The role of BAFF in immune function and implications for autoimmunity

scientific article

The role of BAFF in immune function and implications for autoimmunity is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1111/J.0105-2896.2005.00219.X
P698PubMed publication ID15790349

P2093author name stringSusan L Kalled
P2860cites workBAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growthQ22009942
TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune diseaseQ22254041
Tumor necrosis factor (TNF) receptor superfamily member TACI is a high affinity receptor for TNF family members APRIL and BLySQ24290135
Cr2, a candidate gene in the murine Sle1c lupus susceptibility locus, encodes a dysfunctional proteinQ24291950
Impaired IgA class switching in APRIL-deficient miceQ24313032
NF-AT activation induced by a CAML-interacting member of the tumor necrosis factor receptor superfamilyQ24314630
BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2Q27639845
Interaction of the TNF homologues BLyS and APRIL with the TNF receptor homologues BCMA and TACIQ28140973
Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiencyQ28190857
Expression of BCMA, TACI, and BAFF-R in multiple myeloma: a mechanism for growth and survivalQ28205125
BLyS and APRIL form biologically active heterotrimers that are expressed in patients with systemic immune-based rheumatic diseasesQ28205999
BAFF-R, a newly identified TNF receptor that specifically interacts with BAFFQ28213294
APRIL-deficient mice have normal immune system developmentQ28511017
BCMA is essential for the survival of long-lived bone marrow plasma cellsQ28587037
Normal induction but attenuated progression of germinal center responses in BAFF and BAFF-R signaling-deficient miceQ28587370
B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cellsQ28590517
B cell depletion in autoimmune diseaseQ33361142
Cutting edge: a role for B lymphocyte stimulator in systemic lupus erythematosusQ33928629
Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases.Q33951524
Loss of TACI causes fatal lymphoproliferation and autoimmunity, establishing TACI as an inhibitory BLyS receptorQ34178508
BAFF AND APRIL: a tutorial on B cell survivalQ34994661
Pathogenic roles of B cells in human autoimmunity; insights from the clinicQ35772863
The complement system in B cell regulationQ35781836
Maturation of marginal zone and follicular B cells requires B cell activating factor of the tumor necrosis factor family and is independent of B cell maturation antigen.Q36369679
Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim inhibits BCR stimulation-induced apoptosis and deletion of autoreactive B cellsQ36371743
Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestationsQ36375661
Balancing immunity and tolerance: deleting and tuning lymphocyte repertoiresQ37689611
Production of congenic mouse strains carrying genomic intervals containing SLE-susceptibility genes derived from the SLE-prone NZM2410 strainQ40941667
G-CSF-stimulated neutrophils are a prominent source of functional BLySQ41818295
Normal B cell homeostasis requires B cell activation factor production by radiation-resistant cellsQ42079747
Inverse association between circulating APRIL levels and serological and clinical disease activity in patients with systemic lupus erythematosusQ42211312
Accumulation of clonally related B lymphocytes in the cerebrospinal fluid of multiple sclerosis patientsQ42619341
BAFF mediates survival of peripheral immature B lymphocytesQ42944182
The level of BLyS (BAFF) correlates with the titre of autoantibodies in human Sjögren's syndromeQ43050637
T cell costimulation by the TNF ligand BAFF.Q43803679
Cutting edge: BLyS enables survival of transitional and mature B cells through distinct mediators.Q44021488
Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF.Q44223059
Cutting edge: germinal centers formed in the absence of B cell-activating factor belonging to the TNF family exhibit impaired maturation and functionQ44504176
CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+T cellsQ45971909
B lymphocyte stimulator overexpression in patients with systemic lupus erythematosus: longitudinal observations.Q46001110
Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire.Q46109491
Local production of B lymphocyte stimulator protein and APRIL in arthritic joints of patients with inflammatory arthritisQ46397162
Requirements for follicular exclusion and competitive elimination of autoantigen-binding B cells.Q46482871
Expansion or elimination of B cells in vivo: dual roles for CD40- and Fas (CD95)-ligands modulated by the B cell antigen receptor.Q46863693
Antigen-induced exclusion from follicles and anergy are separate and complementary processes that influence peripheral B cell fateQ46900158
Expression of B-cell-activating factor of the TNF family (BAFF) and its receptors in multiple sclerosisQ47274470
Cutting edge: BAFF regulates CD21/35 and CD23 expression independent of its B cell survival functionQ47283207
Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches.Q47365613
Expression of BAFF (BLyS) in T cells infiltrating labial salivary glands from patients with Sjögren's syndromeQ47739038
BAFF production by antigen-presenting cells provides T cell co-stimulation.Q51025017
Intracerebral expression of CXCL13 and BAFF is accompanied by formation of lymphoid follicle-like structures in the meninges of mice with relapsing experimental autoimmune encephalomyelitis.Q51027456
Dependence of germinal center B cells on expression of CD21/CD35 for survival.Q52039603
B cell-activating factor belonging to the TNF family acts through separate receptors to support B cell survival and T cell-independent antibody formation.Q54707196
Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren’s syndromeQ57212191
An Essential Role for BAFF in the Normal Development of B Cells Through a BCMA-Independent PathwayQ57230082
Plasma levels of B-lymphocyte stimulator increase with HIV disease progressionQ57387720
P921main subjectimmune functionQ124683452
P304page(s)43-54
P577publication date2005-04-01
P1433published inImmunological ReviewsQ15724582
P1476titleThe role of BAFF in immune function and implications for autoimmunity
P478volume204

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cites work (P2860)
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