review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.2174/1568009053765799 |
P698 | PubMed publication ID | 15892620 |
P2093 | author name string | Pia Vihinen | |
Risto Ala-aho | |||
Veli-Matti Kähäri | |||
P433 | issue | 3 | |
P304 | page(s) | 203-220 | |
P577 | publication date | 2005-05-01 | |
P1433 | published in | Current Cancer Drug Targets | Q332547 |
P1476 | title | Matrix metalloproteinases as therapeutic targets in cancer | |
P478 | volume | 5 |
Q39893638 | A method in enzymology for measuring hydrolytic activities in live cell environments |
Q35879531 | A novel biphenyl urea derivate inhibits the invasion of breast cancer through the modulation of CXCR4 |
Q39300436 | A novel taspine derivative, HMQ1611, suppresses adhesion, migration and invasion of ZR-75-30 human breast cancer cells |
Q38453906 | Advances in the understanding of the clinically relevant genetic pathways and molecular aspects of canine mammary tumours. Part 2: invasion, angiogenesis, metastasis and therapy |
Q36772800 | An animal model of buccal mucosa cancer and cervical lymph node metastasis induced by U14 squamous cell carcinoma cells |
Q36235557 | Antiangiogenic strategies in hepatocellular carcinoma: current status |
Q36407244 | Antiprotease therapy in cancer: hot or not? |
Q39212676 | Antisense MMP-9 RNA inhibits malignant glioma cell growth in vitro and in vivo |
Q35827087 | Antroquinonol Targets FAK-Signaling Pathway Suppressed Cell Migration, Invasion, and Tumor Growth of C6 Glioma |
Q36645684 | Apoptotic and anti-metastatic effects of the whole skin of Venenum bufonis in A549 human lung cancer cells |
Q37494812 | BEHAB/brevican requires ADAMTS-mediated proteolytic cleavage to promote glioma invasion. |
Q38815447 | BRD4 induces cell migration and invasion in HCC cells through MMP-2 and MMP-9 activation mediated by the Sonic hedgehog signaling pathway |
Q38952639 | Bmi-1 regulates the migration and invasion of glioma cells through p16. |
Q36621547 | Cassia tora L. (Jue-ming-zi) has anticancer activity in TCA8113 cells in vitro and exerts anti-metastatic effects in vivo |
Q43159584 | Characteristics of Expression of Matrix Metalloproteinases (MMP-2 and MMP-9) in Glottic Squamous Cell Carcinoma and Benign Vocal Fold Lesions |
Q37632925 | Chemical biology for understanding matrix metalloproteinase function |
Q51550158 | Chip gel electrophoresis as a tool for study of matrix metalloproteinase 9 interaction with metallothionein. |
Q38430546 | Clinical implications of compounds designed to inhibit ECM-modifying metalloproteinases. |
Q34094663 | Curcumin as a therapeutic agent: the evidence from in vitro, animal and human studies. |
Q39147062 | Curcumin suppresses colon cancer cell invasion via AMPK-induced inhibition of NF-κB, uPA activator and MMP9. |
Q37672093 | Current technological challenges in biomarker discovery and validation |
Q37288213 | Deguelin inhibits proliferation and migration of human pancreatic cancer cells in vitro targeting hedgehog pathway |
Q39041183 | Design of novel chemotherapeutic delivery systems for colon cancer therapy based on oral polymeric nanoparticles |
Q33829871 | Detection of gelatinase B activity in serum of gastric cancer patients. |
Q33234060 | Development of selective inhibitors and substrate of matrix metalloproteinase-12. |
Q38089795 | Diagnostic and prognostic role of matrix metalloproteases in cancer. |
Q43105872 | Dual MMP7-proximity-activated and folate receptor-targeted nanoparticles for siRNA delivery. |
Q42229992 | Effective nanoparticle-based gene delivery by a protease triggered charge switch |
Q35158799 | Effects of hepatocyte growth factor on collagen synthesis and matrix metalloproteinase production in keloids |
Q55234457 | Elongator promotes the migration and invasion of hepatocellular carcinoma cell by the phosphorylation of AKT. |
Q37799614 | Enzyme-triggered nanomedicine: drug release strategies in cancer therapy. |
Q34608344 | Estrogen inhibits renal cell carcinoma cell progression through estrogen receptor-β activation |
Q48125942 | Evaluation of [18 F]BR420 and [18 F]BR351 as radiotracers for MMP-9 imaging in colorectal cancer |
Q45157660 | Expression of matrix metalloproteinase-1, -7, -9, -13, Ki-67, and HER-2 in epithelial-myoepithelial salivary gland cancer |
Q79370590 | Expression profiles associated with aggressive behavior in Merkel cell carcinoma |
Q30401826 | Extracellularly activatable nanocarriers for drug delivery to tumors. |
Q39735864 | FAK is involved in invasion and metastasis of hepatocellular carcinoma |
Q53279967 | Fibroblasts in omentum activated by tumor cells promote ovarian cancer growth, adhesion and invasiveness. |
Q40736375 | Frequency of the common promoter polymorphism MMP2 -1306 C>T in a population from central Bulgaria |
Q24336577 | GOLPH3 regulates the migration and invasion of glioma cells though RhoA |
Q38215654 | Genistein inhibits human prostate cancer cell detachment, invasion, and metastasis |
Q38971909 | Girdin, an actin-binding protein, is critical for migration, adhesion, and invasion of human glioblastoma cells |
Q33503255 | Global gene expression profiling of human pleural mesotheliomas: identification of matrix metalloproteinase 14 (MMP-14) as potential tumour target |
Q36777388 | Hybrid ferritin nanoparticles as activatable probes for tumor imaging |
Q53589745 | Immunohistochemical analysis on MMP-2 and MMP-9 for wound age determination. |
Q42628541 | In Situ Imaging of Tissue Remodeling with Collagen Hybridizing Peptides. |
Q37575078 | In vitro and in vivo anti-cancer activities of Kuding tea (Ilex kudingcha C.J. Tseng) against oral cancer |
Q36157381 | Induction of Smad1 by MT1-MMP contributes to tumor growth |
Q27027856 | Inflammatory breast cancer: New factors contribute to disease etiology: A review |
Q34105995 | Inhibition of cancer cell invasion and metastasis by genistein |
Q39379865 | Inhibition of matrix metalloproteinase activities and tightening of tight junctions by diallyl disulfide in AGS human gastric carcinoma cells |
Q40742201 | Investigation of the role of MMP3 -1171insA polymorphism in cutaneous malignant melanoma - a preliminary study |
Q39472188 | Involvement of the Syk-mTOR pathway in follicular lymphoma cell invasion and angiogenesis. |
Q38265674 | Is there new hope for therapeutic matrix metalloproteinase inhibition? |
Q30366990 | Lipid-Based Drug Delivery Systems in Cancer Therapy: What Is Available and What Is Yet to Come. |
Q37679954 | Liposomal cancer therapy: exploiting tumor characteristics |
Q34068206 | Liposomal nanostructures for photosensitizer delivery |
Q30008735 | Loss of SH3GL2 promotes the migration and invasion behaviours of glioblastoma cells through activating the STAT3/MMP2 signalling. |
Q86815127 | Low density lipoprotein receptor-related protein 1 mediated endocytosis of β1-integrin influences cell adhesion and cell migration |
Q39889999 | Low-density lipoprotein receptor-related protein 1 promotes cancer cell migration and invasion by inducing the expression of matrix metalloproteinases 2 and 9. |
Q39754750 | Lysophosphatidic acid (LPA) effects on endometrial carcinoma in vitro proliferation, invasion, and matrix metalloproteinase activity |
Q38946777 | MMP-2 responsive polymeric micelles for cancer-targeted intracellular drug delivery |
Q54362749 | MMP-9 from sublethally irradiated tumor promotes Lewis lung carcinoma cell invasiveness and pulmonary metastasis. |
Q50916304 | Matrix Metalloproteinase Inhibitors as Investigational and Therapeutic Tools in Unrestrained Tissue Remodeling and Pathological Disorders. |
Q58257208 | Matrix metalloproteinase (MMP)-1, -9 and -13 as prognostic factors in salivary gland cancer |
Q46091951 | Matrix metalloproteinase (MMP)-7 in salivary gland cancer |
Q36009930 | Matrix metalloproteinase inhibitors as investigative tools in the pathogenesis and management of vascular disease |
Q39498514 | Matrix metalloproteinase-1 contribution to sarcoma cell invasion |
Q53323168 | Matrix metalloproteinase-9 expression in the normal mucosa-adenoma-dysplasia-adenocarcinoma sequence of the colon. |
Q38793764 | Matrix metalloproteinases (MMPs), the main extracellular matrix (ECM) enzymes in collagen degradation, as a target for anticancer drugs |
Q36644577 | Matrix metalloproteinases as potential targets in the venous dilation associated with varicose veins |
Q43179077 | Mechanistic studies of the triggered release of liposomal contents by matrix metalloproteinase-9. |
Q46216972 | Metalloproteinases 2 and 9 activity during promotion and progression stages of rat liver carcinogenesis |
Q36219151 | Metalloproteinases and their inhibitors are influenced by inhalative glucocorticoid therapy in combination with environmental dust reduction in equine recurrent airway obstruction |
Q33896649 | Mitogen-activated protein kinase kinase 4 (MAP2K4) promotes human prostate cancer metastasis |
Q51128003 | Molecular dynamics simulation study on the interaction of collagen-like peptides with gelatinase-A (MMP-2). |
Q58646108 | Monitoring of Enzymatic Proteolysis Using Self-Assembled Quantum Dot-Protein Substrate Sensors |
Q38165639 | Nanopreparations for organelle-specific delivery in cancer |
Q48220826 | Neferine Potentiates the Antitumor Effect of Cisplatin in Human Lung Adenocarcinoma Cells Via a Mitochondria-Mediated Apoptosis Pathway. |
Q42239363 | New and paradoxical roles of matrix metalloproteinases in the tumor microenvironment. |
Q90263333 | Nudol, a phenanthrene derivative from Dendrobium nobile, induces cell cycle arrest and apoptosis and inhibits migration in osteosarcoma cells |
Q37981645 | On the cutting edge of proprotein convertase pharmacology: from molecular concepts to clinical applications |
Q28087243 | Polymeric nanoparticles for targeted treatment in oncology: current insights |
Q47155578 | Prognostic Value of Molecular Markers and Implication for Molecular Targeted Therapies in Nasopharyngeal Carcinoma: An Update in an Era of New Targeted Molecules Development |
Q35613476 | Prognostic value of matrix metalloproteinases in oral squamous cell carcinoma |
Q51173435 | Proteolytic activity monitored by fluorescence resonance energy transfer through quantum-dot-peptide conjugates. |
Q57788844 | Puerarin 6″-O-xyloside possesses significant antitumor activities on colon cancer through inducing apoptosis |
Q53301416 | Radiofluorinated pyrimidine-2,4,6-triones as molecular probes for noninvasive MMP-targeted imaging. |
Q35791117 | Relevant molecular markers and targets |
Q34571866 | Resveratrol as a novel agent for treatment of multiple myeloma with matrix metalloproteinase inhibitory activity |
Q38955186 | S100A8/A9 regulates MMP-2 expression and invasion and migration by carcinoma cells |
Q27306938 | Selective Allosteric Inhibition of MMP9 Is Efficacious in Preclinical Models of Ulcerative Colitis and Colorectal Cancer |
Q40312065 | Silibinin inhibits invasion of oral cancer cells by suppressing the MAPK pathway |
Q38697200 | Structural modifications in polymeric micelles to impart multifunctionality for improved drug delivery |
Q36647895 | Structure-based organic synthesis of drug prototypes: a personal odyssey |
Q34391559 | Surfing the big WAVE: Insights into the role of WAVE3 as a driving force in cancer progression and metastasis |
Q38855031 | Targeting the Tumor Environment in Squamous Cell Carcinoma of the Head and Neck |
Q92812666 | The Association of Matrix Metalloproteinases with Chronic Kidney Disease and Peripheral Vascular Disease: A Light at the End of the Tunnel? |
Q55353823 | The Protein Extract of Chlorella minutissima Inhibits The Expression of MMP-1, MMP-2 and MMP-9 in Cancer Cells through Upregulation of TIMP-3 and Down Regulation of c-Jun. |
Q92959736 | The Rebirth of Matrix Metalloproteinase Inhibitors: Moving Beyond the Dogma |
Q55417393 | The association of semaphorin 5A with lymph node metastasis and adverse prognosis in cervical cancer. |
Q36098246 | The functional interplay between EGFR overexpression, hTERT activation, and p53 mutation in esophageal epithelial cells with activation of stromal fibroblasts induces tumor development, invasion, and differentiation |
Q36312509 | The history of matrix metalloproteinases: milestones, myths, and misperceptions |
Q33261566 | The roles of substrate thermal stability and P2 and P1' subsite identity on matrix metalloproteinase triple-helical peptidase activity and collagen specificity |
Q39689348 | Tissue inhibitor of metalloproteinase-2 regulates matrix metalloproteinase-2-mediated endothelial barrier dysfunction and breast cancer cell transmigration through lung microvascular endothelial cells |
Q57214751 | Trends in matrix metalloproteinase research from 1986–2007: a bibliometric study |
Q21245736 | Tumor cell invasion of collagen matrices requires coordinate lipid agonist-induced G-protein and membrane-type matrix metalloproteinase-1-dependent signaling |