Anti-albuminuric effects of spironolactone in patients with type 2 diabetic nephropathy: a multicenter, randomized clinical trial

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Anti-albuminuric effects of spironolactone in patients with type 2 diabetic nephropathy: a multicenter, randomized clinical trial is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S10157-015-1106-2
P932PMC publication ID4577308
P698PubMed publication ID25795029
P5875ResearchGate publication ID273833362

P50authorJun WadaQ37383314
P2093author name stringHirofumi Makino
Yutaka Oiso
Daisuke Koya
Daisuke Ogawa
Hisazumi Araki
Takashi Uzu
Masahiko Ando
Akira Nishiyama
Hiroyuki Kobori
Seiichi Matsuo
Keizo Kanasaki
Enyu Imai
Shoichi Maruyama
Sawako Kato
Motomitsu Goto
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Mineralocorticoid receptor blockade enhances the antiproteinuric effect of an angiotensin II blocker through inhibiting podocyte injury in type 2 diabetic rats.Q33714897
Relationship between urinary angiotensinogen and salt sensitivity of blood pressure in patients with IgA nephropathyQ35179398
Enhanced intrarenal angiotensinogen contributes to early renal injury in spontaneously hypertensive ratsQ36026810
Combination therapy with ACE inhibitors and angiotensin II receptor blockers to halt progression of chronic renal disease: pathophysiology and indicationsQ36033383
Urinary neutrophil gelatinase-associated lipocalin levels in comparison with glomerular filtration rate for evaluation of renal function in patients with diabetic chronic kidney diseaseQ36191746
Predictors of diabetic end-stage renal disease in JapanQ36262390
Change in proteinuria after adding aldosterone blockers to ACE inhibitors or angiotensin receptor blockers in CKD: a systematic reviewQ37063760
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Mineralocorticoid receptor blockade in addition to angiotensin converting enzyme inhibitor or angiotensin II receptor blocker treatment: an emerging paradigm in diabetic nephropathy: a systematic review.Q38169395
Revised equations for estimated GFR from serum creatinine in JapanQ39513402
Modification of mineralocorticoid receptor function by Rac1 GTPase: implication in proteinuric kidney diseaseQ39912709
Eplerenone-mediated aldosterone blockade prevents renal fibrosis by reducing renal inflammation, interstitial cell proliferation and oxidative stressQ43548036
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Spironolactone in addition to ACE inhibition to reduce proteinuria in patients with chronic renal diseaseQ43743641
Renoprotective effects of mineralocorticoid receptor blockers in patients with proteinuric kidney diseases.Q44245147
Effectiveness of aldosterone blockade in patients with diabetic nephropathyQ44269017
Spironolactone prevents early renal injury in streptozotocin-induced diabetic ratsQ45085855
Long-term effects of addition of mineralocorticoid receptor antagonist to angiotensin II receptor blocker in patients with diabetic nephropathy: a randomized clinical trial.Q45943305
Microvascular disease: what does the UKPDS tell us about diabetic nephropathy?Q46418538
Microalbuminuria reduction with telmisartan in normotensive and hypertensive Japanese patients with type 2 diabetes: a post-hoc analysis of The Incipient to Overt: Angiotensin II Blocker, Telmisartan, Investigation on Type 2 Diabetic Nephropathy (INQ46479723
Beneficial effects of adding spironolactone to recommended antihypertensive treatment in diabetic nephropathy: a randomized, double-masked, cross-over studyQ46670272
Effect of renin-angiotensin-aldosterone system triple blockade on non-diabetic renal disease: addition of an aldosterone blocker, spironolactone, to combination treatment with an angiotensin-converting enzyme inhibitor and angiotensin II receptor blQ46687656
Beneficial impact of spironolactone in diabetic nephropathyQ46826573
Aldosterone breakthrough during angiotensin II receptor blockade in hypertensive patients with diabetes mellitusQ46874844
GFR estimation using standardized serum cystatin C in JapanQ47264246
Reduction in microalbuminuria as an integrated indicator for renal and cardiovascular risk reduction in patients with type 2 diabetesQ50800640
Mineralocorticoid receptor blockade reduced oxidative stress in renal transplant recipients: a double-blind, randomized pilot studyQ51026854
Long-term effects of spironolactone on proteinuria and kidney function in patients with chronic kidney diseaseQ79226809
Spironolactone in type 2 diabetic nephropathy: Effects on proteinuria, blood pressure and renal functionQ79279587
Effect of combining ACE inhibition with aldosterone blockade on proteinuria and renal damage in experimental nephrosisQ79529985
Prevention of transition from incipient to overt nephropathy with telmisartan in patients with type 2 diabetesQ80049813
P433issue6
P921main subjectdiabetic nephropathyQ1129105
multicenter clinical trialQ6934595
P304page(s)1098-1106
P577publication date2015-03-21
P1433published inClinical and experimental nephrologyQ26842022
P1476titleAnti-albuminuric effects of spironolactone in patients with type 2 diabetic nephropathy: a multicenter, randomized clinical trial
P478volume19

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cites work (P2860)
Q64070851Aldosterone Antagonists Reduce the Risk of Cardiovascular Mortality in Dialysis Patients: A Meta-Analysis
Q37566950Blood pressure control in type 2 diabetic patients
Q91142607Effect of a novel nonsteroidal selective mineralocorticoid receptor antagonist, esaxerenone (CS-3150), on blood pressure and renal injury in high salt-treated type 2 diabetic mice
Q88727557Effects of RAAS Inhibitors in Patients with Kidney Disease
Q40965113Effects of mineralocorticoid receptor antagonists on the progression of diabetic nephropathy
Q93025188Efficacy and safety of dosage-escalation of low-dosage esaxerenone added to a RAS inhibitor in hypertensive patients with type 2 diabetes and albuminuria: a single-arm, open-label study
Q38734501Has RAAS Blockade Reached Its Limits in the Treatment of Diabetic Nephropathy?
Q28080717Improvements in the Management of Diabetic Nephropathy
Q36948557Randomized control trial for the assessment of the anti-albuminuric effects of topiroxostat in hyperuricemic patients with diabetic nephropathy (the ETUDE study).
Q101578601Role of mineralocorticoid receptor antagonists in kidney diseases
Q64228363Spironolactone alleviates diabetic nephropathy through promoting autophagy in podocytes
Q93169634The Ascent of Mineralocorticoid Receptor Antagonists in Diabetic Nephropathy
Q36297539Twenty years after ACEIs and ARBs: emerging treatment strategies for diabetic nephropathy
Q47781932Urinary peptidomics in kidney disease and drug research

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