomonas aeruginosa, Including Multidrug-Resistant Metallo-β-Lactamase-Producing High-Risk Clones
Q39120027What we may expect from novel antibacterial agents in the pipeline with respect to resistance and pharmacodynamic principles
Q52568071Whole-Genome Analysis of an Extensively Drug-Resistance Empedobacter falsenii Strain Reveals Distinct Features and the Presence of a Novel Metallo-ß-Lactamase (EBR-2).

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